Abstract:
:The serum copper and zinc levels were determined by atomic absorption spectrometry in 135 Hodgkin's disease (HD) patients and in 100 healthy controls. These values were used to explore the application value of the serum copper/zinc ratio in the histologic classification and prognosis in this illness. The resuls show that serum copper and the copper/zinc ratio were higher and the serum zinc level was lower in the HD patients when compared to the healthy individuals (p < 0.01, 0.001, and 0.01, respectively). The serum copper and copper/zinc ratio were significantly higher in the lymphocyte-depleted type of HD than in the patients with the mixed-cellular type of HD. These values were also higher and the serum zinc was lower in the patients with mixed-cellular HD when compared to the nodular-sclerosis and the lymphocyte-predominant types of the disease (p < 0.01 and 0.001, respectively). It was also shown that as the disease progresses, the serum copper level and copper/zinc ratio rises with the concomitant decrease of the corresponding serum zinc level. These trends are reversed in cases where the disease is in remission. Both the serum copper level and the copper/zinc ratio were strongly correlated to histopathological changes, clinical stage, and prognosis of Hodgkin's disease.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Cunzhi H,Jiexian J,Xianwen Z,Jingang G,Suling Hdoi
10.1385/bter:83:2:133subject
Has Abstractpub_date
2001-11-01 00:00:00pages
133-8issue
2eissn
0163-4984issn
1559-0720pii
BTER:83:2:133journal_volume
83pub_type
临床试验,杂志文章abstract::Urine lead level is one of the most employed measures of lead exposure and risk. The urine samples used in this study were obtained from ten healthy male cyclists. Dispersive liquid-liquid microextraction combined with ultraviolet and visible spectrophotometry was utilized for preconcentration, extraction, and determi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0844-7
更新日期:2017-04-01 00:00:00
abstract::Concentrations of selected metals (Cu, Mn, Zn, Cd) in tea leaves were investigated. Samples included black, green, and other (red, white, yellow, and oolong) teas. They were purchased on a local market but they covered different countries of origin. Beverages like yerba mate, rooibos, and fruit teas were also included...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1140-x
更新日期:2018-06-01 00:00:00
abstract::The aim of this study was to evaluate the effect of a daily intake of fluid and salt supplementation (FSS) on the deficiency of electrolytes, which is characterized by higher rather than lower plasma concentration of electrolytes during prolonged hypokinesia (HK) (decreased number of km taken per day). Forty long dist...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783342
更新日期:1998-07-01 00:00:00
abstract::The purpose of this research was to investigate whether copper (Cu) exposure could induce apoptosis via endoplasmic reticulum stress (ERS) in skeletal muscle of broilers. A total of 240 one-day-old chickens were randomly divided into four groups by free access; the diets are as follows: control diet (Cu 11 mg/kg, cont...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02076-0
更新日期:2020-12-01 00:00:00
abstract::Sediments from 14 stations in the Foshan Waterway, a river crossing the industrial district of Guangdong Province, South China, were sampled and subsequently analyzed. The 14 stations were selected for the pollution discharging features of the river, such as the hydrology, the distribution of pollution sources, and th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9789-2
更新日期:2013-11-01 00:00:00
abstract::The relationship between Ni-induced hepatic lipid peroxidation (LPO) and the concentrations of Ni and trace elements was investigated in male ICR mice. The protective effects of antioxidants were also examined. Hepatic LPO and the concentrations of Ni, Fe, Cu, and Zn in the liver were enhanced after an ip injection of...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784030
更新日期:1998-02-01 00:00:00
abstract::The risk of premature ovarian failure (POF) increases in association with alteration in immunological parameters and oxidative stress (OS). Adequate intake of trace elements is required for antioxidant property and immune defense mechanism. The aim of this study was to explore the involvement of trace elements, OS, an...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1197-6
更新日期:2018-08-01 00:00:00
abstract::Present study investigates relationships between total and bioaccessibility of trace elements (Cd, Co, Cr, Cu, Mn, NI, Pb, V, and Zn) concentrations in sediment and their bioaccumulation in species in Shadegan wetland in southwest of Iran. Bioavailability factor (BAF) and translocation factor (TF) were calculated in p...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8795-x
更新日期:2011-09-01 00:00:00
abstract::To elucidate compositional changes of the cardiac walls with development and aging, the authors investigated changes of elements in the atrial and ventricular walls of monkeys. The left and right atrial walls, left and right ventricular walls, and interatrial and interventricular septa were resected from the subjects....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:110:3:233
更新日期:2006-06-01 00:00:00
abstract::Since 1992, the International Atomic Energy Agency (IAEA) has been promoting studies of air pollution using a standard design of air sampler that provides separation on filters into two size fractions with cutoffs of 2.5 and 10 microns (approximately). These are the size ranges presently considered to have the most im...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784202
更新日期:1999-01-01 00:00:00
abstract::The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0477-2
更新日期:2016-04-01 00:00:00
abstract::Characterization of coffee terroirs is important to determine authenticity and provide confidence for consumers to select the right product. In this regard, Amhara Region, which is located at the northwestern part of Ethiopia, produces various local coffee types with distinct cup qualities. The coffees are, however, n...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01866-5
更新日期:2020-06-01 00:00:00
abstract::A series of experiments was conducted to study the effects of dietary and injected lead (as Pb acetate-3H2O) and of dietary Cd, Hg, and Se on fatty acid composition of serum lipids of chicks as measured by gas-liquid chromatography. The effect of dietary Pb on fatty acid composition of erythrocyte membranes was measur...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02989250
更新日期:1985-06-01 00:00:00
