Chromium Is Elevated in Fin Whale (Balaenoptera physalus) Skin Tissue and Is Genotoxic to Fin Whale Skin Cells.

Abstract:

:Hexavalent chromium (Cr(VI)) is present in the marine environment and is a known carcinogen and reproductive toxicant. Cr(VI) is the form of chromium that is well absorbed through the cell membrane. It is also the most prevalent form in seawater. We measured the total Cr levels in skin biopsies obtained from healthy free-ranging fin whales from the Gulf of Maine and found elevated levels relative to marine mammals in other parts of the world. The levels in fin whale biopsies ranged from 1.71 to 19.6 μg/g with an average level of 10.07 μg/g. We also measured the cytotoxicity and genotoxicity of Cr(VI) in fin whale skin cells. We found that particulate and soluble Cr(VI) are both cytotoxic and genotoxic to fin whale skin cells in a concentration-dependent manner. The concentration range used in our cell culture studies used environmentally relevant concentrations based on the biopsy measurements. These data suggest that Cr(VI) may be a concern for whales in the Gulf of Maine.

journal_name

Biol Trace Elem Res

authors

Wise CF,Wise SS,Thompson WD,Perkins C,Wise JP Sr

doi

10.1007/s12011-015-0311-x

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

108-17

issue

1

eissn

0163-4984

issn

1559-0720

journal_volume

166

pub_type

杂志文章
  • A Study of the Possible Harmful Effects of Cosmetic Beauty Products on Human Health.

    abstract::The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0477-2

    authors: Kaličanin B,Velimirović D

    更新日期:2016-04-01 00:00:00

  • Effects of Different Doses of Calcium on the Mitochondrial Apoptotic Pathway and Rho/ROCK Signaling Pathway in the Bone of Fluorosis Rats.

    abstract::For this study, we investigate more deeply the effect calcium (Ca) develops on the mechanism underlying fluoride-triggered osteocyte apoptosis. We detected the morphology of osteocytes by HE staining, mitochondrial microstructure by using the transmission electron microscope, and the biochemical indexes related to bon...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02305-6

    authors: Yang J,Zhu Y,Zhang D,Yan Z,Zhao Y,Manthari RK,Cheng X,Wang J,Wang J

    更新日期:2020-07-25 00:00:00

  • Association Between Copper, Zinc, Iron, and Selenium Intakes and TC/HDL-C Ratio in US Adults.

    abstract::The trace minerals zinc, copper, iron, and selenium are essential micronutrients, and because of their antioxidant activity, they are hypothesized to improve cardiovascular health. However, their associations with different risk levels for cardiovascular diseases are less clear. Data from the National Health and Nutri...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01979-x

    authors: Ma X,Jiang S,Yan S,Li M,Wang C,Pan Y,Sun C,Jin L,Yao Y,Li B

    更新日期:2020-09-01 00:00:00

  • Evaluation of Trace Element Contamination and Health Risks of Medicinal Herbs Collected from Unpolluted and Polluted Areas in Sichuan Province, China.

    abstract::Trace element contamination in Chinese herbal medicines has been recognized as a potential health concern for consumers. To assess the health risk to the herb-consuming population, nine trace elements (Cu, Cd, Cr, Mo, Ni, Pb, Sr, Zn, and As) were investigated based on their concentrations in three common medicinal pla...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02539-4

    authors: Gao J,Zhang D,Uwiringiyimana E,Proshad R,Ugurlu A

    更新日期:2021-01-03 00:00:00

  • Application of nuclear analytical techniques using long-life sealed-tube neutron generators.

    abstract::The new range of sealed-tube neutron generators developed by SODERN appears to be appropriate for the industrial environment. The main characteristics are the high emission stability during the very long lifetime of the tube, flexible pulsed mode capability, safety in operation with no radiation in "off" state, and th...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917309

    authors: Bach P,Cluzeau S,Lambermont C

    更新日期:1994-10-01 00:00:00

  • Effect of Selenium Nanoparticle Supplementation on Tissue Inflammation, Blood Cell Count, and IGF-1 Levels in Spinal Cord Injury-Induced Rats.

    abstract::Selenium is known to be a neuroprotective agent in respect to a number of neuronal diseases and pain. The aim of this study was to evaluate the neuroprotective effect of the oral administration of selenium nanoparticles in rats with spinal cord injury (SCI). Forty adult female rats were randomly assigned to two equal ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1371-5

    authors: Javdani M,Habibi A,Shirian S,Kojouri GA,Hosseini F

    更新日期:2019-01-01 00:00:00

  • Protective role of selenium on pepper exposed to cadmium stress during reproductive stage.

