Abstract:
:The purpose of this study was to analyze the existing studies and to investigate the relationship between children's full-scale intelligence quotient (FIQ), verbal IQ (VIQ), and performance IQ (PIQ) and their blood lead (Pb) and zinc (Zn) levels. All documents in Chinese and English were collected from the PubMed, Web of Science, and Chinese National Knowledge Infrastructure (CNKI) databases from inception date to December 30, 2016. RevMan software (version 5.2) was used for the meta-analysis and Stata software (version 12.0) for the meta-regression and sensitivity analyses. A total of 32 eligible literatures was included in the study. Seven prevalence studies showed that the blood Pb level was negatively correlated with children's IQ. The results of the meta-analysis from 22 case-control studies indicate a significant difference between FIQ and PIQ with blood Pb levels, detailed as the FIQ score with a weighted mean difference (WMD) = -6.60 (95% CI: -9.01, -4.20), P < 0.001; PIQ WMD = -8.85 (95% CI: -12.651, -5.05), P < 0.001; but VIQ WMD = -3.32 (95% CI: -6.98, 0.33), P > 0.05. Three studies on the blood Zn concentrations were with a FIQ WMD = 7.88 (95% CI: -0.07, 15.83), VIQ WMD = 7.73 (95% CI: -7.40, 22.86), and PIQ WMD = 6.69 (95% CI: -7.13, 20.51), all P > 0.05. The results indicate that Pb is harmful to children's intelligence development, especially in PIQ. Zn is beneficial to intelligence, although more studies are needed.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Wu Y,Sun J,Wang M,Yu G,Yu L,Wang Cdoi
10.1007/s12011-017-1093-0subject
Has Abstractpub_date
2018-04-01 00:00:00pages
185-195issue
2eissn
0163-4984issn
1559-0720pii
10.1007/s12011-017-1093-0journal_volume
182pub_type
杂志文章,meta分析,评审abstract::Aluminum (Al) absorption seems to be very low, but many factors can enhance it in animals and humans. In the present study, we investigated the acute effect of Na citrate on Al absorption by monitoring Al levels in blood and several tissues. For this purpose, 18 Wistar male rats were divided into 3 groups: control, Al...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02778873
更新日期:1998-08-01 00:00:00
abstract::Water-borne arsenicosis is caused by the consumption of excess levels of inorganic arsenic from drinking water and is a worldwide public health issue. Arsenic exposure has recently attracted extensive attention due to its damage to the cardiovascular system. Vascular endothelial dysfunction (VED) is recognized as an i...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1559-8
更新日期:2019-08-01 00:00:00
abstract::Interactions of clinical laboratory parameters with trace elements in knee-joint effusions might turn out to be potential diagnostic tool, increasing our pathophysiological understanding and knowledge on knee-joint effusions. Thus, the 11 clinical laboratory parameters, total protein, albumin, glucose, lactate dehydro...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:79:2:139
更新日期:2001-02-01 00:00:00
abstract::Aflatoxin B1 (AFB1) is the most toxic among the mycotoxins and causes detrimental health effects on the liver of human and animals. Selenium (Se) plays an important role in protection of various animal species against numerous notorious toxic agents. The present study is designed to explore the protective effects of S...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1623-4
更新日期:2019-10-01 00:00:00
abstract::Electron energy loss spectroscopy (EELS) is a high spatial resolution electron microscopic technique with the potential to quantify elements at the subcellular level. The presence of each element is demonstrated by the electron energy loss edge at the energy characteristic of that element. The area of the edge may ind...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916819
更新日期:1994-01-01 00:00:00
abstract::Interaction of elements in the course of element uptake by carrot (Daucas carota cv. U.S. harumakigosun) exerted by the addition of elements, such as Rb, Zn, and Al, was investigated. For the purpose of precise evaluation of uptake behavior, the simultaneous determination of absorption of Na, Be, Sr, Mn, Co, Zn, Ce, P...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:84:1-3:197
更新日期:2001-01-01 00:00:00
abstract::The concentrations of elements in urine obtained from cats with urolithiasis were compared with those of healthy cats. The concentration of several elements, such as sodium (Na), phosphorus (P), sulfur (S), and potassium (K), in urine obtained from cats with urolithiasis was significantly higher than that of healthy c...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8893-9
更新日期:2011-11-01 00:00:00
