Abstract:
:The distribution and chemical species of iodine in various subcellular fractions of human liver were studied by using epithermal neutron activation analysis combined with chemical and biochemical separation techniques, such as gradient centrifugation and gel chromatography. It was found that the total iodine content orders in various subcellular fractions is as follows: nuclei > cytosol > mitochondria > lysosome > microsome. In the lysosomal fraction, iodine is mainly bound to macromolecules, whereas in the nuclei and mitochondrial fractions, mainly with lower-molecular-weight organic compounds. In the cytosol fraction, iodine is combined with three proteins, in which iodine is chiefly bound with mid- and high-molecular-weight proteins.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Hou X,Chen C,Ding W,Chai Cdoi
10.1007/BF02783916subject
Has Abstractpub_date
1999-07-01 00:00:00pages
69-76issue
1eissn
0163-4984issn
1559-0720journal_volume
69pub_type
杂志文章abstract::Zinc (mostly as free/labile Zn2+) is an essential structural constituent of many proteins, including enzymes in cellular signaling pathways via functioning as an important signaling molecule in mammalian cells. In cardiomyocytes at resting condition, intracellular labile Zn2+ concentration ([Zn2+]i) is in the nanomola...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/s12011-018-1464-1
更新日期:2019-03-01 00:00:00
abstract::In 47 children with malignancy, zinc status, growth, and performance during standard treatment were compared with those in controls. At diagnosis, growth was retarded and hair zinc values were high, 2.4 +/- 0.7 mumol/g, as in chronic deficiency. During induction therapy, serum declined to 10.4 +/- 2.3 mumol/L and urin...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02991414
更新日期:1991-09-01 00:00:00
abstract::Oxidative stress is a main factor in the pathogenesis of severe acute pancreatitis (SAP). The ability of zinc (Zn) to retard oxidative processes has been recognized for many years. This study aims to examine the levels of free oxygen radicals and antioxidant enzyme in SAP rats and know the effect of Zn supplementation...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9971-1
更新日期:2014-06-01 00:00:00
abstract::A study was conducted to validate the effects of nano form of zinc (NZn) on nutrient digestibility, zinc retention, organ and serum zinc profile, and hepatic metallothionein gene expression in Wistar albino rats (WAR). Nano zinc (NZn) was synthesized through chemical method, by using 0.45 M zinc nitrate [Zn(NO3)2.6H2O...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1517-5
更新日期:2019-07-01 00:00:00
abstract::Mannheimia haemolytica is the main bacterial pathogen isolated in bovine respiratory disease (BRD), a common disease affecting calves before weaning. Previous research has shown that experimental infection with bovine herpesvirus 1, a respiratory virus, decreases plasma zinc (Zn) levels. However, changes in plasma Zn ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02145-4
更新日期:2021-01-01 00:00:00
abstract::Control of elemental impurities (EIs) in pharmaceutical herbal products is currently important but not a very popular topic in modern toxicological analysis. The occurrence and concentration of EIs in the pharmaceutical herbal products should be controlled and meet the standards of directive International Conference o...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-1643-8
更新日期:2019-10-01 00:00:00
abstract::The key role of osteoblasts in skeletal fluorosis makes the exploration of the possible mechanisms of the fluoride-induced oxidative stress of osteoblasts of great importance. In this article, the in vitro effects of fluoride on the oxidative stress of osteoblasts are presented. To study the inhibitory effect of baica...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02685921
更新日期:2007-04-01 00:00:00
abstract::Cactus (Opuntia ficus-indica) is a xerophyte plant that belongs to the Cactaceae family. The present study was designed to investigate the possible protective effects of cactus cladodes extract (CCE) on sodium dichromate-induced testis damage in adult male Wistar rats. For this purpose, CCE at a dose of 100 mg/kg was ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9969-8
更新日期:2014-06-01 00:00:00
abstract::Addition of zinc lowers the toxicity level of cadmium in cultured CHO cells. Cell survival and protein synthesis were used to measure the cellular toxicity of cadmium.(109)Cd was used to measure cadmium uptake by the cells. The results suggest that these class IIB transition metals, zinc and cadmium, share a common tr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785356
更新日期:1980-09-01 00:00:00
abstract::Analysis of variance, analysis of covariance, correlation coefficient, multiple correlation, and partial correlation coefficient statistical tests were applied to Cs, Cr, Co, Fe, Rb, Sc, Se, and Zn content in human ovaries in order to evaluate statistically the possible relationships between these trace elements at: t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784090
更新日期:1996-04-01 00:00:00
abstract::It has been shown recently that Selenium (Se), an essential trace element for humans, is involved in the regulation of thyroid function, since the enzyme that catalyzes the liver conversion of the thyroid hormone T4 to the more active form T3 is a selenoenzyme. In chronic uremic patients, low blood Se levels as well a...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02785281
更新日期:1996-12-01 00:00:00
abstract::Strontium stimulates cartilage matrix formation in vitro. However, the mechanisms governing these effects have not yet been extensively reported. In this study, chondrocytes were isolated from rat articular cartilage by enzymatic digestion and cultured for 24-72 h with 1-5 mM strontium. We investigated the effects of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9640-9
更新日期:2013-06-01 00:00:00
abstract::A rapid cyclic instrumental neutron activation analysis (CINAA) method has been used to determine the selenium content of 27 duplicate diet samples from each of the 27 districts surrounding Pinhel, Portugal. The accuracy and precision of the CINAA method have been evaluated by analyzing certified reference materials a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992719
更新日期:1990-07-01 00:00:00
