Abstract:
:Several studies have investigated the relationship between serum Se concentration and cervical cancer, but the results were inconsistent. Thus, we conducted a systematic review and meta-analysis to evaluate the association between serum selenium levels and cervical cancer. Twelve studies investigating the association by univariate analysis and five studies by multivariate analysis were identified after a systematic search of PubMed, Wanfang, CNKI, and SinoMed databases. Standard mean differences (SMD) or odds ratios (OR) with the corresponding 95% confidence intervals (CI) were pooled to compare the selenium levels between different groups. In univariate analysis, serum selenium levels in cervical cancer cases were significantly lower than in controls (SMD = -4.86, 95% CI -6.03-3.69). Subgroup analysis showed consistent results. In multivariate analysis, serum selenium levels in cervical cancer cases were also significantly lower than in controls (OR = 0.55, 95% CI 0.42-0.73). After treatment, the serum selenium levels increased significantly (SMD = 2.59, 95% CI 0.50-4.69). In conclusion, high serum selenium levels were associated with cervical cancer, and selenium exposure might be a protective factor for cervical cancer.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
He D,Wang Z,Huang C,Fang X,Chen Ddoi
10.1007/s12011-017-0982-6subject
Has Abstractpub_date
2017-10-01 00:00:00pages
195-202issue
2eissn
0163-4984issn
1559-0720pii
10.1007/s12011-017-0982-6journal_volume
179pub_type
杂志文章,meta分析abstract::Recently, several attempts have been made to use the phytopharmaceuticals from plant extracts as reducing, capping and stabilizing agents for the biomimetic synthesis of various metal nanoparticles conjugated to the phytopharmaceuticals. These biogenic metal nanoparticles are non-toxic and can be used as contrast agen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1287-0
更新日期:2018-11-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9158-y
更新日期:2012-01-01 00:00:00
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journal_title:Biological trace element research
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doi:10.1007/s12011-018-1338-6
更新日期:2018-12-01 00:00:00
abstract::An in vitro system employing collagen isolated from the sheep tendons to induce mineralization and demineralization reactions was used not only to study the effect of various concentrations of fluoride on the collagen-induced mineralization and demineralization reactions but also to compare their action with the inhib...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02340-3
更新日期:2020-08-27 00:00:00
abstract::This work is a first attempt to determine the speciation of Cr in human plasma. With the aid of in vitro and in vivo 51Cr-labeled experiments, it was possible to develop the necessary biochemical techniques for the separation of the plasma proteins. Further work will use real samples, taking care to avoid contaminatio...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992700
更新日期:1990-07-01 00:00:00
abstract::Nickel is an important kind of metal and a necessary trace element in people's production and livelihood; it is also a well-confirmed human carcinogen. In the past few years, researchers did a large number of studies about the molecular mechanisms of nickel carcinogenesis, and they focused on activation of proto-oncog...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9619-6
更新日期:2013-05-01 00:00:00
abstract::The onset of Alzheimer's disease has been shown to affect trace element concentrations in the brain when compared to "normal" subjects in ex vivo samples. The techniques used to determine trace element concentrations were proton-induced X-ray emission and instrumental neutron activation analysis. With these methods, s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784242
更新日期:1999-01-01 00:00:00
abstract::The present study was undertaken to evaluate methylmercury-induced alterations in hepatic enzymes and oxidative stress markers in liver tissue of rainbow trout (Oncorhynchus mykiss) by using a perfusion method, and to explore possible protective effect of vitamin C against these alterations. Forty-eight fish were divi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0241-7
更新日期:2015-05-01 00:00:00
abstract::Studies of effects of diazepam on liver parenchyma are very scanty. In this study, adult albino rats were treated with diazepam in two different doses (0.25 mg and 0.30 mg/kg body wt) daily for 30 and 60 d. Through light microscopy and electron microscopy, prenecrotic and necrotic changes were noted in the high-dose g...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785292
更新日期:1997-06-01 00:00:00
abstract::The structure and bioactivity of Ginkgo biloba leaves polyprenol (GBP) are similar to that of dolichol which widely exists in human and mammalian organs. GBP possesses potential pharmacological activities against cancer. This study involved oil-in-water type nanoemulsion (NE) loading GBP was prepared by dissolving pol...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1184-y
更新日期:2018-07-01 00:00:00
abstract::Since waterborne minerals appear in ionic form and are readily absorbed by the gastrointestinal tract, drinking water could be a crucial source of mineral intake. However, no comprehensive research has yet determined how trace elements in drinking water relate to body composition. We aimed to assess the relationship b...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-016-0779-z
更新日期:2017-02-01 00:00:00
abstract::Issues regarding biomagnification of mercury (Hg) due to its persistence, bioaccumulation, and toxicity in freshwater lakes have gained much attention in the last two decades especially in remote regions of the world where anthropogenic inputs are considered as negligible. In this study, spatial distribution of total ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02479-z
更新日期:2021-01-07 00:00:00
abstract::We investigated the effects of zinc supplementation in case of moderate growth retardation in which GH treatment could not be used. Zamic (ZA, an association containing arginine, L-methionine, and zinc; from Aguettant pharmaceuticals) was compared with arginine aspartate (AA) (5 g) in a crossover randomized trial (6 m...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02789076
更新日期:1995-04-01 00:00:00
abstract::This study evaluated the plasma levels of trace elements in children with chronic hepatitis B virus (HBV) infection and assessed whether they can be a factor that affects the response to interferon alpha (IFN-alpha) treatment. The study included 35 cases (ten girls, 25 boys) aged 3-13 years with chronic HBV infection ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8507-6
