Abstract:
:The effects of cobaltous chloride in inducing chromosomal aberrations were observed on laboratory bred mice in vivo after single oral administration of different fractions (1/10, 1/20, 1/40) of the lethal toxic dose of the salt. Bone marrow cells were flushed out and processed for chromosome studies following colchicine, hypotonic, giemsa, air drying procedure. The parameters screened were chromosomal aberrations, with and without gaps and break per cell. Slides were screened after the expiry of 6, 12, 18, and 24 h. Statistical analysis indicated the clastogenic effects of the salt. The degree of chromosome damage was directly related to the concentration, and also to the period after administration. The different stages of the cell cycle were affected.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Palit S,Sharma A,Talukder Gdoi
10.1007/BF03032691subject
Has Abstractpub_date
1991-05-01 00:00:00pages
139-45issue
2eissn
0163-4984issn
1559-0720journal_volume
29pub_type
杂志文章abstract::Conflicting results exist between selenium concentration and preeclampsia. The role of selenium in the development of preeclampsia is unclear. We conducted a meta-analysis to compare the blood selenium level in patients with preeclampsia and healthy pregnant women, and to determine the effectiveness of selenium supple...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s12011-015-0545-7
更新日期:2016-06-01 00:00:00
abstract::Gender differences are related to the manner in which the heart responds to chronic and acute stress conditions of physiological and pathological nature. Depending on dose, sodium selenite acts as an antioxidant proven to have beneficial effects in several pathological conditions G. Drasch, J. Schopfer, and G. N. Schr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02698014
更新日期:2007-06-01 00:00:00
abstract::Exposure of people and animals to arsenic (As) is a global public health concern because As is widely distributed and associated with numerous adverse effects. As is a poisonous metalloid and arsenic trioxide (As2O3) is a form of As. Thus far, there have been very few reports on the inflammatory factor alterations of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0305-8
更新日期:2015-10-01 00:00:00
abstract::Attempts were made to promote germination of natural aged rice seeds by treating them with lanthanum nitrate. In tests to measure the germination rate, germination index, and vigor index of natural aged rice seeds were found to be significantly increased by lanthanum. It is treating aged rice seed with lanthanum nitra...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:75:1-3:205
更新日期:2000-07-01 00:00:00
abstract::The role of zinc (Zn) in hepatic steatosis of patients with HCV-related chronic liver disease (CLD-C) remains uncertain, although persistent HCV infection often evokes hepatic steatosis. The primary purpose of this study was to elucidate the contribution of Zn deficiency to hepatic steatosis in patients with CLD-C. Fi...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-014-0177-3
更新日期:2015-02-01 00:00:00
abstract::Although recent studies have shown that chromium (as the trivalent ion) is not an essential trace element, it has been demonstrated to generate beneficial effects at pharmacologically relevant doses on insulin sensitivity and cholesterol levels of rodent models of insulin insensitivity, including models of type 2 diab...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/s12011-015-0231-9
更新日期:2015-07-01 00:00:00
abstract::Zinc deficiency, which is common among Iranian populations, is believed to play a crucial role in the onset and progression of mood disorders such as depression in different stages of life. We have therefore investigated the relationship between serum/dietary zinc status and depression scores among adolescent girls li...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-018-1301-6
更新日期:2018-11-01 00:00:00
abstract::This study was designed to investigate the pro-inflammatory cytokines and their involvement in the cytotoxic potential of fluoride (F) in HeLa cells. HeLa cells were cultured with varying F concentrations (1-50 mg/L) for 48 h, and treatment effects were analyzed. The viability of HeLa cells was determined with a color...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0749-5
更新日期:2017-01-01 00:00:00
