Sodium selenate partially corrects impaired functional responses in detrusor muscle in streptozotocin-induced diabetic rats.

Abstract:

:Selenium selenate was administered to streptozotocin-induced diabetic rats to assess its effects on the detrusor muscle. Thirty-two rats were divided into four groups of eight subjects each. The study animals were made diabetic by means of a single intravenous injection of streptozotocin (STZ). The responsiveness of the detrusor was improved in the group injected with sodium selenate. Diabetes caused significant increases in carbachol and beta,gamma-MeATP-evoked contractions and significant decrease of contractions induced by electrical stimulation. Isoprenaline-induced relaxation of the detrusor muscle was diminished by diabetes, whereas ATP relaxation appeared to be increased. Although adenosine-induced relaxations in controls and in diabetic rats were accompanied by unchanged responses in normoxic conditions, a significant enhancement in the detrusor muscle was observed during hypoxia. This enhancement of adenosine responsiveness in hypoxic conditions is inhibited in diabetes. Treatment with sodium selenate prevented alterations of both carbachol-induced contractility and isoprenaline-evoked relaxation, whereas nerve-mediated contractions and purinergic responses were not improved in diabetic rats after treatment. Our data suggest that changes in cholinergic and adrenergic responses were the result of selenium deficiency in diabetic rats.

journal_name

Biol Trace Elem Res

authors

Gür S,Cinel I

doi

10.1385/BTER:93:1-3:171

subject

Has Abstract

pub_date

2003-07-01 00:00:00

pages

171-88

issue

1-3

eissn

0163-4984

issn

1559-0720

pii

BTER-93-1-3-171

journal_volume

93

pub_type

杂志文章
  • Melatonin Ameliorates Neuropharmacological and Neurobiochemical Alterations Induced by Subchronic Exposure to Arsenic in Wistar Rats.

    abstract::An experimental study was conducted in Wistar rats to characterize the arsenic ("As")-induced alterations in neurobiochemistry in brain and its impact on neuropharmacological activities with or without the melatonin (MLT) as an antioxidant given exogenously. Male Wistar rats were randomly divided in to four groups of ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1537-1

    authors: Durappanavar PN,Nadoor P,Waghe P,Pavithra BH,Jayaramu GM

    更新日期:2019-07-01 00:00:00

  • Chromium, nickel, and arsenic determinations in human samples by thermal and epithermal neutron activation analyses.

    abstract::Both thermal and epithermal neutron activation analyses have been employed to determine chromium and nickel in lung tissue and arsenic in urine. Based on accuracy, precision, and detection limits, these techniques have been successfully used to analyze lung tissue from a deceased welder, who died, from cancer, and to ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02796646

    authors: Landsberger S,Simsons A

    更新日期:1987-08-01 00:00:00

  • Effects of selenium overexposure on glutathione peroxidase and thioredoxin reductase gene expressions and activities.

    abstract::Selenium (Se) is an essential trace element in animals and human, however, excess Se intake can result in adverse health effects. Se supplementation increased glutathione peroxidase (GSH-Px) and thioredoxin reductase (TR) expressions in Se-deficient rats. However, little information is available on the relationship be...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:89:2:165

    authors: Gan L,Liu Q,Xu HB,Zhu YS,Yang XL

    更新日期:2002-11-01 00:00:00

  • Comparative study of metals accumulation in cultured in vitro mycelium and naturally grown fruiting bodies of Boletus badius and Cantharellus cibarius.

    abstract::Cantharellus cibarius Fr. (chanterelle) and Boletus badius Pers. (bay bolete) harvested from natural sites in Poland were used to derive in vitro cultures. The optimal medium composition for cultures was developed. Concentrations of the chosen elements (Zn, Cu, Fe, Mg, Ni, and Cd) in mycelium samples were measured by ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9670-3

    authors: Reczyński W,Muszyńska B,Opoka W,Smalec A,Sułkowska-Ziaja K,Malec M

    更新日期:2013-06-01 00:00:00

  • Zinc supplement modulates oxidative stress and antioxidant values in rats with severe acute pancreatitis.

    abstract::Oxidative stress is a main factor in the pathogenesis of severe acute pancreatitis (SAP). The ability of zinc (Zn) to retard oxidative processes has been recognized for many years. This study aims to examine the levels of free oxygen radicals and antioxidant enzyme in SAP rats and know the effect of Zn supplementation...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-9971-1

    authors: Tang QQ,Su SY,Fang MY

    更新日期:2014-06-01 00:00:00

  • Different Accumulation of Elements in Proximal and Distal Parts of the Left Anterior Descending Artery Beneath the Myocardial Bridge.

