Heavy Metals Level, Health Risk Assessment Associated with Contamination of Black Tea; A Case Study from Khyber Pakhtunkhwa (KPK), Pakistan.

Abstract:

:In the present study, 15 different commercial tea brands sold in Khyber Pakhtunkhwa were collected from the markets. The samples were analyzed for the concentrations of ten selected heavy metals. The metal concentration showed a random distribution in all samples. The mean concentration of Cd, Cu, Mn, Pb, Zn, and Fe was found in the range of 0.029-0.094 mg kg-1, 7.11-12.30 mg kg-1, 20.73-24.17 mg kg-1, 0.159-0.824 mg kg-1, 1.136-2.938 mg kg-1, and 0.670-118.30 mg kg-1 respectively. Co, Cr, Ni, and Sb were found below the detection limit of the instrument. Cu and Mn were found to be the abundant metals with a high concentration in the collected samples. The estimated daily intake (EDI), target hazard quotients (THQs), and hazard index (HI) were used for the assessment of health risks associated with the intake of metals. The metal transfer rates to tea infusion were reported from previous studies. Except for Cu, the EDI values of all the elements were found to be lower than the RfD values. The corresponding HI values of metals, in the different tea brands, were found to be below 1 suggesting that the consumption of mature tea infusions in the studied area could cause no carcinogenic risk. The principle cluster analysis (PCA) was used to reduce the number of variables to a new set which extracted three factors. For the assessment of health risks associated with dietary metal exposure, constant determination of heavy metals in all food is necessary. The present study provides valuable information to the general public about the consumption of tea infusions.

journal_name

Biol Trace Elem Res

authors

Idrees M,Jan FA,Hussain S,Salam A

doi

10.1007/s12011-020-02059-1

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

344-349

issue

1

eissn

0163-4984

issn

1559-0720

pii

10.1007/s12011-020-02059-1

journal_volume

198

pub_type

杂志文章
  • Antibacterial, Antifungal and Nematicidal Activities of Rare Earth Ions.

    abstract::Despite the name, rare earth elements are relatively abundant in soil. Therefore, these elements might interact with biosphere during the history of life. In this study, we have examined the effect of rare earth ions on the growth of bacteria, fungi and soil nematode. All rare earth ions, except radioactive promethium...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0727-y

    authors: Wakabayashi T,Ymamoto A,Kazaana A,Nakano Y,Nojiri Y,Kashiwazaki M

    更新日期:2016-12-01 00:00:00

  • Effect of calcium, tannic acid, phytic acid and pectin over iron uptake in an in vitro Caco-2 cell model.

    abstract::Calcium, phytic acid, polyphenols and fiber are major inhibitors of iron absorption and they could be found in excess in some diets, thereby altering or modifying the iron nutrition status. The purpose of this study is to evaluate the effect of calcium, tannic acid, phytic acid, and pectin over iron uptake, using an i...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-9911-0

    authors: Andrews M,Briones L,Jaramillo A,Pizarro F,Arredondo M

    更新日期:2014-04-01 00:00:00

  • The ratio of sTfR/ferritin is associated with the expression level of TfR in rat bone marrow cells after endurance exercise.

    abstract::Currently, it is unclear which index of haematological parameters could be used to most easily monitor iron deficiency during endurance training. To address this question, 16 male Wistar rats were randomly assigned to two groups: a sedentary group (n = 8) and an exercised group (n = 8). Initially, animals in the exerc...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9312-6

    authors: Tian Y,Zhao J,Zhao B,Gao Q,Xu J,Liu D

    更新日期:2012-06-01 00:00:00

  • Effect of some nickel compounds on red blood cell characteristics.

    abstract::The effect of certain inorganic and coordinated nickel compounds on the resistance to different destructive substances, rheological properties, and functional activity of healthy human red blood cells (RBC), was investigated. It is shown that nickel compounds affect the erythrocyte membrane lipid bilayer, as well as m...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02917273

    authors: Tkeshelashvili LK,Tsakadze KJ,Khulusauri OV

    更新日期:1989-07-01 00:00:00

  • Impaired peripheral zinc metabolism in patients with senile dementia of probable Alzheimer's type as shown by low plasma concentrations of thymulin.

    abstract::Plasma concentrations of a zinc carrier peptide, namely thymulin, were measured according to a bioassay in young donors, healthy elderly, and patients with senile dementia of Alzheimer's type (SDAT). Thymulin is a hormone released by thymic epithelial cells and its biological activity on cells of immune system is depe...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02790147

    authors: Licastro F,Davis LJ,Mocchegiani E,Fabris N

    更新日期:1996-01-01 00:00:00

  • Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study.

