Abstract:
:Injectable trace minerals (ITMs) could provide a potential alternative way of trace mineral delivery for sick animals. Therefore, evaluation of ameliorative potentials of ITMs (copper, manganese, selenium, and zinc) on the circulating Th1/Th2 cytokine misbalance in Theileria annulata-infected calves was aimed. Forty-three T. annulata-infected newborn calves were randomly allocated into four groups: buparvaquone alone-treated group (BUPA), buparvaquone + oxytetracycline (BUPA + OXY)-treated group, buparvaquone + injectable trace minerals (BUPA + ITMs)-treated group, and BUPA + OXY + ITM-treated group. Blood samples were collected from each of the calves before the start of therapy (day 0) and on day 14 post-therapy. Serum contents of pro- and anti-inflammatory cytokines were estimated by bovine specific ELISA kits. On day 14 post-therapy, significant amelioration in the circulating levels of the studied cytokines was not observed in the calves treated with BUPA, while the calves treated with BUPA + OXY revealed significant (P ≤ 0.04) amelioration in the circulating tumour necrosis factor-α (TNF-α) level. The calves treated with BUPA + ITMs revealed significant (P ≤ 0.041) elevation in the circulating interferon-γ (IFN-γ) and significant (P ≤ 0.011) reduction in the interleukin-10 (IL-10) levels. Moreover, the calves treated with BUPA + OXY + ITMs revealed significant reduction in TNF-α (P ≤ 0.0001) and IL-10 (P ≤ 0.012) contents, and significant elevation in IFN-γ (P ≤ 0.0002) content on day 14 post-therapy. None of the treated calve group revealed significant alteration in the circulating level of transforming growth factor-β (TGF-β) on day 14 post-therapy. In conclusion, administration of ITMs to the therapeutic regimen of newborn calves with tropical theileriosis could be a promising therapeutic strategy. ITMs can be recommended for the amelioration of immunological misbalance due to tropical theileriosis in newborn calves.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Ram PK,Singh SK,Srivastava A,Kumar G,Jaiswal AK,Yadav B,Garg SKdoi
10.1007/s12011-020-02263-zsubject
Has Abstractpub_date
2020-06-22 00:00:00eissn
0163-4984issn
1559-0720pii
10.1007/s12011-020-02263-zpub_type
杂志文章abstract::The aim of this study was to examine the effects of cadmium in concentrations relevant to those detected in human serum on cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) expression at mRNA, protein, and enzyme activity levels in THP-1 macrophages. Macrophages were incubated with various cadmium chloride (CdCl2)...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0234-6
更新日期:2015-06-01 00:00:00
abstract::The present study aimed to evaluate the effect of fluoride (F) on spermatogenesis in male rats. F- at 50 and 100 mg/L was administered for 70 days, after which the testicular and epididymis tissues were collected to observe the histopathological structure under a light microscope. The ultrastructure of the testis and ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1338-6
更新日期:2018-12-01 00:00:00
abstract::Retraction to: Biol Trace Elem Res 144(1–3):1120–1132, DOI 10.1007/s12011-011-9149-z. Article has been retracted due to duplicate publication. ...
