Abstract:
:The increase in the prevalence of metabolic disorders globally is becoming a public health concern. Previous studies have reported an association between environmental exposures to hazardous substances, including various heavy metals, and the risk for metabolic syndrome. However, reports on the contributions of cadmium (Cd) to the risk for obesity and diabetes remain inconsistent. This study aims to investigate an association between serum Cd levels (SCL) and diabesity and dyslipidemia risk scores. A total of 140 subjects were identified from a public academic institution in Lebanon. Socio-demographic information, diabesity, and obesity risk scores were determined using an interview-based adapted FINDRISC questionnaire and analysis of an acquired blood sample. SCL was quantified using inductively coupled plasma mass spectrometry (ICP-MS). The statistical analysis relied on a chi-squared test and multivariate logistic regression models, along with checks for confounders and effect modifiers. Our results showed a Cd geometric mean of 4.04 μg/L (± 2.5). High SCL was significantly associated with higher dyslipidemia risk (OR: 3.05 [95% CI: 1.19-7.86], P = 0.02), even after adjusting for confounders. However, SCL did not show a statistically significant association with diabetes and obesity outcomes. Elevated SCL increases the risk of dyslipidemia and alters the blood lipid profile. In addition, our findings do not support a role for Cd in diabesity.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Ayoub N,Mantash H,Dhaini HR,Mourad A,Hneino M,Daher Zdoi
10.1007/s12011-020-02502-3subject
Has Abstractpub_date
2021-01-06 00:00:00eissn
0163-4984issn
1559-0720pii
10.1007/s12011-020-02502-3pub_type
杂志文章abstract::Our previous studies showed that serum calcium level may have influence in the blood pressure to older male subjects, but the relationship between serum calcium level and blood lipids is unclear. The aim of this study was to evaluate the relationship between total serum calcium level and blood lipids. In our study, to...
journal_title:Biological trace element research
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journal_title:Biological trace element research
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:2003-12-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9668-x
更新日期:2013-06-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:102:1-3:209
更新日期:2004-01-01 00:00:00
abstract::The efficacy of selenate and other divalent anions to stimulate the efflux of radiolabeled sulfate from lactating rat mammary tissue slices has been examined. Both selenate and sulfate markedly increased the fractional release of sulfate via a system that is temperature-sensitive and sensitive to the anion-exchange in...
journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:1990-03-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
abstract::Selenium selenate was administered to streptozotocin-induced diabetic rats to assess its effects on the detrusor muscle. Thirty-two rats were divided into four groups of eight subjects each. The study animals were made diabetic by means of a single intravenous injection of streptozotocin (STZ). The responsiveness of t...
journal_title:Biological trace element research
pub_type: 杂志文章
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abstract::Fluoride can induce neurotoxicity, but the mechanism is not clear. In this study, we explored the role of autophagy in F--induced neurotoxicity of Wistar rats. Eighty Wistar rats were randomly divided into four groups: the control group (distilled water containing less than 0.1 mg/L F-) and three NaF-treated groups (F...
journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
abstract::Selenoprotein T (SelT) is associated with the regulation of calcium homeostasis and neuroendocrine secretion. SelT can also change cell adhesion and is involved in redox regulation and cell fixation. However, the structure and function of chicken SelT and its response to selenium (Se) remains unclear. In the present s...
journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
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abstract::Preoperative diagnosis of papillary thyroid carcinoma (PTC) comprises numerous diagnostic procedures which are mostly applicable in tertiary institutions. Normal thyroid function depends on the presence of many trace elements and copper (Cu) and zinc (Zn) are some of those. The study is based on retrospective review o...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章,meta分析
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