    abstract::The toxicological literature is replete with studies attempting to explain the mechanism of action of organophosphorus (OP) insecticides to their anticholinesterase activities, but not much is known about the metabolism and detoxification of these compounds. The goal of this study was to ascertain the toxic effects of...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:74:2:171

    authors: Goel A,Chauhan DP,Dhawan DK

    更新日期:2000-05-01 00:00:00

  • Selenium-dependent glutathione peroxidase modules encoded by RNA viruses.

    abstract::Glutathione peroxidase (GPx) is the prototypical eukaryotic selenoprotein, with the rare amino acid selenocysteine (Sec) at the enzyme active site, encoded by the UGA codon in RNA. A DNA virus, Molluscum contagiosum, has now been shown to encode a functional selenium-dependent GPx enzyme. Using modifications of conven...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783852

    authors: Zhang W,Ramanathan CS,Nadimpalli RG,Bhat AA,Cox AG,Taylor EW

    更新日期:1999-11-01 00:00:00

  • Oxidative stress induced by cadmium in the C6 cell line: role of copper and zinc.

    abstract::In this report, we have investigated the role of copper (Cu) and zinc (Zn) in oxidative stress induced by cadmium (Cd) in C6 cells. Cells were exposed to 20 μM Cd, 500 μM Cu, and 450 μM Zn for 24 h. Then, toxic effects, cellular metals levels, oxidative stress parameters, cell death, as well as DNA damage were evaluat...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9265-9

    authors: Nzengue Y,Steiman R,Rachidi W,Favier A,Guiraud P

    更新日期:2012-06-01 00:00:00

  • The effects of magnesium deficiency on molybdenum metabolism in rats.

    abstract::Our previous report indicated that magnesium (Mg) deficiency increased molybdenum (Mo) concentration in the rat liver, suggesting the possibility that Mg deficiency affects Mo metabolism. Growing male rats were given a control diet or a Mg-deficient diet for 4 weeks. Urine and feces were collected during the second an...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9541-3

    authors: Kim KH,Funaba M,Yoshida M,Matsui T

    更新日期:2013-01-01 00:00:00

  • Developmental Neurotoxicity of Arsenic: Involvement of Oxidative Stress and Mitochondrial Functions.

    abstract::Over the last decade, there has been an increased concern about the health risks from exposure to arsenic at low doses, because of their neurotoxic effects on the developing brain. The exact mechanism underlying arsenic-induced neurotoxicity during sensitive periods of brain development remains unclear, although enhan...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1286-1

    authors: Chandravanshi LP,Gupta R,Shukla RK

    更新日期:2018-11-01 00:00:00

  • Retraction note to: The effect of lead acetate toxicity on experimental male albino rat.

    abstract::Retraction to: Biol Trace Elem Res 144(1–3):1120–1132, DOI 10.1007/s12011-011-9149-z. Article has been retracted due to duplicate publication. ...

    journal_title:Biological trace element research

    pub_type: 撤回出版物

    doi:10.1007/s12011-012-9550-2

    authors: Ibrahim NM,Eweis EA,El-Beltagi HS,Abdel-Mobdy YE

    更新日期:2013-01-01 00:00:00

  • Serum selenium versus lymphocyte subsets and markers of disease progression and inflammatory response in human immunodeficiency virus-1 infection.

    abstract::Serum selenium levels were determined cross-sectionally in 57 HIV-infected patients who were classified according to the Centers for Disease Control (CDC) 1993 classification system. Mean serum selenium levels were lower in CDC stage II (58.7 +/- 12.2 micrograms/L; p < 0.01; n = 18) and stage III (47.6 +/- 11.3 microg...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02778982

    authors: Look MP,Rockstroh JK,Rao GS,Kreuzer KA,Spengler U,Sauerbruch T

    更新日期:1997-01-01 00:00:00

  • Effects of increasing supplementation of magnesium in diets on productive performance and eggshell quality of aged laying hens.

    abstract::Magnesium (Mg) concentrations in diets have been associated with performance and eggshell quality of laying hens, but the results have been inconclusive. In this experiment, the effects of increasing concentrations of dietary Mg on productive performance and eggshell quality of aged laying hens were evaluated. A total...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9537-z

    authors: Kim CH,Paik IK,Kil DY

    更新日期:2013-01-01 00:00:00

  • Impact of boron deficiency on Xenopus laevis: a summary of biological effects and potential biochemical roles.

