Abstract:
:The tissue distribution of 14 elements was simultaneously determined in rats 28 d after hypophysectomy (HPY), thyroparathyroidectomy (TPTY), adrenalectomy (ADY), and castration (CTN). The elements Na, K, Ca, Mg, Fe, S, P, Rb, Sr, Mn, Cu, and Zn were investigated in whole blood, plasma, brain, liver, kidney, heart, skeletal muscle, and bone. Additionally Mo was determined in kidney and liver. The following results were obtained: 1) With regard to hormone deficiency: HPY induced the most noticeable variations on all the elements tested owing probably to the direct and indirect effects of adenohypophyseal hormones. ADY led to the expected modification of Na and K but also to a Sr accumulation and a Rb depletion. TPTY induced a sharp decrease in plasma and tissues Ca, an increase in plasma P, but did not disturb the two elements in bone. An increase of Rb in many tissues and of Fe in heart, kidney, and liver were also observed. CTN had little consequences except in bone whose Cu and Fe contents were increased; 2) With regard to element variations: K, Mg, and S underwent little change. Discriminations were revealed between elements such as K and Rb, Ca and Sr, Ca and Mg, and Cu and Zn. The changes of Rb and Sr were consistent with regulatory mechanisms. The accumulation of Fe and Cu in tissues such as liver after HPY, TPTY, and ADY, suggest that the hormonal deficiencies could worsen the hemochromatosis and Wilson's disease; 3) With regard to plasma and tissues: No correlation appeared in element levels between plasma and other tissues. Brain was the least affected and liver, kidney and bone the most.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
LeBlondel G,Ducouret C,Allain Pdoi
10.1007/BF02797096subject
Has Abstractpub_date
1988-07-01 00:00:00pages
115-27issue
2eissn
0163-4984issn
1559-0720journal_volume
16pub_type
杂志文章abstract::We investigated the possible correlation between the leptin concentration and the Zn/Cu ratio in the plasma of women with thyroid disorder. Forty women with hypothyroidism (n = 20) or hypothyroidism (n = 20) and 20 euthyroid controls were recruited. The results showed that the women with thyroid disorder (hypothyroidi...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/BTER:75:1-3:99
更新日期:2000-07-01 00:00:00
abstract::Concentrations of toxic elements (lead, cadmium, mercury, and arsenic) were measured in water, sediment, and four commercial fish species (Cyprinus carpio, Hypophthalmichthys molitrix, Silurus glanis, and Esox lucius) and their tissues (muscle, liver, and kidney) from Saničani Lake, Bosnia and Herzegovina. The concent...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01982-2
更新日期:2020-09-01 00:00:00
abstract:CONTEXT:Complementary alternative medicine therapies based on the use of cesium chloride preparations for the treatment of cancer and radiation poisoning, have generated therapeutic interest; but oral or intravenous administration of cesium chloride (CsCl) to cancer patients as an alternative mode of cancer therapy hav...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:94:2:97
更新日期:2003-08-01 00:00:00
abstract::Scleroderma, sclerosis of the skin, is a severe autoimmune disease refractant to all kind of treatments. To study the in vivo effects of a combination of three oligoelements selenium (Se), zinc (Zn), and manganese (Mn) plus Lachesis muta venom (O-LM) on the bleomycin (BLM)-induced scleroderma mouse experimental model....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9876-4
更新日期:2014-02-01 00:00:00
abstract::Assessment of trace element levels in general population from the specific area is of importance for nutritional and occupational monitoring. In the current study, baseline blood levels of 12 toxic and/or essential metals and metalloids, including arsenic (As), cadmium (Cd), lead (Pb), mercury (Hg), chromium (Cr), tha...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1486-8
更新日期:2019-06-01 00:00:00
abstract::The aim of this study was to explore the effects of selenium addition on hepatic tissue ultrastructure and mitochondrial antioxidant capacity in copper-overloaded rats. Eighteen adult male Sprague-Dawley (SD) rats were randomly divided into three groups (n = 6 per group). Each group received 1 mL (intragastrically) of...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0293-8
更新日期:2015-09-01 00:00:00
abstract::Tibetan sheep have been observed with mineral deficiencies and marginal deficiencies in Qinghai-Tibetan Plateau. Adequate amounts of essential minerals are critical to maximize the productivity and health of livestock. The objectives of this study were to evaluate the effects of 6 months of mineral block supplementati...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-015-0593-z
更新日期:2016-08-01 00:00:00
