Hepatotoxicity of diazepam. Structural and trace metal studies in rat.

abstract：:Zinc has been reported to enhance the response to interferon (IFN) or PEG-IFN plus ribavirin therapy, improve liver function, and ameliorate hematologic side effects in patients with chronic hepatitis C. However, the role of zinc supplementation during IFN therapy in chronic hepatitis B infection (CHB) remains unclear...

journal_title：Biological trace element research

authors： Kuloğlu Z,Kırbaş G,Erden E,Kansu A

更新日期：2011-12-01 00:00:00

abstract：:Tomato quality and its potential health benefits are directly related to its chemical composition. The characterization of nutritional properties of Solanum germplasm is essential to choose suitable donor parents for breeding programs. In this sense, wild species could be very useful for tomato fruit quality genetic i...

journal_title：Biological trace element research

authors： Fernández-Ruiz V,Olives AI,Cámara M,Sánchez-Mata Mde C,Torija ME

更新日期：2011-06-01 00:00:00

abstract：:The present study aimed to evaluate the effect of fluoride (F) on spermatogenesis in male rats. F- at 50 and 100 mg/L was administered for 70 days, after which the testicular and epididymis tissues were collected to observe the histopathological structure under a light microscope. The ultrastructure of the testis and ...

journal_title：Biological trace element research

authors： Zhao WP,Wang HW,Liu J,Tan PP,Luo XL,Zhu SQ,Chen XL,Zhou BH

更新日期：2018-12-01 00:00:00

abstract：:The effects of dietary sodium selenite and vitamin E on the microvascular permeability of rat organs such as heart, brain, kidney, liver and eye were investigated by using the Evans blue leakage method. Combined deficiency of selenium and vitamin E caused an increase in the permeability of the heart and eye with respe...

journal_title：Biological trace element research

authors： Demirel-Yilmaz E,Dinçer D,Yilmaz G,Turan B

更新日期：1998-07-01 00:00:00

abstract：:The present study was designed to investigate the effect of mercuric chloride administration on copper, zinc, and iron concentrations in the liver, kidney, lung, heart, spleen, and muscle of rats. The results showed that after dose and time exposure to mercuric chloride, the concentration of mercury in the six tissues...

journal_title：Biological trace element research

authors： Huang YL,Lin TH

更新日期：1997-07-01 00:00:00

abstract：:Many studies have shown that zinc deficiency could decrease the response to insulin. In genetically diabetic animals, a low zinc status has been observed contrary to induced diabetic animals. The zinc status of human patients depends on the type of diabetes and the age. Zinc supplementation seems to have beneficial ef...

journal_title：Biological trace element research

authors： Faure P,Roussel A,Coudray C,Richard MJ,Halimi S,Favier A

更新日期：1992-01-01 00:00:00

abstract：:Studies were performed on adult and fetal rats receiving either a zinc-deficient (<0.5 ppm) diet and/or ethanol (20%) throughout pregnancy. Liver zinc levels were depressed in fetuses exposed toin utero zinc deficiency, but brain zinc levels were unchanged. Ethanol had no effect on the concentration of zinc in the sev...

journal_title：Biological trace element research

authors： Dreosti IE,Partick EJ

更新日期：1987-12-01 00:00:00

abstract：:In vivo and in vitro studies were conducted to investigate the chemical forms by ion-exchange chromatography of selenium (Se) present in rat and ovine spermatozoa. After injection with 75Se-selenite, the form of 75Se in rat sperm was selenocysteine, but selenocysteine and selenomethionine (SeMet) were present in ovine...

journal_title：Biological trace element research

authors： Alabi NS,Beilstein MA,Whanger PD

更新日期：2000-08-01 00:00:00

abstract：:Free oxygen radicals and insufficient antioxidant enzymes have been implicated in the pathogenesis of hypercholesterolemia (HC). Trace elements function as cofactors in antioxidant enzymes. Antioxidant system and trace elements were investigated in many different studies including HC, but these subjects have not been ...

journal_title：Biological trace element research

authors： Yilmaz MI,Baykal Y,Kilic M,Sonmez A,Bulucu F,Aydin A,Sayal A,Kocar IH

更新日期：2004-05-01 00:00:00

abstract：:The main aim of the study was to determine the role of cerium in the amelioration of calcium-deficiency effects in spinach plants. Spinach plants were cultivated in Hoagland's solution. They were subjected to calcium-deficiency and to cerium chloride administered in the calcium-present Hoagland's media and calcium-def...

