Effect of Dietary Selenium Deficiency on the Cell Apoptosis and the Level of Thyroid Hormones in Chicken.

Abstract:

:This study assessed the effect of dietary selenium (Se) deficiency on male reproductive function in chicken. A total of 180 Hy-line laying cocks (1 day old; Weiwei) were randomly divided into 2 groups (n = 90) of Se-deficient chickens and control chickens. The control group was fed a basic diet (containing 0.15 mg of Se/kg). The Se-deficient group was fed a Se-deficient corn-soy basal diet (containing 0.033 mg of Se/kg). Fifteen chickens were killed in each group on days 30, 60, and 90, respectively. Then, serum and testes were collected and used in the detection of experimental index. Results indicated that GSH-Px activity and Bcl-2 mRNA level in the testes and thyroidal triiodothyronine (T3) and free triiodothyronine (FT3) levels in serum by dietary Se deficiency were significantly decreased compared to the corresponding control groups. Se deficiency-treated group showed a significant increase in MDA concent, TUNEL-positive cells, and mRNA level of Bax, Caspase3, and p53 in the testes and thyroidal thyroxine (T4), free thyroxine (FT4), and thyroid-stimulating hormone (TSH) levels in serum. Histopathologically, Se deficiency caused impairments in the testes. These results suggested that dietary Se deficiency exerts significant harmful effects on male reproductive organ and that the intrinsic and extrinsic pathways and the upstream regulators such as p53, Bax, and Bcl-2 were all involved in Se deficiency-induced testicular apoptosis.

journal_name

Biol Trace Elem Res

authors

Huang Y,Li W,Xu D,Li B,Tian Y,Zan L

doi

10.1007/s12011-015-0534-x

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

445-452

issue

2

eissn

0163-4984

issn

1559-0720

pii

10.1007/s12011-015-0534-x

journal_volume

171

pub_type

杂志文章,随机对照试验
  • Liver toxicity of thioacetamide is increased by hepatocellular iron overload.

    abstract::An increase in hepatic iron concentration might exacerbate liver injury. However, it is unknown whether hepatic iron overload may exacerbate acute liver injury from various toxins. Therefore, we evaluated how manipulations to increase hepatic iron concentration affected the extent of acute liver injury from thioacetam...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0110-9

    authors: Ackerman Z,Pappo O,Link G,Glazer M,Grozovski M

    更新日期:2015-02-01 00:00:00

  • Heavy Metals in Indigenous Preparations Used for Sex Selection During Pregnancy in India.

    abstract::Indigenous preparations (IPs) have evoked a considerable interest in alleviating infections and chronic diseases and improving wellbeing. While such formulations have been a part of traditional practice in several countries and many have been reviewed scientifically for their claims, several of them until date remain ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1411-1

    authors: Ganguli A,Rai P,Balachandran S,Gupta R,Sharma R,Neogi SB

    更新日期:2019-04-01 00:00:00

  • Promotion of lipid oxidation by selenate and selenite and indicators of lipid peroxidation in the rat.

    abstract::The AIN-93 reformulation of the AIN-76A rodent diet includes a change in selenium supplement from sodium selenite to sodium selenate to reduce dietary lipid peroxidation. A change to selenate as the standard form of Se in rat diets would render results from previous work using selenite less relevant for comparison wit...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:79:3:257

    authors: Moak MA,Christensen MJ

    更新日期:2001-03-01 00:00:00

  • The Alterations of Copper and Zinc Homeostasis in Acute Appendicitis and the Clinical Significance.

    abstract::Copper (Cu) and zinc (Zn) are involved in inflammatory process. This study was to investigate the clinical significance of Cu and Zn homeostasis alterations in acute appendicitis (AA). One hundred twenty-two AA patients and 102 healthy controls were enrolled in this study. Of which, 85 patients' appendixes were collec...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01661-2

    authors: Lin W,Han W,Wen K,Huang S,Tang Y,Lin Z,Han M

    更新日期:2019-12-01 00:00:00

  • Jasmonic acid (JA) acts as a signal molecule in LaCl(3)-induced baicalin synthesis in Scutellaria baicalensis seedlings.

    abstract::Rare earth elements (REEs) have been widely used to increase accumulation of biomass and secondary metabolites in medicinal plants in China. However, very few studies have investigated how REEs mediate secondary metabolism synthesis in medicinal plants. Lanthanum (La), an important REE, is known to improve the accumul...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9379-8

    authors: Zhou J,Fang L,Li X,Guo L,Huang L

    更新日期:2012-09-01 00:00:00

  • Protection from H1N1 influenza virus infections in mice by supplementation with selenium: a comparison with selenium-deficient mice.

