Abstract:
:Six important metal contents (i.e., zinc, barium, magnesium, calcium, copper, and selenium) in blood samples coupled with an ensemble classification algorithm have been used for the classification of normal people and cancer patients. A dataset containing 42 healthy samples and 32 cancer samples was used for experiment. The prediction results from this method outperformed those from the newly developed support vector machine, i.e., a sensitivity of 100%, a specificity of 95.2%, and an overall accuracy of 98.6%. It seems that ELDA coupled with blood element analysis can serve as a valuable tool for diagnosing cancer in clinical practice.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Chen H,Tan C,Wu Tdoi
10.1007/s12011-010-8864-1subject
Has Abstractpub_date
2011-10-01 00:00:00pages
143-52issue
1eissn
0163-4984issn
1559-0720journal_volume
143pub_type
杂志文章abstract::It has been defined that deficiency of trace elements plays an important role in the progression of asthma. However, the relationship between blood zinc (Zn), selenium (Se), and magnesium (Mg) and pulmonary functions in children remains to be clarified. A cross-sectional study was conducted in Wuxi, China, and a total...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-02019-4
更新日期:2020-10-01 00:00:00
abstract::Selenium deficiency is the major cause of exudative diathesis in chicks. Subcutaneous hemorrhage is one of the typical symptoms of the disease. However, the reason for the occurrence of blood exudation remains unknown. In the present study, the vascular smooth muscle cells (VSMCs) were isolated from 17-day-old broiler...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0823-z
更新日期:2017-04-01 00:00:00
abstract::Copper oxide nanoparticles (CuONPs) are widely used in several products and their release into the environment can cause toxicity to major food crops. In this study, toxic responses as a result of CuONPs exposure were studied in soybean (Glycine max L.) seedlings. The plants were grown in 1/2 strength Murashige and Sk...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0106-5
更新日期:2014-12-01 00:00:00
abstract::The movement of copper and zinc from the fertilized egg into the developing embryo and the subsequent association of the two metals with metallothionein-like proteins (MT) of chick liver was investigated. Hepatic levels of MT in 1-d-old chicks, estimated from specifically bound(115m)Cd, were increased eightfold over e...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02988942
更新日期:1983-12-01 00:00:00
abstract::Over the last decade, there has been an increased concern about the health risks from exposure to arsenic at low doses, because of their neurotoxic effects on the developing brain. The exact mechanism underlying arsenic-induced neurotoxicity during sensitive periods of brain development remains unclear, although enhan...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1286-1
更新日期:2018-11-01 00:00:00
abstract::To elucidate age-related changes of mineral contents in human veins, the relative contents (RCs) of elements in the human internal jugular veins, superior and inferior venae cavae, and femoral veins from 27 subjects ranging from 40 to 98 yr old were analyzed by inductively coupled plasma atomic emission spectrometry. ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02820017
更新日期:1998-04-01 00:00:00
abstract::The effectiveness and success of antituberculosis therapy is mainly measured by its ability to identify the organism in the sputum. In certain cases, available tuberculosis tests are not satisfactory and do not provide enough information on the effectiveness of antituberculosis therapy. Copper (Cu), zinc (Zn), and sel...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/BTER:95:1:65
更新日期:2003-10-01 00:00:00
abstract::This study assessed the effect of dietary selenium (Se) deficiency on male reproductive function in chicken. A total of 180 Hy-line laying cocks (1 day old; Weiwei) were randomly divided into 2 groups (n = 90) of Se-deficient chickens and control chickens. The control group was fed a basic diet (containing 0.15 mg of ...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-015-0534-x
更新日期:2016-06-01 00:00:00
abstract::Auxiliary enzymes participate in β-oxidation of unsaturated fatty acids. The objective of the study was to investigate the impact of a moderate zinc deficiency and a high intake of polyunsaturated fat on Δ(3)Δ(2)-enoyl-CoA isomerase (ECI) in the liver and other tissues. Five groups of eight weanling rats each were fed...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9940-8
更新日期:2014-06-01 00:00:00
abstract::The aim of the current study was to assess relationships between multiple metals burden in human seminal plasma and semen quality parameters. Levels of five metals (lead, manganese, copper, arsenic, and selenium) in human seminal plasma were determined by inductively coupled plasma mass spectrometry (ICP-MS), and the ...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-012-9335-7
更新日期:2012-07-01 00:00:00
abstract::Calsyntenin-2 (Clstn2) and calsyntenin-3 (Clstn3) are the members of the cadherin superfamily and function to regulate the postsynaptic activity. Both proteins are known to play an important role in memory and learning. This study was designed to test the hypothesis that exposure of mothers to Pb in drinking water may...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02241-5
更新日期:2020-06-16 00:00:00
abstract::The relationship between Ni-induced hepatic lipid peroxidation (LPO) and the concentrations of Ni and trace elements was investigated in male ICR mice. The protective effects of antioxidants were also examined. Hepatic LPO and the concentrations of Ni, Fe, Cu, and Zn in the liver were enhanced after an ip injection of...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784030
更新日期:1998-02-01 00:00:00
abstract::This in vitro study was designed to assess the impact of divalent (Fe(2+)) or trivalent (Fe(3+)) iron on the activity and oxidative balance of bovine spermatozoa at specific time intervals (0, 2, 8, 16, and 24 h) during an in vitro culture. Forty-five semen samples were collected from adult breeding bulls and diluted ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0288-5
更新日期:2015-09-01 00:00:00
abstract::Selenium is known to be a neuroprotective agent in respect to a number of neuronal diseases and pain. The aim of this study was to evaluate the neuroprotective effect of the oral administration of selenium nanoparticles in rats with spinal cord injury (SCI). Forty adult female rats were randomly assigned to two equal ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1371-5
