Evaluation of status of zinc, copper, and iron levels in biological samples of normal children and children with night blindness with age groups of 3-7 and 8-12 years.

Abstract:

:The causes of night blindness in children are multifactorial, and particular consideration has been given to childhood nutritional deficiency, which is the most common problem found in underdeveloped countries. Such deficiency can result in physiological and pathological processes that in turn influence hair composition. This study was designed to compare the levels of zinc (Zn), copper (Cu), and iron (Fe) in scalp hair, blood, and urine of both genders of children with night blindness with age range of 3-7 and 8-12 years, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure was developed as a sample pretreatment, for the determination of zinc, copper, and iron in biological samples of children with night blindness. The proposed method was validated by using conventional wet digestion and certified reference samples of hair, blood, and urine. The digests of all biological samples were analyzed for Cu, Fe, and Zn by flame atomic absorption spectrometry using an air/acetylene flame. The results indicated significantly lower levels of Fe, Cu, and Zn in the biological samples (blood and scalp hair) of male and female children with night blindness, compared with control subjects of both genders. These data present guidance to clinicians and other professionals investigating the deficiency of essential trace metals in biological samples (scalp hair and blood) of children with night blindness.

journal_name

Biol Trace Elem Res

authors

Afridi HI,Kazi TG,Kazi N,Kandhro GA,Baig JA,Shah AQ,Wadhwa SK,Khan S,Kolachi NF,Shah F,Jamali MK,Arain MB,Sirajuddin

doi

10.1007/s12011-010-8789-8

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

323-34

issue

3

eissn

0163-4984

issn

1559-0720

journal_volume

142

pub_type

杂志文章
  • Oral treatment of pressure ulcers with polaprezinc (zinc L-carnosine complex): 8-week open-label trial.

    abstract::Polaprezinc (zinc L-carnosine complex) is a tablet commonly prescribed for gastric ulcers in Japan. Recently, we reported the effects of polaprezinc on pressure ulcer healing at 4-week follow-up. We aimed to further evaluate the efficacy and safety of polaprezinc in 8-week treatment for chronic pressure ulcers. Patien...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12011-014-9943-5

    authors: Sakae K,Yanagisawa H

    更新日期:2014-06-01 00:00:00

  • Investigation of the effects of phosphate fertilizer application on the heavy metal content in agricultural soils with different cultivation patterns.

    abstract::The use of phosphate fertilizers is essential in agriculture, because they supply farmland with nutrients for growing plants. However, heavy metals might be included as impurities in natural materials and minerals, so heavy metals can also be present in phosphate fertilizers or other chemical fertilizers. The aim of t...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9161-3

    authors: Cheraghi M,Lorestani B,Merrikhpour H

    更新日期:2012-01-01 00:00:00

  • Luteolin reduces zinc-induced tau phosphorylation at Ser262/356 in an ROS-dependent manner in SH-SY5Y cells.

    abstract::In brain, excess zinc alters the metabolism of amyloid precursor protein, leading to β-amyloid protein deposition, one of the hallmarks of Alzheimer's disease (AD) pathology. Recently, it has been reported that zinc accelerates in vitro tau fibrillization, another hallmark of AD. In the current study, we examined the ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9411-z

    authors: Zhou F,Chen S,Xiong J,Li Y,Qu L

    更新日期:2012-11-01 00:00:00

  • Comparison of angiotensin-converting enzyme, malonaldehyde, zinc, and copper levels in preeclampsia.

    abstract::Preeclampsia is a syndrome of unknown etiopathogenesis. Recent studies carried out on preeclampsia have focused on the increase in free radicals in the feto-placental unit with poor perfusion. It is believed that the renin-angiotensin system (RAS) has a role in the poor perfusion of the placenta. It is uncertain wheth...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:113:1:1

    authors: Açikgoz S,Harma M,Harma M,Mungan G,Can M,Demirtas S

    更新日期:2006-10-01 00:00:00

  • Biological Evaluation of Hot-Melt Extruded Nano-selenium and the Role of Selenium on the Expression Profiles of Selenium-Dependent Antioxidant Enzymes in Chickens.

    abstract::A study was conducted to determine the effect of dietary selenium (Se) concentration and source for broiler chickens on performance, nutrient digestibility, plasma Se, glutathione peroxidase (GPx) activity, and thiobarbituric acid reactive substances (TBARS). A total of 700 1-day-old broiler chicks were assigned to 7 ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01801-8

    authors: Lee J,Hosseindoust A,Kim M,Kim K,Choi Y,Lee S,Lee S,Cho H,Kang WS,Chae B

    更新日期:2020-04-01 00:00:00

  • Leptin concentration and the Zn/Cu ratio in plasma in women with thyroid disorder.