abstract::Indigenous preparations (IPs) have evoked a considerable interest in alleviating infections and chronic diseases and improving wellbeing. While such formulations have been a part of traditional practice in several countries and many have been reviewed scientifically for their claims, several of them until date remain ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1411-1
更新日期:2019-04-01 00:00:00
abstract::The relationship between Ni-induced hepatic lipid peroxidation (LPO) and the concentrations of Ni and trace elements was investigated in male ICR mice. The protective effects of antioxidants were also examined. Hepatic LPO and the concentrations of Ni, Fe, Cu, and Zn in the liver were enhanced after an ip injection of...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784030
更新日期:1998-02-01 00:00:00
abstract::Neutron activation analysis (NAA) methodology was applied for the certification of eight trace elements (As, Co, Cr, Cu, Hg, Mn, Se, and Zn) in a plankton reference material (CRM 414) prepared by the BCR of the Commission of the European Communities. Average concentrations (micrograms/g dry wt) and standard deviations...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917365
更新日期:1994-10-01 00:00:00
abstract::Naphthalene-1-acetic acid (HNAA), dichlorophenoxy acetic acid (HDAA), and indole-3-acetic acid (HIAA) are auxinhormones that can affect the growth of plants. The lanthanide complexes of the above auxinhormone LnA3 x 3H2O (Ln = La3+, Ce3+, Sm3+, Er3+, Yb3+; HA = HNAA, HDAA, HIAA; A = NAA-, DAA-, IAA-) were synthesized ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783322
更新日期:1998-07-01 00:00:00
abstract::Iron and copper are essential microminerals that are intimately related. The present study was performed to determine the effect of iron-deficiency anemia (IDA) and treatment with iron on laboratory indicators of copper status. Hemoglobin, mean corpuscular volume erythrocyte Zn protoporphyrin, serum ferritin, serum co...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:112:3:213
更新日期:2006-09-01 00:00:00
abstract::This review discusses the development of studies that evaluated the essentiality and requirements of iron from the ancient to the present. The therapeutic effects of iron compounds were recognized by the ancient Greeks and Romans. The earliest recognition of the essentiality of iron was stated by Paracelsus, a disting...
journal_title:Biological trace element research
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s12011-018-1584-7
更新日期:2019-03-01 00:00:00
abstract::The objective of this study was to determine whether different dietary vitamin E (VE) and selenium (Se) levels affect the nutrient digestibility, production performance, and antioxidant abilities of growing furring blue foxes. A 4 × 2 factorial arrangement that included 4 levels of VE (0, 100, 200, or 400 mg/kg diet f...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-1655-4
更新日期:2019-12-01 00:00:00
abstract::Age-related changes in the concentrations of constituent elements in the brains of rats and mice 1 wk to 24 mo old were determined with inductively coupled plasma-mass spectrometry (ICP-MS) and inductively coupled plasma-atomic emission spectrometry (ICP-AES). Seventeen elements could be determined with reasonable acc...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:2:145
更新日期:2001-05-01 00:00:00
abstract::The aim of this study was to investigate the effects of the Toxoplasma gondii infection on the total content of the essential elements Zn and Mg levels. Plasma zinc and magnesium concentrations were measured in 158 patients whose anti-T gondii IgG antibodies were positive. Scores were obtained for the patients and the...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/BTER:92:1:11
更新日期:2003-04-01 00:00:00
abstract::Elemental analysis of archaeological bones, particularly for elements such as fluorine, strontium, and zinc, has been carried out for many years, with the aim of determining their age or relating their composition to diet. Bone samples are commonly dry ashed before analysis to remove organic material and render them m...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990417
更新日期:1990-06-01 00:00:00
abstract::The effect of increased selenium uptake on serum selenium in diabetic children was investigated during the first 9 yr of the Finnish nationwide selenium fertilization program, which started in 1984. Serum selenium concentrations were followed in 237 diabetic children (mean age 8.1 yr) and 214 controls from 1984 to 199...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790138
更新日期:1995-01-01 00:00:00