    abstract::The present paper describes protective effects of supplemental selenium in mice infected with influenza virus. The effects of supplemental selenium on serum selenium levels, mortality, lung virus titers, and cytokine titers were investigated in mice inoculated intranasally with suspensions of influenza virus. Whereas ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8726-x

    authors: Yu L,Sun L,Nan Y,Zhu LY

    更新日期:2011-06-01 00:00:00

  • Effects of iron glycine chelate on growth, tissue mineral concentrations, fecal mineral excretion, and liver antioxidant enzyme activities in broilers.

    abstract::The study was conducted to determine the effects of iron glycine chelate (Fe-Gly) on growth, tissue mineral concentrations, fecal mineral excretion, and liver antioxidant enzyme activities in broilers. A total of 360 1-day-old commercial broilers (Ross × Ross) were randomly allotted to six dietary treatments with six ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9418-5

    authors: Ma WQ,Sun H,Zhou Y,Wu J,Feng J

    更新日期:2012-11-01 00:00:00

  • Determination of Minerals in Herbal Infusions Promoting Weight Loss.

    abstract::The study aimed at determination of the mineral composition of slimming herbal teas and estimation of the coverage of their total intake with infusions in women's daily diet. The content of Na+, K+, Ca+2, Mg+2, Zn+2, Cu+2, Fe+2, and Mn+2 was determined in infusions and mineralisates obtained from the slimming herbal t...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0790-4

    authors: Samolińska W,Kiczorowska B,Kwiecień M,Rusinek-Prystupa E

    更新日期:2017-02-01 00:00:00

  • The Expression of Zinc Transporters Changed in the Intestine of Weaned Pigs Exposed to Zinc Chitosan Chelate.

    abstract::This study was conducted to investigate the effect of zinc chitosan chelate (CS-Zn) on zinc transporter expression and content of tissue zinc in weaned piglets. A total of 90 weaned pigs (Duroc × Landrace × Yorkshire) were randomly allocated to treatment groups with supplementation of 100 mg/kg zinc as ZnSO4, 100 mg/k...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0732-1

    authors: Lv M,Fu X,Hu L,Yue X,Han X

    更新日期:2016-12-01 00:00:00

  • Trace Elements in the Large Population-Based HUNT3 Survey.

    abstract::The Nord-Trøndelag Health Study (The HUNT Study) is a large health survey population study in the county of Trøndelag, Norway. The survey has been repeated four times in about 10-year intervals. In the HUNT3 survey (2006-2008), we collected 28,000 samples for trace element analysis. Blood samples from 758 healthy pers...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02376-5

    authors: Syversen T,Evje L,Wolf S,Flaten TP,Lierhagen S,Simic A

    更新日期:2020-09-08 00:00:00

  • Dietary Selenium Promotes Somatic Growth of Rainbow Trout (Oncorhynchus mykiss) by Accelerating the Hypertrophic Growth of White Muscle.

    abstract::As a nutritionally essential trace element, selenium (Se) is crucial for fish growth. However, the underlying mechanisms remain unclear. Fish somatic growth relies on the white muscle growth. This study aimed to explore the effects and underlying mechanisms of Se on fish white muscle growth using a juvenile rainbow tr...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02282-w

    authors: Wang L,Zhang D,Li S,Wang L,Yin J,Xu Z,Zhang X

    更新日期:2020-07-14 00:00:00

  • Anti-oxidant supplementation decreases TBA reactants in serum of elderly.

    abstract::An "anti-oxidant cocktail" consisting of betacarotene, vitamins B6, C, E, zinc, and selenium or corresponding placebos were given for one y as daily dietary supplements to 45 elderly residents of a nursing home. Initially, the serum TBA reactant levels were higher (2.7 +/- 0.7 mumol/L) than those of an ad hoc control ...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02795458

    authors: Tolonen M,Sarna S,Halme M,Tuominen SE,Westermarck T,Nordberg UR,Keinonen M,Schrijver J

    更新日期:1988-09-01 00:00:00

  • Synthesis and bioactive studies of complex 8-hydroxyquinolinato-bis-(salicylato) yttrium (III).

    abstract::This paper reports the synthesis of a new bioactive complex, 8-hydroxyquinolinato-bis-(salicylato) yttrium (III) (HSAY), whose composition and structure were characterized by elemental analysis, IR spectra, thermogravimetric analysis, and X-ray diffraction. The power-time curves of the compounds HSAY, C(7)H(6)O(3), C(...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9297-1

    authors: Li X,Li QG,Zhang H,Hu JL,Yao FH,Yang DJ,Xiao SX,Ye LJ,Huang Y,Guo DC

    更新日期:2012-06-01 00:00:00

  • High Content of Lead Is Associated with the Softness of Drinking Water and Raised Cardiovascular Morbidity: A Review.