    abstract::We investigated the possible correlation between the leptin concentration and the Zn/Cu ratio in the plasma of women with thyroid disorder. Forty women with hypothyroidism (n = 20) or hypothyroidism (n = 20) and 20 euthyroid controls were recruited. The results showed that the women with thyroid disorder (hypothyroidi...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章

    doi:10.1385/BTER:75:1-3:99

    authors: Chen MD,Song YM,Tsou CT,Lin WH,Sheu WH

    更新日期:2000-07-01 00:00:00

  • Use of stringent selection parameters for the identification of possible selenium-responsive marker genes in mouse liver and gastrocnemius.

    abstract::Selenium is a trace element that, although toxic in higher concentrations, is essential for human and animal health. In this study, we looked at microarray-based gene expression patterns from liver and gastrocnemius tissues in mice fed either a selenium-deficient diet or diets containing sodium selenite, selenomethion...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8894-8

    authors: Mallonee DH,Crowdus CA,Barger JL,Dawson KA,Power RF

    更新日期:2011-11-01 00:00:00

  • Synergistic Effects of Genistein and Zinc on Bone Metabolism and the Femoral Metaphyseal Histomorphology in the Ovariectomized Rats.

    abstract::In this study, we evaluated the synergistic effects of genistein and zinc on bone metabolism, bone mineral density, and the femoral metaphyseal histomorphology in the ovariectomized rats. Sixty female Sprague-Dawley rats, aged 13 weeks, were divided into sham-operated group (SHAM), ovariectomized group (OVX), genistei...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-017-1134-8

    authors: Qi S

    更新日期:2018-06-01 00:00:00

  • Glutathione peroxidase (GSHPx) activity in the liver of red deer in relation to hepatic selenium concentrations, sex, body weight and season of the year.

    abstract::The purpose of this study was to determine glutathione peroxidase (GSHPx) activity in the liver of red deer in relation to selenium concentrations in the liver, as well as to evaluate changes in GSHPx activity according to sex, body weight and season of the year. Total selenium concentration in the liver of red deer a...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9022-0

    authors: Pilarczyk B,Drozd R,Pilarczyk R,Tomza-Marciniak A,Jankowiak D,Hendzel D,Kuba J,Kowalska J

    更新日期:2011-12-01 00:00:00

  • Nuclear microscopy in the life sciences at the National University of Singapore. A review.

    abstract::The nuclear microscope is now gaining popularity in the field of life sciences. In particular, the combination of proton-induced X-ray emission to measure the elemental concentrations of inorganic elements, Rutherford backscattering spectrometry to characterize the organic matrix, and scanning transmission ion microsc...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/BF02784192

    authors: Ren MQ,Thong PS,Makjanic J,Ponraj D,Watt F

    更新日期:1999-01-01 00:00:00

  • The susceptibility to stress-induced gastric injury of rats exposed to cadmium.

    abstract::In this experimental study, the effect of cadmium on cold and restraint stress-induced gastric lesions has been studied. Rats received 15 micrograms/mL cadmium-containing water for 30 d, and at the end of this period, they were subjected to cold and restraint stress. Cadmium accumulation in gastric mucosa was associat...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02790120

    authors: Oner G,Izgüt VN,Sentürk UK

    更新日期:1995-01-01 00:00:00

  • Vanadium and tungsten derivatives as antidiabetic agents: a review of their toxic effects.

    abstract::Tungstate is an oxyanion that has biological similarities to vanadate. In recent years, a number of studies have shown the antidiabetic effects of oral tungstate in animal models of diabetes. However, because of the tissue accumulation and potential toxicity derived from chronic administration of vanadium and tungsten...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1385/BTER:88:2:097

    authors: Domingo JL

    更新日期:2002-08-01 00:00:00

  • Effects of statins on oxidative stress.

    abstract::Free oxygen radicals and insufficient antioxidant enzymes have been implicated in the pathogenesis of hypercholesterolemia (HC). Trace elements function as cofactors in antioxidant enzymes. Antioxidant system and trace elements were investigated in many different studies including HC, but these subjects have not been ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:98:2:119

    authors: Yilmaz MI,Baykal Y,Kilic M,Sonmez A,Bulucu F,Aydin A,Sayal A,Kocar IH

    更新日期:2004-05-01 00:00:00

  • Zinc deficiency decreases the activity of calmodulin regulated cyclic nucleotide phosphodiesterases in vivo in selected rat tissues.