journal_title:Biological trace element research
pub_type: 撤回出版物
doi:10.1007/s12011-012-9550-2
更新日期:2013-01-01 00:00:00
abstract::A study was conducted to determine the effect of dietary selenium (Se) concentration and source for broiler chickens on performance, nutrient digestibility, plasma Se, glutathione peroxidase (GPx) activity, and thiobarbituric acid reactive substances (TBARS). A total of 700 1-day-old broiler chicks were assigned to 7 ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01801-8
更新日期:2020-04-01 00:00:00
abstract::The Nord-Trøndelag Health Study (The HUNT Study) is a large health survey population study in the county of Trøndelag, Norway. The survey has been repeated four times in about 10-year intervals. In the HUNT3 survey (2006-2008), we collected 28,000 samples for trace element analysis. Blood samples from 758 healthy pers...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02376-5
更新日期:2020-09-08 00:00:00
abstract::The primary objective of the present study is analysis of hair trace elements content in children with communication disorder (CD) and autism spectrum disorder (ASD). A total of 99 children from control, CD, and ASD groups (n = 33) were examined. All children were additionally divided into two subgroups according to a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0878-x
更新日期:2017-06-01 00:00:00
abstract::The purpose of this study was to determine glutathione peroxidase (GSHPx) activity in the liver of red deer in relation to selenium concentrations in the liver, as well as to evaluate changes in GSHPx activity according to sex, body weight and season of the year. Total selenium concentration in the liver of red deer a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9022-0
更新日期:2011-12-01 00:00:00
abstract::Manganese (Mn) is essential for several species and daily requirements are commonly met by an adequate diet. Mn overload may cause motor and psychiatric disturbances and may arise from an impaired or not fully developed excretion system, transporter malfunction and/or exposure to excessive levels of Mn. Therefore, dec...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1531-7
更新日期:2019-03-01 00:00:00
abstract::Wild barley (Hordeum spontaneum), the progenitor of cultivated barley, is an important genetic resource for cereal improvement. Selenium (Se) is an essential trace mineral for humans and animals with antioxidant, anticancer, antiarthropathy, and antiviral effects. In the current study, the grain Se concentration (GSeC...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8770-6
更新日期:2011-09-01 00:00:00
abstract::The catalytic activity of cerium oxide nanoparticles (CeO2NPs) is responsible for its application as an antitumor agent. This activity may be due to its ability to switch between III and IV oxidation states thereby conferring pro- and antioxidant properties. This study was designed to assess the hepatoprotective poten...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01696-5
更新日期:2020-01-01 00:00:00
abstract::Although adriamycin (ADR) exhibits high anti-tumor efficacy in vitro, its clinical use in cancer chemotherapy is limited due to its high renal toxicity. This study investigated the mechanism of ADR nephropathy and the protective effect of selenium on ADR-induced kidney damage by analyzing of the relationship between s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9273-9
更新日期:2012-06-01 00:00:00
abstract::Inducing the differentiation of stem cells from human exfoliated deciduous teeth (SHEDs) proceeds with low efficiency, which greatly limits clinical applications. Divalent metal elements play an important role in osteoinductivity for bone remodeling because they can simulate bone formation and decrease bone resorption...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1256-7
更新日期:2018-10-01 00:00:00
abstract::In this study, the amount of reduced glutathione (GSH), oxidized glutathione (GSSG), and malondialdehyde (MDA) were determined by high performance liquid chromatography (HPLC), and selenium was determined by using the fluorescence spectrophotometer in eight different species of edible mushrooms. Brittlegill mushroom (...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0715-2
更新日期:2016-12-01 00:00:00
abstract::Zinc (Zn) is an essential nutrient that is required in humans and animals for many physiological functions, including immune and antioxidant function, growth, and reproduction. The present study was performed to investigate the effects of three Zn levels, including Zn adequate (35.94 mg/kg, as a control), Zn deficienc...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:107:2:153
更新日期:2005-11-01 00:00:00
abstract::This meta-analysis was conducted aiming to summarize the results obtained from the previous studies so that the effect of opium on blood lead levels (BLLs) can be investigated. Scopus, Embase, PubMed, and Web of Science (ISI) were systematically searched up to June 2020. Heterogeneity of the included studies was evalu...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02504-1
更新日期:2020-11-26 00:00:00
abstract::To elucidate compositional changes of the cardiac walls with development and aging, the authors investigated changes of elements in the atrial and ventricular walls of monkeys. The left and right atrial walls, left and right ventricular walls, and interatrial and interventricular septa were resected from the subjects....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:110:3:233
更新日期:2006-06-01 00:00:00