abstract::Because nickel may have a biological function in a pathway in which vitamin B12 is important, an experiment was performed to determine the effects of nitrous oxide exposure in rats deprived of nickel. Exposure to nitrous oxide (N2O) causes inactivation of cobalamin and a subsequent decrease in the vitamin B12-dependen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783980
更新日期:1993-07-01 00:00:00
abstract::Selenium is known to be a neuroprotective agent in respect to a number of neuronal diseases and pain. The aim of this study was to evaluate the neuroprotective effect of the oral administration of selenium nanoparticles in rats with spinal cord injury (SCI). Forty adult female rats were randomly assigned to two equal ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1371-5
更新日期:2019-01-01 00:00:00
abstract::The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0477-2
更新日期:2016-04-01 00:00:00
abstract::The toxicological literature is replete with studies attempting to explain the mechanism of action of organophosphorus (OP) insecticides to their anticholinesterase activities, but not much is known about the metabolism and detoxification of these compounds. The goal of this study was to ascertain the toxic effects of...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:74:2:171
更新日期:2000-05-01 00:00:00
abstract::The current study aims to assess the concentration of cadmium (Cd) and lead (Pb) in five tissues of Cirrhinus mrigala, Labeo rohita, and Catla catla collected from fishponds of Jamshoro and Larkana, Sindh, Pakistan. Meanwhile, the levels of Cd and Pb in feeding materials, water, and sediments of fishponds of both area...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1628-z
更新日期:2019-10-01 00:00:00
abstract::Adverse effects of mercury on female reproduction are reported; however, its effect on myogenic activity of uterus and mechanism thereof is obscure. Present study was undertaken to unravel the mechanistic pathways of mercuric chloride (HgCl2)-induced myometrial contraction in rats. Isometric tension in myometrial stri...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1379-x
更新日期:2019-02-01 00:00:00
abstract::The influence of injection periods of 3-(1H-pyrrol-2-yl)-1H-indazole regarding vitamins A, E, C, selenium (Se), malondialdehyde (MDA) levels, and glutathione peroxidase (GSH-Px) activity in rats has been investigated. The substance was given by subcutaneous injection at 20 mg/kg every other day for a total of 15 injec...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8517-4
更新日期:2010-07-01 00:00:00
abstract::Evidence linking copper and zinc to hypertension are limited and conflicting. Data from the National Health and Nutrition Examination Survey (NHANES) 2007-2014 were used. Zinc and copper intake from diet and supplements was assessed with 24-h dietary recall. Hypertension was defined as systolic blood pressure (SBP) ≥ ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1320-3
更新日期:2018-12-01 00:00:00
abstract::Women with preeclampsia have been shown to have elevated blood levels of the metabolite homocysteine, and alterations in blood levels of zinc and copper have also been reported. This study measured plasma levels of zinc, copper, and homocysteine in women with preeclampsia and in women with healthy, normotensive pregna...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:104:2:097
更新日期:2005-05-01 00:00:00
abstract::Guizhou black goats are essential to the production system in the Wumeng prairie in the Western China. This study aimed to determine the influence of nano-copper on antioxidant system in copper-deprived Guizhou black goats. We analyzed mineral contents in soil, forage, and goats' tissues. Blood parameters were also de...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02342-1
更新日期:2020-08-18 00:00:00
abstract::Multielemental detection using Instrumental Neutron Activation Analysis (INAA) and Proton-Induced X-Ray Emission (PIXE) of drinkable water of Florence (Italy) is described. The concentrations of 52 elements were measured. No chemical treatment was performed on the samples, before or after irradiation. On the basis of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992691
更新日期:1990-07-01 00:00:00
abstract::Various studies indicate the role of manganese (Mn) in the virulence of pathogens. Salmonella is an intracellular pathogen which is able to multiply within the macrophages. The present study was therefore, designed to assess the effect of Mn supplementation on Salmonella-macrophage interactions particularly in referen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8406-x
更新日期:2010-01-01 00:00:00
abstract::AFB1 is a mycotoxin which exerts their cytotoxicity through increasing oxidative damage in target organ. Kidney is one of target organs vulnerable to damage caused by AFB1. In this study, Madin-Darby canine kidney (MDCK) cells were used to evaluate the AFB1-induced cell damage by the MTT assay. The results revealed th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9887-9
更新日期:2014-03-01 00:00:00
abstract::Arsenite has been known for half a century to have a protective effect against selenium poisoning. Paradoxically, arsenite inhibits the conversion of inorganic selenium salts to methylated excretory products, although methylation has long been regarded as a detoxification mechanism for selenium. Moreover, there is evi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02919103
更新日期:1989-04-01 00:00:00
abstract::We investigated the rooting rate, the number of roots, and the state of growth of loquat (Eriobotrya japonica Lindi) plantlet in medium where La(NO3)3 (0.5-100.0 micromol/L) was added 20 d after transplanting. The activity of peroxidase, nitrate reductase, and the fresh weight of roots were determined 44 d after trans...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:89:3:277
更新日期:2002-12-01 00:00:00
abstract::The objective of this study was to determine whether different dietary vitamin E (VE) and selenium (Se) levels affect the nutrient digestibility, production performance, and antioxidant abilities of growing furring blue foxes. A 4 × 2 factorial arrangement that included 4 levels of VE (0, 100, 200, or 400 mg/kg diet f...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-1655-4
更新日期:2019-12-01 00:00:00
abstract::Samples of Evernia prunastri, collected in a mountainous zone, were exposed in urban and highly industrialized areas in order to monitor the atmospheric pollution. Amounts of Cr, Mn, Fe, Ni, Cu, Zn, and Pb were determined by EDXRF spectrometry in secondary target excitation mode and in the thin film approach. An incre...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917318
更新日期:1994-10-01 00:00:00