Abstract：
:To investigate the protective effect of garlic powder on cadmium-induced toxicity sea bass liver, juvenile fishes where maintained under three food diets (diet 1: normal without garlic supply, diet 2: 2% garlic powder; diet 3: 6% garlic powder). After 30 days of specific diets, each group was injected with 500 μg kg-1of Cd. The control group was the one fed with normal diet and not injected with Cd. Liver Cd, Zn, and Se loads was assessed after 1 and 3 days of Cd injections. Moreover, antioxidant enzymes activities termed as catalase, superoxide dismutase, and glutathione peroxydase as well as their gene expression levels were monitored. Finally, metallothionein protein accumulation and its gene expression regulation (MTa) were determined. In fish fed with 2 and 6% garlic powder, the amounts of Cd, Zn, and Se significantly increase in liver tissues. Two percent garlic powder specific diet reversed the Cd-induced inhibition of catalase (CAT), superoxide dismutase (SOD), and gluthathione peroxydase (GPx) and restored the Cd-induced lipid peroxidation (MDA). The increase of liver metallothionein proteins as well as the MTa gene expression level under Cd influence was more pronounced in animals maintained for 30 days under garlic power 2% diet. Our data must be carefully considered in view of the garlic powder introduction in sea bass food composition at 2% since it is an efficient prevention against Cd-induced alterations.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Mosbah A,Guerbej H,Boussetta H,Bouraoui Z,Banni Mdoi
10.1007/s12011-017-1146-4subject
Has Abstractpub_date
2018-06-01 00:00:00pages
370-378issue
2eissn
0163-4984issn
1559-0720pii
10.1007/s12011-017-1146-4journal_volume
183pub_type
杂志文章abstract：:A survey based on 838 samples of milk obtained from 537 dairies covering 70 of 95 districts in France was organized to assess iodine content of milk and its contribution to total intake. Iodine levels were significantly higher in winter than in summer. Very low iodine contents (less than 25 micrograms I/kg) were found...
journal_title：Biological trace element research
pub_type： 杂志文章
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journal_title：Biological trace element research
pub_type： 杂志文章,随机对照试验
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更新日期：2011-12-01 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02916820
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journal_title：Biological trace element research
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pub_type： 杂志文章
doi：10.1007/BF02796636
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pub_type： 杂志文章,随机对照试验
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journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
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doi：10.1007/BF02990262
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journal_title：Biological trace element research
pub_type： 杂志文章
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更新日期：1985-09-01 00:00:00
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journal_title：Biological trace element research
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journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
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更新日期：2017-12-01 00:00:00
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更新日期：2016-04-01 00:00:00
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pub_type： 杂志文章
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journal_title：Biological trace element research
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journal_title：Biological trace element research
pub_type： 杂志文章
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journal_title：Biological trace element research
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journal_title：Biological trace element research
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journal_title：Biological trace element research
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