Abstract:
:An in vitro system employing collagen isolated from the sheep tendons to induce mineralization and demineralization reactions was used not only to study the effect of various concentrations of fluoride on the collagen-induced mineralization and demineralization reactions but also to compare their action with the inhibitors of mineralization and/or demineralization. Studies demonstrated that under physiological conditions, at lower concentrations (5 × 10-6 to 5 × 10-5 M) fluoride inhibited while at higher concentrations (> 10-4 M), it stimulated the collagen-induced in vitro mineralization. At higher concentrations, fluoride was also found to inhibit the demineralization of the collagen bound preformed mineral phase. At low concentrations, fluoride acted like Mg2+ to inhibit mineralization while at higher concentration, it acted like crystal poisons (e.g., pyrophosphate phosphonates, citrate) to inhibit demineralization. However, unlike magnesium and pyrophosphate, fluoride at its higher concentrations was found to stimulate rather than inhibit the process of mineralization.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Kakkar M,Kapoor V,Singla SK,Jethi RKdoi
10.1007/s12011-020-02340-3subject
Has Abstractpub_date
2020-08-27 00:00:00eissn
0163-4984issn
1559-0720pii
10.1007/s12011-020-02340-3pub_type
杂志文章abstract::The movement of copper and zinc from the fertilized egg into the developing embryo and the subsequent association of the two metals with metallothionein-like proteins (MT) of chick liver was investigated. Hepatic levels of MT in 1-d-old chicks, estimated from specifically bound(115m)Cd, were increased eightfold over e...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02988942
更新日期:1983-12-01 00:00:00
abstract::Fatty acid composition of human immune cells influences their function. The aim of this study was to evaluate the effects of known toxicant and immunomodulator, cadmium, at low concentrations on levels of selected fatty acids (FAs) in THP-1 macrophages. The differentiation of THP-1 monocytes into macrophages was achie...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1071-6
更新日期:2018-03-01 00:00:00
abstract::Thirty rats were divided randomly into five groups and fed with different feeds. They were killed after 2 mo. Right thighs of these rats were taken as samples. Bone mineral densities of these samples were measured by the double-energy x-ray bone mineral densitometer, and trace elements contents of the samples were ana...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784252
更新日期:1999-01-01 00:00:00
abstract::A working analytical procedure for selenium determinations by INAA, using gamma spectrometry with a germanium well-type detector, is presented. The spectral line at 400.7 keV is employed, enhanced with the effect of energy summing in true coincidence of cascade photons. The main advantage of the method is high efficie...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917304
更新日期:1994-10-01 00:00:00
abstract::This study was undertaken to evaluate the impact of Plan Más Vida (PMV) on the micronutrient nutritional condition of children aged 1 to 6 years 1 year after PMV implementation. The food program was intended for low-income families from the province of Buenos Aires, Argentina and provided supplementary diets. A prospe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-8978-0
更新日期:2011-12-01 00:00:00
abstract::The aim of this study was to investigate the possible protective role of selenium and L-carnitine on oxidative stress induced by 2.45-GHz radiation in heart of rat. For this purpose, 30 male Wistar Albino rats were equally divided into five groups namely controls, sham controls, radiation-exposed rats, radiation-expos...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-8994-0
更新日期:2011-12-01 00:00:00
abstract::Trace elements can influence dental health, possibly by altering tooth resistance during preeruptive development. Therefore, it was investigated whether lead and fluoride would be incorporated into the calcifying matrices or the cellular parts of tooth germs in vitro. Using laser microprobe mass analysis, the localiza...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917184
更新日期:1989-01-01 00:00:00
abstract::China has eliminated iodine deficiency disorders since 2011 via the implementation of universal salt iodisation. Following this, a new revised salt iodisation policy was introduced to reduce iodine content in table salt. Since maternal iodine deficiency can lead to cognitive impairment and cretinism in infants, the ai...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02135-6
更新日期:2021-01-01 00:00:00
abstract::The aim of this study was to evaluate the effect of a daily intake of fluid and salt supplementation (FSS) on the deficiency of electrolytes, which is characterized by higher rather than lower plasma concentration of electrolytes during prolonged hypokinesia (HK) (decreased number of km taken per day). Forty long dist...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783342
更新日期:1998-07-01 00:00:00
abstract::The relationship between selenium (Se) deficiency-induced cardiac malfunction and endoplasmic reticulum (ER) stress is poorly understood. In the present study, 18 weaning Sprague Dawley rats were randomly fed with three different Se diets, and myocardial glutathione peroxidase (GPx) activity was measured by an enzyme ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9834-1
更新日期:2013-12-01 00:00:00
abstract::Aluminum (Al) exposure inhibits bone formation. Osteoblastic proliferation promotes bone formation. Therefore, we inferred that Al may inhibit bone formation by the inhibition of osteoblastic proliferation. However, the effects and molecular mechanisms of Al on osteoblastic proliferation are still under investigation....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0880-3
更新日期:2017-06-01 00:00:00
abstract::A dietary requirement is defined as the lowest continuing intake of a nutrient that for a specified indicator of adequacy, will maintain a defined level of nutriture in an individual. An essential dietary component is one that the body cannot synthesize in sufficient quantities to maintain health. Recommended dietary ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783138
更新日期:1998-01-01 00:00:00
abstract::The hypothesis was tested that marginal copper deficiency affects iron status. Copper restriction (1 vs 5 mg Cu/kg diet) significantly lowered iron concentrations and transferrin saturation in plasma and reduced blood hemoglobin, hematocrit, and iron concentrations in tibia and femur, but raised iron concentrations in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02786240
更新日期:1992-10-01 00:00:00