    abstract::The aim of the present study was to examine the effects of exogenous selenium (Se) supplementation on the tolerance of pepper (Capsicum annuum L.) cv. Suryamukhi Cluster plants to cadmium (Cd) phytotoxicity at the reproductive stage. The pepper plants were supplied with Cd (0, 0.25 or 0.50 mM) and Se (0, 3 or 7 μM), i...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0028-2

    authors: Mozafariyan M,Shekari L,Hawrylak-Nowak B,Kamelmanesh MM

    更新日期:2014-07-01 00:00:00

  • Inhibition of glutathione reductase by cadmium ion in some rabbit tissues and the protective role of dietary selenium.

    abstract::This study is aimed at investigating the inhibitory effect of cadmium ion on glutathione reductase activity of rabbit brain and liver and the relationship of this effect with dietary selenium. For this purpose, one group of New Zealand rabbits were fed a selenium-deficient diet, another group was fed a selenium-rich d...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/bter:91:2:151

    authors: Ulusu N,Acan N,Turan B,Tezcan E

    更新日期:2003-02-01 00:00:00

  • ATP in cellular calcium-overload by trivalent metal ions.

    abstract::Extracellular Ca2+-influx induced by trivalent metal ions (Fe3+, Al3+, Cr3+, In3+, Ga3+, and La3+) in Ehrlich carcinoma cells is enhanced by ATP. This action seems to be related to the high coordination capacity of the ATP ligand that inhibits the polymerization of the solvated cations taking place at physiological pH...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02820027

    authors: Anghileri LJ,Thouvenot P

    更新日期:1998-04-01 00:00:00

  • Effects of gestational cadmium exposure on pregnancy outcome and development in the offspring at age 4.5 years.

    abstract::The objective of the present study was to evaluate the potential effect of maternal cadmium exposure on pregnancy outcome and development in the offspring at age 4.5 years. Between November 2002 and December 2003, 109 normal pregnant women were enrolled in our cohort from Da-Ye Country, Hubei Province in Central China...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-009-8391-0

    authors: Tian LL,Zhao YC,Wang XC,Gu JL,Sun ZJ,Zhang YL,Wang JX

    更新日期:2009-12-01 00:00:00

  • Investigating the Essentiality and Requirements of Iron from the Ancient to the Present.

    abstract::This review discusses the development of studies that evaluated the essentiality and requirements of iron from the ancient to the present. The therapeutic effects of iron compounds were recognized by the ancient Greeks and Romans. The earliest recognition of the essentiality of iron was stated by Paracelsus, a disting...

    journal_title:Biological trace element research

    pub_type: 历史文章,杂志文章,评审

    doi:10.1007/s12011-018-1584-7

    authors: Yokoi K

    更新日期:2019-03-01 00:00:00

  • Effects of traces of rare earth elements on the protozoan Blepherisma and on mice.

    abstract::The growth of the protozoan Blepherisma is stimulated by Lanthanum (La) at concentrations as low as 0.32 ppm. In mice Yttrium (Y) and Ytterbium (Yb) are absorbed, accumulated, and metabolized. Both rare earth elements (RE) exhibit a high affinity for teeth and bones, accumulation occurs and metabolism is slow. In the ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02795448

    authors: Zhang WD,Li FQ,Zhang XY,Chen Y

    更新日期:1988-09-01 00:00:00

  • Effect of form of iron on nickel deprivation in the rat : Liver content of copper, iron, manganese, and zinc.

    abstract::In three fully crossed, factorially arranged, completely randomized experiments, female weanling rats were fed a basal diet (containing about 10 ng of nickel and 2.3 μg of iron/g) supplemented with graded levels of nickel and iron. Iron was supplemented to the diet in experiment 1 at levels of 0, 25, 50, and 100 μg/g ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02990121

    authors: Nielsen FH,Shuler TR

    更新日期:1981-09-01 00:00:00

  • Validity of hair mineral testing.

    abstract::The variance of testing was compared between the College of American Pathologists clinical survey and that of a recent review about hair mineral testing. The review suggested that the accuracy of hair mineral testing was unreliable. In general, there was a greater range of variance in the College of American Pathologi...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:87:1-3:001

    authors: Shamberger RJ

    更新日期:2002-07-01 00:00:00

  • Cadmium-induced liver, heart, and spleen lipid peroxidation in rats and protection by selenium.

