Abstract:
:Zinc absorption from the alimentary tract, as revealed by serum zinc concentration, was studied in a group of 10 patients (age 37.7+/-5.1 yr) with moderate and severe untreated primary arterial hypertension before and after a 30-d treatment with perindopril 4 mg/d. Blood pressure was 177.33+/-16.24/111.33+/-15.26 mm Hg before and 143.41+/-17.34/91.29+/-12.54 mm Hg after treatment (p < 0.05/p < 0.05). Nine persons (age 37+/-6.2 yr) with normal blood pressure (121.33+/-9.9/78+/-5.23 mm Hg) were the control group. Blood samples were taken from the ulnar vein at 8.00 AM (0 h), before taking zinc orally (one tablet of Zincas (zinc aspartate), containing 5 mg Zn2+) and at 1, 3, and 6 h after the dose. Serum zinc concentration in control and hypertensive group (before treatment) were initially 15.47+/-6.26 versus 15.99+/-5.65 (NS), 19.37+/-6.40 versus 20.83+/-4.48 (NS) after 1 h, 17.91+/-4.76 versus 31.32+/-10.49 (p < 0.003) after 3 h, and 15.32+/-5.47 versus 17.87+/-6.56 (NS) after 6 h. Maximal increase of Zn was 4.77+/-2.10 versus 17.53+/-4.13, respectively (p < 0.001). In the hypertensive group, serum Zn before and after perindopril treatment was initially 15.98+/-5.65 versus 14.81+/-3.11 (NS), 20.83+/-4.48 versus 18.17+/-2.50 (NS) after 1 h, 31.32+/-10.49 versus 22.94+/-5.80 (NS) after 3 h, 17.53+/-4.13 (p < 0.001) after 6 h. Maximal increase of Zn before treatment was 17.53+/-4.13 versus 9.17+/-4.67 (p < 0.017) after treatment. The following conclusions were reached: (1) In patients with primary arterial hypertension, an increased zinc absorption from alimentary tract was found; (2) A 30-d perindopril treatment 4 mg/d orally decreased zinc absorption in these patients.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Tubek Sdoi
10.1385/BTER:83:1:31subject
Has Abstractpub_date
2001-10-01 00:00:00pages
31-8issue
1eissn
0163-4984issn
1559-0720pii
BTER:83:1:31journal_volume
83pub_type
杂志文章abstract::Nutritional profile of minerals and antioxidants in Indian spice extracts was evaluated in order to examine their efficacy in treating various diseases, disorders, and allergies in human health. Extracts of four medicinal plants such as Curcuma longa, Zingiber officinale, Piper nigrum, and Piper longum, regularly cons...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02228-2
更新日期:2021-03-01 00:00:00
abstract::The developmental alterations in metallothionein (MT) proteins and zinc (Zn) were investigated in brains of two transgenic strains of mice. MT protein was measured by a cadmium binding assay and Zn by atomic absorption spectrophotometry. MT proteins were expressed at birth (day 1) both in MT-I overexpressing transgeni...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784039
更新日期:1998-01-01 00:00:00
abstract::The aim of this study was to trace zinc nanocrystals in the anterior pituitary of zinc-deficient Wistar rats by using autometallographic technique. Male Wistar rats (30-40 days of age, pre-pubertal period) of 40-50 g body weight were divided into the following: the ZC (zinc control) group-fed with 100 ppm zinc in diet...