abstract::Chromium (Cr), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe) concentrations were quantified in serum (n = 112), milk (n = 112), liver (n = 70), and kidney samples (n = 67) of dairy cows from an iron-steel processing region (Payas-Iskenderun) and from an area free of industrial pollution (Antakya) in Hatay, loc...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:98:1:51
更新日期:2004-04-01 00:00:00
abstract::Patients with chronic kidney disease (CKD) have an increased incidence of cancer. It is well known that long periods of hemodialysis (HD) treatment are linked to DNA damage due to oxidative stress. In this study, we examined the effect of selenium (Se) supplementation to CKD patients on HD on the prevention of oxidati...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-010-8776-0
更新日期:2011-09-01 00:00:00
abstract::It has been demonstrated that zinc exerts its beneficial influence on skin fibroblasts. Propolis, a complex mixture of plant-derived and bees' products, was reported to stimulate cicatrization processes in skin and prevent infections. The aim of this study was to find out how zinc and propolis influence human skin fib...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0019-3
更新日期:2014-07-01 00:00:00
abstract::Control of elemental impurities (EIs) in pharmaceutical herbal products is currently important but not a very popular topic in modern toxicological analysis. The occurrence and concentration of EIs in the pharmaceutical herbal products should be controlled and meet the standards of directive International Conference o...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-1643-8
更新日期:2019-10-01 00:00:00
abstract::Since chromium(VI) is unreactive toward DNA under physiological conditions in vitro, the ability of carcinogenic chromium(VI) compounds to damage DNA depends on the presence of cellular redox components that reduce chromium(VI) to reactive species capable of interacting with DNA. We have examined the role of glutathio...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/BF02917282
更新日期:1989-07-01 00:00:00
abstract::Selenium (Se) is a trace element for human and animal health. Cadmium (Cd) is a known human carcinogen. The effects of Cd on the environment and humans are well known. Because chickens are at the top of the food chain, it is a good experimental animal model for assessing heavy metal toxicity and its potential threat t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01858-5
更新日期:2020-06-01 00:00:00
abstract::In vitro distribution of aluminium between plasma and erythrocytes has been studied in the presence of variable amounts of sodium L-glutamate. With a red blood cell suspension in isotonic sodium chloride, aluminium remains confined in erythrocytes even when the sodium L-glutamate concentration increases in the medium....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990262
更新日期:1990-04-01 00:00:00
abstract::The study was undertaken to investigate the influence of alpha-tocopherol on zinc, copper, iron, calcium, magnesium, and potassium concentrations in serum of rats with bleomycin-induced pulmonary fibrosis. Fourteen Wistar albino rats were randomly divided into two groups of seven animals each. The first group was trea...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:114:1:175
更新日期:2006-01-01 00:00:00
abstract::In this experimental study, the effect of cadmium on cold and restraint stress-induced gastric lesions has been studied. Rats received 15 micrograms/mL cadmium-containing water for 30 d, and at the end of this period, they were subjected to cold and restraint stress. Cadmium accumulation in gastric mucosa was associat...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790120
更新日期:1995-01-01 00:00:00
abstract::The role of zinc (Zn) in hepatic steatosis of patients with HCV-related chronic liver disease (CLD-C) remains uncertain, although persistent HCV infection often evokes hepatic steatosis. The primary purpose of this study was to elucidate the contribution of Zn deficiency to hepatic steatosis in patients with CLD-C. Fi...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-014-0177-3
更新日期:2015-02-01 00:00:00
abstract::The serum copper and zinc levels were determined by atomic absorption spectrometry in 135 Hodgkin's disease (HD) patients and in 100 healthy controls. These values were used to explore the application value of the serum copper/zinc ratio in the histologic classification and prognosis in this illness. The resuls show t...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/bter:83:2:133
更新日期:2001-11-01 00:00:00
abstract::Vanadium compounds maintain euglycemic effects in diabetic rats long after drug withdrawal and bis(α-furancarboxylato)oxovanadium(IV) (BFOV) possesses potent antidiabetic effects in diabetic rats. Here, we investigated the treatment and posttreatment effects of BFOV in diabetic Kuo Kondo [1, 2] with Ay gene (KKAy) mic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9689-5
更新日期:2013-06-01 00:00:00
abstract::The objective of this study was to investigate correlations between oxidative stress, metabolism of mineral elements, and lameness in dairy cows. Forty multiparous Chinese Holstein dairy cows were selected and divided into two groups (healthy vs lame, n = 20) by gait score. The experiment lasted for 60 days and sample...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0207-1
更新日期:2015-03-01 00:00:00
abstract::Nowadays, 70 % of global monogastric feeds contains an exogenous phytase. Phytase supplementation has enabled a more efficient utilisation of phytate phosphorous (P) and reduction of P pollution. Trace minerals, such as iron (Fe), zinc (Zn), copper (Cu) and manganese (Mn) are essential for maintaining health and immun...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0161-y
更新日期:2015-02-01 00:00:00
abstract::This study aimed to determine the relationship between the metabolic and endocrinological pathologies in polycystic ovary syndrome (PCOS) and the levels of arsenic, chromium, cadmium, lead, mercury, antimony, zinc, and copper to evaluate the relationship of these toxic metals with inflammatory/oxidative parameters. Th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02220-w
更新日期:2020-11-01 00:00:00
abstract::The aim of this study was to assess the effect of sibutramine on mineral status and selected biochemical parameters in obese women. The study was conducted on 24 patients who received 15 mg daily doses of sibutramine for 12 weeks, and on 20 patients who received placebo. At the baseline, after the sixth and twelfth we...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9425-6
更新日期:2012-11-01 00:00:00
abstract::The biological function of selenium (Se) is mainly elicited through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, is essential for the normal function of the skeletal muscle system. To investigate the possible relationship of Se in the process of differentiation in chicken myo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9520-8
更新日期:2012-12-01 00:00:00