The movement of zinc and copper from the fertilized egg into metallothionein-like proteins in developing chick hepatic tissue.

Abstract:

:The movement of copper and zinc from the fertilized egg into the developing embryo and the subsequent association of the two metals with metallothionein-like proteins (MT) of chick liver was investigated. Hepatic levels of MT in 1-d-old chicks, estimated from specifically bound(115m)Cd, were increased eightfold over endogenous levels of these copper- and zinc-binding proteins in adult liver. Copper was assimilated from the oocyte into the embryo more rapidly than zinc in the early stages of embryogenesis. Between 15 and 16 d of development, during the time that (MT) was detected, there was a significant increase in copper concentration, whereas hepatic zinc concentration remained relatively constant.

journal_name

Biol Trace Elem Res

authors

Sandrock BC,Kern SR,Bryan SE

doi

10.1007/BF02988942

subject

Has Abstract

pub_date

1983-12-01 00:00:00

pages

503-15

issue

6

eissn

0163-4984

issn

1559-0720

journal_volume

5

pub_type

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