Physiological chromium determination in serum by Zeeman graphite furnace atomic absorption spectrometry. A serious challenge.

Abstract:

:Several authors have already underlined chromium implication in glucose and lipids metabolism of humans. In this field, physiological chromium determination in serum could be helpful, but the discrepancies reported in numerous papers are confusing. Here we report some results obtained by Zeeman correction Graphite Furnace Atomic Absorption Spectrometry. This technique includes a dilution of serum with 12.5 mM ultrapure nitric acid and 0.25% Triton X-100 (final concentrations). Some main features can be outlined: (1) the contamination constitutes a serious drawback and (2) the sensitivity of the technique is critical (characteristic mass found: 1.76 pg/0.0044 A.s). Our results obtained from 27 healthy subjects (2.01 +/- 0.77 nmol/L) agree with most recent studies and indicate that serum chromium level does not seem to be sex-related.

journal_name

Biol Trace Elem Res

authors

Chappuis P,Poupon J,Deschamps JF,Guillausseau PJ,Rousselet F

doi

10.1007/BF02784591

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

85-91

eissn

0163-4984

issn

1559-0720

journal_volume

32

pub_type

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