    abstract::The purpose of this study was to evaluate the effects of cadmium-induced peroxidative damage to rat liver, heart, and spleen. Sprague-Dawley rats were injected subcutaneously with a single dose of 25, 125, 500, or 1250 microg Cd/kg and evaluated 6, 12, 24, or 72 h later. Liver, heart, and spleen were analyzed for lipi...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:78:1-3:219

    authors: Yiin SJ,Chern CL,Sheu JY,Lin TH

    更新日期:2000-01-01 00:00:00

  • Effect of various clinical variables on total intracellular magnesium in hospitalized normomagnesemic diabetic patients before discharge.

    abstract::Deficiency of intracellular magnesium (icMg) may coexist with normal serum Mg levels. Little is known about clinical and pharmacological factors affecting icMg in normomagnesemic patients with diabetes mellitus (DM). Moreover, no information exists regarding the icMg state in diabetic patients after acute illness and ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-007-8024-4

    authors: Gorelik O,Efrati S,Berman S,Almoznino-Sarafian D,Alon I,Shteinshnaider M,Cohen N

    更新日期:2007-01-01 00:00:00

  • Effects of ionic valency of interacting metal elements in ion uptake by carrot (Daucas carota cv. U.S. harumakigosun).

    abstract::Interaction of elements in the course of element uptake by carrot (Daucas carota cv. U.S. harumakigosun) exerted by the addition of elements, such as Rb, Zn, and Al, was investigated. For the purpose of precise evaluation of uptake behavior, the simultaneous determination of absorption of Na, Be, Sr, Mn, Co, Zn, Ce, P...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/bter:84:1-3:197

    authors: Ozaki T,Ambe S,Minai Y,Enomoto S,Yatagai F,Abe T,Yoshida S,Makide Y

    更新日期:2001-01-01 00:00:00

  • Determination of arsenic in scalp hair of children and its correlation with drinking water in exposed areas of Sindh Pakistan.

    abstract::This study was focused on the analysis of arsenic (As) levels in scalp hair of children (age, <10 years) collected from two towns of Khairpur, Pakistan, to evaluate the effects of As-contaminated groundwater. For comparative purposes, scalp hair samples of children were also collected from that area having low levels ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8866-z

    authors: Kazi TG,Baig JA,Shah AQ,Arain MB,Jamali MK,Kandhro GA,Afridi HI,Kolachi NF,Khan S,Wadhwa SK,Shah F

    更新日期:2011-10-01 00:00:00

  • Plasma levels of trace elements have an implication on interferon treatment of children with chronic hepatitis B infection.

    abstract::This study evaluated the plasma levels of trace elements in children with chronic hepatitis B virus (HBV) infection and assessed whether they can be a factor that affects the response to interferon alpha (IFN-alpha) treatment. The study included 35 cases (ten girls, 25 boys) aged 3-13 years with chronic HBV infection ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-009-8507-6

    authors: Balamtekin N,Kurekci AE,Atay A,Kalman S,Okutan V,Gokcay E,Aydin A,Sener K,Safali M,Ozcan O

    更新日期:2010-06-01 00:00:00

  • Combined effect of high-fat diet and copper deficiency during gestation on fetal copper status in the rat.

    abstract::We have previously shown that a low-copper (Cu) diet produced alterations in placental Cu transport and fetal Cu stores. Because Cu deficiency has been associated with lipid deposition in rat dam liver, we hypothesized that a high fat intake, a prevalent dietary habit in many populations, may worsen fetal Cu status an...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02784069

    authors: Ebesh O,Barone A,Harper RG,Wapnir RA

    更新日期:1999-02-01 00:00:00

  • Induction of rat liver glutathione transferase isoenzyme 7-7 by lead nitrate.

    abstract::The glutathione transferase (GST) activity of rat liver cytosolic preparations with ethacrynic acid (EA) and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydro-benzo(a)pyrene (BPDE) as substrates, increased by 125 and 350%, respectively, in animals that had been treated with a single intraveno...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917265

    authors: Dock L

    更新日期:1989-07-01 00:00:00

  • Effects of zinc on interleukins and antioxidant enzyme values in psoriasis-induced mice.

    abstract::The effects of zinc chloride (ZnCl2), disodium zinc ethylenediamine tetraacetate (Zn-EDTA), and zinc gluconate (Zn-GLU) on the antioxidant enzyme activities and levels of interleukins (ILs) in psoriasis-induced mice were studied. One hundred twenty female mice were randomly divided into six groups with 20 mice in each...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9799-0

    authors: Yin LL,Zhang Y,Guo DM,An K,Yin MS,Cui X

    更新日期:2013-12-01 00:00:00

  • Neuroprotective Effect of Portulaca oleraceae Ethanolic Extract Ameliorates Methylmercury Induced Cognitive Dysfunction and Oxidative Stress in Cerebellum and Cortex of Rat Brain.

