Abstract:
:Neonatal uptake of mercury (Hg) from milk was examined in a pregnant sheep model, where radioactive mercury (Hg203)/silver tooth fillings (amalgam) were newly placed. A crossover experimental design was used in which lactating ewes nursed foster lambs. In a parallel study, the relationship between dental history and breast milk concentration of Hg was also examined in 33 lactating women. Results from the animal studies showed that, during pregnancy, a primary fetal site of amalgam Hg concentration is the liver, and, after delivery, the neonatal lamb kidney receives additional amalgam Hg from mother's milk. In lactating women with aged amalgam fillings, increased Hg excretion in breast milk and urine correlated with the number of fillings or Hg vapor concentration levels in mouth air. It was concluded that Hg originating from maternal amalgam tooth fillings transfers across the placenta to the fetus, across the mammary gland into milk ingested by the newborn, and ultimately into neonatal body tissues. Comparisons are made to the U. S. minimal risk level recently established for adult Hg exposure. These findings suggest that placement and removal of "silver" tooth fillings in pregnant and lactating humans will subject the fetus and neonate to unnecessary risk of Hg exposure.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Vimy MJ,Hooper DE,King WW,Lorscheider FLdoi
10.1007/BF02785388subject
Has Abstractpub_date
1997-02-01 00:00:00pages
143-52issue
2eissn
0163-4984issn
1559-0720journal_volume
56pub_type
杂志文章abstract::A working analytical procedure for selenium determinations by INAA, using gamma spectrometry with a germanium well-type detector, is presented. The spectral line at 400.7 keV is employed, enhanced with the effect of energy summing in true coincidence of cascade photons. The main advantage of the method is high efficie...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917304
更新日期:1994-10-01 00:00:00
abstract::Trace element involvement in wounds left to heal by secondary intention needs clarification. We have previously reported faster healing of wounds following acute surgery compared with elective excision of pilonidal sinus disease. The effect of topical zinc on the closure of the excisional wounds was mediocre compared ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9658-z
更新日期:2013-06-01 00:00:00
abstract::Lipid peroxy radicals (ROO.) were detected by electron spin resonance (ESR) at low temperature after formation by addition of H2O2 into a suspension of mice lymphocytes. If lymphocytes were treated with selenomethionine (Se-Met) prior to addition of H2O2, ROO. formation was inhibited in a fashion that was dependent on...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783233
更新日期:1997-01-01 00:00:00
abstract::Selenium (Se) is an essential trace element in animals and human, however, excess Se intake can result in adverse health effects. Se supplementation increased glutathione peroxidase (GSH-Px) and thioredoxin reductase (TR) expressions in Se-deficient rats. However, little information is available on the relationship be...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:89:2:165
更新日期:2002-11-01 00:00:00
abstract::X-ray Fluorescence (XRF) Analysis and Atomic Absorption Spectrophotometry (AAS) have been used in assessing heavy metal pollution from some gold mines in Ghana. The presence and levels of heavy metals in gold ore, gold tailings, inland waters, and river sediments have been determined. Using these techniques, the heavy...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992682
更新日期:1990-07-01 00:00:00
abstract::The effects of 10 wk of selenium (Se) supplementation (5 ppm) in drinking water on immune responses and resistance to a myocarditic Coxsackie virus B3 (CB3) infection were studied in female Balb/c mice. Se supplementation reduced CB3-induced mortality: at day 14 postinoculation, survival was 58% in the Se-treated grou...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785277
更新日期:1998-07-01 00:00:00
abstract::Scleroderma, sclerosis of the skin, is a severe autoimmune disease refractant to all kind of treatments. To study the in vivo effects of a combination of three oligoelements selenium (Se), zinc (Zn), and manganese (Mn) plus Lachesis muta venom (O-LM) on the bleomycin (BLM)-induced scleroderma mouse experimental model....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9876-4
更新日期:2014-02-01 00:00:00
abstract::Concentration of heavy metals (lead (Pb), cadmium (Cd), chromium (Cr), and copper (Cu)) was determined in the liver, gills, kidneys, and muscles of eight edible fish species (Channa punctata, Cirrhinus reba, Labeo rohita, Heteropneustes fossilis, Mystus cavasius, Oreochromis niloticus, Puntius sophore, and Wallago att...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9011-3
