The effect of diabetes on the molecular localization of maternal and fetal zinc and copper metalloprotein in the rat.

Abstract:

:The molecular localization of maternal and fetal zinc and copper metalloproteins in diabetic and control rats was studied. Compared to controls, liver and kidneys of diabetic dams showed an increased concentration of zinc and copper that was associated with metallothionein. In contrast, fetuses of diabetic dams had lower zinc and metallothionein levels than fetuses from controls. The abnormal maternal trace element metabolism seen with diabetes resulted in alterations of zinc uptake and/or retention of their fetuses.

journal_name

Biol Trace Elem Res

authors

Uriu-Hare JY,Stern JS,Keen CL

doi

10.1007/BF02917490

subject

Has Abstract

pub_date

1988-12-01 00:00:00

pages

71-9

eissn

0163-4984

issn

1559-0720

journal_volume

18

pub_type

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