abstract::The trace elements antimony, bromine, cesium, cobalt, iron, rubidium, scandium, strontium and zinc were determined by instrumental neutron activation analysis in breast tissue samples with fibrocystic disease and in samples with fibroadenoma tumors. The histological lesions of each breast sample with fibrocystic disea...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917337
更新日期:1994-10-01 00:00:00
abstract::The objective of this paper is to investigate the correlation between serum macro-element and trace element contents and bone mineral density (BMD) as well as the occurrence of osteoporosis. After the epidemiological investigation of 290 postmenopausal women from ages 45 to 65 in the Xi'an urban area, their blood was ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8363-4
更新日期:2009-12-01 00:00:00
abstract::Obesity, a chronic inflammatory state, is associated with altered zinc metabolism. ZnT and Zip transporters are involved in the regulation of zinc metabolism. This study examined the relationships among obesity, zinc transporter gene expression, and inflammatory markers in young Korean women. The messenger RNA (mRNA) ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9902-1
更新日期:2014-04-01 00:00:00
abstract::Trace element contamination in Chinese herbal medicines has been recognized as a potential health concern for consumers. To assess the health risk to the herb-consuming population, nine trace elements (Cu, Cd, Cr, Mo, Ni, Pb, Sr, Zn, and As) were investigated based on their concentrations in three common medicinal pla...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02539-4
更新日期:2021-01-03 00:00:00
abstract::Selenium is a trace element that has antioxidant and neuroprotective effects. The aim of this study is to investigate the effects of selenium in reducing ischemia-reperfusion injury of the gastrocnemius muscle. In this experimental study, 80 adult male Wistar rats weighing 250-300 g were divided into ten groups (N = 8...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0218-y
更新日期:2015-04-01 00:00:00
abstract::Selenium was added to the feed of White Leghorn type chickens 1 day prior to challenge with either Escherichia coli or sheep erythrocyte antigen. The incidence of death or lesions was reduced from 86% to 21% at the optimal dose of selenium (0.4 mg/kg resulting in feed concentration of 0.45 mg/kg). After the chickens w...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917469
更新日期:1997-09-01 00:00:00
abstract::The effects of environmental lead on the immune system of young children were assessed by determining the peripheral blood lymphocytes CD3+, CD4+, CD8+, B(CD19+) counts, and natural killer (CD16+CD56+) cells in 35 preschool children whose mean blood lead level was 140.6 microg/L. The results were compared to an age- a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:105:1-3:019
更新日期:2005-07-01 00:00:00
abstract::The efficacy of selenate and other divalent anions to stimulate the efflux of radiolabeled sulfate from lactating rat mammary tissue slices has been examined. Both selenate and sulfate markedly increased the fractional release of sulfate via a system that is temperature-sensitive and sensitive to the anion-exchange in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917205
更新日期:1990-03-01 00:00:00
abstract::The aim of this study was to investigate the possible protective role of selenium and L-carnitine on oxidative stress induced by 2.45-GHz radiation in heart of rat. For this purpose, 30 male Wistar Albino rats were equally divided into five groups namely controls, sham controls, radiation-exposed rats, radiation-expos...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-8994-0
更新日期:2011-12-01 00:00:00
abstract::Normal and uremic adult male rats were given a daily ip injection of 20 mg Al (Al chloride)/kg for 14 d. The results indicate that Al induces a significant decrease in food ingestion, weight gain, and total protein concentration in the plasma. Compared with control animals, very high increases in Al levels were found ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785319
更新日期:1996-07-01 00:00:00
abstract::Endemic waterborne fluorosis is a public health problem in Isparta, a city located in southern Turkey. Fluoride is a cumulative element that increases metabolic turnover of the bone and also affects the homeostasis of bone mineral metabolism. There are number of similarities between the effects of excess parathyroid h...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8847-2
更新日期:2011-10-01 00:00:00
abstract::We explored the synergistic effect of serine combined with several selenocompounds or used alone on the expression of selenoprotein P (SelP) and glutathione peroxidase (GPx) in this study. We first compared the SelP and GPx expression difference between HepG2 and Hela cells treated with serine and finally chose HepG2 ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0665-8