    abstract::The toxicity of boron has been understood for many years. However, limited data currently exist concerning the nutritional essentiality of B in chordates. Results from an ongoing research program evaluating the nutritional essentiality of B in the South African clawed frog, Xenopus laevis, found that X. laevis fed a l...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1385/BTER:90:1-3:117

    authors: Fort DJ,Rogers RL,McLaughlin DW,Sellers CM,Schlekat CL

    更新日期:2002-01-01 00:00:00

  • Age-related changes in the concentrations of major and trace elements in the brain of rats and mice.

    abstract::Age-related changes in the concentrations of constituent elements in the brains of rats and mice 1 wk to 24 mo old were determined with inductively coupled plasma-mass spectrometry (ICP-MS) and inductively coupled plasma-atomic emission spectrometry (ICP-AES). Seventeen elements could be determined with reasonable acc...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:80:2:145

    authors: Takahashi S,Takahashi I,Sato H,Kubota Y,Yoshida S,Muramatsu Y

    更新日期:2001-05-01 00:00:00

  • Associations Between Copper and Zinc and Risk of Hypertension in US Adults.

    abstract::Evidence linking copper and zinc to hypertension are limited and conflicting. Data from the National Health and Nutrition Examination Survey (NHANES) 2007-2014 were used. Zinc and copper intake from diet and supplements was assessed with 24-h dietary recall. Hypertension was defined as systolic blood pressure (SBP) ≥ ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1320-3

    authors: Yao J,Hu P,Zhang D

    更新日期:2018-12-01 00:00:00

  • Resveratrol Attenuates Copper and Zinc Homeostasis and Ameliorates Oxidative Stress in Type 2 Diabetic Rats.

    abstract::Diabetes is a common metabolic disorder characterized by elevated blood glucose level. Trace element homeostasis causes disturbances in diabetes due to hyperglycemia. Superoxide dismutase (SOD), an antioxidant enzyme, contains zinc and copper ions as its cofactors. Defects in SOD level and activity have been observed ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0861-6

    authors: Asadi S,Moradi MN,Khyripour N,Goodarzi MT,Mahmoodi M

    更新日期:2017-05-01 00:00:00

  • Comparison of selenium levels in pre-eclamptic and normal pregnancies.

    abstract::Abnormal placentation is the likely cause of the slow fetal growth and the high levels of circulating lipid peroxides found in severe pre-eclampsia. These peroxides are probably responsible for the high thromboxane:prostacyclin ratio found in this disease and may participate in the endothelial cell damage which is its...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02784164

    authors: Rayman MP,Abou-Shakra FR,Ward NI,Redman CW

    更新日期:1996-10-01 00:00:00

  • Ensemble modeling coupled with six element concentrations in human blood for cancer diagnosis.

    abstract::Six important metal contents (i.e., zinc, barium, magnesium, calcium, copper, and selenium) in blood samples coupled with an ensemble classification algorithm have been used for the classification of normal people and cancer patients. A dataset containing 42 healthy samples and 32 cancer samples was used for experimen...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8864-1

    authors: Chen H,Tan C,Wu T

    更新日期:2011-10-01 00:00:00

  • Are Heavy Metal Exposure and Trace Element Levels Related to Metabolic and Endocrine Problems in Polycystic Ovary Syndrome?

    abstract::This study aimed to determine the relationship between the metabolic and endocrinological pathologies in polycystic ovary syndrome (PCOS) and the levels of arsenic, chromium, cadmium, lead, mercury, antimony, zinc, and copper to evaluate the relationship of these toxic metals with inflammatory/oxidative parameters. Th...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02220-w

    authors: Kirmizi DA,Baser E,Turksoy VA,Kara M,Yalvac ES,Gocmen AY

    更新日期:2020-11-01 00:00:00

  • Natural variation in grain selenium concentration of wild barley, Hordeum spontaneum, populations from Israel.

    abstract::Wild barley (Hordeum spontaneum), the progenitor of cultivated barley, is an important genetic resource for cereal improvement. Selenium (Se) is an essential trace mineral for humans and animals with antioxidant, anticancer, antiarthropathy, and antiviral effects. In the current study, the grain Se concentration (GSeC...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8770-6

    authors: Yan J,Wang F,Qin H,Chen G,Eviatar N,Fahima T,Cheng J

    更新日期:2011-09-01 00:00:00

  • Protection from H1N1 influenza virus infections in mice by supplementation with selenium: a comparison with selenium-deficient mice.

