Smoking does not influence cadmium concentrations in blood and urine in relatively high levels of environmental cadmium areas in Japan.


:We examined how the influence of smoking on blood and urinary cadmium (Cd) concentrations was modified by the level of environmental Cd. We measured blood and urinary Cd concentrations of 1134 men over 50 yr of age in three areas in Japan that were exposed to different levels of environmental Cd. Analysis of variance was used to compare Cd concentrations in blood and urine of smokers with those of nonsmokers living in the three areas. Correlation coefficients between the number of cigarettes smoked per day or smoking indices (the number of cigarettes smoked per day multiplied by the number of years smoked) and blood and urinary Cd concentrations were calculated. No significant difference in Cd concentrations between smokers and nonsmokers was observed in areas where the average Cd concentration in blood was over approx 2.4 ng/g, 2.0 mug/L in urine, and 2.3 mug/g creatinine in urine, respectively. Therefore, it was suggested that an influence of smoking on blood and urinary Cd concentrations was not observed in areas exposed to relatively high levels of environmental Cd.


Biol Trace Elem Res


Uetani M,Kobayashi E,Suwazono Y,Nishijo M,Nakagawa H,Kido T,Nogawa K




Has Abstract


2006-05-01 00:00:00














  • Investigating the Essentiality and Requirements of Iron from the Ancient to the Present.

    abstract::This review discusses the development of studies that evaluated the essentiality and requirements of iron from the ancient to the present. The therapeutic effects of iron compounds were recognized by the ancient Greeks and Romans. The earliest recognition of the essentiality of iron was stated by Paracelsus, a disting...

    journal_title:Biological trace element research

    pub_type: 历史文章,杂志文章,评审


    authors: Yokoi K

    更新日期:2019-03-01 00:00:00

  • Clinical effects of cesium intake.

    abstract::The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However, no properly confirmed tumor regression was reported so...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审


    authors: Melnikov P,Zanoni LZ

    更新日期:2010-06-01 00:00:00

  • The Effect of Exposure to Cd and Pb in the Form of a Drinking Water or Feed on the Accumulation and Distribution of These Metals in the Organs of Growing Wistar Rats.

    abstract::The degree of accumulation and distribution of Cd and Pb in the organs of young animals compared to the amount taken in with water or feed have not been thoroughly investigated yet. The experiment aimed to verify whether the source of toxic metals (feed, drinking water) administered to growing rats orally has an influ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Winiarska-Mieczan A,Kwiecień M

    更新日期:2016-02-01 00:00:00

  • Cadmium uptake, translocation, and tolerance in AHA1OX Arabidopsis thaliana.

    abstract::Information on cadmium (Cd) uptake and transport is essential to understand better the physiology of Cd tolerance in plants. In this study, Cd uptake, translocation, and tolerance were investigated in AHA1 (Arabidopsis plasma membrane H(+)-ATPase gene) overexpressed plants. Exposed to 10 µM CdCl(2), AHA1OX showed a hi...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Hou L,Shi W,Wei W,Shen H

    更新日期:2011-02-01 00:00:00

  • Delineation of the Residues of Bacillus anthracis Zinc Uptake Regulator Protein Directly Involved in Its Interaction with Cognate DNA.

    abstract::Zinc uptake regulator (Zur) is a negative transcriptional regulator of bacteria that belongs to the FUR superfamily of proteins and regulates zinc (Zn) homeostasis under extreme Zn conditions. The Zur protein of Bacillus anthracis (BaZur) was though characterized previously, but the residues of this transcriptional re...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kandari D,Joshi H,Tanwar N,Munde M,Bhatnagar R

    更新日期:2020-10-14 00:00:00

  • Presence of Toxic Heavy Metals in Platelet-Rich Fibrin: a Pilot Study.

    abstract::Platelet-rich fibrin (PRF) is widely used blood-derived biomaterial which is directly applied to the surgical wounds. Depending on its autologous origin, PRF is thought as a safe material. However, it is not known to what extent the blood-derived toxins can be found in the PRF by considering the systemic exposure rate...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Yaprak E,Yolcubal İ

    更新日期:2019-10-01 00:00:00

  • Mercury from maternal "silver" tooth fillings in sheep and human breast milk. A source of neonatal exposure.