journal_title:Biological trace element research
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doi:10.1007/s12011-016-0881-2
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abstract::The levels of iron, zinc, and copper in the tissues of the pregnant rat, on d 12, 19, and 21 after impregnation have been determined and compared with controls. Iron levels decreased considerably in late pregnancy as a result of increased fetal requirements, thus diminishing iron stores in rat tissues, but maintaining...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917464
更新日期:1985-09-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9061-6
更新日期:2011-12-01 00:00:00
abstract::Nowadays, 70 % of global monogastric feeds contains an exogenous phytase. Phytase supplementation has enabled a more efficient utilisation of phytate phosphorous (P) and reduction of P pollution. Trace minerals, such as iron (Fe), zinc (Zn), copper (Cu) and manganese (Mn) are essential for maintaining health and immun...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0161-y
更新日期:2015-02-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:2007-07-01 00:00:00
abstract::Previous studies showed the attenuation of both morphine-dependence and morphine-place preference by zinc. Conditioned place preference and aversion are experimental models frequently used to test the reward-stimulating, respectively the aversive effects induced by different stimuli or substances. Addictive substances...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-0995-1
更新日期:2017-11-01 00:00:00
abstract::The objective of this study was to determine the effect of systemic MgSO4 infusion on subendocardial and subepicardial perfusion. Seventeen spontaneously breathing piglets were examined. Myocardial perfusion was measured using radiolabeled microspheres at baseline, 30 and 60 min after either MgSO4 (80 mg/kg) or saline...
journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:1997-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8625-1
更新日期:2010-12-01 00:00:00
abstract::The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0477-2
更新日期:2016-04-01 00:00:00
abstract::The phosphorus NMR profile of normal and vanadium-treated chick muscle was obtained in vivo. The data show that the differentiation of breast and thigh muscles in terms of pH, lipid related metabolites, and bioenergetic parameters can be readily followed. Although the vanadium-treated chicks showed substantial retarda...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990427
更新日期:1991-11-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917499
更新日期:1988-12-01 00:00:00
abstract::No specific treatment for COVID-19 infection is available up till now, and there is a great urge for effective treatment to reduce morbidity and mortality during this pandemic. We aimed to evaluate the effect of combining chloroquine/hydroxychloroquine (CQ/HCQ) and zinc in the treatment of COVID-19 patients. This was ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02512-1
更新日期:2020-11-27 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917223
更新日期:1994-04-01 00:00:00
abstract::Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. A cross-sect...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1154-4
更新日期:2018-06-01 00:00:00
abstract::In order to study the mechanisms underlying the effects of TiO(2) nanoparticles on lactate dehydrogenase (LDH, EC1.1.1.27), Institute of Cancer Research region mice were injected with nanoparticulate anatase TiO(2) (5 nm) of various doses into the abdominal cavity daily for 14 days. We then examined LDH activity in vi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8548-x
更新日期:2010-09-01 00:00:00
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journal_title:Biological trace element research
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-09-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917365
更新日期:1994-10-01 00:00:00
abstract::Garlic (Allium sativum) is known to reduce lead toxicity in some species of animals. The objective of this study was to evaluate the efficacy of allicin, one of the most active components of garlic, in the treatment of subacute lead intoxication in sheep. Nine female sheep weighing 25-29 kg orally received a daily dos...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8185-9
更新日期:2008-01-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783342
更新日期:1998-07-01 00:00:00
abstract::Biominerals and metals of intertidal corals of two species (Heliofungia actiniformis, Quoy and Gaimard; Galaxea fascicularis, Linnaeus), collected from the Iriomote Island of Ryukyu, were examined with an inductively coupled plasma atomic emission spectrometer (ICP-AES). Twelve elements were detectable in the corallin...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784268
更新日期:1998-11-01 00:00:00
abstract::The aim of this study was to assess the effect of sibutramine on mineral status and selected biochemical parameters in obese women. The study was conducted on 24 patients who received 15 mg daily doses of sibutramine for 12 weeks, and on 20 patients who received placebo. At the baseline, after the sixth and twelfth we...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9425-6
更新日期:2012-11-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0354-z
更新日期:2015-11-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784242
更新日期:1999-01-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:88:3:203
更新日期:2002-09-01 00:00:00
abstract::The incorporation of(3)H-thymidine into DNA in the brains of the 17-day and 20-day old rat fetuses was significantly reduced by maternal zinc restriction during pregnancy. The activity of the enzyme thymidine kinase (EC 2.7.1.21) was similarly reduced in the zine-deprived fetal brains on days 14 and 20 of gestation, b...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789032
更新日期:1980-03-01 00:00:00