Smoking does not influence cadmium concentrations in blood and urine in relatively high levels of environmental cadmium areas in Japan.


:We examined how the influence of smoking on blood and urinary cadmium (Cd) concentrations was modified by the level of environmental Cd. We measured blood and urinary Cd concentrations of 1134 men over 50 yr of age in three areas in Japan that were exposed to different levels of environmental Cd. Analysis of variance was used to compare Cd concentrations in blood and urine of smokers with those of nonsmokers living in the three areas. Correlation coefficients between the number of cigarettes smoked per day or smoking indices (the number of cigarettes smoked per day multiplied by the number of years smoked) and blood and urinary Cd concentrations were calculated. No significant difference in Cd concentrations between smokers and nonsmokers was observed in areas where the average Cd concentration in blood was over approx 2.4 ng/g, 2.0 mug/L in urine, and 2.3 mug/g creatinine in urine, respectively. Therefore, it was suggested that an influence of smoking on blood and urinary Cd concentrations was not observed in areas exposed to relatively high levels of environmental Cd.


Biol Trace Elem Res


Uetani M,Kobayashi E,Suwazono Y,Nishijo M,Nakagawa H,Kido T,Nogawa K




Has Abstract


2006-05-01 00:00:00














  • Selenium and glutathione peroxidase mRNA in rat glioma.

    abstract::The purpose of current study was to determine the step at which dietary selenium (Se) regulates the transcriptional expression of the gene for Se-glutathione peroxidase (Se-GPx) in rat brain and transplanted glioma tissue. Wistar rats were fed a Se-free diet or the same diet supplemented with 0.5, 2.0, and 4.0 mg Se/k...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Zhang Z,Miyatake S,Saiki M,Asahi M,Yukawa H,Toda H,Kikuchi H,Yoshimura SI,Hashimoto N

    更新日期:2000-01-01 00:00:00

  • Biological evaluation of trace element data in human ovaries by statistical analysis.

    abstract::Analysis of variance, analysis of covariance, correlation coefficient, multiple correlation, and partial correlation coefficient statistical tests were applied to Cs, Cr, Co, Fe, Rb, Sc, Se, and Zn content in human ovaries in order to evaluate statistically the possible relationships between these trace elements at: t...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kanias GD,Kouri E

    更新日期:1996-04-01 00:00:00

  • Lipid peroxidation in rats administrated with mercuric chloride.

    abstract::Parenteral administration of mercuric chloride (HgCl2) to rats enhanced lipid peroxidation in liver, kidney, lung, testis, and serum (but not in heart, spleen, or muscle), as measured by the thiobarbituric acid reaction for malondialdehyde (MDA) in fresh tissue homogenates and body fluids. After sc injection of HgCl2 ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Huang YL,Cheng SL,Lin TH

    更新日期:1996-05-01 00:00:00

  • Delineation of the Residues of Bacillus anthracis Zinc Uptake Regulator Protein Directly Involved in Its Interaction with Cognate DNA.

    abstract::Zinc uptake regulator (Zur) is a negative transcriptional regulator of bacteria that belongs to the FUR superfamily of proteins and regulates zinc (Zn) homeostasis under extreme Zn conditions. The Zur protein of Bacillus anthracis (BaZur) was though characterized previously, but the residues of this transcriptional re...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kandari D,Joshi H,Tanwar N,Munde M,Bhatnagar R

    更新日期:2020-10-14 00:00:00

  • DNA fragmentation, caspase 3 and prostate-specific antigen genes expression induced by arsenic, cadmium, and chromium on nontumorigenic human prostate cells.

    abstract::Prostate cancer is one of the most common cancers and the second cause of cancer-related deaths among men. Metals are recognized as chemical carcinogens where chronic exposures to such metals are implicated in the development of cancer, including prostate cancer. This in vitro study demonstrates the relative death sen...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: El-Atta HM,El-Bakary AA,Attia AM,Lotfy A,Khater SS,Elsamanoudy AZ,Abdalla HA

    更新日期:2014-12-01 00:00:00

  • Dose- and time-dependent effects of luteolin on liver metallothioneins and metals in carbon tetrachloride-induced hepatotoxicity in mice.

    abstract::The aim of this study was to investigate the protective effect of luteolin on liver Ca, Mg, Zn, Cu, Fe, and Mn content in mice with carbon tetrachloride (CCl4)-induced hepatotoxicity. Additionally, liver metallothionein (MT) expression was studied. Luteolin was administered intraperitoneally (i.p.) as a single 5- or 5...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Domitrović R,Jakovac H,Grebić D,Milin C,Radosević-Stasić B