    abstract::To elucidate the action of the myocardial bridge (MB) on the coronary artery, the authors first prepared the hearts with the MB located in the middle one third of the left anterior descending (LAD) artery and then investigated element accumulation in the LAD artery of the hearts with the MB by direct chemical analysis...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0498-x

    authors: Tohno Y,Tohno S,Minami T,Pakdeewong-Ongkana N,Suwannahoy P,Quiggins R

    更新日期:2016-05-01 00:00:00

  • Protective Effects of Dietary Garlic Powder Against Cadmium-induced Toxicity in Sea Bass Liver: a Chemical, Biochemical, and Transcriptomic Approach.

    abstract::To investigate the protective effect of garlic powder on cadmium-induced toxicity sea bass liver, juvenile fishes where maintained under three food diets (diet 1: normal without garlic supply, diet 2: 2% garlic powder; diet 3: 6% garlic powder). After 30 days of specific diets, each group was injected with 500 μg kg-1...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-017-1146-4

    authors: Mosbah A,Guerbej H,Boussetta H,Bouraoui Z,Banni M

    更新日期:2018-06-01 00:00:00

  • Ethanol Exacerbates Manganese-Induced Neurobehavioral Deficits, Striatal Oxidative Stress, and Apoptosis Via Regulation of p53, Caspase-3, and Bax/Bcl-2 Ratio-Dependent Pathway.

    abstract::This study investigated the effects of ethanol (EtOH) on manganese (Mn)-induced striatal toxicity in rat by evaluating the neurobehavioral changes, biochemical and molecular events in rats exposed to Mn alone at 30 mg/kg, or their combination with EtOH at 1.25- and 5-g/kg body weight for 35 consecutive days. Locomotiv...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1587-4

    authors: Nkpaa KW,Awogbindin IO,Amadi BA,Abolaji AO,Adedara IA,Wegwu MO,Farombi EO

    更新日期:2019-09-01 00:00:00

  • Zinc nutritional status in adolescents with Down syndrome.

    abstract::Studies have evidenced that zinc metabolism is altered in presence of Down syndrome, and zinc seems to have a relationship with the metabolic alterations usually present in this syndrome. In this work, the Zn-related nutritional status of adolescents with Down syndrome was evaluated by means of biochemical parameters ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-007-0061-5

    authors: Marques RC,de Sousa AF,do Monte SJ,Oliveira FE,do Nascimento Nogueira N,Marreiro DN

    更新日期:2007-01-01 00:00:00

  • Plasma copper, zinc, and selenium levels and correlates with metabolic syndrome components of lebanese adults.

    abstract::Zinc, copper, and selenium statuses were reported to be linked to the development of chronic diseases, especially coronary heart disease (CHD). Metabolic syndrome, a known CHD risk factor, was found to be highly prevalent in Lebanon. Nevertheless, no data are available on the statuses of plasma zinc, copper, and selen...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-008-8112-0

    authors: Obeid O,Elfakhani M,Hlais S,Iskandar M,Batal M,Mouneimne Y,Adra N,Hwalla N

    更新日期:2008-07-01 00:00:00

  • Clinical effects of cesium intake.

    abstract::The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However, no properly confirmed tumor regression was reported so...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/s12011-009-8486-7

    authors: Melnikov P,Zanoni LZ

    更新日期:2010-06-01 00:00:00

  • Effects of selenium-enriched Agaricus blazei Murill on liver metabolic dysfunction in mice, a comparison with selenium-deficient Agaricus blazei Murill and sodium selenite.

    abstract::In the present study, we investigated the effects of Se-enriched Agaricus blazei Murill (Se-AbM) on liver injury in mice induced by acute alcohol administration. Mice received ethanol (5 g/kg body weight (BW)) by gavage every 12 h for a total of 3 doses. Se-AbM was administrated before ethanol administration. Subseque...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0022-8

    authors: Yu L,Yang S,Sun L,Jiang YF,Zhu LY

    更新日期:2014-07-01 00:00:00

  • The Expression of Zinc Transporters Changed in the Intestine of Weaned Pigs Exposed to Zinc Chitosan Chelate.

    abstract::This study was conducted to investigate the effect of zinc chitosan chelate (CS-Zn) on zinc transporter expression and content of tissue zinc in weaned piglets. A total of 90 weaned pigs (Duroc × Landrace × Yorkshire) were randomly allocated to treatment groups with supplementation of 100 mg/kg zinc as ZnSO4, 100 mg/k...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0732-1

    authors: Lv M,Fu X,Hu L,Yue X,Han X

    更新日期:2016-12-01 00:00:00

  • Cigarette smoking and hyperglycemia increase renal response to low levels of cadmium in welders: cystatin C as a sensitive marker.