    abstract::Neonatal uptake of mercury (Hg) from milk was examined in a pregnant sheep model, where radioactive mercury (Hg203)/silver tooth fillings (amalgam) were newly placed. A crossover experimental design was used in which lactating ewes nursed foster lambs. In a parallel study, the relationship between dental history and b...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Vimy MJ,Hooper DE,King WW,Lorscheider FL

    更新日期:1997-02-01 00:00:00

  • An estimation of the manganese requirement for broilers from 1 to 21 days of age.

    abstract::A dose-response experiment was conducted to find the sensitive and consistent biomarker for the estimation of dietary manganese (Mn) requirement and establish the optimal Mn level for broilers fed a practical corn-soybean meal diet from 1 to 21 days of age post-hatching. A total of 480 1-day-old Arbor Acres male chick...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Li S,Lin Y,Lu L,Xi L,Wang Z,Hao S,Zhang L,Li K,Luo X

    更新日期:2011-11-01 00:00:00

  • Factors influencing plasma zinc levels in low-income pregnant women.

    abstract::Plasma zinc (Zn) concentrations were measured in 4376 indigent women (86% African-American), at at mean (+/- SD) gestational age of 15 (+/- 7.8) wk to determine the relationship between various maternal characteristics and plasma Zn levels during pregnancy. Mean Plasma An levels were lower in African-American women th...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Neggers YH,Dubard MB,Goldenberg RL,Tamura T,Johnston KE,Copper RL,Hauth JC

    更新日期:1996-10-01 00:00:00

  • An interaction between selenate and a sulfate transporter in the lactating rat mammary gland.

    abstract::The efficacy of selenate and other divalent anions to stimulate the efflux of radiolabeled sulfate from lactating rat mammary tissue slices has been examined. Both selenate and sulfate markedly increased the fractional release of sulfate via a system that is temperature-sensitive and sensitive to the anion-exchange in...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Shennan DB,McNeillie SA

    更新日期:1990-03-01 00:00:00

  • High accumulations of calcium and phosphorus in women's pubic symphysis.

    abstract::To elucidate compositional changes of the pubic symphysis (PS) by aging, elements of pubic symphysis (PSs) removed from 26 cadavers were determined by inductively coupled plasma atomic-emission spectrometry. It was found that the relative contents (RCs) of calcium and phosphorus in women's PSs were about three- and fi...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Tohno S,Tohno Y,Minami T,Okazaki Y,Utsumi M,Moriwake Y,Nishiwaki F,Yamada M

    更新日期:1997-01-01 00:00:00

  • A Quantitative Assessment and Biomagnification of Mercury and Its Associated Health Risks from Fish Consumption in Freshwater Lakes of Azad Kashmir, Pakistan.

    abstract::Issues regarding biomagnification of mercury (Hg) due to its persistence, bioaccumulation, and toxicity in freshwater lakes have gained much attention in the last two decades especially in remote regions of the world where anthropogenic inputs are considered as negligible. In this study, spatial distribution of total ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Hina N,Riaz R,Ali U,Rafique U,Malik RN

    更新日期:2021-01-07 00:00:00

  • The Toxicological Analysis of Ni and Cr in Prescription Food for Special Medical Purposes and Modified Milk Products for Babies in Infancy Available in Pharmacies in Poland.

    abstract::Prescription food for special medical purposes (FSMPs) and modified milk products (MMPs) for babies in the infancy period available in pharmacies are increasingly frequently used for newborns and infants-especially in cases where allergies and food-borne diseases are diagnosed. However, there is a lack of scientific s...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Jurowski K,Krośniak M,Fołta M,Tatar B,Cole M,Piekoszewski W

    更新日期:2019-12-01 00:00:00

  • Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers.

    abstract::Hyperlipidemia is one of the major risk factors for atherosclerosis and ischemic heart disease. Chromium (Cr) mineral is playing a crucial role in glucose and lipid homeostasis. The aim of this study was to evaluate the protective effects of combined chromium picolinate (CrPic) and atorvastatin treatment against hyper...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Shafik NM,Baalash A,Ebeid AM

    更新日期:2017-12-01 00:00:00

  • Estimation of Trace Elements, Antioxidants, and Antibacterial Agents of Regularly Consumed Indian Medicinal Plants.

    abstract::Nutritional profile of minerals and antioxidants in Indian spice extracts was evaluated in order to examine their efficacy in treating various diseases, disorders, and allergies in human health. Extracts of four medicinal plants such as Curcuma longa, Zingiber officinale, Piper nigrum, and Piper longum, regularly cons...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Swain S,Rautray TR

