Abstract：
:Studies were performed on adult and fetal rats receiving either a zinc-deficient (<0.5 ppm) diet and/or ethanol (20%) throughout pregnancy. Liver zinc levels were depressed in fetuses exposed toin utero zinc deficiency, but brain zinc levels were unchanged. Ethanol had no effect on the concentration of zinc in the several fetal and adult tissues studies. Lipid peroxidation, as measured by endogenous levels of malondialdehyde (MDA) increased following food restriction, zinc improverishment, and alcoholism in adult and fetal livers, but not in fetal brains. Generally, levels of MDA were highest when both zinc deficiency and the ingestion of alcohol occurred concurrently. Glutathione (GSH) was depressed by zinc restriction in several adult and fetal tissues, but not in the fetal brain. Ethanol alone had no effect on GSH levels. The activity of the enzyme glutathione peroxidase (GSH-Px) was not changed in either organism by alcohol or zinc deficiency.Overall, the data point to increased lipid peroxidation in maternal and fetal rat tissues following zinc depletion and/or treatment with alcohol and draw attention to the apparent vulnerability of the fetal liver toin utero alcoholism. By contrast, the fetal brain seems to be especially resistant to alcohol and zinc-related lipoperoxidation. An association is suggested between the increased lipoperoxidation accompanying zinc deficiency and reduced levels of GSH, but this does not appear to relate to changes in the activity of GSH-Px. A similar relationship is not evident with respect to the increased levels of MDA in fetal and adult livers following chronic alcohol intoxication. A possible basis for the zinc-GSH interaction is discussed.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Dreosti IE,Partick EJdoi
10.1007/BF02795685subject
Has Abstractpub_date
1987-12-01 00:00:00pages
179-91issue
3eissn
0163-4984issn
1559-0720journal_volume
14pub_type
杂志文章abstract：:Adaptive alterations in glutathione (GSH) metabolism were studied during oxidative stress induced by selenium (Se) deficiency in germinating seedlings of Trigonella foenum-graecum grown for 72 h and the response to supplementation individually of Se or mimosine was explored. Growth enhancement with improved mitochondr...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783830
更新日期：1999-12-01 00:00:00
abstract：:In zinc deficiency, the function of leukocytes is impaired. However, the results of studies on the zinc concentration of blood cells in zinc deficiency are conflicting, probably in part because of technical and analytical problems. The aim of this study was to investigate, under standard conditions, the uptake of 65Zn...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783726
更新日期：1992-11-01 00:00:00
abstract：:Retraction to: Biol Trace Elem Res 144(1–3):1120–1132, DOI 10.1007/s12011-011-9149-z. Article has been retracted due to duplicate publication. ...
journal_title：Biological trace element research
pub_type： 撤回出版物
doi：10.1007/s12011-012-9550-2
更新日期：2013-01-01 00:00:00
abstract：:To elucidate compositional changes of the pubic symphysis (PS) by aging, elements of pubic symphysis (PSs) removed from 26 cadavers were determined by inductively coupled plasma atomic-emission spectrometry. It was found that the relative contents (RCs) of calcium and phosphorus in women's PSs were about three- and fi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783243
更新日期：1997-01-01 00:00:00
abstract：:The nuclear microscope is now gaining popularity in the field of life sciences. In particular, the combination of proton-induced X-ray emission to measure the elemental concentrations of inorganic elements, Rutherford backscattering spectrometry to characterize the organic matrix, and scanning transmission ion microsc...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/BF02784192
更新日期：1999-01-01 00:00:00
abstract：:Selenium-containing proteins in human serum of four volunteers in Beijing were separated and purified by preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Selenium contents in the proteins were quantified by high-performance liquid chromatography (HPLC) coupled with a fluorescence detec...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:100:2:105
更新日期：2004-08-01 00:00:00
abstract：:Numerous experiments in vitro and in vivo have shown that an appropriate increase intake of silicon can facilitate the synthesis of collagen and its stabilization and promote the differentiation and mineralization of osteoblasts. In this study, we examined whether ortho-silicic acid restrains the differentiation of os...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02286-6
更新日期：2020-07-16 00:00:00