abstract::The present study investigated the interactive effects of copper sources and a high level of phytase on growth performance, nutrient digestibility, tissue mineral concentrations, and plasma parameters in nursery pigs. Weaning piglets (N = 192; 6.06 ± 0.99 kg), blocked by body weight, were randomly allotted to 1 of 4 d...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-021-02580-x
更新日期:2021-01-11 00:00:00
abstract::Analysis of variance, analysis of covariance, correlation coefficient, multiple correlation, and partial correlation coefficient statistical tests were applied to Cs, Cr, Co, Fe, Rb, Sc, Se, and Zn content in human ovaries in order to evaluate statistically the possible relationships between these trace elements at: t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784090
更新日期:1996-04-01 00:00:00
abstract::Cadmium (Cd) exposure has been recognized to result in a wide variety of cellular responses, including oxidative stress and body weight loss. The aim of the present study was to examine the effect of lycopene supplementation on the antioxidant defense system, lipid peroxidation (LPO) level, nitric oxide (NO), tumor ne...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-0027-7
更新日期:2007-08-01 00:00:00
abstract::The effects of 10 wk of selenium (Se) supplementation (5 ppm) in drinking water on immune responses and resistance to a myocarditic Coxsackie virus B3 (CB3) infection were studied in female Balb/c mice. Se supplementation reduced CB3-induced mortality: at day 14 postinoculation, survival was 58% in the Se-treated grou...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785277
更新日期:1998-07-01 00:00:00
abstract::Manganese (Mn) is an essential nutrient for both host and pathogen. Recent studies have demonstrated the nutritional immunity of Mn against Salmonella infection in mammals. To investigate the effect of high dietary Mn on immune responses of broilers following Salmonella challenge, 144 1-day-old male broilers were fed ...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-017-1060-9
更新日期:2018-02-01 00:00:00
abstract::This study was initiated to examine if variations in the concentrations of cadmium (Cd) and lead (Pb) in water environment may affect metal levels in local foods and body burden of local residents in non-polluted areas in Japan. Two nationwide databases have been made available on concentrations of Cd in locally harve...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8436-4
更新日期:2010-03-01 00:00:00
abstract::In order to study the metabolism of mercury (Hg), its affinity to metallothionein (MT), and its influence on levels of the essential metals copper and zinc in the brain tissue of rats exposed to elemental mercury (HgO) vapor was investigated. The major findings were: 1. After long-term exposure, about 40% of mercury w...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789402
更新日期:1993-04-01 00:00:00
abstract::A simple, quick procedure has been developed for preparation of human lenses for total chromium (Cr) analysis by electrothermal atomic absorption spectrometry (EAAS). This procedure involves wet ashing in a mini-autoclave with HNO3 and H2SO4. Recovery was 101.6%. This procedure is simple to carry out, does not generat...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784598
更新日期:1992-01-01 00:00:00
abstract::Selenium is a trace element that, although toxic in higher concentrations, is essential for human and animal health. In this study, we looked at microarray-based gene expression patterns from liver and gastrocnemius tissues in mice fed either a selenium-deficient diet or diets containing sodium selenite, selenomethion...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8894-8
更新日期:2011-11-01 00:00:00
abstract::Recent publications in Japan suggest that Cd in river beds and locally harvested rice tend to be higher in seven prefectures in the north-eastern part on the coast of the Sea of Japan (the high-Cd zone). The present study was initiated to investigate the current level of exposure to Cd and possible health effects amon...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8646-9
更新日期:2011-02-01 00:00:00
abstract::Copper is an essential trace element with various biological functions. Excess copper, however, is extremely toxic, leading to many pathological conditions that are consistent with oxidative damage to membranes and molecules. Exposure to high levels of copper results in various changes in the tissues. In liver, hypert...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:96:1-3:209
更新日期:2003-01-01 00:00:00
abstract::Zinc absorption from the alimentary tract, as revealed by serum zinc concentration, was studied in a group of 10 patients (age 37.7+/-5.1 yr) with moderate and severe untreated primary arterial hypertension before and after a 30-d treatment with perindopril 4 mg/d. Blood pressure was 177.33+/-16.24/111.33+/-15.26 mm H...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:83:1:31
更新日期:2001-10-01 00:00:00
abstract::The purpose of this study was to analyze the existing studies and to investigate the relationship between children's full-scale intelligence quotient (FIQ), verbal IQ (VIQ), and performance IQ (PIQ) and their blood lead (Pb) and zinc (Zn) levels. All documents in Chinese and English were collected from the PubMed, Web...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s12011-017-1093-0
更新日期:2018-04-01 00:00:00
abstract::To elucidate compositional changes of peripheral nerves with aging, the authors investigated age-related changes of elements and their relationships in the optic, trigeminal, vagus, median, radial, ulnar, femoral, sciatic, tibial, and common peroneal nerves by inductively coupled plasma-atomic emission spectrometry. T...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:98:3:229
更新日期:2004-06-01 00:00:00