更新日期:2011-12-01 00:00:00
abstract::Human serum butyrylcholinesterase (BChE) has been converted into a stable but less active desensitized form when heated at 45 degrees C for 24 h. The desensitized BChE follows Michaelis-Menten kinetics, whereas native enzyme exhibits slightly negative cooperativity with respect to butyrylthiocholine binding. In this s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:93:1-3:55
更新日期:2003-07-01 00:00:00
abstract::Selenium (Se) mainly performs its function through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, plays important roles in the normal function of the heart. To investigate the possible relationship between Se and SelW for the regulation of oxidative damage in chicken embryo myo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0529-7
更新日期:2016-06-01 00:00:00
abstract::This report explains the employing of a combination test of traditional cell culture with a quantitative real-time PCR for assessment of the antiviral effect of zinc sulfate (ZnSO4) on herpes simplex virus (HSV)-infected Vero cells. Our evidence showed that the treatment with 0.3 mM ZnSO4 strongly inhibited the replic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01728-0
更新日期:2020-02-01 00:00:00
abstract::Zinc uptake regulator (Zur) is a negative transcriptional regulator of bacteria that belongs to the FUR superfamily of proteins and regulates zinc (Zn) homeostasis under extreme Zn conditions. The Zur protein of Bacillus anthracis (BaZur) was though characterized previously, but the residues of this transcriptional re...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02427-x
更新日期:2020-10-14 00:00:00
abstract:UNLABELLED:Limited data are available indicating the effects of chromium administration on endocrine profiles, biomarkers of inflammation, and oxidative stress among women with polycystic ovary syndrome (PCOS). This study was done to assess the effects of chromium administration on endocrine profiles, biomarkers of inf...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-015-0570-6
更新日期:2016-07-01 00:00:00
abstract::It has been demonstrated that zinc exerts its beneficial influence on skin fibroblasts. Propolis, a complex mixture of plant-derived and bees' products, was reported to stimulate cicatrization processes in skin and prevent infections. The aim of this study was to find out how zinc and propolis influence human skin fib...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0019-3
更新日期:2014-07-01 00:00:00
abstract::A dietary requirement is defined as the lowest continuing intake of a nutrient that for a specified indicator of adequacy, will maintain a defined level of nutriture in an individual. An essential dietary component is one that the body cannot synthesize in sufficient quantities to maintain health. Recommended dietary ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783138
更新日期:1998-01-01 00:00:00
abstract::Studies of effects of diazepam on liver parenchyma are very scanty. In this study, adult albino rats were treated with diazepam in two different doses (0.25 mg and 0.30 mg/kg body wt) daily for 30 and 60 d. Through light microscopy and electron microscopy, prenecrotic and necrotic changes were noted in the high-dose g...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785292
更新日期:1997-06-01 00:00:00
abstract::Selenium concentrations in the blood of 112 (56 females and 56 males) normal subjects, from different regions of the Punjab (Pakistan), have been determined using the technique of inductively coupled plasma-mass spectrometry. The whole blood selenium concentrations were found to be 452 ± 12 ppb (parts per billion or n...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8867-y
更新日期:2011-10-01 00:00:00
abstract::Biotransformation of inorganic arsenic in mammals is catalyzed by three serial enzyme activities: arsenate reductase, arsenite methyltransferase, and monomethylarsonate methyltransferase. Our laboratory has purified and characterized these enzymes in order to understand the mechanisms and elucidate the variations of t...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/BF02783907
更新日期:1999-06-01 00:00:00
abstract::Iron and copper are essential microminerals that are intimately related. The present study was performed to determine the effect of iron-deficiency anemia (IDA) and treatment with iron on laboratory indicators of copper status. Hemoglobin, mean corpuscular volume erythrocyte Zn protoporphyrin, serum ferritin, serum co...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:112:3:213