    更新日期:2008-01-01 00:00:00

  • Distributional pattern of zinc, cadmium, mercury, and selenium in livers of hooded seal (Cystophora cristata).

    abstract::The liver of Hooded Seal (Cystophora cristata) consists of six lobes of unequal sizes. Extensive sampling by means of cutout samples covering the depth horizon 2-30 mm below liver surface indicates that the liver may be considered homogeneous as to concentrations of zinc, cadmium, mercury, and selenium (residuals of o...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Nielsen CO,Dietz R

    更新日期:1990-01-01 00:00:00

  • Stimulation of fibroblast proliferation by insoluble gadolinium salts.

    abstract::The purpose of this study was to assess insoluble salts containing gadolinium (Gd(3+)) for effects on human dermal fibroblasts. Responses to insoluble Gd(3+) salts were compared to responses seen with Gd(3+) solubilized with organic chelators, as in the Gd(3+)-based contrast agents (GBCAs) used for magnetic resonance ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Bleavins K,Perone P,Naik M,Rehman M,Aslam MN,Dame MK,Meshinchi S,Bhagavathula N,Varani J

    更新日期:2012-02-01 00:00:00

  • Functionalized Core-Shell Yttrium Oxide Nanoparticles as Antioxidants Agents in Heat Stressed Rats.

    abstract::Herein, we assess the antioxidant potential of core-shell yttrium oxide nanoparticles functionalized with ethylene glycol methacrylate phosphate (EGMP). The antioxidant properties of these nanoparticles were investigated in heat stressed models of 21 rats (heat stressed group, group B). Different samples of blood, ser...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kassem S,Mohamed M,Sayour H,Canfarotta F,Piletsky S,Soliman MAM

    更新日期:2020-11-01 00:00:00

  • Oxidative Damage Induced by Nano-titanium Dioxide in Rats and Mice: a Systematic Review and Meta-analysis.

    abstract::Nano-titanium dioxide is a kind of widely used nanomaterial that exhibits various adverse outcomes. However, the role of oxidative stress in this regard remains controversial. This study aimed to evaluate whether oxidative stress is one of the toxicity mechanisms induced by nano-titanium dioxide in rats and mice model...

    journal_title:Biological trace element research

    pub_type: 杂志文章,meta分析


    authors: An H,Ling C,Xu M,Hu M,Wang H,Liu J,Song G,Liu J

    更新日期:2020-03-01 00:00:00

  • Zinc deficiency decreases the activity of calmodulin regulated cyclic nucleotide phosphodiesterases in vivo in selected rat tissues.

    abstract::The effect of zinc deficiency on calmodulin function was investigated by assessing the in vivo activity of two calmodulin regulated enzymes, adenosine 3',5'-monophosphate (c-AMP) and guanosine 3',5'-monophosphate (c-GMP) phosphodiesterase (PDE) in several rat tissues. Enzymatic activities in brain, heart, and testis o...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Law JS,McBride SA,Graham S,Nelson NR,Slotnick BM,Henkin RI

    更新日期:1988-08-01 00:00:00

  • Fluoride affects calcium homeostasis and osteogenic transcription factor expressions through L-type calcium channels in osteoblast cell line.

    abstract::Osteoblast L-type voltage-dependent calcium channels (VDCC) play important roles in maintaining intracellular homeostasis and influencing multiple cellular processes. In particular, they contribute to the activities and functions of osteoblasts (OBs). In order to study how L-type VDCC modulate calcium ion (Ca(2+)) hom...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Duan XQ,Zhao ZT,Zhang XY,Wang Y,Wang H,Liu DW,Li GS,Jing L

    更新日期:2014-12-01 00:00:00

  • Comparative in situ study of the intestinal absorption of aluminum, manganese, nickel, and lead in rats.

    abstract::This comparative study of the intestinal absorption of four toxic metals (aluminum, manganese, nickel, and lead) carried out in rats using the in situ intestinal perfusion technique was able to measure the partition of each metal between the intestine (intestinal retention), the blood circulation, and target tissues a...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Arnich N,Cunat L,Lanhers MC,Burnel D

    更新日期:2004-07-01 00:00:00

  • Zinc, copper, and zinc- or copper-dependent enzymes in human hypertension.

    abstract::Imbalance of zinc and copper status has been hypothesized in human hypertension. A case-control study was carried out to elucidate the possible relationship between zinc and copper status and essential hypertension. Thirty-one subjects affected by mild stable hypertension, pharmacologically untreated, were investigate...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Vivoli G,Bergomi M,Rovesti S,Pinotti M,Caselgrandi E