    abstract::Methylmercury (MeHg) is highly toxic, and its principal target tissue in human is the nervous system, which has made MeHg intoxication a public health concern for many decades. Portulaca oleraceae (purslane), a member of the Portulacaceae family, is widespread as a weed and has been ranked the eighth most common plant...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0546-6

    authors: Sumathi T,Christinal J

    更新日期:2016-07-01 00:00:00

  • Cigarette smoking and hyperglycemia increase renal response to low levels of cadmium in welders: cystatin C as a sensitive marker.

    abstract::The present study was undertaken to investigate the utility of cystatin C (CysC) as an early biomarker of cadmium (Cd)-induced renal injury. The study was carried out on 50 adult male individuals divided into five groups of 10 individuals as follows: control, welders, smoker welders, diabetic welders, and smoker diabe...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-9939-1

    authors: Harisa GI,Attia SM,Ashour AE,Abdallah GM,Omran GA,Touliabah HE

    更新日期:2014-06-01 00:00:00

  • Effect of dietary zinc on the levels and distribution of Fatty acids and vitamin A in blood plasma chylomicrons.

    abstract::The aim of this work was to explore the effects of a low- and high-zinc diet and vitamin Aon the distribution of fatty acids in chylomicrons. Mongolian Gerbils were fed a basal diet (for 3 wk) containing 8 or 38 mg zinc/kg of feed (low-zinc group [termed LZ group] and saturated zinc group [termed SZ group], respective...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:112:2:145

    authors: Cerovic A,Miletic I,Sobajic S,Blagojevic D,Jones DR,Poznanic M,Radusinovic M

    更新日期:2006-08-01 00:00:00

  • The Co-induced Effects of Molybdenum and Cadmium on Antioxidants and Heat Shock Proteins in Duck Kidneys.

    abstract::Molybdenum (Mo) is an essential element for human beings and animals; however, high dietary intake of Mo can lead to adverse reactions. Cadmium (Cd) is harmful to health. To investigate the toxicity of Mo combined with Cd in duck kidneys, 240 ducks were randomly divided into six groups and treated with a commercial di...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0348-x

    authors: Xia B,Cao H,Luo J,Liu P,Guo X,Hu G,Zhang C

    更新日期:2015-11-01 00:00:00

  • The susceptibility to stress-induced gastric injury of rats exposed to cadmium.

    abstract::In this experimental study, the effect of cadmium on cold and restraint stress-induced gastric lesions has been studied. Rats received 15 micrograms/mL cadmium-containing water for 30 d, and at the end of this period, they were subjected to cold and restraint stress. Cadmium accumulation in gastric mucosa was associat...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02790120

    authors: Oner G,Izgüt VN,Sentürk UK

    更新日期:1995-01-01 00:00:00

  • Zinc uptake by blood cells of rats in zinc deficiency and inflammation.

    abstract::In zinc deficiency, the function of leukocytes is impaired. However, the results of studies on the zinc concentration of blood cells in zinc deficiency are conflicting, probably in part because of technical and analytical problems. The aim of this study was to investigate, under standard conditions, the uptake of 65Zn...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783726

    authors: Naber TH,van den Hamer CJ,van den Broek WJ,van Tongeren JH

    更新日期:1992-11-01 00:00:00

  • Na+/I- symporter and type 3 iodothyronine deiodinase gene expression in amniotic membrane and placenta and its relationship to maternal thyroid hormones.

    abstract::Placental type 3 iodothyronine deiodinase (D3) potentially protects the fetus from the elevated maternal thyroid hormones. Na(+)/I(-) symporter (NIS) is a plasma membrane glycoprotein, which mediates active iodide uptake. Our objectives were to establish the distribution of NIS and D3 gene expressions in the placenta ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9748-y

    authors: Akturk M,Oruc AS,Danisman N,Erkek S,Buyukkagnici U,Unlu E,Tazebay UH

    更新日期:2013-09-01 00:00:00

  • Zinc, ethanol, and lipid peroxidation in adult and fetal rats.

    abstract::Studies were performed on adult and fetal rats receiving either a zinc-deficient (<0.5 ppm) diet and/or ethanol (20%) throughout pregnancy. Liver zinc levels were depressed in fetuses exposed toin utero zinc deficiency, but brain zinc levels were unchanged. Ethanol had no effect on the concentration of zinc in the sev...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02795685

    authors: Dreosti IE,Partick EJ

    更新日期:1987-12-01 00:00:00