Abstract：
:The developmental alterations in metallothionein (MT) proteins and zinc (Zn) were investigated in brains of two transgenic strains of mice. MT protein was measured by a cadmium binding assay and Zn by atomic absorption spectrophotometry. MT proteins were expressed at birth (day 1) both in MT-I overexpressing transgenic mouse (MT-I*) and MT-null (expressing only brain specific isoform, MT-III) transgenic mouse. MT proteins level (mainly MT-I) in MT-I* was 16.1 microg/g at birth, and thereafter increased with age to a maximal adult level of 55.3 microg/g (day 60). Zn level in MT-I* also increased from 8.43 microg/g (day 1) to 20.7 microg/g (day 60) with age. MT protein (MT-III) in MT-null mouse was 9.71 microg/g at birth and remained relatively unchanged during development. Zn level in MT-null mouse at birth was 9.46 microg/g and also remained unchanged during development. The similar alterations in MT isoforms and Zn in brain during development suggest that MT isoforms may act as a Zn binding protein.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Ono SI,Cherian MGdoi
10.1007/BF02784039subject
Has Abstractpub_date
1998-01-01 00:00:00pages
41-9issue
1eissn
0163-4984issn
1559-0720journal_volume
61pub_type
杂志文章abstract：:Biominerals and metals of intertidal corals of two species (Heliofungia actiniformis, Quoy and Gaimard; Galaxea fascicularis, Linnaeus), collected from the Iriomote Island of Ryukyu, were examined with an inductively coupled plasma atomic emission spectrometer (ICP-AES). Twelve elements were detectable in the corallin...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784268
更新日期：1998-11-01 00:00:00
abstract：:Zinc is an essential micronutrient for the organism and is critical for the functional and structural integrity of cells. Determination of the amount of trace element concentrations in tissues such as hair samples have been used for the evaluation of the metabolic status especially in children. Unlike serum zinc, conc...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02115-w
更新日期：2020-08-01 00:00:00
abstract：:To elucidate the action of the myocardial bridge (MB) on the coronary artery, the authors first prepared the hearts with the MB located in the middle one third of the left anterior descending (LAD) artery and then investigated element accumulation in the LAD artery of the hearts with the MB by direct chemical analysis...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0498-x
更新日期：2016-05-01 00:00:00
abstract：:Plasma zinc (Zn) concentrations were measured in 4376 indigent women (86% African-American), at at mean (+/- SD) gestational age of 15 (+/- 7.8) wk to determine the relationship between various maternal characteristics and plasma Zn levels during pregnancy. Mean Plasma An levels were lower in African-American women th...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784174
更新日期：1996-10-01 00:00:00
abstract：:Obesity, a chronic inflammatory state, is associated with altered zinc metabolism. ZnT and Zip transporters are involved in the regulation of zinc metabolism. This study examined the relationships among obesity, zinc transporter gene expression, and inflammatory markers in young Korean women. The messenger RNA (mRNA) ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-9902-1
更新日期：2014-04-01 00:00:00
abstract：:Calsyntenin-2 (Clstn2) and calsyntenin-3 (Clstn3) are the members of the cadherin superfamily and function to regulate the postsynaptic activity. Both proteins are known to play an important role in memory and learning. This study was designed to test the hypothesis that exposure of mothers to Pb in drinking water may...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02241-5
更新日期：2020-06-16 00:00:00
abstract：:Water-borne arsenicosis is caused by the consumption of excess levels of inorganic arsenic from drinking water and is a worldwide public health issue. Arsenic exposure has recently attracted extensive attention due to its damage to the cardiovascular system. Vascular endothelial dysfunction (VED) is recognized as an i...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1559-8
更新日期：2019-08-01 00:00:00
abstract：:Both selenium and green tea have been reported to exhibit antigenotoxic and cancer chemopreventive properties. We compared the antimutagenic activities of regular green tea and selenium-enriched green tea obtained from Hubei Province, China, toward the heterocyclic amine, 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) i...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:86:2:177
更新日期：2002-05-01 00:00:00