    abstract::Daily ingestion of lead (Pb), even through piped drinking water, has long time been an important issue of concern, attracting for decades research in environmental science and toxicology, and again comes to prominence because of recent high-profile cases of exposure of populations in several countries to Pb-contaminat...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/s12011-018-1336-8

    authors: Bjørklund G,Dadar M,Chirumbolo S,Aaseth J

    更新日期:2018-12-01 00:00:00

  • Fluoride Content in Alcoholic Drinks.

    abstract::The aim of the study was to determine the role of alcoholic drinks as a potential source of dietary fluoride by means of measuring fluoride levels in selected alcoholic drinks available on the Polish market that are also diverse in terms of the percentage content of ethanol. The study was conducted on 48 types of drin...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0519-9

    authors: Goschorska M,Gutowska I,Baranowska-Bosiacka I,Rać ME,Chlubek D

    更新日期:2016-06-01 00:00:00

  • The alteration of miR-222 and its target genes in nickel-induced tumor.

    abstract::Nickel is an important kind of metal and a necessary trace element in people's production and livelihood; it is also a well-confirmed human carcinogen. In the past few years, researchers did a large number of studies about the molecular mechanisms of nickel carcinogenesis, and they focused on activation of proto-oncog...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9619-6

    authors: Zhang J,Zhou Y,Ma L,Huang S,Wang R,Gao R,Wu Y,Shi H,Zhang J

    更新日期:2013-05-01 00:00:00

  • Effects of Ni(2+), Co(2+), and Mn(2+) on desensitized butyrylcholinesterase prepared from human serum.

    abstract::Human serum butyrylcholinesterase (BChE) has been converted into a stable but less active desensitized form when heated at 45 degrees C for 24 h. The desensitized BChE follows Michaelis-Menten kinetics, whereas native enzyme exhibits slightly negative cooperativity with respect to butyrylthiocholine binding. In this s...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:93:1-3:55

    authors: Cengiz D,Cokugras AN,Tezcan EF

    更新日期:2003-07-01 00:00:00

  • Metabolism of methylmercury in rabbits and hamsters.

    abstract::The metabolism of 203Hg-labeled methylmercury chloride (MeHg) has been studied in rabbits and hamsters. Rabbits were administered 1.6 mumols MeHgCl/kg bw intravenously, and hamsters 40 mumols/kg bw orally. Urine and feces were collected daily and groups of four animals killed after 1 h, 1 d, or 7 d. The concentration ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917256

    authors: Petersson K,Dock L,Vahter M

    更新日期:1989-07-01 00:00:00

  • Effects of alpha-tocopherol on serum trace and major elements in rats with bleomycin-induced pulmonary fibrosis.

    abstract::The study was undertaken to investigate the influence of alpha-tocopherol on zinc, copper, iron, calcium, magnesium, and potassium concentrations in serum of rats with bleomycin-induced pulmonary fibrosis. Fourteen Wistar albino rats were randomly divided into two groups of seven animals each. The first group was trea...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:114:1:175

    authors: Dede S,Mert H,Mert N,Yur F,Ertekin A,Deger Y

    更新日期:2006-01-01 00:00:00

  • The effect of selenium and vitamin E on microvascular permeability of rat organs.

    abstract::The effects of dietary sodium selenite and vitamin E on the microvascular permeability of rat organs such as heart, brain, kidney, liver and eye were investigated by using the Evans blue leakage method. Combined deficiency of selenium and vitamin E caused an increase in the permeability of the heart and eye with respe...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783332

    authors: Demirel-Yilmaz E,Dinçer D,Yilmaz G,Turan B

    更新日期:1998-07-01 00:00:00

  • Suppressor Effects of Sodium Pentaborate Pentahydrate and Pluronic F68 on Adipogenic Differentiation and Fat Accumulation.

    abstract::Obesity is a major public health problem worldwide and a risk factor for certain diseases, including cardiovascular disease, diabetes, cancer, and depression. Unfortunately, currently available anti-obesity drugs have failed in the long-term maintenance of weight control. It has been a challenge to design novel drugs ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01738-y

    authors: Yilmaz AB,Tapsin S,Elbasan EB,Kayhan HD,Sahin F,Turkel N

    更新日期:2020-02-01 00:00:00

  • Smoking does not influence cadmium concentrations in blood and urine in relatively high levels of environmental cadmium areas in Japan.

    abstract::We examined how the influence of smoking on blood and urinary cadmium (Cd) concentrations was modified by the level of environmental Cd. We measured blood and urinary Cd concentrations of 1134 men over 50 yr of age in three areas in Japan that were exposed to different levels of environmental Cd. Analysis of variance ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:110:2:107

    authors: Uetani M,Kobayashi E,Suwazono Y,Nishijo M,Nakagawa H,Kido T,Nogawa K

    更新日期:2006-05-01 00:00:00

  • Effect of zinc on aminopeptidase N activity and L-threonine transport in rabbit jejunum.