abstract::Body stores of lead, cadmium, and mercury are determined by the levels in the circulation, and their levels in blood may be related to hemoglobin levels and their absorption by soft tissue and bone. We investigated the association of body fat percentage, hemoglobin levels, and nutrient intakes with the blood concentra...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9566-7
更新日期:2013-03-01 00:00:00
abstract::This study aimed to determine the effect of excessive fluoride (F) on the morphological characteristics of the small intestine and the contents of serum cytokines in rats. A total of 48 3-week-old healthy female Sprague-Dawley rats were randomly divided into four groups (n = 12). The control group was given deionized ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1503-y
更新日期:2019-06-01 00:00:00
abstract::The aim of the present study was to investigate the effect of selenium (Se) deficiency on the expression of the toll-like receptor (TLR) signal transduction pathway in the spleen of chickens and explore the relationship between the TLR4/TRIF/NF-κB signaling pathway and inflammatory spleen injury. A total of 200 one-da...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02173-0
更新日期:2021-02-01 00:00:00
abstract::Although recent studies have shown that chromium (as the trivalent ion) is not an essential trace element, it has been demonstrated to generate beneficial effects at pharmacologically relevant doses on insulin sensitivity and cholesterol levels of rodent models of insulin insensitivity, including models of type 2 diab...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/s12011-015-0231-9
更新日期:2015-07-01 00:00:00
abstract::Concentrations of major nutritional and trace elements (Ca, P, Mg, Na, K, Fe, Zn, Cu, Mn, Se, Co, Cr, Ni, Sr, and Ba), as well as toxic heavy metals (Cd and Pb), were analyzed in the longissimus muscle of Charolais, Hereford, and Simmental bulls. The elements were determined using inductively coupled plasma optical em...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9913-y
更新日期:2014-04-01 00:00:00
abstract::Silicon (Si) is important for the growth and development of bone and connective tissues. Several studies have reported that Si supplementation improved bone mineral density (BMD) in female ovarectomized rats. However, few studies have investigated the effects of Si supplementation on bone status and bone metabolism in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9936-4
更新日期:2014-05-01 00:00:00
abstract::Over the last decade, there has been an increased concern about the health risks from exposure to arsenic at low doses, because of their neurotoxic effects on the developing brain. The exact mechanism underlying arsenic-induced neurotoxicity during sensitive periods of brain development remains unclear, although enhan...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1286-1
更新日期:2018-11-01 00:00:00
abstract::Electron energy loss spectroscopy (EELS) is a high spatial resolution electron microscopic technique with the potential to quantify elements at the subcellular level. The presence of each element is demonstrated by the electron energy loss edge at the energy characteristic of that element. The area of the edge may ind...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916819
更新日期:1994-01-01 00:00:00
abstract::Consumption of edible plants satisfies a significant part of human body needs in macro- and micronutrients while biologically active substances contain strong antioxidant properties and reduce the risk of a number of diseases. Balanced nutrition and design of personalized diets and treatment rely on the data on the co...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02345-y
更新日期:2020-08-19 00:00:00
abstract::Conflicting results exist between selenium concentration and preeclampsia. The role of selenium in the development of preeclampsia is unclear. We conducted a meta-analysis to compare the blood selenium level in patients with preeclampsia and healthy pregnant women, and to determine the effectiveness of selenium supple...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s12011-015-0545-7
更新日期:2016-06-01 00:00:00
abstract::Selenium is a trace element that, although toxic in higher concentrations, is essential for human and animal health. In this study, we looked at microarray-based gene expression patterns from liver and gastrocnemius tissues in mice fed either a selenium-deficient diet or diets containing sodium selenite, selenomethion...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8894-8
更新日期:2011-11-01 00:00:00
abstract::The molecular localization of maternal and fetal zinc and copper metalloproteins in diabetic and control rats was studied. Compared to controls, liver and kidneys of diabetic dams showed an increased concentration of zinc and copper that was associated with metallothionein. In contrast, fetuses of diabetic dams had lo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917490
更新日期:1988-12-01 00:00:00