Abstract:
:The effectiveness and success of antituberculosis therapy is mainly measured by its ability to identify the organism in the sputum. In certain cases, available tuberculosis tests are not satisfactory and do not provide enough information on the effectiveness of antituberculosis therapy. Copper (Cu), zinc (Zn), and selenium (Se) are the essential elements that play a crucial role in the immune system. The serum levels of these elements vary in many diseases including tuberculosis. In this study, we investigate whether the serum levels of Cu, Zn, and Se change during antituberculosis therapy. We have included 22 pulmonary tuberculosis cases that were newly diagnosed with positive sputum and 18 healthy subjects. At the beginning and 2 mo after therapy, serum levels of Cu, Zn, and Se were measured by atomic absorption spectrometry. Despite Se and Cu levels not being affected during the treatment, we found that there was a significant increase in the levels of Zn and a decrease in the Cu/Zn ratio. Serum Zn levels and the Cu/Zn ratio could be used as a valuable laboratory tool for the clinicians to assess response to therapy or effectiveness of the ongoing antituberculosis therapy.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Ciftci TU,Ciftci B,Yis O,Guney Y,Bilgihan A,Ogretensoy Mdoi
10.1385/BTER:95:1:65subject
Has Abstractpub_date
2003-10-01 00:00:00pages
65-71issue
1eissn
0163-4984issn
1559-0720pii
BTER-95-1-65journal_volume
95pub_type
临床试验,杂志文章abstract::The present study was undertaken to evaluate the in vitro availability of chemically varying forms of selenium (Se), supplemented in cow's milk. Two inorganic (selenite and selenate) and two organic (seleno-methionine [Se-Met] and seleno-cystine [Se-Cys]) Se sources were evaluated. The in vitro availability was estima...
journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
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journal_title:Biological trace element research
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journal_title:Biological trace element research
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
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journal_title:Biological trace element research
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journal_title:Biological trace element research
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journal_title:Biological trace element research
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更新日期:2004-09-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
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pub_type: 杂志文章
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