Abstract：
:The effect of ad libitum ingestion of selenium (Se) in drinking water (0.15 mg SeO2/L) for 3 wk on the brain weight, total brain protein, glutathione (GSH) level, catalase activity, and lipid peroxidation in the brain of protein-undernourished (PU) rats was investigated, in an attempt to determine whether antioxidants alone can reverse some of the neuropathological changes associated with protein undernutrition in rats. Feeding on a normal diet (16% casein) by well-fed rats or a low-protein diet (5% casein) by PU rats and Se-treated PU rats lasted 14 wk. Se-treated PU rats were given Se in drinking water during the last 3 wk of the experiment. Results show that protein undernutrition induced significant reductions (p < 0.001) in brain weight, total brain protein, and catalase activity (p < 0.05) while it induced a significant increase (p < 0.05) in lipid peroxidation when compared with well-nourished rats; but no significant effect was observed for the GSH level. However, the ingestion of Se in drinking water by PU rats for 3 wk resulted in significant increases (p < 0.05) in brain weight, catalase activity, and total brain protein but induced a significant reduction (p < 0.05) in lipid peroxidation when compared with PU rats given water. The values obtained for Se-treated PU rats are comparable with those obtained for well-nourished rats. The GSH level was, however, not affected by Se ingestion. We suggest that Se, by inducing increases in the concentration of certain proteins, including catalase, in the brain, abolished some of the pathological changes associated with protein undernutrition in the brain, and appears as a promising antioxidant in the prevention and management of pro-oxidant-induced brain damage.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Adebayo OL,Adenuga GAdoi
10.1007/BF02685933subject
Has Abstractpub_date
2007-05-01 00:00:00pages
227-34issue
2eissn
0163-4984issn
1559-0720pii
BTER:116:2:227journal_volume
116pub_type
杂志文章abstract：:The k0 standardization method was adapted for NAA with stable low-flux reactors where flux monitors are not needed. The modified k0 method offers the convenience of the use of libraries of sensitivity constants. It was compared to the relative method for 52 elements using a SLOWPOKE reactor and 6 counting geometries. ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784232
更新日期：1999-01-01 00:00:00
abstract：:Multielemental detection using Instrumental Neutron Activation Analysis (INAA) and Proton-Induced X-Ray Emission (PIXE) of drinkable water of Florence (Italy) is described. The concentrations of 52 elements were measured. No chemical treatment was performed on the samples, before or after irradiation. On the basis of ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02992691
更新日期：1990-07-01 00:00:00
abstract：:The aim of this study was to evaluate the impact of three different chromium forms--chromic chloride (CrCl3), chromium picolinate (CrPic), and a newly synthesized complex of chromium chelated with small peptides (CrSP)--on protein metabolism in vitro. In cultured skeletal muscle cells, CrSP was able to increase the ba...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8579-3
更新日期：2010-11-01 00:00:00
abstract：:In the present study, aluminum (Al) accumulation has been examined after aluminum loading in mice. The kidney, liver, and brain aluminum levels for mice that had been treated orally with aluminum hydroxide for 105 d and for the control group were determined using graphite furnace atomic absorption spectrophotometry (G...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917223
更新日期：1994-04-01 00:00:00
abstract：:In this study, experimental hyperthyroidism was established and used to investigate possible alterations in the calcium (Ca), magnesium (Mg), and zinc (Zn) homeostasis by assessing their concentrations in plasma and erythrocytes. In the L-thyroxine-induced hyperthyroidism condition, the experimental animals show a sig...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02778196
更新日期：1997-05-01 00:00:00
abstract：:To elucidate compositional changes of the mitral valve with aging, the authors investigated the relationships among element contents in the mitral valves. The subjects consisted of 10 men and 15 women, ranging in age from 65 to 102 yr. After the ordinary dissection, mitral valves, lower parts of the interventricular s...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:88:3:203
更新日期：2002-09-01 00:00:00
abstract：:The present study was undertaken to investigate the utility of cystatin C (CysC) as an early biomarker of cadmium (Cd)-induced renal injury. The study was carried out on 50 adult male individuals divided into five groups of 10 individuals as follows: control, welders, smoker welders, diabetic welders, and smoker diabe...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-9939-1