    更新日期:1995-08-01 00:00:00

  • Metal determination by EDXRF in lichens. A contribution to pollutants monitoring.

    abstract::Samples of Evernia prunastri, collected in a mountainous zone, were exposed in urban and highly industrialized areas in order to monitor the atmospheric pollution. Amounts of Cr, Mn, Fe, Ni, Cu, Zn, and Pb were determined by EDXRF spectrometry in secondary target excitation mode and in the thin film approach. An incre...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Caniglia G,Calliari I,Celin L,Tollardo AM

    更新日期:1994-10-01 00:00:00

  • Selenium Overcomes Doxorubicin Resistance in Their Nano-platforms Against Breast and Colon Cancers.

    abstract::Colon cancer in men and breast cancer in women are regarded as major health burdens, accounting for majority of cancer diagnoses globally. Doxorubicin (DOX) resistance in breast and colon cancers represents the main reason of unsuccessful therapy. The rationale of this study is to explore whether selenium nanoparticle...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Abd-Rabou AA,Ahmed HH,Shalby AB

    更新日期:2020-02-01 00:00:00

  • Increased oxidative stress and altered levels of nitric oxide and peroxynitrite in Tunisian patients with chronic obstructive pulmonary disease: correlation with disease severity and airflow obstruction.

    abstract::This study was aimed to evaluate the oxidant-antioxidant imbalance in the pathogenesis of chronic obstructive pulmonary disease (COPD) in Tunisians. We assessed 16 parameters related to the oxidative status that include malondialdehyde (MDA), total protein carbonyls (PCs), and advanced oxidation protein products (AOPP...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: ben Anes A,Fetoui H,Bchir S,ben Nasr H,Chahdoura H,Chabchoub E,Yacoub S,Garrouch A,Benzarti M,Tabka Z,Chahed K

    更新日期:2014-10-01 00:00:00

  • Effect of Selenium from Selenium-Enriched Kale Sprout Versus Other Selenium Sources on Productivity and Selenium Concentrations in Egg and Tissue of Laying Hens.

    abstract::A 6-week trial was conducted to compare the effect of selenium (Se) from hydroponically produced Se-enriched kale sprout (HPSeKS), sodium selenite (SS), and Se-enriched yeast (SeY) in laying hens. A total of 144 40-week-old hens were randomly divided into four groups, according to a completely randomized design. Each ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Chantiratikul A,Chinrasri O,Chantiratikul P

    更新日期:2018-03-01 00:00:00

  • Evaluation of hypoglycemic activity of inorganic constituents in Nelumbo nucifera seeds on streptozotocin-induced diabetes in rats.

    abstract::The seeds of Nelumbo nucifera (Lotus) have been used in the traditional system of medicine for various ailments including diabetes. The present study was aimed at analyzing the levels of biologically important trace elements in the lotus seeds by atomic absorption spectroscopy and evaluating the hypoglycemic propertie...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Mani SS,Subramanian IP,Pillai SS,Muthusamy K

    更新日期:2010-12-01 00:00:00

  • Effect of nitrous oxide on nickel deprivation in rats.

    abstract::Because nickel may have a biological function in a pathway in which vitamin B12 is important, an experiment was performed to determine the effects of nitrous oxide exposure in rats deprived of nickel. Exposure to nitrous oxide (N2O) causes inactivation of cobalamin and a subsequent decrease in the vitamin B12-dependen...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Uthus EO,Poellot RA

    更新日期:1993-07-01 00:00:00

  • Zinc Supplementation Increased Bone Mineral Density, Improves Bone Histomorphology, and Prevents Bone Loss in Diabetic Rat.

    abstract::Diabetic osteoporosis (DOP) is a complication of diabetes, with the characteristics of bone mineral density (BMD) reduction and bone structure destruction. Zinc was reported has a benefit effect on postmenopausal osteoporosise, it was also has hypoglycemic effect, whether zinc was beneficial on diabetes-induced osteop...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Qi S,He J,Zheng H,Chen C,Jiang H,Lan S

    更新日期:2020-04-01 00:00:00

  • Selenium and Iodine Levels in Subjects with Kashin-Beck Disease: a Meta-analysis.

    abstract::Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy, and particularly seen in China. A deficiency of selenium and iodine is implicated as the main etiological factor for KBD. This meta-analysis aimed to evaluate the differences in the selenium and iodine levels between patients with KBD and healthy ...