abstract：:The present study investigated whether boron would enhance the action of 17beta-estradiol (E2) or parathyroid hormone (PTH) on bone mineral balance in ovariectomized (OVX) rats. Forty-three days after OVX, the rats were treated for 5 wk with vehicle, boron (5 ppm as boric acid), E2 (30 microg/kg/d, sc), PTH (60 microg...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:81:1:29
更新日期：2001-07-01 00:00:00
abstract：:Neutron activation analysis (NAA) methodology was applied for the certification of eight trace elements (As, Co, Cr, Cu, Hg, Mn, Se, and Zn) in a plankton reference material (CRM 414) prepared by the BCR of the Commission of the European Communities. Average concentrations (micrograms/g dry wt) and standard deviations...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917365
更新日期：1994-10-01 00:00:00
abstract：:Serum selenium levels were determined cross-sectionally in 57 HIV-infected patients who were classified according to the Centers for Disease Control (CDC) 1993 classification system. Mean serum selenium levels were lower in CDC stage II (58.7 +/- 12.2 micrograms/L; p < 0.01; n = 18) and stage III (47.6 +/- 11.3 microg...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02778982
更新日期：1997-01-01 00:00:00
abstract：:The present paper describes protective effects of supplemental selenium in mice infected with influenza virus. The effects of supplemental selenium on serum selenium levels, mortality, lung virus titers, and cytokine titers were investigated in mice inoculated intranasally with suspensions of influenza virus. Whereas ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8726-x
更新日期：2011-06-01 00:00:00
abstract：:Tibetan sheep have been observed with mineral deficiencies and marginal deficiencies in Qinghai-Tibetan Plateau. Adequate amounts of essential minerals are critical to maximize the productivity and health of livestock. The objectives of this study were to evaluate the effects of 6 months of mineral block supplementati...
journal_title：Biological trace element research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12011-015-0593-z
更新日期：2016-08-01 00:00:00
abstract：:Two experiments were performed to confirm that boron interacts with calcium, and that this interaction can be modified by dietary magnesium and potassium in the rat. Upon manipulating the dietary variables listed above, it was found that under certain conditions, boron and calcium deprivation similarly affected severa...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783768
更新日期：1992-12-01 00:00:00
abstract：:Although substantial progress has been achieved in inductovely coupled plasma (ICP) spectroscopy, placing it among the principal spectroscopic tools in analytical chemistry research and applications laboratories, some limitations exist especially for the analysis of ultratrace concentration levels in biological materi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02918324
更新日期：1984-02-01 00:00:00
abstract：:In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic) and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed that the formaldehyde inhalation caused gradual decline of body...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8686-1
更新日期：2011-05-01 00:00:00
abstract：:Chromium picolinate is used in the poultry diet because of its antistress effects in addition to the fact that the requirement for it is increased during stress. This study was conducted to determine if the negative effects of high ambient temperature (34 degrees C) on egg production, egg quality, antioxidant status, ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:101:2:181
更新日期：2004-11-01 00:00:00
abstract：:This study investigated the effects of ethanol (EtOH) on manganese (Mn)-induced striatal toxicity in rat by evaluating the neurobehavioral changes, biochemical and molecular events in rats exposed to Mn alone at 30 mg/kg, or their combination with EtOH at 1.25- and 5-g/kg body weight for 35 consecutive days. Locomotiv...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1587-4
更新日期：2019-09-01 00:00:00
abstract：:Preoperative diagnosis of papillary thyroid carcinoma (PTC) comprises numerous diagnostic procedures which are mostly applicable in tertiary institutions. Normal thyroid function depends on the presence of many trace elements and copper (Cu) and zinc (Zn) are some of those. The study is based on retrospective review o...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/s12011-014-0071-z
更新日期：2014-09-01 00:00:00
abstract：:X-ray Fluorescence (XRF) Analysis and Atomic Absorption Spectrophotometry (AAS) have been used in assessing heavy metal pollution from some gold mines in Ghana. The presence and levels of heavy metals in gold ore, gold tailings, inland waters, and river sediments have been determined. Using these techniques, the heavy...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02992682