更新日期:2019-01-01 00:00:00
abstract::The study was undertaken to investigate the influence of alpha-tocopherol on zinc, copper, iron, calcium, magnesium, and potassium concentrations in serum of rats with bleomycin-induced pulmonary fibrosis. Fourteen Wistar albino rats were randomly divided into two groups of seven animals each. The first group was trea...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:114:1:175
更新日期:2006-01-01 00:00:00
abstract::The causes of night blindness in children are multifactorial, and particular consideration has been given to childhood nutritional deficiency, which is the most common problem found in underdeveloped countries. Such deficiency can result in physiological and pathological processes that in turn influence hair compositi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8789-8
更新日期:2011-09-01 00:00:00
abstract::Garlic (Allium sativum) is known to reduce lead toxicity in some species of animals. The objective of this study was to evaluate the efficacy of allicin, one of the most active components of garlic, in the treatment of subacute lead intoxication in sheep. Nine female sheep weighing 25-29 kg orally received a daily dos...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8185-9
更新日期:2008-01-01 00:00:00
abstract::Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy, and particularly seen in China. A deficiency of selenium and iodine is implicated as the main etiological factor for KBD. This meta-analysis aimed to evaluate the differences in the selenium and iodine levels between patients with KBD and healthy ...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析
doi:10.1007/s12011-015-0463-8
更新日期:2016-03-01 00:00:00
abstract::Extracellular Ca2+-influx induced by trivalent metal ions (Fe3+, Al3+, Cr3+, In3+, Ga3+, and La3+) in Ehrlich carcinoma cells is enhanced by ATP. This action seems to be related to the high coordination capacity of the ATP ligand that inhibits the polymerization of the solvated cations taking place at physiological pH...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02820027
更新日期:1998-04-01 00:00:00
abstract::Calcium, magnesium, and zinc balances were determined in eleven young adult college females (mean age, 24.9±2.35) during a 39-d metabolic study when the subjects were fed an adequate calorie and protein diet based on habitually consumed foods. Analysis showed that the dietary contribution of calcium, magnesium, and zi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917454
更新日期:1985-11-01 00:00:00
abstract::The aim of this study was to investigate the protective effect of luteolin on liver Ca, Mg, Zn, Cu, Fe, and Mn content in mice with carbon tetrachloride (CCl4)-induced hepatotoxicity. Additionally, liver metallothionein (MT) expression was studied. Luteolin was administered intraperitoneally (i.p.) as a single 5- or 5...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8181-0
更新日期:2008-01-01 00:00:00
abstract::The primary objective of the present study is analysis of hair trace elements content in children with communication disorder (CD) and autism spectrum disorder (ASD). A total of 99 children from control, CD, and ASD groups (n = 33) were examined. All children were additionally divided into two subgroups according to a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0878-x
更新日期:2017-06-01 00:00:00
abstract::The present study was undertaken to evaluate methylmercury-induced alterations in hepatic enzymes and oxidative stress markers in liver tissue of rainbow trout (Oncorhynchus mykiss) by using a perfusion method, and to explore possible protective effect of vitamin C against these alterations. Forty-eight fish were divi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0241-7
更新日期:2015-05-01 00:00:00
abstract::Selenium is a trace element that, although toxic in higher concentrations, is essential for human and animal health. In this study, we looked at microarray-based gene expression patterns from liver and gastrocnemius tissues in mice fed either a selenium-deficient diet or diets containing sodium selenite, selenomethion...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8894-8
更新日期:2011-11-01 00:00:00
abstract::Conflicting results exist between selenium concentration and preeclampsia. The role of selenium in the development of preeclampsia is unclear. We conducted a meta-analysis to compare the blood selenium level in patients with preeclampsia and healthy pregnant women, and to determine the effectiveness of selenium supple...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s12011-015-0545-7
更新日期:2016-06-01 00:00:00
abstract::The objective of this study was to examine relations between basal metabolic rate (BMR) and cadmium (Cd) accumulation in the liver, kidneys, and duodenum in mice. The 5-month-old mice selected for high (H) and low (L) BMR were exposed for 8 weeks to 0, 10, and 100 μg Cd/mL of drinking water. The H-BMR mice showed sign...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9061-6
更新日期:2011-12-01 00:00:00
abstract::Preeclampsia is a syndrome of unknown etiopathogenesis. Recent studies carried out on preeclampsia have focused on the increase in free radicals in the feto-placental unit with poor perfusion. It is believed that the renin-angiotensin system (RAS) has a role in the poor perfusion of the placenta. It is uncertain wheth...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:113:1:1
更新日期:2006-10-01 00:00:00
abstract::To better understand the relationship between prenatal exposure to heavy metals and trace elements and the risk of adverse pregnancy outcomes, we investigated the status of heavy metals and trace elements level in a Chinese population by collecting umbilical cord blood. Umbilical cord blood heavy metals and trace elem...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0057-x
更新日期:2014-09-01 00:00:00
abstract::The present study was undertaken to investigate the utility of cystatin C (CysC) as an early biomarker of cadmium (Cd)-induced renal injury. The study was carried out on 50 adult male individuals divided into five groups of 10 individuals as follows: control, welders, smoker welders, diabetic welders, and smoker diabe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9939-1
更新日期:2014-06-01 00:00:00
abstract::Three-month studies were performed on 18 adult rabbits of New Zealand breed divided into three groups, with six animals in each: a control group on standard diet, a cholesterol group receiving 500 mg of cholesterol/100 g of feed per rabbit per 24 h (CH group), and a cholesterol + fluorine group (CH + F group) receivin...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8129-4
更新日期:2008-08-01 00:00:00