Abstract:
:The effects of nutritional copper deficiency on carrageenin edema in the rat were investigated with emphasis on studying the correlation between the degree of copper deficiency and the degree of edema. Carrageenin paw edema in both copper-sufficient and copper-deficient groups of rats was compared after either 20, 40, or 60 d on respective diets. The degree of copper deficiency was quantitated by analyzing total copper concentrations in a number of tissues. Other copper dependent parameters were also determined. Results indicated that: (1) although copper sufficient rats showed relatively little change in the degree of edema, copper-deficient rats showed a steady and significant increase in edema from d 20 to 40 to 60; (2) paw edema in copper-deficient animals was highly and negatively correlated to the concentrations of copper in the liver; the correlation with liver Cu,Zn-superoxide dismutase activity, however, was inconsistent; (3) paw edema was not correlated either to copper concentration in tissues other than liver or to plasma ceruloplasmin activity; and (4) aggravation of carrageenin edema in copper-deficient animals seemed to be mediated via an as yet unknown secondary effect of copper deficiency.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Kishore V,Wokocha B,Fourcade Ldoi
10.1007/BF02917181subject
Has Abstractpub_date
1989-01-01 00:00:00pages
97-107eissn
0163-4984issn
1559-0720journal_volume
23pub_type
杂志文章abstract::Zinc has been reported to enhance the response to interferon (IFN) or PEG-IFN plus ribavirin therapy, improve liver function, and ameliorate hematologic side effects in patients with chronic hepatitis C. However, the role of zinc supplementation during IFN therapy in chronic hepatitis B infection (CHB) remains unclear...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-8971-7
更新日期:2011-12-01 00:00:00
abstract::Heavy metals toxicity is a prevalent health problem particularly in developing countries. Mercury and cadmium are toxic elements that have no physiologic functions in human body. They should not be present in the human body by any concentration. Copper, on the other hand, is one of the elements that are essential for ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0525-y
更新日期:2016-06-01 00:00:00
abstract::The trace elements antimony, bromine, cesium, cobalt, iron, rubidium, scandium, strontium and zinc were determined by instrumental neutron activation analysis in breast tissue samples with fibrocystic disease and in samples with fibroadenoma tumors. The histological lesions of each breast sample with fibrocystic disea...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917337
更新日期:1994-10-01 00:00:00
abstract::The effect of increased selenium uptake on serum selenium in diabetic children was investigated during the first 9 yr of the Finnish nationwide selenium fertilization program, which started in 1984. Serum selenium concentrations were followed in 237 diabetic children (mean age 8.1 yr) and 214 controls from 1984 to 199...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790138
更新日期:1995-01-01 00:00:00
abstract::Extracellular Ca2+-influx induced by trivalent metal ions (Fe3+, Al3+, Cr3+, In3+, Ga3+, and La3+) in Ehrlich carcinoma cells is enhanced by ATP. This action seems to be related to the high coordination capacity of the ATP ligand that inhibits the polymerization of the solvated cations taking place at physiological pH...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02820027
更新日期:1998-04-01 00:00:00
abstract::Auditory brainstem electric response (ABR) and somatosensory evoked potential (SEP) of 21 subjects (41 ears) among villagers in a rare earth element (REE) area in Gan County, Jiangxi, China, were studied. No difference in ABR between the subjects from the REE area and the control group was noted. However, the conducti...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02803871
更新日期:1997-04-01 00:00:00
abstract::For this study, we investigate more deeply the effect calcium (Ca) develops on the mechanism underlying fluoride-triggered osteocyte apoptosis. We detected the morphology of osteocytes by HE staining, mitochondrial microstructure by using the transmission electron microscope, and the biochemical indexes related to bon...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02305-6
更新日期:2020-07-25 00:00:00
abstract::An external-sample liquid scintillation (LS) counting for the gamma emitter 75Se has been developed. An expressly designed well-type LS vial and a 2,5-diphenyoxazole-1,4-bis(5-phenyl-2-oxazoyl)-benzene-xylene solution containing 35% tertrabutylzinn allow 75Se to be counted in a standard LS counter with counting effici...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:77:3:287