    abstract::The effect of zinc deficiency on calmodulin function was investigated by assessing the in vivo activity of two calmodulin regulated enzymes, adenosine 3',5'-monophosphate (c-AMP) and guanosine 3',5'-monophosphate (c-GMP) phosphodiesterase (PDE) in several rat tissues. Enzymatic activities in brain, heart, and testis o...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02797137

    authors: Law JS,McBride SA,Graham S,Nelson NR,Slotnick BM,Henkin RI

    更新日期:1988-08-01 00:00:00

  • Effects of zinc on interleukins and antioxidant enzyme values in psoriasis-induced mice.

    abstract::The effects of zinc chloride (ZnCl2), disodium zinc ethylenediamine tetraacetate (Zn-EDTA), and zinc gluconate (Zn-GLU) on the antioxidant enzyme activities and levels of interleukins (ILs) in psoriasis-induced mice were studied. One hundred twenty female mice were randomly divided into six groups with 20 mice in each...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9799-0

    authors: Yin LL,Zhang Y,Guo DM,An K,Yin MS,Cui X

    更新日期:2013-12-01 00:00:00

  • A new microcomputer-controlled neutron activation and analysis system. Description and applications for the analysis of bioenvironmental specimens.

    abstract::A microcomputer-controlled irradiation and measurement system and a microprocessor-controlled sample changer have been installed at the SLOWPOKE-2 Facility at the Royal Military College of Canada (RMC). These systems can provide the gamut of instrumental neutron activation analysis (INAA) techniques for the analyst. C...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02992658

    authors: Edward JB,Beeley PA,Bennett LG,Poland JS

    更新日期:1990-07-01 00:00:00

  • Effects of taurine on oxidative stress parameters and chromium levels altered by acute hexavalent chromium exposure in mice kidney tissue.

    abstract::The kidney has been regarded as a critical organ of toxicity induced by acute exposure to hexavalent chromium [Cr(VI)] compounds. Reactive intermediates and free radicals generated during reduction process might be responsible for Cr(VI) toxicity. In this study, the effects of pretreatment or posttreatment of taurine ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:102:1-3:209

    authors: Boşgelmez II,Güvendik G

    更新日期:2004-01-01 00:00:00

  • Characterization, Cytotoxicity, and Genotoxicity of TiO2 and Folate-Coupled Chitosan Nanoparticles Loading Polyprenol-Based Nanoemulsion.

    abstract::The structure and bioactivity of Ginkgo biloba leaves polyprenol (GBP) are similar to that of dolichol which widely exists in human and mammalian organs. GBP possesses potential pharmacological activities against cancer. This study involved oil-in-water type nanoemulsion (NE) loading GBP was prepared by dissolving pol...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-017-1184-y

    authors: Tao R,Wang C,Zhang C,Li W,Zhou H,Chen H,Ye J

    更新日期:2018-07-01 00:00:00

  • Magnesium, zinc, and manganese in atherosclerosis of the aorta.

    abstract::Atomic absorption spectrometry was used in a quantitative study of zinc, magnesium, and manganese on 71 postmortal human aortas. Samples were obtained from accident victims 35-65 years of age. Fibrous plaques had higher levels of all three elements when compared to normal aortic tissue. The difference was significant ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02916613

    authors: Mendis S

    更新日期:1989-12-01 00:00:00

  • Investigating the Essentiality and Requirements of Iron from the Ancient to the Present.

    abstract::This review discusses the development of studies that evaluated the essentiality and requirements of iron from the ancient to the present. The therapeutic effects of iron compounds were recognized by the ancient Greeks and Romans. The earliest recognition of the essentiality of iron was stated by Paracelsus, a disting...

    journal_title:Biological trace element research

    pub_type: 历史文章,杂志文章,评审

    doi:10.1007/s12011-018-1584-7

    authors: Yokoi K

    更新日期:2019-03-01 00:00:00

  • Biological monitoring, by in vivo XRF measurements, of occupational exposure to lead, cadmium, and mercury.

    abstract::In vivo X-ray fluorescence (XRF) techniques were used for biological monitoring of lead, cadmium, and mercury. Lead accumulates in bone, the level of which may thus be used for monitoring of exposure. However, there was no close association between lead levels in bone and exposure time, partly because of differences i...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02796636

    authors: Skerfving S,Christoffersson JO,Schütz A,Welinder H,Spång G,Ahlgren L,Mattsson S

    更新日期:1987-08-01 00:00:00

  • Effects of sodium selenite on aflatoxin B1-induced decrease of ileal IgA+ cell numbers and immunoglobulin contents in broilers.

    abstract::This study was aimed to assess the protective effect of sodium selenite on the ileum mucosal immunologic injury induced by AFB1. One hundred eighty-one-day-old healthy male Avian broilers were divided into four groups of three replicates and 15 birds per replicate and fed with basal diet (control group), 0.3 mg/kg AFB...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0035-3

    authors: He Y,Fang J,Peng X,Cui H,Zuo Z,Deng J,Chen Z,Geng Y,Lai W,Shu G,Tang L

    更新日期:2014-07-01 00:00:00

  • Functional Improvement in Rats' Pancreatic Islets Using Magnesium Oxide Nanoparticles Through Antiapoptotic and Antioxidant Pathways.