abstract::Metal nanoparticles synthesized by green methods with the use of microorganisms are currently one of the most closely studied types of nanomaterials. It has accurately been shown that the characteristics of metal nanoparticles generated in the presence of different bacteria vary. For the two isogenic strains of obliga...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01740-4
更新日期:2020-02-01 00:00:00
abstract::The metabolism of 203Hg-labeled methylmercury chloride (MeHg) has been studied in rabbits and hamsters. Rabbits were administered 1.6 mumols MeHgCl/kg bw intravenously, and hamsters 40 mumols/kg bw orally. Urine and feces were collected daily and groups of four animals killed after 1 h, 1 d, or 7 d. The concentration ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917256
更新日期:1989-07-01 00:00:00
abstract::The abnormal metabolism of metal ions plays an important role in health and disease conditions; hence, the studies about them have received much interest. The objective of this study was to evaluate the association between trace and toxic elements zinc (Zn), cadmium (Cd), selenium (Se), and mercury (Hg) in biological ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0048-y
更新日期:2014-08-01 00:00:00
abstract::The aim of this study was to analyze the effect of high dietary Fe on liver antioxidant status in mice fed a corn-oil-enriched diet. Male Balb/c mice were fed for 3 wk with a standard diet enriched with 5% by weight of corn oil with adequate Fe (FCO diet) or supplemented with 1% carbonyl Fe (FCOFe diet). The control g...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:113:2:177
更新日期:2006-11-01 00:00:00
abstract::Since waterborne minerals appear in ionic form and are readily absorbed by the gastrointestinal tract, drinking water could be a crucial source of mineral intake. However, no comprehensive research has yet determined how trace elements in drinking water relate to body composition. We aimed to assess the relationship b...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-016-0779-z
更新日期:2017-02-01 00:00:00
abstract::The solubility of both free and low molecular weight ligand complexed calcium, magnesium, and zinc in skimmed human and bovine milks over intestinal luminal pH ranges (approximately 3-7) was measured using ultrafiltration techniques. Some of the experimental difficulties associated with the separation of labile metal ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02925450
更新日期:1989-01-01 00:00:00
abstract::Samples of Evernia prunastri, collected in a mountainous zone, were exposed in urban and highly industrialized areas in order to monitor the atmospheric pollution. Amounts of Cr, Mn, Fe, Ni, Cu, Zn, and Pb were determined by EDXRF spectrometry in secondary target excitation mode and in the thin film approach. An incre...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917318
更新日期:1994-10-01 00:00:00
abstract::Previous studies revealed that Se was an important regulatory factor for glutathione peroxidase (GPx) genes. However, the relationship between Se concentrations and mRNA expression levels of GPxs were unclear in goats, especially the goats living in natural Se-enriched area. Thus, the aim of this study was to determin...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9830-5
更新日期:2013-12-01 00:00:00
abstract::Manganese (Mn) is an essential nutrient for both host and pathogen. Recent studies have demonstrated the nutritional immunity of Mn against Salmonella infection in mammals. To investigate the effect of high dietary Mn on immune responses of broilers following Salmonella challenge, 144 1-day-old male broilers were fed ...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-017-1060-9
更新日期:2018-02-01 00:00:00
abstract::Given the conflicting results about the positive effects of magnesium and L-carnitine and as there is no report concerning concurrent supplementation of magnesium and L-carnitine on migraine prophylaxis, the effects of magnesium, L-carnitine, and concurrent magnesium-L-carnitine supplementation on migraine indicators ...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-012-9487-5
更新日期:2012-12-01 00:00:00
abstract::Adaptive alterations in glutathione (GSH) metabolism were studied during oxidative stress induced by selenium (Se) deficiency in germinating seedlings of Trigonella foenum-graecum grown for 72 h and the response to supplementation individually of Se or mimosine was explored. Growth enhancement with improved mitochondr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783830
更新日期:1999-12-01 00:00:00