更新日期:2000-12-01 00:00:00
abstract::The effect of zinc deficiency on calmodulin function was investigated by assessing the in vivo activity of two calmodulin regulated enzymes, adenosine 3',5'-monophosphate (c-AMP) and guanosine 3',5'-monophosphate (c-GMP) phosphodiesterase (PDE) in several rat tissues. Enzymatic activities in brain, heart, and testis o...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02797137
更新日期:1988-08-01 00:00:00
abstract::This study was performed to determine the effects of selenium supplementation on clinical symptoms and gene expression related to inflammatory markers in infertile women with polycystic ovary syndrome (PCOS) who were candidate for in vitro fertilization (IVF). Thirty-six women candidate for IVF were recruited in this ...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-019-01715-5
更新日期:2020-02-01 00:00:00
abstract::Exposure of people and animals to arsenic (As) is a global public health concern because As is widely distributed and associated with numerous adverse effects. As is a poisonous metalloid and arsenic trioxide (As2O3) is a form of As. Thus far, there have been very few reports on the inflammatory factor alterations of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0305-8
更新日期:2015-10-01 00:00:00
abstract::The study aimed at determination of the mineral composition of slimming herbal teas and estimation of the coverage of their total intake with infusions in women's daily diet. The content of Na+, K+, Ca+2, Mg+2, Zn+2, Cu+2, Fe+2, and Mn+2 was determined in infusions and mineralisates obtained from the slimming herbal t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0790-4
更新日期:2017-02-01 00:00:00
abstract::In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic) and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed that the formaldehyde inhalation caused gradual decline of body...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8686-1
更新日期:2011-05-01 00:00:00
abstract::Pituitary dwarfism (hGHD) is known to be associated with trace element deficiency, which causes improper functioning of the involved endocrine system. Previously, we reported on the head hair concentrations of zinc, copper, manganese, and iron from a total of 418 normal subjects (154 male and 264 female). In this repo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:85:2:127
更新日期:2002-02-01 00:00:00
abstract::A multitude of methods exists at present for the solubilization of biological tissues for atomic absorption analysis. We have examined several common methods of wet ashing using NBS bovine liver in order to determine which acids, acid combinations, or bases should be used as digesting agents for accurate and precise m...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990451
更新日期:1981-06-01 00:00:00
abstract::In vivo and in vitro studies were conducted to investigate the chemical forms by ion-exchange chromatography of selenium (Se) present in rat and ovine spermatozoa. After injection with 75Se-selenite, the form of 75Se in rat sperm was selenocysteine, but selenocysteine and selenomethionine (SeMet) were present in ovine...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:76:2:161
更新日期:2000-08-01 00:00:00
abstract::Mannheimia haemolytica is the main bacterial pathogen isolated in bovine respiratory disease (BRD), a common disease affecting calves before weaning. Previous research has shown that experimental infection with bovine herpesvirus 1, a respiratory virus, decreases plasma zinc (Zn) levels. However, changes in plasma Zn ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02145-4
更新日期:2021-01-01 00:00:00
abstract::We have previously shown that a low-copper (Cu) diet produced alterations in placental Cu transport and fetal Cu stores. Because Cu deficiency has been associated with lipid deposition in rat dam liver, we hypothesized that a high fat intake, a prevalent dietary habit in many populations, may worsen fetal Cu status an...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784069
更新日期:1999-02-01 00:00:00
abstract::Activity of the immunoregulatory peptide thymulin reflects differences in zinc status. This study compared thymulin activity with four other zinc status measures in rats fed zinc at either 5 or 25 ppm. Rats fed the lower zinc showed the following results compared with rats with adequate zinc intake: serum thymulin act...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02159-y