    abstract::According to undiscovered toxicity and safety of magnesium oxide nanoparticles (MgO NPs) in isolated pancreatic islet cells, this study was designed to examine the effects of its various concentrations on a time-course basis on the oxidative stress, viability, and function of isolated islets of rat's pancreas. Pancrea...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0754-8

    authors: Moeini-Nodeh S,Rahimifard M,Baeeri M,Abdollahi M

    更新日期:2017-01-01 00:00:00

  • Application of electron energy loss spectroscopy and electron spectroscopic imaging to aluminum determination in biological tissue.

    abstract::Electron energy loss spectroscopy (EELS) is a high spatial resolution electron microscopic technique with the potential to quantify elements at the subcellular level. The presence of each element is demonstrated by the electron energy loss edge at the energy characteristic of that element. The area of the edge may ind...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02916819

    authors: Xie X,Yokel RA,Markesbery WR

    更新日期:1994-01-01 00:00:00

  • The acute and chronic effects of monosodium L-glutamate on serum iron and total iron-binding capacity in the jugular artery and vein of pigs.

    abstract::We analyzed the effects of acute and chronic oral administration of monosodium L-glutamate (MSG) on serum iron (Fe) levels and total iron-binding capacity (TIBC) in piglets. In the first experiment, 12 piglets were randomly assigned to two groups: one fed a standard diet (SD) and the other fed an SD containing MSG (10...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9668-x

    authors: Xin W,Xugang S,Xie C,Li J,Hu J,Yin YL,Deng ZY

    更新日期:2013-06-01 00:00:00

  • Metal determination by EDXRF in lichens. A contribution to pollutants monitoring.

    abstract::Samples of Evernia prunastri, collected in a mountainous zone, were exposed in urban and highly industrialized areas in order to monitor the atmospheric pollution. Amounts of Cr, Mn, Fe, Ni, Cu, Zn, and Pb were determined by EDXRF spectrometry in secondary target excitation mode and in the thin film approach. An incre...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917318

    authors: Caniglia G,Calliari I,Celin L,Tollardo AM

    更新日期:1994-10-01 00:00:00

  • Mercury from maternal "silver" tooth fillings in sheep and human breast milk. A source of neonatal exposure.

    abstract::Neonatal uptake of mercury (Hg) from milk was examined in a pregnant sheep model, where radioactive mercury (Hg203)/silver tooth fillings (amalgam) were newly placed. A crossover experimental design was used in which lactating ewes nursed foster lambs. In a parallel study, the relationship between dental history and b...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02785388

    authors: Vimy MJ,Hooper DE,King WW,Lorscheider FL

    更新日期:1997-02-01 00:00:00

  • Regional distribution of metallothionein and zinc in the mouse gut: comparison with metallothionien-null mice.

    abstract::Gut Zn homeostatic responses to low, replete, and excess dietary Zn (10, 150, and 400 mg Zn/kg, respectively) were compared in mice with (MT+/+) and without (MT-/-) metallothionein (MT) expression. MT concentrations decreased progressively from stomach (12.9 nmol Cd bound/g) to colon (4.6 nmol Cd bound/g). Small intes...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02778942

    authors: Tran CD,Butler RN,Philcox JC,Rofe AM,Howarth GS,Coyle P

    更新日期:1998-09-01 00:00:00

  • Positive PCNA and Ki-67 Expression in the Testis Correlates with Spermatogenesis Dysfunction in Fluoride-Treated Rats.

    abstract::The present study aimed to evaluate the effect of fluoride (F) on spermatogenesis in male rats. F- at 50 and 100 mg/L was administered for 70 days, after which the testicular and epididymis tissues were collected to observe the histopathological structure under a light microscope. The ultrastructure of the testis and ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1338-6

    authors: Zhao WP,Wang HW,Liu J,Tan PP,Luo XL,Zhu SQ,Chen XL,Zhou BH

    更新日期:2018-12-01 00:00:00

  • Cytotoxicity of zinc chloride in mice in vivo.

    abstract::Intraperitoneal administration of zinc chloride (ZnCl2) to Swiss albino mice in vivo induced a significant (p less than or equal to 0.05) increase in the frequencies of chromosomal aberrations of the bone-marrow cells at all concentrations used following acute (7.5, 10, 15 mg/kg body weight) and chronic (2.0, 3.0 mg/k...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02990346

    authors: Gupta T,Talukder G,Sharma A

    更新日期:1991-08-01 00:00:00