abstract::The tissue distribution of 14 elements was simultaneously determined in rats 28 d after hypophysectomy (HPY), thyroparathyroidectomy (TPTY), adrenalectomy (ADY), and castration (CTN). The elements Na, K, Ca, Mg, Fe, S, P, Rb, Sr, Mn, Cu, and Zn were investigated in whole blood, plasma, brain, liver, kidney, heart, ske...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02797096
更新日期:1988-07-01 00:00:00
abstract::Concentrations of major nutritional and trace elements (Ca, P, Mg, Na, K, Fe, Zn, Cu, Mn, Se, Co, Cr, Ni, Sr, and Ba), as well as toxic heavy metals (Cd and Pb), were analyzed in the longissimus muscle of Charolais, Hereford, and Simmental bulls. The elements were determined using inductively coupled plasma optical em...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9913-y
更新日期:2014-04-01 00:00:00
abstract::AFB1 is a mycotoxin which exerts their cytotoxicity through increasing oxidative damage in target organ. Kidney is one of target organs vulnerable to damage caused by AFB1. In this study, Madin-Darby canine kidney (MDCK) cells were used to evaluate the AFB1-induced cell damage by the MTT assay. The results revealed th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9887-9
更新日期:2014-03-01 00:00:00
abstract::During pregnancy, the demand for daily iodine increases by 50-70% which occurs to reach around 250 μg/day. Limited information is available on the association of high-risk pregnancy (HRP) with urinary iodine concentration (UIC) and variables such as socioeconomic factors. To analyze iodine nutritional status and socio...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02028-8
更新日期:2020-10-01 00:00:00
abstract::The effect of aging on the status of macrominerals and trace elements in tissues was studied using two strains (SAMP1 and SAMR1) of senescence accelerated mouse. Two-month-old, 6-mo-old, and 10-mo-old female SAMP1 and SAMR1 mice were fed a commercial diet. Iron, zinc, copper, calcium, magnesium, phosphorus, sulfur, so...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:1:53
更新日期:2001-04-01 00:00:00
abstract::In this study, a new method was developed for the pre-concentration of trace mercury from seafood samples prior to analysis by spectrophotometry. The method is based on the complexation between 2-hydrazinobenzothiazole (2-HBT)-modified copolymer(s) and Hg(II) in the presence of an ionic surfactant, cetyltrimethylammon...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1614-5
更新日期:2019-09-01 00:00:00
abstract::The molecular localization of maternal and fetal zinc and copper metalloproteins in diabetic and control rats was studied. Compared to controls, liver and kidneys of diabetic dams showed an increased concentration of zinc and copper that was associated with metallothionein. In contrast, fetuses of diabetic dams had lo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917490
更新日期:1988-12-01 00:00:00
abstract::Deficiency of intracellular magnesium (icMg) may coexist with normal serum Mg levels. Little is known about clinical and pharmacological factors affecting icMg in normomagnesemic patients with diabetes mellitus (DM). Moreover, no information exists regarding the icMg state in diabetic patients after acute illness and ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-8024-4
更新日期:2007-01-01 00:00:00
abstract::In the mouse embryo cell line BALB/3T3 Clone A31-1-1, dose-dependent morphologic neoplastic transformation was obtained with NaAsO2, Na2HAsO4, CdCl2, and K2CrO4. Cellular uptake was four fold higher for As3+ than for As5+, and As5- was metabolized to As3+ in cytosol. Cytotoxicity and transformation rates were four fol...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917291
更新日期:1989-07-01 00:00:00
abstract::The relaxation rates (1/T(1) and 1/T(2)) in cysts have already been analyzed in terms of materials such as albumin, cholesterol, manganese, iron, and copper. However, the relaxivities of these materials have not been determined yet. In this work, five sets containing the ions, albumin, and cholesterol were prepared by...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8170-3
更新日期:2008-12-01 00:00:00
abstract::Plasma concentrations of a zinc carrier peptide, namely thymulin, were measured according to a bioassay in young donors, healthy elderly, and patients with senile dementia of Alzheimer's type (SDAT). Thymulin is a hormone released by thymic epithelial cells and its biological activity on cells of immune system is depe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790147
更新日期:1996-01-01 00:00:00