更新日期:2010-06-01 00:00:00
abstract::The current study was conducted in order to investigate the short-term effects (6, 12, and 24 h) of silicon (Si) on the endogenous hormonal composition of rice (Oryza sativa L. cv. Dongjin-beyo), with and without wounding stress. Si applied in different concentrations (0.5, 1.0, and 2.0 mM) significantly promoted shoo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9047-4
更新日期:2011-12-01 00:00:00
abstract::Methylmercury (MeHg) is highly toxic, and its principal target tissue in human is the nervous system, which has made MeHg intoxication a public health concern for many decades. Portulaca oleraceae (purslane), a member of the Portulacaceae family, is widespread as a weed and has been ranked the eighth most common plant...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0546-6
更新日期:2016-07-01 00:00:00
abstract::Although coenzyme Q10 (CoQ10) is a component of the oxidative phosphorylation process in mitochondria that converts the energy in carbohydrates and fatty acids into ATP to drive cellular machinery and synthesis, its effect in type I diabetes is not clear. We have studied the effect of 4 wk of treatment with CoQ10 (10 ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:109:1:025
更新日期:2006-01-01 00:00:00
abstract::Pituitary dwarfism (hGHD) is known to be associated with trace element deficiency, which causes improper functioning of the involved endocrine system. Previously, we reported on the head hair concentrations of zinc, copper, manganese, and iron from a total of 418 normal subjects (154 male and 264 female). In this repo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:85:2:127
更新日期:2002-02-01 00:00:00
abstract::Metabolic alterations and inflammation are regarded as hallmarks of cancer. Glycolytic flux and intermediate accumulation lead to the production of building blocks and NADPH which is important in protecting the cell from oxidative damage. Inflammation causes the release of mediators responsible for regulating molecula...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02363-w
更新日期:2020-09-03 00:00:00
abstract::This study was conducted to investigate the effect of zinc chitosan chelate (CS-Zn) on zinc transporter expression and content of tissue zinc in weaned piglets. A total of 90 weaned pigs (Duroc × Landrace × Yorkshire) were randomly allocated to treatment groups with supplementation of 100 mg/kg zinc as ZnSO4, 100 mg/k...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0732-1
更新日期:2016-12-01 00:00:00
abstract::Selenium and methylmercuric chloride (MMC) interactions regarding cellular uptake and selenium protection on MMC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with (3.5 or 5 microM) MMC. Cells...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:3:251
更新日期:2001-06-01 00:00:00
abstract::Aluminum (Al) absorption seems to be very low, but many factors can enhance it in animals and humans. In the present study, we investigated the acute effect of Na citrate on Al absorption by monitoring Al levels in blood and several tissues. For this purpose, 18 Wistar male rats were divided into 3 groups: control, Al...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02778873
更新日期:1998-08-01 00:00:00
abstract::The humoral immune response was evaluated in male CD-1 mice fed the iron deficient (7 ppm Fe), iron sufficient (120 ppm Fe), and high-iron diets (3000 or 5000 ppm Fe) for 54 d. The IgM and IgG antibody responses against sheep erythrocytes (SRBC) determined by hemolytic plaque assay were suppressed by 65.4 and 51.2%, r...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790075
更新日期:1994-10-01 00:00:00
abstract::Several authors have already underlined chromium implication in glucose and lipids metabolism of humans. In this field, physiological chromium determination in serum could be helpful, but the discrepancies reported in numerous papers are confusing. Here we report some results obtained by Zeeman correction Graphite Fur...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784591
更新日期:1992-01-01 00:00:00
abstract::Naphthalene-1-acetic acid (HNAA), dichlorophenoxy acetic acid (HDAA), and indole-3-acetic acid (HIAA) are auxinhormones that can affect the growth of plants. The lanthanide complexes of the above auxinhormone LnA3 x 3H2O (Ln = La3+, Ce3+, Sm3+, Er3+, Yb3+; HA = HNAA, HDAA, HIAA; A = NAA-, DAA-, IAA-) were synthesized ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783322
更新日期:1998-07-01 00:00:00
abstract::Nickel (Ni) has not been elucidated as an essential mineral in dairy animals, though in plants and lower organisms, its role in activation of urease enzyme is well known. This study was conducted to evaluate the effect of Ni supplementation on intake, growth performance, urease activity, antioxidant and immune status,...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1524-6
更新日期:2019-07-01 00:00:00
abstract::Copper is an integral part of many important enzymes involved in a number of vital biological processes. Even though it is essential to life, at elevated tissue concentrations, copper can become toxic to cells. Recent studies have reported oxidative damage due to copper in various tissues. Considering the vulnerabilit...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9320-1
更新日期:2012-06-01 00:00:00
abstract::Dietary Reference Intakes are not yet established for boron (B), a naturally occurring trace element in the human diet. Estimated dietary B intakes provide useful information for planning and assessing diets in healthy populations. The countries selected for this study represent a wide variety of dietary patterns and ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783128
更新日期:1998-01-01 00:00:00
abstract::The kidney has been regarded as a critical organ of toxicity induced by acute exposure to hexavalent chromium [Cr(VI)] compounds. Reactive intermediates and free radicals generated during reduction process might be responsible for Cr(VI) toxicity. In this study, the effects of pretreatment or posttreatment of taurine ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:102:1-3:209
更新日期:2004-01-01 00:00:00
abstract::Interaction of elements in the course of element uptake by carrot (Daucas carota cv. U.S. harumakigosun) exerted by the addition of elements, such as Rb, Zn, and Al, was investigated. For the purpose of precise evaluation of uptake behavior, the simultaneous determination of absorption of Na, Be, Sr, Mn, Co, Zn, Ce, P...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:84:1-3:197
更新日期:2001-01-01 00:00:00