Abstract:
:Intraperitoneal administration of zinc chloride (ZnCl2) to Swiss albino mice in vivo induced a significant (p less than or equal to 0.05) increase in the frequencies of chromosomal aberrations of the bone-marrow cells at all concentrations used following acute (7.5, 10, 15 mg/kg body weight) and chronic (2.0, 3.0 mg/kg body wt) treatment. The degree of clastogenicity was directly proportional to the concentrations (p less than or equal to 0.05, trend test) and indirectly to the period of treatment (p less than or equal to 0.05, ANOVA test). It induced a dose-dependent, statistically significant increase (Mann-Whitney U statistics, Student's t-test) in sperm-head abnormalities. The data designate ZnCl2 as a potent clastogen and as a toxic chemical at the concentrations used.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Gupta T,Talukder G,Sharma Adoi
10.1007/BF02990346subject
Has Abstractpub_date
1991-08-01 00:00:00pages
95-101issue
2eissn
0163-4984issn
1559-0720journal_volume
30pub_type
杂志文章abstract::Zinc (Zn) is essential for development, growth, and reproduction. The Mexican government subsidizes micronutrient-fortified milk for risk groups, with positive effect on the targeted groups' plasma Zn level, inferring a good absorption is achieved although it has not being measured. The aim of this study was to determ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0356-x
更新日期:2015-11-01 00:00:00
abstract::The onset of Alzheimer's disease has been shown to affect trace element concentrations in the brain when compared to "normal" subjects in ex vivo samples. The techniques used to determine trace element concentrations were proton-induced X-ray emission and instrumental neutron activation analysis. With these methods, s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784242
更新日期:1999-01-01 00:00:00
abstract::Recently, considerable attention has been paid to the negative effects caused by the presence and constant increase in concentration of heavy metals in the environment, as well as to the determination of their content in human biological samples. In this paper, the concentration of chromium in samples of blood and int...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1328-8
更新日期:2018-12-01 00:00:00
abstract::In this study, a solid-phase extraction method combined with atomic absorption spectrometry for extraction, preconcentration, and determination of iron (Fe(3+)), copper (Cu(2+)), and lead (Pb(2+)) ions at trace levels in water samples has been reported. The influences of effective parameters such as flow rate, pH, elu...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9171-1
更新日期:2012-02-01 00:00:00
abstract::Silicon (Si) is important for the growth and development of bone and connective tissues. Several studies have reported that Si supplementation improved bone mineral density (BMD) in female ovarectomized rats. However, few studies have investigated the effects of Si supplementation on bone status and bone metabolism in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9936-4
更新日期:2014-05-01 00:00:00
abstract::The experiment was conducted to investigate the protective effects of different sources of maternal selenium (Se) on oxidative stressed chick embryo. A total of 270 Lingnan Yellow broiler breeders were randomly allocated into three treatments with five replicates for 18 birds each. Breeders were fed with basal diet (B...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-015-0541-y
更新日期:2016-07-01 00:00:00
abstract::Vanadium compounds maintain euglycemic effects in diabetic rats long after drug withdrawal and bis(α-furancarboxylato)oxovanadium(IV) (BFOV) possesses potent antidiabetic effects in diabetic rats. Here, we investigated the treatment and posttreatment effects of BFOV in diabetic Kuo Kondo [1, 2] with Ay gene (KKAy) mic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9689-5
更新日期:2013-06-01 00:00:00
abstract::Analysis of variance, analysis of covariance, correlation coefficient, multiple correlation, and partial correlation coefficient statistical tests were applied to Cs, Cr, Co, Fe, Rb, Sc, Se, and Zn content in human ovaries in order to evaluate statistically the possible relationships between these trace elements at: t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784090
更新日期:1996-04-01 00:00:00
abstract::Interaction of elements in the course of element uptake by carrot (Daucas carota cv. U.S. harumakigosun) exerted by the addition of elements, such as Rb, Zn, and Al, was investigated. For the purpose of precise evaluation of uptake behavior, the simultaneous determination of absorption of Na, Be, Sr, Mn, Co, Zn, Ce, P...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:84:1-3:197
更新日期:2001-01-01 00:00:00
abstract::In the article, we report that effects of nano-anatase on the spectral characteristics and content of light-harvesting complex II (LHCII) on the thylakoid membranes of spinach were investigated. The results showed that nano-anatase treatment could increase LHCII content on the thylakoid membranes of spinach and the tr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-8025-3
更新日期:2007-01-01 00:00:00
abstract::Wistar male rats were exposed to nickel oxide (NiO) aerosols (mass median aerodynamic diameter, 1.2 μm). The average exposure concentration was controlled from low level (0.6 mg/m(3)) to high level (8.0 mg/m(3)) and total exposure time ranged from 140 to 216 h. Some rats were sacrificed just after the exposure, wherea...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916542
更新日期:1985-02-01 00:00:00
abstract::Lead is a biohazardous metal that is commonly involved in human illness including renal injury. Although it is a non-redox reactive metal, lead-induced renal injury is largely based on oxidative stress. The current work aimed at exploring the possible protective effect of γ-glutamyl cysteine (γGC) against lead-induced...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0624-4
更新日期:2016-09-01 00:00:00
abstract::Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. A cross-sect...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1154-4
更新日期:2018-06-01 00:00:00
abstract::Plasma zinc (Zn) concentrations were measured in 4376 indigent women (86% African-American), at at mean (+/- SD) gestational age of 15 (+/- 7.8) wk to determine the relationship between various maternal characteristics and plasma Zn levels during pregnancy. Mean Plasma An levels were lower in African-American women th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784174