    更新日期:2021-03-01 00:00:00

  • Plasma levels of trace elements have an implication on interferon treatment of children with chronic hepatitis B infection.

    abstract::This study evaluated the plasma levels of trace elements in children with chronic hepatitis B virus (HBV) infection and assessed whether they can be a factor that affects the response to interferon alpha (IFN-alpha) treatment. The study included 35 cases (ten girls, 25 boys) aged 3-13 years with chronic HBV infection ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Balamtekin N,Kurekci AE,Atay A,Kalman S,Okutan V,Gokcay E,Aydin A,Sener K,Safali M,Ozcan O

    更新日期:2010-06-01 00:00:00

  • Preliminary study on the relationship between osteoporosis and trace elements with rat models.

    abstract::Thirty rats were divided randomly into five groups and fed with different feeds. They were killed after 2 mo. Right thighs of these rats were taken as samples. Bone mineral densities of these samples were measured by the double-energy x-ray bone mineral densitometer, and trace elements contents of the samples were ana...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Nie H,Qin L,Tian W,Ni B,Bao A,Wang P

    更新日期:1999-01-01 00:00:00

  • Supplementation with selenium augments the functions of natural killer and lymphokine-activated killer cells.

    abstract::This study examined the effects of dietary (2.0 ppm for 8 wk) and in vitro (1 x 10(-7)M) supplementation with selenium (Se, as sodium selenite) on the activity of spleen natural killer (NK) cells and plastic-adherent lymphokine-activated killer (A-LAK) cells from C57B1/6J male mice. Dietary supplementation with Se res...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kiremidjian-Schumacher L,Roy M,Wishe HI,Cohen MW,Stotzky G

    更新日期:1996-06-01 00:00:00

  • Effects of Nano-copper on Antioxidant Function in Copper-Deprived Guizhou Black Goats.

    abstract::Guizhou black goats are essential to the production system in the Wumeng prairie in the Western China. This study aimed to determine the influence of nano-copper on antioxidant system in copper-deprived Guizhou black goats. We analyzed mineral contents in soil, forage, and goats' tissues. Blood parameters were also de...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Shen X,Song C,Wu T

    更新日期:2020-08-18 00:00:00

  • Zinc, ethanol, and lipid peroxidation in adult and fetal rats.

    abstract::Studies were performed on adult and fetal rats receiving either a zinc-deficient (<0.5 ppm) diet and/or ethanol (20%) throughout pregnancy. Liver zinc levels were depressed in fetuses exposed toin utero zinc deficiency, but brain zinc levels were unchanged. Ethanol had no effect on the concentration of zinc in the sev...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Dreosti IE,Partick EJ

    更新日期:1987-12-01 00:00:00

  • Modulation of testicular and whole blood trace element concentrations in conjunction with testosterone release following kisspeptin administration in male rabbits (Oryctolagus cuniculus).

    abstract::The present study investigated the role of kisspeptin-10 on reproductively significant trace elements in relation to testosterone release in male rabbits, Oryctolagus cuniculus. Groups of rabbits were exposed to single 1 μg kisspeptin dose (i.v., saphenous vein), while simultaneous groups were pretreated with a kisspe...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Qureshi IZ,Abbas Q

    更新日期:2013-08-01 00:00:00

  • Trivalent Chromium has no Effect on Delaying Azoxymethane-Induced Colorectal Cancer in FVB/NJ Mice.

    abstract::As Cr(III) compounds have been shown to increase insulin sensitivity and decrease plasma cholesterol and triglycerides in rodent models of diabetes and insulin resistance and as colorectal cancer risk has been associated with insulin resistance and diabetes, the effects of the Cr(III) compound Cr3 ([Cr3O(O2CCH2CH3)6(H...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: White PE,Deng G,Kuykendall MK,Tadros AM,Dyroff SL,Honan RE,Robertson PM,Vincent JB,Rasco JF

    更新日期:2015-11-01 00:00:00

  • Selenium Prevents Lead-Induced Necroptosis by Restoring Antioxidant Functions and Blocking MAPK/NF-κB Pathway in Chicken Lymphocytes.