abstract：:Chronic alcoholics frequently show associated malnutrition. Both ethanol and malnutrition exert profound changes on zinc and copper metabolism. In this study, we found higher hair zinc and copper values in 43 male alcoholics than in 39 controls. Hair copper was significantly related to the amount of ethanol consumed, ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/bter:85:3:269
更新日期：2002-03-01 00:00:00
abstract：:We explored the synergistic effect of serine combined with several selenocompounds or used alone on the expression of selenoprotein P (SelP) and glutathione peroxidase (GPx) in this study. We first compared the SelP and GPx expression difference between HepG2 and Hela cells treated with serine and finally chose HepG2 ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0665-8
更新日期：2016-10-01 00:00:00
abstract：:Arsenic (As) is a widespread environmental contaminant present around the world in both organic and inorganic forms. Oxidative stress is postulated as the main mechanism for As-induced toxicity. This study was planned to examine the protective effect of acetyl-L-carnitine (ALC) on As-induced oxidative damage in male r...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0436-y
更新日期：2016-05-01 00:00:00
abstract：:Microcalorimetry was employed to investigate the action of Li(I) to aquatic ecosystem from the point view of bioenergetics. Tetrahymena thermophila BF5 was chosen as the model organism. The power-time curves of T. thermophila BF5 growth metabolism in the absence and presence of Li(I) were obtained. The corresponding t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-0040-x
更新日期：2007-10-01 00:00:00
abstract：:Selenium (Se) mainly performs its function through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, plays important roles in the normal function of the heart. To investigate the possible relationship between Se and SelW for the regulation of oxidative damage in chicken embryo myo...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0529-7
更新日期：2016-06-01 00:00:00
abstract：:Mitochondria from Trigonella foenum-graecum seedlings grown independently in the presence of either selenium (0.75 ppm) or mimosine (0.1 mM) exhibited respiration-stimulated energy-dependent uptake of Ca2+. Uptake studies were carried out independently at a series of Ca2+ concentrations at two different levels: (1) 1-...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:82:1-3:217
更新日期：2001-07-01 00:00:00
abstract：:Concentrations of toxic elements (lead, cadmium, mercury, and arsenic) were measured in water, sediment, and four commercial fish species (Cyprinus carpio, Hypophthalmichthys molitrix, Silurus glanis, and Esox lucius) and their tissues (muscle, liver, and kidney) from Saničani Lake, Bosnia and Herzegovina. The concent...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01982-2
更新日期：2020-09-01 00:00:00
abstract：:CuO nanoparticles (CuO-NPs) serve several important functions in human life, particularly in the fields of medicine, engineering, and technology. These nanoparticles have been utilized as catalysts, semiconductors, sensors, gaseous and solid ceramic pigments, and magnet rotatable devices. Further use for CuO-NPs has b...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1170-4
更新日期：2018-08-01 00:00:00
abstract：:After considering the need for quality control in NAA, the concept of quality in NAA procedures themselves is discussed, and some important factors identified. Two approaches to improve quality are then described in more detail. The first concerns the unique ability of NAA using different isotopic reactions and differ...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/BF02917356
更新日期：1994-10-01 00:00:00
abstract：:The primary objective of the present study is analysis of hair trace elements content in children with communication disorder (CD) and autism spectrum disorder (ASD). A total of 99 children from control, CD, and ASD groups (n = 33) were examined. All children were additionally divided into two subgroups according to a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0878-x
更新日期：2017-06-01 00:00:00
abstract：:Hexavalent chromium, a well-known environmental toxicant, adversely affects female reproduction and results in abnormal implantation, fetal resorption, and reduction in litter size. Uterine myogenic activity is under control of number of receptors and ion channels, and it regulates fetal-implantation and feto-maternal...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02041-x
更新日期：2020-11-01 00:00:00