更新日期：1990-07-01 00:00:00
abstract：:The aim of the present study was to investigate the effect of adding selenium (Se) in cereal production by fertilization on Se concentration in laying hen eggs. Tritordeum (×Tritordeum Ascherson et Graebner), a new cereal from the cross between durum wheat and a wild barley species having accreditation as natural crop...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0652-0
更新日期：2016-09-01 00:00:00
abstract：:Selenium deficiency is known to cause cardiovascular diseases. However, the role of Se deficiency in causing oxidative damage and inflammation injury to the aorta vessels of chickens is not well known. In the present study, 180 1-day-old chickens were randomly divided into two groups, a low-Se group (L group) and a co...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0676-5
更新日期：2016-10-01 00:00:00
abstract：:In present study, the levels of some toxic elements in 19 different home-made cosmetic products (spray hair dye, henna, tattoo, eyeliner, eye mascara, smear, lip moisturizer, and lipstick) were analyzed by inductively coupled plasma mass spectrometric (ICP-MS) after microwave digestion. The ICP-MS results were verifie...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02357-8
更新日期：2020-09-05 00:00:00
abstract：:Consumption of edible plants satisfies a significant part of human body needs in macro- and micronutrients while biologically active substances contain strong antioxidant properties and reduce the risk of a number of diseases. Balanced nutrition and design of personalized diets and treatment rely on the data on the co...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02345-y
更新日期：2020-08-19 00:00:00
abstract：:Six important metal contents (i.e., zinc, barium, magnesium, calcium, copper, and selenium) in blood samples coupled with an ensemble classification algorithm have been used for the classification of normal people and cancer patients. A dataset containing 42 healthy samples and 32 cancer samples was used for experimen...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8864-1
更新日期：2011-10-01 00:00:00
abstract：:This comparative study of the intestinal absorption of four toxic metals (aluminum, manganese, nickel, and lead) carried out in rats using the in situ intestinal perfusion technique was able to measure the partition of each metal between the intestine (intestinal retention), the blood circulation, and target tissues a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:99:1-3:157
更新日期：2004-07-01 00:00:00
abstract：:Injectable trace minerals (ITMs) could provide a potential alternative way of trace mineral delivery for sick animals. Therefore, evaluation of ameliorative potentials of ITMs (copper, manganese, selenium, and zinc) on the circulating Th1/Th2 cytokine misbalance in Theileria annulata-infected calves was aimed. Forty-t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02263-z
更新日期：2020-06-22 00:00:00
abstract：:The element Zn is the metal component or activator of many important enzymes. The tissue concentrations and activities of Zn metalloenzymes direct the rate of protein and nucleic acid syntheses, thereby influencing tissue growth and reperative processes. Most of the serum Zn is normally bound to circulating proteins. ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02786257
更新日期：1996-08-01 00:00:00
abstract：:In order to understand the normal and pathological physiologies of the epidermal cells, the simultaneous determination of several elements in the different cellular strata is of crucial importance. In recent years the electron microprobe (EMP) has become an established technique in this field. Its high spatial resolut...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02796687
更新日期：1987-04-01 00:00:00
abstract：:Lipid peroxy radicals (ROO.) were detected by electron spin resonance (ESR) at low temperature after formation by addition of H2O2 into a suspension of mice lymphocytes. If lymphocytes were treated with selenomethionine (Se-Met) prior to addition of H2O2, ROO. formation was inhibited in a fashion that was dependent on...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783233
更新日期：1997-01-01 00:00:00
abstract：:Zinc is a nutritionally essential trace element required for many biological functions to be successfully carried out. The aim of the present work was to study the influence of zinc on the intestinal absorption of L-threonine and on the aminopeptidase N activity in rabbit jejunum, after in vitro addition and/or oral a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784557
更新日期：1996-07-01 00:00:00