journal_title：Biological trace element research

authors： Chao L,Bofu P,Weiqian C,Yun L,Hao H,Liang C,Xiaoqing L,Xiao W,Fashui H

更新日期：2008-03-01 00:00:00

abstract：:Recently, considerable attention has been paid to the negative effects caused by the presence and constant increase in concentration of heavy metals in the environment, as well as to the determination of their content in human biological samples. In this paper, the concentration of chromium in samples of blood and int...

journal_title：Biological trace element research

authors： Dudek-Adamska D,Lech T,Konopka T,Kościelniak P

更新日期：2018-12-01 00:00:00

abstract：:Since chromium(VI) is unreactive toward DNA under physiological conditions in vitro, the ability of carcinogenic chromium(VI) compounds to damage DNA depends on the presence of cellular redox components that reduce chromium(VI) to reactive species capable of interacting with DNA. We have examined the role of glutathio...

journal_title：Biological trace element research

authors： Wetterhahn KE,Hamilton JW,Aiyar J,Borges KM,Floyd R

更新日期：1989-07-01 00:00:00

abstract：:Selenium is a trace element that, although toxic in higher concentrations, is essential for human and animal health. In this study, we looked at microarray-based gene expression patterns from liver and gastrocnemius tissues in mice fed either a selenium-deficient diet or diets containing sodium selenite, selenomethion...

journal_title：Biological trace element research

authors： Mallonee DH,Crowdus CA,Barger JL,Dawson KA,Power RF

更新日期：2011-11-01 00:00:00

abstract：:In subjects with impaired insulin action, alterations of the serum sodium and potassium concentrations have been reported. The resulting cationic imbalance, along with the osmotic effect of the elevated sugar levels, could influence the course of diabetes mellitus management. Therefore, this study was conducted to com...

journal_title：Biological trace element research

authors： Al-Rubeaan K,Siddiqui K,Abu Risheh K,Hamsirani R,Alzekri A,Alaseem A,Saleh SM,Al-Yami Z,Al-Ghamdi A,Alayed K

更新日期：2011-12-01 00:00:00

abstract：:This in vitro study was designed to assess the impact of divalent (Fe(2+)) or trivalent (Fe(3+)) iron on the activity and oxidative balance of bovine spermatozoa at specific time intervals (0, 2, 8, 16, and 24 h) during an in vitro culture. Forty-five semen samples were collected from adult breeding bulls and diluted ...

journal_title：Biological trace element research

authors： Tvrdá E,Lukáč N,Lukáčová J,Jambor T,Massányi P

更新日期：2015-09-01 00:00:00

abstract：:In zinc deficiency, the function of leukocytes is impaired. However, the results of studies on the zinc concentration of blood cells in zinc deficiency are conflicting, probably in part because of technical and analytical problems. The aim of this study was to investigate, under standard conditions, the uptake of 65Zn...

journal_title：Biological trace element research

authors： Naber TH,van den Hamer CJ,van den Broek WJ,van Tongeren JH

更新日期：1992-11-01 00:00:00

abstract：:An external-sample liquid scintillation (LS) counting for the gamma emitter 75Se has been developed. An expressly designed well-type LS vial and a 2,5-diphenyoxazole-1,4-bis(5-phenyl-2-oxazoyl)-benzene-xylene solution containing 35% tertrabutylzinn allow 75Se to be counted in a standard LS counter with counting effici...

journal_title：Biological trace element research

authors： Qu XH,Huang KX,Wu ZX,Zhong S,Deng LQ,Xu HB

更新日期：2000-12-01 00:00:00

abstract：:The effect ofin utero zinc deficiency on fetal development in rats is reviewed. Attention is paid to the primary biochemical lesion associated with zinc-related teratogenesis and special consideration is given to the central nervous system. Evidence is presented that the thymidine kinase salvage pathway, used for the ...

journal_title：Biological trace element research

authors： Dreosti IE,Record IR,Manuel SJ

更新日期：1985-03-01 00:00:00

abstract：:The aim of this study was to investigate the protective effects of erdosteine and vitamins C and E (VCE) on the lungs after performing hind limb ischemia-reperfusion (I/R) by assessing oxidative stress, plasma copper (Cu), and zinc (Zn) analysis. The animals were divided randomly into four groups as nine rats each as ...

journal_title：Biological trace element research

authors： Sirmali M,Uz E,Sirmali R,Kilbaş A,Yilmaz HR,Altuntaş I,Naziroğlu M,Delibaş N,Vural H

更新日期：2007-07-01 00:00:00

abstract：:Selenium is a trace element that has antioxidant and neuroprotective effects. The aim of this study is to investigate the effects of selenium in reducing ischemia-reperfusion injury of the gastrocnemius muscle. In this experimental study, 80 adult male Wistar rats weighing 250-300 g were divided into ten groups (N = 8...