更新日期：2014-06-01 00:00:00
abstract：:Information on cadmium (Cd) uptake and transport is essential to understand better the physiology of Cd tolerance in plants. In this study, Cd uptake, translocation, and tolerance were investigated in AHA1 (Arabidopsis plasma membrane H(+)-ATPase gene) overexpressed plants. Exposed to 10 µM CdCl(2), AHA1OX showed a hi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8657-6
更新日期：2011-02-01 00:00:00
abstract：:A survey of mercury (Hg) and selenium (Se) contents was performed in fish collected from lakes located in two National Parks of the northern patagonian Andean range. Two native species, catfish (Diplomystes viedmensis) and creole perch (Percichthys trucha), and three introduced species, brown trout (Salmo trutta), rai...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-8059-6
更新日期：2008-04-01 00:00:00
abstract：:The present study was conducted to assess the influence of dietary zinc nanoparticles (size 50 nm) on the growth, biochemical constituents, enzymatic antioxidant levels and the nonspecific immune response of the freshwater prawn, Macrobrachium rosenbergii post larvae (PL). The concentrations of dietary supplement zinc...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0026-4
更新日期：2014-07-01 00:00:00
abstract：:The seeds of Nelumbo nucifera (Lotus) have been used in the traditional system of medicine for various ailments including diabetes. The present study was aimed at analyzing the levels of biologically important trace elements in the lotus seeds by atomic absorption spectroscopy and evaluating the hypoglycemic propertie...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8614-4
更新日期：2010-12-01 00:00:00
abstract：:In the present study, spectroscopic determinations of copper ions using chimeric metal-binding green fluorescent protein (His6GFP) as an active indicator have been explored. Supplementation of copper ions to the GFP solution led to a remarkable decrease of fluorescent intensity corresponding to metal concentrations. F...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8476-9
更新日期：2010-06-01 00:00:00
abstract：:We have previously shown that a low-copper (Cu) diet produced alterations in placental Cu transport and fetal Cu stores. Because Cu deficiency has been associated with lipid deposition in rat dam liver, we hypothesized that a high fat intake, a prevalent dietary habit in many populations, may worsen fetal Cu status an...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784069
更新日期：1999-02-01 00:00:00
abstract：:The effect of zinc deficiency on calmodulin function was investigated by assessing the in vivo activity of two calmodulin regulated enzymes, adenosine 3',5'-monophosphate (c-AMP) and guanosine 3',5'-monophosphate (c-GMP) phosphodiesterase (PDE) in several rat tissues. Enzymatic activities in brain, heart, and testis o...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02797137
更新日期：1988-08-01 00:00:00
abstract：:Concentration of heavy metals (lead (Pb), cadmium (Cd), chromium (Cr), and copper (Cu)) was determined in the liver, gills, kidneys, and muscles of eight edible fish species (Channa punctata, Cirrhinus reba, Labeo rohita, Heteropneustes fossilis, Mystus cavasius, Oreochromis niloticus, Puntius sophore, and Wallago att...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-011-9011-3
更新日期：2011-12-01 00:00:00
abstract：:The present investigation was carried out to determine the molybdenum (Mo) status of blood plasma and milk of lactating cows at the Livestock Experimental Station, Khizer abad, Sargodha, Pakistan. Blood and milk from the lactating cows were sampled periodically after every month during winter so as to examine the effe...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8874-z
更新日期：2011-10-01 00:00:00
abstract：:The effects of dietary sodium selenite and vitamin E on the microvascular permeability of rat organs such as heart, brain, kidney, liver and eye were investigated by using the Evans blue leakage method. Combined deficiency of selenium and vitamin E caused an increase in the permeability of the heart and eye with respe...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783332
更新日期：1998-07-01 00:00:00
abstract：:To elucidate compositional changes of the pubic symphysis (PS) by aging, elements of pubic symphysis (PSs) removed from 26 cadavers were determined by inductively coupled plasma atomic-emission spectrometry. It was found that the relative contents (RCs) of calcium and phosphorus in women's PSs were about three- and fi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783243
更新日期：1997-01-01 00:00:00
abstract：:Copper oxide nanoparticles (CuONPs) are widely used in several products and their release into the environment can cause toxicity to major food crops. In this study, toxic responses as a result of CuONPs exposure were studied in soybean (Glycine max L.) seedlings. The plants were grown in 1/2 strength Murashige and Sk...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0106-5
