Interaction of Lead with Calcium, Iron, and Zinc in the Biological Samples of Malnourished Children.

Abstract:

:Interaction between toxic and essential elements is of particular interest, because the deficiency of essential element can dramatically increase the absorption rate of toxic metals inside the body. This study was conducted to evaluate the possible correlation of lead (Pb) with calcium (Ca), iron (Fe), and zinc (Zn) in biological samples (whole blood and scalp hair) of malnourished children (MNC). For comparative purposes, age-matched, well-nourished children (WNC) were selected. The concentrations of understudy elements were analyzed by atomic absorption spectrophotometry after microwave acid digestion. The accuracy of the methodology, as well as its its validity and efficiency, was checked through certified reference material of whole blood and scalp hair. The result indicates that the MNC have a twofold higher level of Pb, while the levels of essential elements (Ca, Fe, and Zn) were onefold to twofold lower as compared to the WNC (p < 0.05). Significant negative correlations of Pb with Ca, Fe, and Zn were found in the studied malnourished population at p < 0.05. Further research studies are required to elucidate the role of these metals and the mechanism of interaction inside the body.

journal_name

Biol Trace Elem Res

authors

Talpur S,Afridi HI,Kazi TG,Talpur FN

doi

10.1007/s12011-017-1141-9

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

209-217

issue

2

eissn

0163-4984

issn

1559-0720

pii

10.1007/s12011-017-1141-9

journal_volume

183

pub_type

杂志文章
  • Trace elements in different brands of yerba mate tea.

    abstract::Yerba mate (Ilex paraguariensis), a widely consumed beverage in South America, contains various biochemically active substances, among them are several minerals. This paper reports on the results of a survey of trace elements in the yerba mate infusions. Three different commercially available trademarks of I. paraguar...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9056-3

    authors: Bragança VL,Melnikov P,Zanoni LZ

    更新日期:2011-12-01 00:00:00

  • Preliminary study on the relationship between osteoporosis and trace elements with rat models.

    abstract::Thirty rats were divided randomly into five groups and fed with different feeds. They were killed after 2 mo. Right thighs of these rats were taken as samples. Bone mineral densities of these samples were measured by the double-energy x-ray bone mineral densitometer, and trace elements contents of the samples were ana...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02784252

    authors: Nie H,Qin L,Tian W,Ni B,Bao A,Wang P

    更新日期:1999-01-01 00:00:00

  • Seasonal and locational effects on serum, milk, liver and kidney chromium, manganese, copper, zinc, and iron concentrations of dairy cows.

    abstract::Chromium (Cr), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe) concentrations were quantified in serum (n = 112), milk (n = 112), liver (n = 70), and kidney samples (n = 67) of dairy cows from an iron-steel processing region (Payas-Iskenderun) and from an area free of industrial pollution (Antakya) in Hatay, loc...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:98:1:51

    authors: Erdogan S,Celik S,Erdogan Z

    更新日期:2004-04-01 00:00:00

  • Transformation of tributyltin in zebrafish eleutheroembryos (Danio rerio).

    abstract::Organotin compounds are highly versatile group of organometallic chemicals used in industrial and agricultural applications. Their endocrine-disrupting effects are well known and their extensive uses as biocide materials, e.g., in antifouling paints, for many years have led to serious environmental problems. So far, a...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0144-z

    authors: Borges AR,López-Serrano Oliver A,Gallego-Gallegos M,Muñoz-Olivas R,Rodrigues Vale MG,Cámara C

    更新日期:2014-12-01 00:00:00

  • Analysis of Relations Between the Level of Mg, Zn, Ca, Cu, and Fe and Depressiveness in Postmenopausal Women.

    abstract::Numerous observations suggest a possible connection between the levels of Mg, Zn, Fe, and Zn and the incidence of depressive symptoms. Depression is two to three times more common in women than in men. The menopausal period is extremely conducive to depressive disorders. The aim of this study was to assess the severit...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0798-9

    authors: Szkup M,Jurczak A,Brodowska A,Brodowska A,Noceń I,Chlubek D,Laszczyńska M,Karakiewicz B,Grochans E

    更新日期:2017-03-01 00:00:00

  • Induction of rat liver glutathione transferase isoenzyme 7-7 by lead nitrate.

    abstract::The glutathione transferase (GST) activity of rat liver cytosolic preparations with ethacrynic acid (EA) and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydro-benzo(a)pyrene (BPDE) as substrates, increased by 125 and 350%, respectively, in animals that had been treated with a single intraveno...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917265

    authors: Dock L

    更新日期:1989-07-01 00:00:00

  • Seasonal variation of cadmium, copper, and lead concentrations in fish from a freshwater lake.