更新日期:1996-10-01 00:00:00
abstract::The primary aim of the research was to assess the level of trace elements and electrolytes in serum of postmenopausal diabetic women. Sixty-four postmenopausal women with type 2 diabetes mellitus (DM2) and 64 age- and body mass index-matched controls were examined. Serum trace elements were assessed using inductively ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0868-z
更新日期:2017-05-01 00:00:00
abstract::Aspirin is widely used as an antiinflammatory drug especially in children with rheumatic fever arthritis. The diminishing effects of aspirin on antioxidant enzymes and hepato-renal systems at high doses are well-known. It is now evident that the damage at antioxidant system worsens the clinical picture of the disease ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8115-x
更新日期:2008-07-01 00:00:00
abstract::The humoral immune response was evaluated in male CD-1 mice fed the iron deficient (7 ppm Fe), iron sufficient (120 ppm Fe), and high-iron diets (3000 or 5000 ppm Fe) for 54 d. The IgM and IgG antibody responses against sheep erythrocytes (SRBC) determined by hemolytic plaque assay were suppressed by 65.4 and 51.2%, r...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790075
更新日期:1994-10-01 00:00:00
abstract::Forty-six elements have been detected in fresh banana pulp purchased weekly in Pittsburgh, PA for the past twelve years (1968-1980). Samples were prepared by lyophilization or low temperature ashing. Analyses were performed using X-ray fluorescence spectrometry, optical emission spectrometry, atomic absorption spectro...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789122
更新日期:1981-03-01 00:00:00
abstract::One hundred and eighty Kunming mice were allotted to three groups in a randomized complete block design, including two treatments and one control. Mice in group 1 were fed a basal diet as control, while mice in groups 2 and 3 were fed the basal diet supplemented with 0.2 mg/kg selenium as sodium selenite (SS) or selen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0243-5
更新日期:2015-06-01 00:00:00
abstract::The purpose of this 42-day study was to investigate the effects of dietary excess vanadium on spleen growth and lesions by determining morphological changes and cell cycle of spleen. Four hundred twenty 1-day-old avian broilers were divided into six groups and fed on a corn-soybean basal diet as control diet or the sa...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8938-0
更新日期:2011-11-01 00:00:00
abstract::The degree of accumulation and distribution of Cd and Pb in the organs of young animals compared to the amount taken in with water or feed have not been thoroughly investigated yet. The experiment aimed to verify whether the source of toxic metals (feed, drinking water) administered to growing rats orally has an influ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0414-4
更新日期:2016-02-01 00:00:00
abstract::A rapid cyclic instrumental neutron activation analysis (CINAA) method has been used to determine the selenium content of 27 duplicate diet samples from each of the 27 districts surrounding Pinhel, Portugal. The accuracy and precision of the CINAA method have been evaluated by analyzing certified reference materials a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992719
更新日期:1990-07-01 00:00:00
abstract::Two trials were conducted in a 2 × 2 + 1 factorial arrangement based on a completely randomized design to evaluate the effects of different sources of selenium (Se) on performance, blood metabolites, and nutrient digestibility in male lambs on a barley-based diet. The first trial lasted for 70 days and consisted of 30...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9698-4
更新日期:2013-07-01 00:00:00
abstract::The metabolic effects of dietary boron, magnesium, and molybdenum on mineral metabolism in the cholecalciferol-deficient chick, with emphasis on growth cartilage histology, were studied. One-day-old cockerel chicks were assigned to groups in a fully-crossed, three factor, 2 x 2 x 2 design. The basal diet was based on ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916650
更新日期:1989-11-01 00:00:00
abstract::Plasma and erythrocyte lipid peroxidation levels of 20 patients with histopathologically confirmed testis cancer and 20 healthy control individuals were studied between November 1995 and June 1997. The group with testis cancer had a mean age of 24.8+/-8.2 yr and the control group's mean age was 28.3+/-6.9 yr. Stage di...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/BTER:73:2:181
更新日期:2000-02-01 00:00:00
abstract::Reversed-phase liquid chromatography-inductively coupled plasma mass spectrometric hyphenation was used for iodine speciation in human serum. First investigations showed that iodine species nearly quantitatively were eluted in the void volume. The result indicated that protein-linked thyroid hormones were not interact...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:78:1-3:81
更新日期:2000-01-01 00:00:00
abstract::The developmental alterations in metallothionein (MT) proteins and zinc (Zn) were investigated in brains of two transgenic strains of mice. MT protein was measured by a cadmium binding assay and Zn by atomic absorption spectrophotometry. MT proteins were expressed at birth (day 1) both in MT-I overexpressing transgeni...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784039
更新日期:1998-01-01 00:00:00
abstract::The consumption of vegetables grown on soils polluted by trace elements can cause a serious threat for animal and human health and disturb the functioning of the ecosystem. The aim of this work is to determine the concentrations of As, Cd, Co, Cr, Cu, Ni, Pb, Mn, and Zn in soils and different vegetables from market ga...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01849-6
更新日期:2020-05-01 00:00:00
abstract::Prescription food for special medical purposes (FSMPs) and modified milk products (MMPs) for babies in the infancy period available in pharmacies are increasingly frequently used for newborns and infants-especially in cases where allergies and food-borne diseases are diagnosed. However, there is a lack of scientific s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01667-w
更新日期:2019-12-01 00:00:00
abstract::Selenium and methylmercuric chloride (MMC) interactions regarding cellular uptake and selenium protection on MMC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with (3.5 or 5 microM) MMC. Cells...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:3:251
更新日期:2001-06-01 00:00:00