更新日期：2014-12-01 00:00:00
abstract：:In 47 children with malignancy, zinc status, growth, and performance during standard treatment were compared with those in controls. At diagnosis, growth was retarded and hair zinc values were high, 2.4 +/- 0.7 mumol/g, as in chronic deficiency. During induction therapy, serum declined to 10.4 +/- 2.3 mumol/L and urin...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02991414
更新日期：1991-09-01 00:00:00
abstract：:Being a proven photocatalyst, nano-anatase is capable of undergoing electron transfer reactions under light. In previous studies, we had proven that nano-anatase improved photosynthesis and greatly promoted spinach growth. However, the molecular mechanisms of carbon reaction promoted by nano-anatase are still not clea...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8203-y
更新日期：2008-01-01 00:00:00
abstract：:X-ray fluorescence experiments at the Photon Factory in Japan are described. An energy-dispersive X-ray fluorescence system was combined with various excitation modes, i.e., a continuum and a monochromatic excitation, which consist of a crystal monochromator or a wide band pass monochromator. These excitation modes pr...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02796677
更新日期：1987-04-01 00:00:00
abstract：:The aim of this study was to investigate the influence of Se deficiency on the transcription of inflammatory factors and selenoprotein genes in the kidneys of broiler chicks. One hundred fifty 1-day-old broiler chicks were randomly assigned to two groups fed with either a low-Se diet (L group, 0.033 mg/kg Se) or an ad...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0512-3
更新日期：2016-05-01 00:00:00
abstract：:Conflicting results exist between selenium concentration and preeclampsia. The role of selenium in the development of preeclampsia is unclear. We conducted a meta-analysis to compare the blood selenium level in patients with preeclampsia and healthy pregnant women, and to determine the effectiveness of selenium supple...
journal_title：Biological trace element research
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s12011-015-0545-7
更新日期：2016-06-01 00:00:00
abstract：:The objective of the study was analysis of hair trace elements content in children with goiter living in Aktubinsk region. Children with goiter and age- and sex-adjusted controls were involved in the current study. Hair trace elements content was assessed using inductively coupled plasma mass spectrometry. Thyroid vol...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/s12011-016-0711-6
更新日期：2016-12-01 00:00:00
abstract：:Deficiencies in Cu, Se, and Zn impair one or more biochemical functions, and excess are associated with toxicity. Baseline studies on the Ghanaian population are scanty. The study was undertaken to determine whether significant rural/urban differences in the serum levels of Cu, Se, and Zn did exist. Forty males/60 fem...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8571-y
更新日期：2010-11-01 00:00:00
abstract：:The effect of manganese (Mn) supplementation on bone mineral density (BMD) and bone metabolism parameters was determined in ovariectomized Sprague-Dawley rats. Rats were divided into four groups (OVX, OVX+Mn, sham, sham+Mn) and fed with different intake levels of manganese (adequate 0.001% Mn, supplementation 0.01% Mn...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8119-6
更新日期：2008-07-01 00:00:00
abstract：:The protective effects of caffeic acid on angiotensin-converting enzyme (ACE) and purinergic enzyme activities, as well as gluconeogenesis was investigated in iron-induced cardiotoxicity. Cardiotoxicity was induced in heart tissues harvested from healthy male SD rats by 0.1 mM FeSO4. Treatment was carried out by co-in...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02227-3
更新日期：2021-03-01 00:00:00
abstract：:Type 2 diabetes is characterized by hyperglycemia and oxidative stress. Hyperglycemia is linked to mitochondrial dysfunction and reduced β-cell mass due to the reduced expression of genes such as Mfn2 as well as the participation of the Bcl2 gene family, responsible for increased apoptosis. The purpose of this study w...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9666-z
更新日期：2013-06-01 00:00:00
abstract：:Hair samples of 134 school children (12-14 yr old) living in three residential zones in the vicinity of a new hazardous waste incinerator (HWI) (Constanti, Tarragona County, Catalonia, Spain) were analyzed by inductively coupled plasma-mass spectrometry (ICP-MS) for arsenic (As), beryllium (Be), cadmium (Cd), chromium...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:104:3:203
更新日期：2005-06-01 00:00:00