    abstract::Recent studies have identified a new existence of a genetically programmed and regulated cell death characterized by necrotic cell death morphology, termed necroptosis. Lead (Pb) is a ubiquitously distributed environmental pollutant that is highly toxic to animals and human beings. However, no detailed report has been...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Zhang J,Hao X,Xu S

    更新日期:2020-12-01 00:00:00

  • Zinc and copper levels in severe heart failure and the effects of atrial fibrillation on the zinc and copper status.

    abstract::Oxidative stress is involved in the pathogenesis of congestive heart failure (CHF). Some trace elements serve as antioxidant defenses. The purpose of this study was to analyze the effect of atrial fibrillation (AF) on zinc (Zn) and copper (Cu) levels in patients with advanced CHF. In this prospective study, serum Zn a...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Ghaemian A,Salehifar E,Jalalian R,Ghasemi F,Azizi S,Masoumi S,Shiraj H,Mohammadpour RA,Bagheri GA

    更新日期:2011-12-01 00:00:00

  • The Selenylation Modification of Epimedium Polysaccharide and Isatis Root Polysaccharide and the Immune-enhancing Activity Comparison of Their Modifiers.

    abstract::Epimedium polysaccharide (EPS) and isatis root polysaccharide (IRPS) were extracted, purified, and selenizingly modified by nitric acid-sodium selenite method to obtain nine selenizing EPSs (sEPSs), sEPS1-sEPS9 and nine selenizing IRPSs (sIRPSs), sIRPS1-sIRPS9, respectively. Their effects on chicken peripheral lymphoc...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Li X,Hou R,Yue C,Liu J,Gao Z,Chen J,Lu Y,Wang D,Liu C,Hu Y

    更新日期:2016-05-01 00:00:00

  • Compositional changes of human mitral valves with aging.

    abstract::To elucidate compositional changes of the mitral valve with aging, the authors investigated the relationships among element contents in the mitral valves. The subjects consisted of 10 men and 15 women, ranging in age from 65 to 102 yr. After the ordinary dissection, mitral valves, lower parts of the interventricular s...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Tohno Y,Tohno S,Satoh H,Minami T,Moriwake Y,Azuma C,Ohnishi Y

    更新日期:2002-09-01 00:00:00

  • The effect of aging on the mineral status of female SAMP1 and SAMR1.

    abstract::The effect of aging on the status of macrominerals and trace elements in tissues was studied using two strains (SAMP1 and SAMR1) of senescence accelerated mouse. Two-month-old, 6-mo-old, and 10-mo-old female SAMP1 and SAMR1 mice were fed a commercial diet. Iron, zinc, copper, calcium, magnesium, phosphorus, sulfur, so...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Morita A,Abdireyim D,Kimura M,Itokawa Y

    更新日期:2001-04-01 00:00:00

  • Comparison of whole blood selenium values and erythrocyte glutathione peroxidase activities of normal individuals on supplementation with selenate, selenite, L-selenomethionine, and high selenium yeast.

    abstract::The selenium levels and the glutathione peroxidase activity GSH-PX of whole blood and of erythrocytes, respectively, were determined in 139 normal Danes and related to sex and smoking habits. No differences were found in relation to sex apart from a higher GSH-PX activity of females when assayed with tertiary butyl hy...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章


    authors: Clausen J,Nielsen SA

    更新日期:1988-01-01 00:00:00

  • Impact of methimazole treatment on magnesium concentration and lymphocytes activation in adolescents with Graves' disease.

    abstract::The aim of this research was to assess plasma magnesium (Mg) concentration, the frequencies of activated T CD4+ and T CD8+ lymphocytes and B lymphocytes in adolescents with hyperthyroidism due to Graves' disease (GD), and to assess changes in the above-mentioned parameters during methimazole (MMI) treatment. The frequ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Klatka M,Grywalska E,Partyka M,Charytanowicz M,Rolinski J

    更新日期:2013-06-01 00:00:00

  • The alteration of miR-222 and its target genes in nickel-induced tumor.

    abstract::Nickel is an important kind of metal and a necessary trace element in people's production and livelihood; it is also a well-confirmed human carcinogen. In the past few years, researchers did a large number of studies about the molecular mechanisms of nickel carcinogenesis, and they focused on activation of proto-oncog...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Zhang J,Zhou Y,Ma L,Huang S,Wang R,Gao R,Wu Y,Shi H,Zhang J

    更新日期:2013-05-01 00:00:00