    abstract::This paper aims to compare the Cd, Cu, and Pb concentration in the bone, gills, and muscle of the seven fish species sampled during normal and dry seasons. Cadmium, Cu, and Pb concentrations varied significantly depending on the type of the tissue and season. Bone samples of the Osteochilus hasseltii showed the highes...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-009-8596-2

    authors: Ebrahimpour M,Mushrifah I

    更新日期:2010-12-01 00:00:00

  • Correlation between maternal plasma homocysteine and zinc levels in preeclamptic women.

    abstract::Women with preeclampsia have been shown to have elevated blood levels of the metabolite homocysteine, and alterations in blood levels of zinc and copper have also been reported. This study measured plasma levels of zinc, copper, and homocysteine in women with preeclampsia and in women with healthy, normotensive pregna...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:104:2:097

    authors: Harma M,Harma M,Kocyigit A

    更新日期:2005-05-01 00:00:00

  • Evaluation of toxic risk assessment of arsenic in male subjects through drinking water in southern Sindh Pakistan.

    abstract::The arsenic (As) hazardous quotient was estimated based on concentration of As in drinking water and scalp hair of male subjects of two age groups (n=360) consuming As contaminated water at different levels and non-contaminated drinking water. The total As concentrations in drinking water of less-exposed (LE) and high...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8933-5

    authors: Baig JA,Kazi TG,Shah AQ,Afridi HI,Khan S,Kolachi NF,Kandhro GA,Wadhwa SK,Shah F

    更新日期:2011-11-01 00:00:00

  • Tissue cadmium accumulation is associated with basal metabolic rate in mice.

    abstract::The objective of this study was to examine relations between basal metabolic rate (BMR) and cadmium (Cd) accumulation in the liver, kidneys, and duodenum in mice. The 5-month-old mice selected for high (H) and low (L) BMR were exposed for 8 weeks to 0, 10, and 100 μg Cd/mL of drinking water. The H-BMR mice showed sign...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9061-6

    authors: Maciak S,Włostowski T,Salińska A,Bonda-Ostaszewska E

    更新日期:2011-12-01 00:00:00

  • Oral treatment of pressure ulcers with polaprezinc (zinc L-carnosine complex): 8-week open-label trial.

    abstract::Polaprezinc (zinc L-carnosine complex) is a tablet commonly prescribed for gastric ulcers in Japan. Recently, we reported the effects of polaprezinc on pressure ulcer healing at 4-week follow-up. We aimed to further evaluate the efficacy and safety of polaprezinc in 8-week treatment for chronic pressure ulcers. Patien...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12011-014-9943-5

    authors: Sakae K,Yanagisawa H

    更新日期:2014-06-01 00:00:00

  • Detection and determination of selenoproteins by nuclear techniques.

    abstract::Microbeam X-ray spectrometry, energy-dispersive X-ray fluorescence analysis, and neutron activation analysis were evaluated for the detection of selenium contained in the selenoprotein glutathione peroxidase. The glutathione peroxidase had been previously separated using polyacrylamide gel electrophoresis. The use of ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917328

    authors: Stone SF,Bernasconi G,Haselberger N,Makarewicz M,Ogris R,Wobrauschek P,Zeisler R

    更新日期:1994-10-01 00:00:00

  • Enhanced sensitivity for the determination of selenium by INAA.

    abstract::A working analytical procedure for selenium determinations by INAA, using gamma spectrometry with a germanium well-type detector, is presented. The spectral line at 400.7 keV is employed, enhanced with the effect of energy summing in true coincidence of cascade photons. The main advantage of the method is high efficie...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917304

    authors: Makarewicz M,Zeisler R

    更新日期:1994-10-01 00:00:00

  • Iron: a Strong Element in the Pathogenesis of Chronic Hyperglycaemia After Acute Pancreatitis.

    abstract::Evidence shows an association between markers of iron metabolism and glucose metabolism in type 2 diabetes mellitus. Acute pancreatitis is the largest contributor to diabetes of the exocrine pancreas. However, the pathogenesis of new-onset pre-diabetes or diabetes after pancreatitis remains unclear. This study aimed t...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12011-017-1131-y

    authors: Chand SK,Singh RG,Pendharkar SA,Petrov MS

    更新日期:2018-05-01 00:00:00

  • Effects of selenium-enriched Agaricus blazei Murill on liver metabolic dysfunction in mice, a comparison with selenium-deficient Agaricus blazei Murill and sodium selenite.