    journal_title:Biological trace element research

    pub_type: 杂志文章,meta分析


    authors: Yang L,Zhao GH,Yu FF,Zhang RQ,Guo X

    更新日期:2016-03-01 00:00:00

  • The acute and chronic effects of monosodium L-glutamate on serum iron and total iron-binding capacity in the jugular artery and vein of pigs.

    abstract::We analyzed the effects of acute and chronic oral administration of monosodium L-glutamate (MSG) on serum iron (Fe) levels and total iron-binding capacity (TIBC) in piglets. In the first experiment, 12 piglets were randomly assigned to two groups: one fed a standard diet (SD) and the other fed an SD containing MSG (10...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Xin W,Xugang S,Xie C,Li J,Hu J,Yin YL,Deng ZY

    更新日期:2013-06-01 00:00:00

  • An estimation of the manganese requirement for broilers from 1 to 21 days of age.

    abstract::A dose-response experiment was conducted to find the sensitive and consistent biomarker for the estimation of dietary manganese (Mn) requirement and establish the optimal Mn level for broilers fed a practical corn-soybean meal diet from 1 to 21 days of age post-hatching. A total of 480 1-day-old Arbor Acres male chick...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Li S,Lin Y,Lu L,Xi L,Wang Z,Hao S,Zhang L,Li K,Luo X

    更新日期:2011-11-01 00:00:00

  • Daily hyperhydration effect on electrolyte deficiency of endurance-trained subjects during prolonged hypokinesia.

    abstract::The aim of this study was to evaluate the effect of a daily intake of fluid and salt supplementation (FSS) on the deficiency of electrolytes, which is characterized by higher rather than lower plasma concentration of electrolytes during prolonged hypokinesia (HK) (decreased number of km taken per day). Forty long dist...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Zorbas YG,Yaroshenko YY,Kuznetsov NK,Matvedev SL

    更新日期:1998-07-01 00:00:00

  • Effect of Dietary Supplementation of Organic Trace Minerals at Reduced Concentrations on Performance, Bone Mineralization, and Antioxidant Variables in Broiler Chicken Reared in Two Different Seasons in a Tropical Region.

    abstract::Two experiments were conducted to study the performance, antioxidant activity, and bone mineral variables in broilers fed organic trace minerals (OTM) at lowered concentrations in the diet. In experiment 1, a total of 1500 day-old broiler male chicks were randomly distributed into six groups with 10 replicates of 25 c...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Savaram Venkata RR,Bhukya P,Raju MVLN,Ullengala R

    更新日期:2020-11-20 00:00:00

  • The influence of endodontic broken stainless steel instruments on the urinary levels of iron.

    abstract::Previous studies on the endodontic broken stainless steel instruments have mainly focused on retrieval of specimens. However, the systemic consequences of the retained separated instruments need an investigation. The current study aimed to evaluate the correlation between broken stainless steel instruments inside the ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Saghiri MA,Asatourian A,Haraji A,Ramezani GH,Garcia-Godoy F,Scarbecz M,Sheibani N

    更新日期:2014-06-01 00:00:00

  • Pulmonary deposition and clearance of a nickel oxide aerosol by inhalation.

    abstract::Wistar male rats were exposed to nickel oxide (NiO) aerosols (mass median aerodynamic diameter, 1.2 μm). The average exposure concentration was controlled from low level (0.6 mg/m(3)) to high level (8.0 mg/m(3)) and total exposure time ranged from 140 to 216 h. Some rats were sacrificed just after the exposure, wherea...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kodama Y,Ishimatsu S,Matsuno K,Tanaka I,Tsuchiya K

    更新日期:1985-02-01 00:00:00

  • Changes of zinc values in children during malignant disease.

    abstract::In 47 children with malignancy, zinc status, growth, and performance during standard treatment were compared with those in controls. At diagnosis, growth was retarded and hair zinc values were high, 2.4 +/- 0.7 mumol/g, as in chronic deficiency. During induction therapy, serum declined to 10.4 +/- 2.3 mumol/L and urin...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Van Wouwe JP,van Zuylen L

    更新日期:1991-09-01 00:00:00

  • Randomized Study of the Effects of Vitamin D and Magnesium Co-Supplementation on Muscle Strength and Function, Body Composition, and Inflammation in Vitamin D-Deficient Middle-Aged Women.

    abstract::This study aimed to investigate the effects of vitamin D and magnesium co-supplementation on muscle strength and function, body composition, and inflammation in vitamin D-deficient middle-aged women. In this study, 83 healthy middle-aged women (40-55 years) with vitamin D deficiency were randomly assigned into two gro...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kheyruri F,Sarrafzadeh J,Hosseini AF,Abiri B,Vafa M

    更新日期:2020-09-21 00:00:00