更新日期:2006-09-01 00:00:00
abstract::This study was focused on the analysis of arsenic (As) levels in scalp hair of children (age, <10 years) collected from two towns of Khairpur, Pakistan, to evaluate the effects of As-contaminated groundwater. For comparative purposes, scalp hair samples of children were also collected from that area having low levels ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8866-z
更新日期:2011-10-01 00:00:00
abstract::To investigate the protective effect of garlic powder on cadmium-induced toxicity sea bass liver, juvenile fishes where maintained under three food diets (diet 1: normal without garlic supply, diet 2: 2% garlic powder; diet 3: 6% garlic powder). After 30 days of specific diets, each group was injected with 500 μg kg-1...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1146-4
更新日期:2018-06-01 00:00:00
abstract::Severe hyperhomocysteinemia (HHC) is associated with atherosclerosis. In hemodialysis (HD) patients, one of the main causes of death is cardiovascular disease. In animals, trace elements such as cobalt, copper, iron, and nickel ameliorated vitamin B(12) deficiency-induced HHC. However, correlations between plasma tota...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8139-2
更新日期:2008-09-01 00:00:00
abstract::In subjects with impaired insulin action, alterations of the serum sodium and potassium concentrations have been reported. The resulting cationic imbalance, along with the osmotic effect of the elevated sugar levels, could influence the course of diabetes mellitus management. Therefore, this study was conducted to com...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-011-9144-4
更新日期:2011-12-01 00:00:00
abstract::The purpose of current study was to determine the step at which dietary selenium (Se) regulates the transcriptional expression of the gene for Se-glutathione peroxidase (Se-GPx) in rat brain and transplanted glioma tissue. Wistar rats were fed a Se-free diet or the same diet supplemented with 0.5, 2.0, and 4.0 mg Se/k...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:73:1:67
更新日期:2000-01-01 00:00:00
abstract::Neutron activation analysis (NAA) methodology was applied for the certification of eight trace elements (As, Co, Cr, Cu, Hg, Mn, Se, and Zn) in a plankton reference material (CRM 414) prepared by the BCR of the Commission of the European Communities. Average concentrations (micrograms/g dry wt) and standard deviations...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917365
更新日期:1994-10-01 00:00:00
abstract::Selenium exerts many, if not most, of its physiological functions as a selenocysteine moiety in proteins. Selenoproteins are involved in many biochemical processes including regulation of cellular redox state, calcium homeostasis, protein biosynthesis, and degradation. A neurodevelopmental syndrome called progressive ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9920-z
更新日期:2014-05-01 00:00:00
abstract::Various studies indicate the role of manganese (Mn) in the virulence of pathogens. Salmonella is an intracellular pathogen which is able to multiply within the macrophages. The present study was therefore, designed to assess the effect of Mn supplementation on Salmonella-macrophage interactions particularly in referen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8406-x
更新日期:2010-01-01 00:00:00
abstract::Lack of specific markers constitutes a problem during diagnosis of headache syndromes. Recently, some metals have gained importance as biological parameters for the diagnosis and during treatment. Low-ionized Mg and high-ionized Ca/Mg in patients with daily migrainous headaches were noted. The blood Na level was shown...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1385/BTER:90:1-3:1
更新日期:2002-01-01 00:00:00
abstract::The effect ofin utero zinc deficiency on fetal development in rats is reviewed. Attention is paid to the primary biochemical lesion associated with zinc-related teratogenesis and special consideration is given to the central nervous system. Evidence is presented that the thymidine kinase salvage pathway, used for the ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916569
更新日期:1985-03-01 00:00:00
abstract::Bulk fabrication of ordered hollow structural particles (HSPs) with large surface area and high biocompatibility simultaneously is critical for the practical application of HSPs in biosensing and drug delivery. In this article, we describe a smart approach for batch synthesis of calcium carbonate nanotubes (CCNTs) bas...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9325-9
更新日期:2012-06-01 00:00:00