abstract：:Bulk fabrication of ordered hollow structural particles (HSPs) with large surface area and high biocompatibility simultaneously is critical for the practical application of HSPs in biosensing and drug delivery. In this article, we describe a smart approach for batch synthesis of calcium carbonate nanotubes (CCNTs) bas...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9325-9
更新日期：2012-06-01 00:00:00
abstract：:The present study aimed to evaluate the effect of fluoride (F) on spermatogenesis in male rats. F- at 50 and 100 mg/L was administered for 70 days, after which the testicular and epididymis tissues were collected to observe the histopathological structure under a light microscope. The ultrastructure of the testis and ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1338-6
更新日期：2018-12-01 00:00:00
abstract：:Assessing the ability of a selenium (Se) sample to induce cellular glutathione peroxidase (GPx) activity in Se-deficient animals is the most commonly used method to determine Se bioavailability. Our goal is to establish a Se-deficient cell culture model with differential incorporation of Se chemical forms into GPx, wh...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8097-8
更新日期：2008-07-01 00:00:00
abstract：:This paper aims to compare the Cd, Cu, and Pb concentration in the bone, gills, and muscle of the seven fish species sampled during normal and dry seasons. Cadmium, Cu, and Pb concentrations varied significantly depending on the type of the tissue and season. Bone samples of the Osteochilus hasseltii showed the highes...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8596-2
更新日期：2010-12-01 00:00:00
abstract：:Divalent metal ions (Fe2+, Cu2+, Zn2+, Ni2+, and Mn2+) induced lipid oxidation in cooked, but not in raw fish. The extent of lipid oxidation, measured by the production of thiobarbituric acid reactive substances (TBRS), was increased with higher concentrations of iron, zinc, and nickel, but was decreased with increasi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783896
更新日期：1992-07-01 00:00:00
abstract：:Metallic tin powder injected into Lewis rats caused marked enlargement of draining lymph nodes with prominent hyperplasia of plasma cells. A low level of dietary protein (8%) or deficiency of choline interfered with the cellular proliferation and reduced the size of the nodes by nearly one-third compared to a normal p...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:85:1:71
更新日期：2002-01-01 00:00:00
abstract：:The relaxation rates (1/T(1) and 1/T(2)) in cysts have already been analyzed in terms of materials such as albumin, cholesterol, manganese, iron, and copper. However, the relaxivities of these materials have not been determined yet. In this work, five sets containing the ions, albumin, and cholesterol were prepared by...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8170-3
更新日期：2008-12-01 00:00:00
abstract：:Measurement and monitoring of magnesium (Mg) are important to prevent the development of serious and potentially fatal complications in critically ill patients. Although ion-selective electrodes are available and earlier reports suggest that free ionized magnesium (iMg2+) is the most useful test to estimate Mg status,...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:115:1:13
更新日期：2007-01-01 00:00:00
abstract：:The aim of this study was to establish the possible effects of the sampling protocol (between-breast, within-feed, and diurnal differences) and the mother's personal factors (age, parity, iron supplementation, smoking habits, and lactation period) on the copper, iron, and zinc contents in human milk. One hundred thirt...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1385/BTER:76:3:217
更新日期：2000-09-01 00:00:00
abstract：:Injectable trace minerals (ITMs) could provide a potential alternative way of trace mineral delivery for sick animals. Therefore, evaluation of ameliorative potentials of ITMs (copper, manganese, selenium, and zinc) on the circulating Th1/Th2 cytokine misbalance in Theileria annulata-infected calves was aimed. Forty-t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02263-z
更新日期：2020-06-22 00:00:00
abstract：:Diabetic osteoporosis (DOP) is a complication of diabetes, with the characteristics of bone mineral density (BMD) reduction and bone structure destruction. Zinc was reported has a benefit effect on postmenopausal osteoporosise, it was also has hypoglycemic effect, whether zinc was beneficial on diabetes-induced osteop...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01810-7
更新日期：2020-04-01 00:00:00