更新日期:2016-10-01 00:00:00
abstract::We investigated the effect of magnesium supplementation on zinc distribution in rats given excess calcium as carbonate. Rats were given a control diet (5 g/kg calcium and 0.5 g/kg magnesium), a high calcium diet (HC, 25 g/kg calcium and 0.5 g/kg magnesium) or the high calcium diet supplied with magnesium (HCM, 25 g/kg...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8166-z
更新日期:2008-11-01 00:00:00
abstract::Quercetin, a plant-derived flavonoid, is frequently used as an antioxidant for efficient anti-oxidative capacity. However, whether quercetin has protective effects on goat sperm and preimplantation embryos against Cd2+-induced oxidative injury is still unclear. So, we researched the influence of quercetin on goat sper...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1255-8
更新日期:2018-10-01 00:00:00
abstract::Heavy metals toxicity is a prevalent health problem particularly in developing countries. Mercury and cadmium are toxic elements that have no physiologic functions in human body. They should not be present in the human body by any concentration. Copper, on the other hand, is one of the elements that are essential for ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0525-y
更新日期:2016-06-01 00:00:00
abstract::To examine whether the calcium accumulation in the arteries is related to the way of walk or not, the calcium contents were determined in various arteries of Japanese monkeys of quadrupedal walk by inductively coupled plasma-atomic emission spectrometry. Japanese monkeys consisted of five males and four females, rangi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:82:1-3:077
更新日期:2001-07-01 00:00:00
abstract::One hundred and eighty Kunming mice were allotted to three groups in a randomized complete block design, including two treatments and one control. Mice in group 1 were fed a basal diet as control, while mice in groups 2 and 3 were fed the basal diet supplemented with 0.2 mg/kg selenium as sodium selenite (SS) or selen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0243-5
更新日期:2015-06-01 00:00:00
abstract::Antagonistic interactions between silicon and aluminum occur in living organisms. Thus, an experiment was performed to ascertain whether high dietary aluminum would accentuate the signs of silicon deprivation in rats and conversely whether silicon deprivation would accentuate the response to high dietary aluminum. The...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917430
更新日期:1994-06-01 00:00:00
abstract::Lipid disturbance induced by high-fat diet is a worldwide problem, and it can induce inflammation and oxidative stress in vivo. Zinc is considered as an antioxidant, anti-inflammatory agent. Since matrix metalloprotease 2 (MMP2) and matrix metalloprotease 9 (MMP9)'s expressions are changed under many pathological cond...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0367-7
更新日期:2015-12-01 00:00:00
abstract::Hypomagnesemia is associated with the development of neuropathy and abnormal platelet activity, both of which are risk factors for diabetic foot ulcer (DFU). This study was carried out to evaluate the effects of magnesium administration on wound healing and metabolic status in subjects with DFU. This randomized, doubl...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-017-1056-5
更新日期:2018-02-01 00:00:00
abstract::Adaptive alterations in glutathione (GSH) metabolism were studied during oxidative stress induced by selenium (Se) deficiency in germinating seedlings of Trigonella foenum-graecum grown for 72 h and the response to supplementation individually of Se or mimosine was explored. Growth enhancement with improved mitochondr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783830
更新日期:1999-12-01 00:00:00
abstract::The decline in fish population because of water contamination is problem. As a result of direct exposure in water, it has been readily accepted that the gills are the main site of water contamination and toxicity (e.g., metal ions). In the present study, we investigated metal ion contamination on the functional capaci...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:100:3:229
更新日期:2004-09-01 00:00:00
abstract::We hypothesized that blood heavy metal levels such as lead, cadmium, and mercury were associated with uric acid level and hyperuricemia, and that this association remains significant after adjustment for other metals. We tested this hypothesis using the Korean National Health and Nutrition Examination Survey data. Bet...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02152-5
更新日期:2021-01-01 00:00:00