    abstract::The present study was undertaken to investigate the utility of cystatin C (CysC) as an early biomarker of cadmium (Cd)-induced renal injury. The study was carried out on 50 adult male individuals divided into five groups of 10 individuals as follows: control, welders, smoker welders, diabetic welders, and smoker diabe...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-9939-1

    authors: Harisa GI,Attia SM,Ashour AE,Abdallah GM,Omran GA,Touliabah HE

    更新日期:2014-06-01 00:00:00

  • Effects of Sodium Arsenite and Arsenate in Testicular Histomorphometry and Antioxidants Enzymes Activities in Rats.

    abstract::The main source of environmental arsenic exposure in most countries of the world is drinking water in which inorganic forms of arsenic predominate. The present study was aimed to test the impact of two different compounds of inorganic arsenic in histomorphometric and enzymatic parameters in the testes by oral expositi...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0523-0

    authors: Souza ACF,Marchesi SC,Domingues de Almeida Lima G,Ferraz RP,Santos FC,da Matta SLP,Machado-Neves M

    更新日期:2016-06-01 00:00:00

  • Compositional changes of human mitral valves with aging.

    abstract::To elucidate compositional changes of the mitral valve with aging, the authors investigated the relationships among element contents in the mitral valves. The subjects consisted of 10 men and 15 women, ranging in age from 65 to 102 yr. After the ordinary dissection, mitral valves, lower parts of the interventricular s...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:88:3:203

    authors: Tohno Y,Tohno S,Satoh H,Minami T,Moriwake Y,Azuma C,Ohnishi Y

    更新日期:2002-09-01 00:00:00

  • Chromium Is Elevated in Fin Whale (Balaenoptera physalus) Skin Tissue and Is Genotoxic to Fin Whale Skin Cells.

    abstract::Hexavalent chromium (Cr(VI)) is present in the marine environment and is a known carcinogen and reproductive toxicant. Cr(VI) is the form of chromium that is well absorbed through the cell membrane. It is also the most prevalent form in seawater. We measured the total Cr levels in skin biopsies obtained from healthy f...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0311-x

    authors: Wise CF,Wise SS,Thompson WD,Perkins C,Wise JP Sr

    更新日期:2015-07-01 00:00:00

  • Evaluation of zinc content in children's hair.

    abstract::The zinc content in the hair of 654 children living in various rural and industrial areas in southern Poland was assayed by means of the atomic absorption spectrometry, following the dry digestion procedure. The hair of girls exhibited statistically significant higher level of Zn than the boys' hair, although in the s...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02790111

    authors: Zachwieja Z,Chlopicka J,Schlegel-Zawadzka M,Zagrodzki P,Wypchlo J,Krośniak M

    更新日期:1995-01-01 00:00:00

  • Glucocorticoid and polyamine involvement in zinc uptake by COMMA-1D mammary epithelial cells.

    abstract::The objective was to determine if a mammary cell line shows glucocorticoid stimulation of Zn uptake, and to determine whether polyamines mediate this stimulation. 65Zn uptake by COMMA-1D mouse mammary epithelial cells over a 24-h period increased significantly in cells administered 10(-7) or 10(-6) M hydrocortisone. I...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783193

    authors: Allen JC,Vaillancourt SJ,Haedrich L

    更新日期:1993-11-01 00:00:00

  • Bromide kinetics and distribution in the rat. I. Biokinetics of 82Br-bromide.

    abstract::Biological half-lives of bromine in 15 different organs and tissues of the rat, in addition to the whole-body half-life, were determined by measuring the radioactive concentration of 82Br-bromide in samples of tissues collected at the time intervals of 12-396 h from animals that continuously (up to 17 d) received 82Br...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:76:1:57

    authors: Pavelka S,Babický A,Vobecký M,Lener J,Svandová E

    更新日期:2000-07-01 00:00:00

  • Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.

    abstract::The relationship between selenium (Se) deficiency-induced cardiac malfunction and endoplasmic reticulum (ER) stress is poorly understood. In the present study, 18 weaning Sprague Dawley rats were randomly fed with three different Se diets, and myocardial glutathione peroxidase (GPx) activity was measured by an enzyme ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9834-1

    authors: Wang SQ,Niu XL,Liu ZW,Zhu YH,Gao DF

    更新日期:2013-12-01 00:00:00

  • Application of nuclear analytical techniques using long-life sealed-tube neutron generators.