    abstract::Zinc is a nutritionally essential trace element required for many biological functions to be successfully carried out. The aim of the present work was to study the influence of zinc on the intestinal absorption of L-threonine and on the aminopeptidase N activity in rabbit jejunum, after in vitro addition and/or oral a...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02784557

    authors: Rodriguez Yoldi MC,Mesonero JE,Rodriguez Yoldi MJ

    更新日期:1996-07-01 00:00:00

  • Supplementation with selenium augments the functions of natural killer and lymphokine-activated killer cells.

    abstract::This study examined the effects of dietary (2.0 ppm for 8 wk) and in vitro (1 x 10(-7)M) supplementation with selenium (Se, as sodium selenite) on the activity of spleen natural killer (NK) cells and plastic-adherent lymphokine-activated killer (A-LAK) cells from C57B1/6J male mice. Dietary supplementation with Se res...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02789164

    authors: Kiremidjian-Schumacher L,Roy M,Wishe HI,Cohen MW,Stotzky G

    更新日期:1996-06-01 00:00:00

  • ICP-MS Assessment of Hair Essential Trace Elements and Minerals in Russian Preschool and Primary School Children with Attention-Deficit/Hyperactivity Disorder (ADHD).

    abstract::The objective of the present study was to investigate the relationship between hair essential trace element and mineral content and ADHD in preschool (4-6 years old) and primary school children (6-10 years old) in relation to age and gender. Hair essential trace element and mineral content in 90 Russian children with ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01947-5

    authors: Tinkov AA,Mazaletskaya AL,Ajsuvakova OP,Bjørklund G,Huang PT,Chernova LN,Skalny AA,Skalny AV

    更新日期:2020-08-01 00:00:00

  • Relationship between serum nickel and homocysteine concentration in hemodialysis patients.

    abstract::Severe hyperhomocysteinemia (HHC) is associated with atherosclerosis. In hemodialysis (HD) patients, one of the main causes of death is cardiovascular disease. In animals, trace elements such as cobalt, copper, iron, and nickel ameliorated vitamin B(12) deficiency-induced HHC. However, correlations between plasma tota...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-008-8139-2

    authors: Katko M,Kiss I,Karpati I,Kadar A,Matyus J,Csongradi E,Posta J,Paragh G,Balla J,Kovacs B,Varga Z

    更新日期:2008-09-01 00:00:00

  • Effect of zinc supplementation on antioxidant activity in young wrestlers.

    abstract::This study aims to examine the effect of zinc supplementation on free-radical formation and antioxidant system in individuals who are actively engaged in wrestling as a sport. The study registered a total of 40 male subjects, of whom 20 were wrestlers and 20 were sedentary individuals. The subjects were equally alloca...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-009-8457-z

    authors: Kara E,Gunay M,Cicioglu I,Ozal M,Kilic M,Mogulkoc R,Baltaci AK

    更新日期:2010-04-01 00:00:00

  • Diversity of inorganic arsenite biotransformation.

    abstract::Biotransformation of inorganic arsenic in mammals is catalyzed by three serial enzyme activities: arsenate reductase, arsenite methyltransferase, and monomethylarsonate methyltransferase. Our laboratory has purified and characterized these enzymes in order to understand the mechanisms and elucidate the variations of t...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/BF02783907

    authors: Healy SM,Wildfang E,Zakharyan RA,Aposhian HV

    更新日期:1999-06-01 00:00:00

  • Chromosomal aberrations induced by cobaltous chloride in mice in vivo.

    abstract::The effects of cobaltous chloride in inducing chromosomal aberrations were observed on laboratory bred mice in vivo after single oral administration of different fractions (1/10, 1/20, 1/40) of the lethal toxic dose of the salt. Bone marrow cells were flushed out and processed for chromosome studies following colchici...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF03032691

    authors: Palit S,Sharma A,Talukder G

    更新日期:1991-05-01 00:00:00

  • Heavy Metals Level, Health Risk Assessment Associated with Contamination of Black Tea; A Case Study from Khyber Pakhtunkhwa (KPK), Pakistan.

    abstract::In the present study, 15 different commercial tea brands sold in Khyber Pakhtunkhwa were collected from the markets. The samples were analyzed for the concentrations of ten selected heavy metals. The metal concentration showed a random distribution in all samples. The mean concentration of Cd, Cu, Mn, Pb, Zn, and Fe w...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02059-1

    authors: Idrees M,Jan FA,Hussain S,Salam A

    更新日期:2020-11-01 00:00:00