    abstract::The present paper describes protective effects of supplemental selenium in mice infected with influenza virus. The effects of supplemental selenium on serum selenium levels, mortality, lung virus titers, and cytokine titers were investigated in mice inoculated intranasally with suspensions of influenza virus. Whereas ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8726-x

    authors: Yu L,Sun L,Nan Y,Zhu LY

    更新日期:2011-06-01 00:00:00

  • Possible correlation between selenoprotein W and myogenic regulatory factors in chicken embryonic myoblasts.

    abstract::The biological function of selenium (Se) is mainly elicited through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, is essential for the normal function of the skeletal muscle system. To investigate the possible relationship of Se in the process of differentiation in chicken myo...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9520-8

    authors: Wu Q,Yao HD,Zhang ZW,Zhang B,Meng FY,Xu SW,Wang XL

    更新日期:2012-12-01 00:00:00

  • Short-term effects of sibutramine on mineral status and selected biochemical parameters in obese women.

    abstract::The aim of this study was to assess the effect of sibutramine on mineral status and selected biochemical parameters in obese women. The study was conducted on 24 patients who received 15 mg daily doses of sibutramine for 12 weeks, and on 20 patients who received placebo. At the baseline, after the sixth and twelfth we...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-012-9425-6

    authors: Suliburska J,Bogdański P,Szulińska M,Pupek-Musialik D

    更新日期:2012-11-01 00:00:00

  • Lactobacillus plantarum CCFM639 Alleviate Trace Element Imbalance-Related Oxidative Stress in Liver and Kidney of Chronic Aluminum Exposure Mice.

    abstract::Aluminum (Al) has various adverse effects on health of humans and animals. The aim of present study was to demonstrate that Lactobacillus plantarum CCFM639 can alleviate the adverse effects on liver and kidney of mice caused by chronic Al exposure. Animals were assigned into control, CCFM639 only, Al only, Al plus CCF...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0843-8

    authors: Yu L,Zhai Q,Yin R,Li P,Tian F,Liu X,Zhao J,Gong J,Zhang H,Chen W

    更新日期:2017-04-01 00:00:00

  • Nuclear microscopy in the life sciences at the National University of Singapore. A review.

    abstract::The nuclear microscope is now gaining popularity in the field of life sciences. In particular, the combination of proton-induced X-ray emission to measure the elemental concentrations of inorganic elements, Rutherford backscattering spectrometry to characterize the organic matrix, and scanning transmission ion microsc...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/BF02784192

    authors: Ren MQ,Thong PS,Makjanic J,Ponraj D,Watt F

    更新日期:1999-01-01 00:00:00

  • Determining human dietary requirements for boron.

    abstract::A dietary requirement is defined as the lowest continuing intake of a nutrient that for a specified indicator of adequacy, will maintain a defined level of nutriture in an individual. An essential dietary component is one that the body cannot synthesize in sufficient quantities to maintain health. Recommended dietary ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783138

    authors: Sutherland B,Strong P,King JC

    更新日期:1998-01-01 00:00:00

  • The influence of fluoride ions upon selected enzymes of protein metabolism in blood plasma of rabbits with hypercholesterolemia.

    abstract::Three-month studies were performed on 18 adult rabbits of New Zealand breed divided into three groups, with six animals in each: a control group on standard diet, a cholesterol group receiving 500 mg of cholesterol/100 g of feed per rabbit per 24 h (CH group), and a cholesterol + fluorine group (CH + F group) receivin...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-008-8129-4

    authors: Birkner E,Grucka-Mamczar E,Kasperczyk S,Kasperczyk A,Stawiarska-Pieta B,Zalejska-Fiolka J,Birkner B

    更新日期:2008-08-01 00:00:00

  • Cerium Oxide Nanoparticles Attenuate Oxidative Stress and Inflammation in the Liver of Diethylnitrosamine-Treated Mice.

    abstract::The catalytic activity of cerium oxide nanoparticles (CeO2NPs) is responsible for its application as an antitumor agent. This activity may be due to its ability to switch between III and IV oxidation states thereby conferring pro- and antioxidant properties. This study was designed to assess the hepatoprotective poten...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01696-5

    authors: Adebayo OA,Akinloye O,Adaramoye OA

    更新日期:2020-01-01 00:00:00

  • The Determination of Toxic Metals in some Traditional Cosmetic Products and Health Risk Assessment.

    abstract::In present study, the levels of some toxic elements in 19 different home-made cosmetic products (spray hair dye, henna, tattoo, eyeliner, eye mascara, smear, lip moisturizer, and lipstick) were analyzed by inductively coupled plasma mass spectrometric (ICP-MS) after microwave digestion. The ICP-MS results were verifie...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02357-8

    authors: Kilic S,Kilic M,Soylak M

    更新日期:2020-09-05 00:00:00