    abstract::In the present study, we investigated the effects of Se-enriched Agaricus blazei Murill (Se-AbM) on liver injury in mice induced by acute alcohol administration. Mice received ethanol (5 g/kg body weight (BW)) by gavage every 12 h for a total of 3 doses. Se-AbM was administrated before ethanol administration. Subseque...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0022-8

    authors: Yu L,Yang S,Sun L,Jiang YF,Zhu LY

    更新日期:2014-07-01 00:00:00

  • Dephytinization of a rat diet. Consequences for mineral and trace element absorption.

    abstract::Soaking of a rat diet, high in both plant phytate and phytase, progressively degraded the phytate content with time of soaking. This dephytinization in turn enhanced the digestion of feed organic matter in the animals, and it significantly improved the absorption and retention of minerals and trace elements as observe...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783810

    authors: Larsen T

    更新日期:1993-10-01 00:00:00

  • Use of 2-Hydrazinobenzothiazole-Modified Copolymer(s) as Potential Chelating Agent for Sensitive and Selective Determination of Low Levels of Mercury in Seafood by Ultrasound-Assisted Cloud-Point Extraction Combined with Spectrophotometry.

    abstract::In this study, a new method was developed for the pre-concentration of trace mercury from seafood samples prior to analysis by spectrophotometry. The method is based on the complexation between 2-hydrazinobenzothiazole (2-HBT)-modified copolymer(s) and Hg(II) in the presence of an ionic surfactant, cetyltrimethylammon...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1614-5

    authors: Zengin HB,Gürkan R

    更新日期:2019-09-01 00:00:00

  • Mechanism of chromium(VI) carcinogenesis. Reactive intermediates and effect on gene expression.

    abstract::Since chromium(VI) is unreactive toward DNA under physiological conditions in vitro, the ability of carcinogenic chromium(VI) compounds to damage DNA depends on the presence of cellular redox components that reduce chromium(VI) to reactive species capable of interacting with DNA. We have examined the role of glutathio...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/BF02917282

    authors: Wetterhahn KE,Hamilton JW,Aiyar J,Borges KM,Floyd R

    更新日期:1989-07-01 00:00:00

  • Effects of ionic valency of interacting metal elements in ion uptake by carrot (Daucas carota cv. U.S. harumakigosun).

    abstract::Interaction of elements in the course of element uptake by carrot (Daucas carota cv. U.S. harumakigosun) exerted by the addition of elements, such as Rb, Zn, and Al, was investigated. For the purpose of precise evaluation of uptake behavior, the simultaneous determination of absorption of Na, Be, Sr, Mn, Co, Zn, Ce, P...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/bter:84:1-3:197

    authors: Ozaki T,Ambe S,Minai Y,Enomoto S,Yatagai F,Abe T,Yoshida S,Makide Y

    更新日期:2001-01-01 00:00:00

  • Stimulation of urinary copper excretion by trientine((R)) in nickel-sensitive patients.

    abstract::Trientine((R)) is not an effective drug for the treatment of intractable hand dermatitis in nickel-sensitive patients. In a controlled, double-blind study this chelator, on oral administration, failed to stimulate nickel excretion. Early morning urine samples from two groups of nine patients were analyzed by atomic ab...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02795597

    authors: McMaster D,Burrows D,Eedy DJ,Love AH

    更新日期:1987-10-01 00:00:00

  • Serum Copper Homeostasis in Hypertensive Intracerebral Hemorrhage and its Clinical Significance.

    abstract::This study was to investigate the alterations of serum copper homeostasis after hypertensive intracerebral hemorrhage (ICH), which is not yet clear. We recruited 85 hypertensive ICH patients and determined their serum levels of total copper (TCu), small molecule copper (SMC), and ceruloplasmin (Cp). Sera from 32 healt...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-017-1227-4

    authors: Han M,Ding S,Zhang Y,Lin Z,Li K

    更新日期:2018-09-01 00:00:00

  • Copper Induces Apoptosis Through Endoplasmic Reticulum Stress in Skeletal Muscle of Broilers.

    abstract::The purpose of this research was to investigate whether copper (Cu) exposure could induce apoptosis via endoplasmic reticulum stress (ERS) in skeletal muscle of broilers. A total of 240 one-day-old chickens were randomly divided into four groups by free access; the diets are as follows: control diet (Cu 11 mg/kg, cont...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02076-0

    authors: Guo J,Bai Y,Liao J,Wang S,Han Q,Tang Z

    更新日期:2020-12-01 00:00:00

  • The Concentration and Probabilistic Health Risk of Potentially Toxic Elements (PTEs) in Edible Mushrooms (Wild and Cultivated) Samples Collected from Different Cities of Iran.

