Zinc Sulfate in Narrow Range as an In Vitro Anti-HSV-1 Assay.

Abstract:

:This report explains the employing of a combination test of traditional cell culture with a quantitative real-time PCR for assessment of the antiviral effect of zinc sulfate (ZnSO4) on herpes simplex virus (HSV)-infected Vero cells. Our evidence showed that the treatment with 0.3 mM ZnSO4 strongly inhibited the replication of virus progeny (MOI 0.001) at least 68-fold less. On the other hand, the IC50 demonstrated that the highest activity of ZnSO4 was at the 0.23 mM concentration.

journal_name

Biol Trace Elem Res

authors

Fani M,Khodadad N,Ebrahimi S,Nahidsamiei R,Makvandi M,Teimoori A,Langari H

doi

10.1007/s12011-019-01728-0

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

410-413

issue

2

eissn

0163-4984

issn

1559-0720

pii

10.1007/s12011-019-01728-0

journal_volume

193

pub_type

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