abstract::AFB1 is a mycotoxin which exerts their cytotoxicity through increasing oxidative damage in target organ. Kidney is one of target organs vulnerable to damage caused by AFB1. In this study, Madin-Darby canine kidney (MDCK) cells were used to evaluate the AFB1-induced cell damage by the MTT assay. The results revealed th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9887-9
更新日期:2014-03-01 00:00:00
abstract::Intact and non-intact urinary stones richening with calcium oxalate were collected and characterized. The elemental analysis, phase quantifications, and function groups were determined by different spectroscopic techniques, namely: energy-dispersive X-ray fluorescence (EDXRF), the synchrotron radiation X-ray diffracti...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02424-0
更新日期:2020-10-10 00:00:00
abstract::Both thermal and epithermal neutron activation analyses have been employed to determine chromium and nickel in lung tissue and arsenic in urine. Based on accuracy, precision, and detection limits, these techniques have been successfully used to analyze lung tissue from a deceased welder, who died, from cancer, and to ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02796646
更新日期:1987-08-01 00:00:00
abstract::Significant disorders of liver metabolic pathways enzymes after high-cholesterol diet could give information on liver steatosis development. This process could probably also be inhibited by some compounds, as examined in rabbits. Forty-two male rabbits were served a high-cholesterol diet (2 g%) (0.67 g/kg b.m./24 h) w...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-0070-4
更新日期:2007-01-01 00:00:00
abstract::Being a proven photocatalyst, nano-anatase is capable of undergoing electron transfer reactions under light. In previous studies, we had proven that nano-anatase improved photosynthesis and greatly promoted spinach growth. However, the molecular mechanisms of carbon reaction promoted by nano-anatase are still not clea...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8203-y
更新日期:2008-01-01 00:00:00
abstract::Lipid disturbance induced by high-fat diet is a worldwide problem, and it can induce inflammation and oxidative stress in vivo. Zinc is considered as an antioxidant, anti-inflammatory agent. Since matrix metalloprotease 2 (MMP2) and matrix metalloprotease 9 (MMP9)'s expressions are changed under many pathological cond...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0367-7
更新日期:2015-12-01 00:00:00
abstract::In this study, the induction of metallothionein (MT) in one species of oyster Ostrea edulis exposed to copper (Cu) and zinc (Zn) was examined. The quantity of total protein (mg protein/mg dry wt) in each sample and the measurement of MT were determined by the Lowry and silver (Ag)-saturation methods. Our results show ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784547
更新日期:1996-07-01 00:00:00
abstract::Cadmium concentrations were determined in the hair of 226 school children in an industrial and in a rural area of Tarragona Province (NE Spain). The influence of sex, age, hair color, smoking habits of the household members, and parents' occupation on the children's hair cadmium levels was also evaluated. Children liv...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02863080
更新日期:1991-02-01 00:00:00
abstract::The biological function of selenium (Se) is mainly elicited through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, is essential for the normal function of the skeletal muscle system. To investigate the possible relationship of Se in the process of differentiation in chicken myo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9520-8
更新日期:2012-12-01 00:00:00
abstract::An increase in hepatic iron concentration might exacerbate liver injury. However, it is unknown whether hepatic iron overload may exacerbate acute liver injury from various toxins. Therefore, we evaluated how manipulations to increase hepatic iron concentration affected the extent of acute liver injury from thioacetam...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0110-9
更新日期:2015-02-01 00:00:00
abstract::Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is the most common human enzymopathy in the world. Trace elements are important for normal hematopoiesis and can play a role in acute hemolytic anemia induced by G-6-PD deficiency. For this purpose, we studied two groups consisting of 10 male children who are G-6-P...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:99:1-3:041
更新日期:2004-07-01 00:00:00
abstract::The aim of this study was to evaluate and compare the oxidative profiles of three thyroid disorders: Graves' disease (GD), Hashimoto thyroiditis (HT), and papillary thyroid cancer (PTC). Malondialdehyde levels (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) activities were examined ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8625-1
更新日期:2010-12-01 00:00:00
abstract::The effects of zinc on growing rats were characterized using the dietary zinc-deficient (ZD) and Zinc-overdose (ZO) models. Zinc deficiency had negative effects on the host final body weight and liver zinc content, whereas zinc overdose had positive effects. In order to identify the molecular changes in the liver resp...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02686028
更新日期:2007-02-01 00:00:00
abstract::The concentrations of elements in urine obtained from cats with urolithiasis were compared with those of healthy cats. The concentration of several elements, such as sodium (Na), phosphorus (P), sulfur (S), and potassium (K), in urine obtained from cats with urolithiasis was significantly higher than that of healthy c...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8893-9
更新日期:2011-11-01 00:00:00
abstract::Zinc uptake regulator (Zur) is a negative transcriptional regulator of bacteria that belongs to the FUR superfamily of proteins and regulates zinc (Zn) homeostasis under extreme Zn conditions. The Zur protein of Bacillus anthracis (BaZur) was though characterized previously, but the residues of this transcriptional re...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02427-x
更新日期:2020-10-14 00:00:00
abstract::Activity of the immunoregulatory peptide thymulin reflects differences in zinc status. This study compared thymulin activity with four other zinc status measures in rats fed zinc at either 5 or 25 ppm. Rats fed the lower zinc showed the following results compared with rats with adequate zinc intake: serum thymulin act...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02159-y
更新日期:2021-02-01 00:00:00
abstract::Platelet-rich fibrin (PRF) is widely used blood-derived biomaterial which is directly applied to the surgical wounds. Depending on its autologous origin, PRF is thought as a safe material. However, it is not known to what extent the blood-derived toxins can be found in the PRF by considering the systemic exposure rate...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01695-6
更新日期:2019-10-01 00:00:00