    abstract::The present study was devoted to investigate the PTE concentrations including cadmium (Cd), chromium (Cr), copper(Cu), iron (Fe), mercury (Hg), manganese (Mn), nickel (Ni), lead (Pb), arsenic(As), and zinc (Zn) among six types of edible wild, 23 cultivated mushroom samples collected from Iran's market by the aid of an...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02130-x

    authors: Karami H,Shariatifar N,Nazmara S,Moazzen M,Mahmoodi B,Mousavi Khaneghah A

    更新日期:2021-01-01 00:00:00

  • Associations Between Serum Zinc Levels and Alanine Aminotransferase Elevation in Adults.

    abstract::Recent findings showed that zinc might be linked to alanine aminotransferase (ALT) elevation. This analysis aimed to explore the association between serum zinc levels and ALT elevation in adults. Data on serum zinc and ALT levels from adults aged 20 years and older who participated in the 2011-2016 National Health and...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02318-1

    authors: Hu J,Cai X,Li J,Zheng N,Zhang J

    更新日期:2020-07-31 00:00:00

  • Chromium in Postmortem Material.

    abstract::Recently, considerable attention has been paid to the negative effects caused by the presence and constant increase in concentration of heavy metals in the environment, as well as to the determination of their content in human biological samples. In this paper, the concentration of chromium in samples of blood and int...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1328-8

    authors: Dudek-Adamska D,Lech T,Konopka T,Kościelniak P

    更新日期:2018-12-01 00:00:00

  • Effects of dietary combination of chromium and biotin on egg production, serum metabolites, and egg yolk mineral and cholesterol concentrations in heat-distressed laying quails.

    abstract::Chromium picolinate is used in the poultry diet because of its antistress effects in addition to the fact that the requirement for it is increased during stress. This study was conducted to determine if the negative effects of high ambient temperature (34 degrees C) on egg production, egg quality, antioxidant status, ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:101:2:181

    authors: Sahin K,Onderci M,Sahin N,Gursu MF,Vijaya J,Kucuk O

    更新日期:2004-11-01 00:00:00

  • Uptake of 45Ca by mitochondria of Trigonella foenum-graecum as influenced by selenium and mimosine--detailed kinetic analyses.

    abstract::Mitochondria from Trigonella foenum-graecum seedlings grown independently in the presence of either selenium (0.75 ppm) or mimosine (0.1 mM) exhibited respiration-stimulated energy-dependent uptake of Ca2+. Uptake studies were carried out independently at a series of Ca2+ concentrations at two different levels: (1) 1-...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:82:1-3:217

    authors: Sreekala M,Lalitha K

    更新日期:2001-07-01 00:00:00

  • Zinc and propolis reduces cytotoxicity and proliferation in skin fibroblast cell culture: total polyphenol content and antioxidant capacity of propolis.

    abstract::It has been demonstrated that zinc exerts its beneficial influence on skin fibroblasts. Propolis, a complex mixture of plant-derived and bees' products, was reported to stimulate cicatrization processes in skin and prevent infections. The aim of this study was to find out how zinc and propolis influence human skin fib...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0019-3

    authors: Tyszka-Czochara M,Paśko P,Reczyński W,Szlósarczyk M,Bystrowska B,Opoka W

    更新日期:2014-07-01 00:00:00

  • Possible correlation between selenoprotein W and myogenic regulatory factors in chicken embryonic myoblasts.

    abstract::The biological function of selenium (Se) is mainly elicited through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, is essential for the normal function of the skeletal muscle system. To investigate the possible relationship of Se in the process of differentiation in chicken myo...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9520-8

    authors: Wu Q,Yao HD,Zhang ZW,Zhang B,Meng FY,Xu SW,Wang XL

    更新日期:2012-12-01 00:00:00

  • Correlation between serum electrolytes and fasting glucose and Hb1Ac in Saudi diabetic patients.

    abstract::In subjects with impaired insulin action, alterations of the serum sodium and potassium concentrations have been reported. The resulting cationic imbalance, along with the osmotic effect of the elevated sugar levels, could influence the course of diabetes mellitus management. Therefore, this study was conducted to com...

    journal_title:Biological trace element research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s12011-011-9144-4

    authors: Al-Rubeaan K,Siddiqui K,Abu Risheh K,Hamsirani R,Alzekri A,Alaseem A,Saleh SM,Al-Yami Z,Al-Ghamdi A,Alayed K

    更新日期:2011-12-01 00:00:00