journal_title：Biological trace element research

authors： Gholami M,Zendedel A,Khanipour khayat Z,Ghanad K,Nazari A,Pirhadi A

更新日期：2015-04-01 00:00:00

abstract：:Samples of Evernia prunastri, collected in a mountainous zone, were exposed in urban and highly industrialized areas in order to monitor the atmospheric pollution. Amounts of Cr, Mn, Fe, Ni, Cu, Zn, and Pb were determined by EDXRF spectrometry in secondary target excitation mode and in the thin film approach. An incre...

journal_title：Biological trace element research

authors： Caniglia G,Calliari I,Celin L,Tollardo AM

更新日期：1994-10-01 00:00:00

abstract：:Selective actinide ion recovery from dilute, aqueous, multication waste streams is an important problem. The recovery of uranium (U) and thorium (Th) by various animal biopolymers was examined. Of four species of biopolymers tested, a high uptake of uranium and thorium was found in hen eggshell membrane (ESM) and silk...

journal_title：Biological trace element research

authors： Ishikawa S,Suyama K,Arihara K,Itoh M

更新日期：2002-06-01 00:00:00

abstract：:The toxic effect of Pb2+ has been studied in eukaryotic cells by using Tetrahymena as a target. The maximum power (P(m)) and the growth rate constant (k) were determined, which showed that values of P(m) and k were linked to the concentration (C) of Pb2+. The addition of Pb2+ caused a decrease of the maximum heat prod...

journal_title：Biological trace element research

authors： Peng L,Weiying Z,Xi L,Xiaojuan C,Chaocan Z

更新日期：2007-11-01 00:00:00

abstract：:Several studies have investigated the relationship between serum Se concentration and cervical cancer, but the results were inconsistent. Thus, we conducted a systematic review and meta-analysis to evaluate the association between serum selenium levels and cervical cancer. Twelve studies investigating the association ...

journal_title：Biological trace element research

authors： He D,Wang Z,Huang C,Fang X,Chen D

更新日期：2017-10-01 00:00:00

abstract：:Fluoride (F) concentration in blood serum of healthy dromedary camel population was measured, and its relationship with age and sex was determined. In male animals, the level varied from 0.017 to 0.296 ppm, with mean (± S.E.) value of 0.163 ± 0.013 ppm. In females, the level varied from 0.036 to 0.372 ppm with mean va...

journal_title：Biological trace element research

authors： Ranjan A,Nabi J,Ranjan R

更新日期：2021-01-06 00:00:00

abstract：:Reversed-phase liquid chromatography-inductively coupled plasma mass spectrometric hyphenation was used for iodine speciation in human serum. First investigations showed that iodine species nearly quantitatively were eluted in the void volume. The result indicated that protein-linked thyroid hormones were not interact...

journal_title：Biological trace element research

authors： Michalke B,Schramel P,Witte H

更新日期：2000-01-01 00:00:00

abstract：:Iodine, an essential micronutrient, is required to produce thyroid hormones. Iodine deficiency disorders (IDD) comprise a range of adverse maternal and fetal outcomes, with the most significant irreversible effect resulting from neurodevelopmental deficits in fetal brain caused by deficient iodine status during early ...

journal_title：Biological trace element research

authors： Panth P,Guerin G,DiMarco NM

更新日期：2019-03-01 00:00:00

abstract：:The present study was designed to investigate the effects of montmorillonite (MMT) on dietary Cd-induced oxidative damage in liver and kidney of carp (Carassius auratus). One hundred eighty carp were randomly divided into four groups and fed with a basal diet, a basal diet supplemented with 0.5% MMT, Cd-comtaminated b...

journal_title：Biological trace element research

authors： Kim SG,Dai W,Xu Z,Li G

更新日期：2011-06-01 00:00:00

abstract：:Obesity is a major public health problem worldwide and a risk factor for certain diseases, including cardiovascular disease, diabetes, cancer, and depression. Unfortunately, currently available anti-obesity drugs have failed in the long-term maintenance of weight control. It has been a challenge to design novel drugs ...

journal_title：Biological trace element research

authors： Yilmaz AB,Tapsin S,Elbasan EB,Kayhan HD,Sahin F,Turkel N

更新日期：2020-02-01 00:00:00

abstract：:The aim of the present study was to evaluate the oxidative stress level and antioxidant trace elements status associated with lower airway disease in draft horses. For this purpose, venous blood samples were obtained from draft horses exhibiting signs of lower respiratory tract disorders (n = 83) and from control grou...

journal_title：Biological trace element research

authors： Youssef MA,El-Khodery SA,Ibrahim HM

更新日期：2012-12-01 00:00:00