    abstract::The new range of sealed-tube neutron generators developed by SODERN appears to be appropriate for the industrial environment. The main characteristics are the high emission stability during the very long lifetime of the tube, flexible pulsed mode capability, safety in operation with no radiation in "off" state, and th...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917309

    authors: Bach P,Cluzeau S,Lambermont C

    更新日期:1994-10-01 00:00:00

  • Selenium Deficiency Downregulates Selenoproteins and Suppresses Immune Function in Chicken Thymus.

    abstract::Selenoproteins and selenium (Se) play important roles in the immune system. Selenoprotein expression in the immune system of mammals is sensitive to dietary Se levels; however, little is known about the expression of selenoproteins and their immune functions in the chicken thymus. We assessed selenoprotein gene expres...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0282-y

    authors: Khoso PA,Yang Z,Liu C,Li S

    更新日期:2015-09-01 00:00:00

  • Effects of dietary zinc levels on the activities of enzymes, weights of organs, and the concentrations of zinc and copper in growing rats.

    abstract::Zinc (Zn) is an essential nutrient that is required in humans and animals for many physiological functions, including immune and antioxidant function, growth, and reproduction. The present study was performed to investigate the effects of three Zn levels, including Zn adequate (35.94 mg/kg, as a control), Zn deficienc...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:107:2:153

    authors: Sun JY,Jing MY,Weng XY,Fu LJ,Xu ZR,Zi NT,Wang JF

    更新日期:2005-11-01 00:00:00

  • Effect of peroxovanadate compound on phenylalanine hydroxylase gene expression.

    abstract::Vanadium, a trace element in human cells and regarded as an essential nutrient, plays an active role in all tissues. It is known that peroxovanadate-nicotinic acid (POV), a complex compound of vanadium, can decrease hyperglycemia; however, its biochemical mechanism remains unclear. The object of the present study is t...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:74:3:237

    authors: Wang YL,Yu B

    更新日期:2000-06-01 00:00:00

  • Studies of the interaction between boron and calcium, and its modification by magnesium and potassium, in rats. Effects on growth, blood variables, and bone mineral composition.

    abstract::Two experiments were performed to confirm that boron interacts with calcium, and that this interaction can be modified by dietary magnesium and potassium in the rat. Upon manipulating the dietary variables listed above, it was found that under certain conditions, boron and calcium deprivation similarly affected severa...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783768

    authors: Nielsen FH,Shuler TR

    更新日期:1992-12-01 00:00:00

  • Selenium and mercury in native and introduced fish species of patagonian lakes, Argentina.

    abstract::A survey of mercury (Hg) and selenium (Se) contents was performed in fish collected from lakes located in two National Parks of the northern patagonian Andean range. Two native species, catfish (Diplomystes viedmensis) and creole perch (Percichthys trucha), and three introduced species, brown trout (Salmo trutta), rai...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-007-8059-6

    authors: Arribére MA,Ribeiro Guevara S,Bubach DF,Arcagni M,Vigliano PH

    更新日期:2008-04-01 00:00:00

  • Assessment of Cu-Zn EDTA Parenteral Toxicity in Calves.

    abstract::Copper (Cu) parenteral administration is used in a beef cow-calf operations to prevent or correct Cu deficiency in bovines. At present, Zinc (Zn) salts have been incorporated to complement Cu antioxidant effect. A risk of hepatotoxicity generated by overdose is a negative consequence of injectable Cu application. Cu-Z...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-017-0965-7

    authors: Fazzio LE,Rosa DE,Picco SJ,Mattioli GA

    更新日期:2017-10-01 00:00:00

  • Developmental Neurotoxicity of Arsenic: Involvement of Oxidative Stress and Mitochondrial Functions.

    abstract::Over the last decade, there has been an increased concern about the health risks from exposure to arsenic at low doses, because of their neurotoxic effects on the developing brain. The exact mechanism underlying arsenic-induced neurotoxicity during sensitive periods of brain development remains unclear, although enhan...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1286-1

    authors: Chandravanshi LP,Gupta R,Shukla RK

    更新日期:2018-11-01 00:00:00

  • The chemical composition of bananas market basket values, 1968-1980.

    abstract::Forty-six elements have been detected in fresh banana pulp purchased weekly in Pittsburgh, PA for the past twelve years (1968-1980). Samples were prepared by lyophilization or low temperature ashing. Analyses were performed using X-ray fluorescence spectrometry, optical emission spectrometry, atomic absorption spectro...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02789122

    authors: Cowgill UM

    更新日期:1981-03-01 00:00:00