更新日期:2021-02-01 00:00:00
abstract::Multivariate statistical analysis has been applied to time series measurements of aerosol elemental composition from PIXE analysis of filter samples, and principal components have been resolved that represent distinct particle types in an external mixture in the atmosphere. In this study, it is argued that a combinati...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992673
更新日期:1990-07-01 00:00:00
abstract::Melipona quadrifasciata anthidioides is a species of stingless bee popularly known in Brazil as "mandaçaia". Products derived from bees for food and therapeutic uses, have stimulated the evaluation of the chemical composition of geopropolis. Concentrations of 24 essential and potentially toxic elements were determined...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02455-7
更新日期:2020-10-23 00:00:00
abstract::Forty-six elements have been detected in fresh banana pulp purchased weekly in Pittsburgh, PA for the past twelve years (1968-1980). Samples were prepared by lyophilization or low temperature ashing. Analyses were performed using X-ray fluorescence spectrometry, optical emission spectrometry, atomic absorption spectro...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789122
更新日期:1981-03-01 00:00:00
abstract::The effects of zinc chloride (ZnCl2), disodium zinc ethylenediamine tetraacetate (Zn-EDTA), and zinc gluconate (Zn-GLU) on the antioxidant enzyme activities and levels of interleukins (ILs) in psoriasis-induced mice were studied. One hundred twenty female mice were randomly divided into six groups with 20 mice in each...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9799-0
更新日期:2013-12-01 00:00:00
abstract::Quantitative analysis of follicular fluid and granulosa cells from small, medium and large antral atretic follicles of goat (Capra hircus) ovaries was conducted to study the alterations in trace elements viz zinc (Zn), copper (Cu), manganese (Mn), and iron (Fe). The zinc content was lower in the follicular fluid (0.99...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8700-7
更新日期:2011-06-01 00:00:00
abstract::Measurement and monitoring of magnesium (Mg) are important to prevent the development of serious and potentially fatal complications in critically ill patients. Although ion-selective electrodes are available and earlier reports suggest that free ionized magnesium (iMg2+) is the most useful test to estimate Mg status,...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:115:1:13
更新日期:2007-01-01 00:00:00
abstract::Magnesium (Mg) concentrations in diets have been associated with performance and eggshell quality of laying hens, but the results have been inconclusive. In this experiment, the effects of increasing concentrations of dietary Mg on productive performance and eggshell quality of aged laying hens were evaluated. A total...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9537-z
更新日期:2013-01-01 00:00:00
abstract::Fluoride can induce neurotoxicity, but the mechanism is not clear. In this study, we explored the role of autophagy in F--induced neurotoxicity of Wistar rats. Eighty Wistar rats were randomly divided into four groups: the control group (distilled water containing less than 0.1 mg/L F-) and three NaF-treated groups (F...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01735-1
更新日期:2020-02-01 00:00:00
abstract::Studies investigating the effects of Chromium (Cr) supplementation on unstressed broiler chickens have reported an inconsistent association between Cr supplementation and broiler chickens' responses. We conducted a dose-response meta-analysis of previous studies to assess the dose-response associations between Cr supp...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-021-02589-2
更新日期:2021-01-17 00:00:00
abstract::In three fully crossed, factorially arranged, completely randomized experiments, female weanling rats were fed a basal diet (containing about 10 ng of nickel and 2.3 μg of iron/g) supplemented with graded levels of nickel and iron. Iron was supplemented to the diet in experiment 1 at levels of 0, 25, 50, and 100 μg/g ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990121
更新日期:1981-09-01 00:00:00
abstract::This experiment was conducted to evaluate the effects of heme and non-heme iron sources on growth performances, blood parameters, tissue mineral concentration, and intestinal morphology in weanling pigs. At 25 days of age, 32 newly weaned piglets (Duroc × Landrace × Yorkshire; 8.66 ± 0.59 kg) were allocated to one of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1385-z
更新日期:2019-02-01 00:00:00