Abstract：
:The binding of selenite, the form of selenium used in the treatment of Keshan disease, to plasma proteins and the role of erythrocytes in this process have been studied. The experiments were carried out by incubating 75Se as selenite with plasma and whole blood in vitro (human and rat) and in vivo (rat) and subsequent fractionation by Sephadex G-150 gel filtration. Human and rat plasma proteins were unable to incorporate selenium from selenite, as shown by the negligible amount present in proteins after incubation of plasma with selenite. The incorporation can be carried out after internalization of selenite by the erythrocytes in a fast, temperature dependent process. Hemoglobin, being the major binding protein for the newly reduced selenium in the erythrocyte, might have a role in the uptake of selenite by erythrocytes. The greater affinity of plasma proteins for the final selenium compound resulting from reduction could be the cause of the efflux. However, this is minimal in the absence of plasma, as is evident from the results obtained from blood reconstituted with saline solution instead of plasma. At least two proteins, one albumin like, probably albumin itself and the other of molecular weight close to or greater than 200,000 in the plasma, are involved in the binding and efflux processes.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Mas A,Jiang JY,Sarkar Bdoi
10.1007/BF02990129subject
Has Abstractpub_date
1988-01-01 00:00:00pages
97-110eissn
0163-4984issn
1559-0720journal_volume
15pub_type
杂志文章abstract：:Severe hyperhomocysteinemia (HHC) is associated with atherosclerosis. In hemodialysis (HD) patients, one of the main causes of death is cardiovascular disease. In animals, trace elements such as cobalt, copper, iron, and nickel ameliorated vitamin B(12) deficiency-induced HHC. However, correlations between plasma tota...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8139-2
更新日期：2008-09-01 00:00:00
abstract：:Silicon (Si) is important for the growth and development of bone and connective tissues. Several studies have reported that Si supplementation improved bone mineral density (BMD) in female ovarectomized rats. However, few studies have investigated the effects of Si supplementation on bone status and bone metabolism in...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-9936-4
更新日期：2014-05-01 00:00:00
abstract：:The original version of this article unfortunately contained a mistake. The name of "Ali Ghorbani Ranjbary" is now corrected in the author group of this article. The original article has been corrected. ...
journal_title：Biological trace element research
pub_type： 杂志文章,已发布勘误
doi：10.1007/s12011-019-01787-3
更新日期：2020-04-01 00:00:00
abstract：:The aim of this study was to investigate the effects of the Toxoplasma gondii infection on the total content of the essential elements Zn and Mg levels. Plasma zinc and magnesium concentrations were measured in 158 patients whose anti-T gondii IgG antibodies were positive. Scores were obtained for the patients and the...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1385/BTER:92:1:11
更新日期：2003-04-01 00:00:00
abstract：:Concentration of heavy metals (lead (Pb), cadmium (Cd), chromium (Cr), and copper (Cu)) was determined in the liver, gills, kidneys, and muscles of eight edible fish species (Channa punctata, Cirrhinus reba, Labeo rohita, Heteropneustes fossilis, Mystus cavasius, Oreochromis niloticus, Puntius sophore, and Wallago att...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-011-9011-3
更新日期：2011-12-01 00:00:00
abstract：:Magnesium (Mg) concentrations in diets have been associated with performance and eggshell quality of laying hens, but the results have been inconclusive. In this experiment, the effects of increasing concentrations of dietary Mg on productive performance and eggshell quality of aged laying hens were evaluated. A total...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9537-z
更新日期：2013-01-01 00:00:00
abstract：:The combination of excess mycotoxin exposure and selenium deficiency has been widely considered as a cause of Kashin-Beck disease (KBD). The present study aimed to investigate the expression profiles of selenium-related genes in human chondrocytes after exposure to T-2 toxin and deoxynivalenol (DON) and to preliminari...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1560-2
更新日期：2019-08-01 00:00:00
abstract：:Neonatal uptake of mercury (Hg) from milk was examined in a pregnant sheep model, where radioactive mercury (Hg203)/silver tooth fillings (amalgam) were newly placed. A crossover experimental design was used in which lactating ewes nursed foster lambs. In a parallel study, the relationship between dental history and b...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02785388
更新日期：1997-02-01 00:00:00
abstract：:This study was to investigate the alterations of serum copper homeostasis after hypertensive intracerebral hemorrhage (ICH), which is not yet clear. We recruited 85 hypertensive ICH patients and determined their serum levels of total copper (TCu), small molecule copper (SMC), and ceruloplasmin (Cp). Sera from 32 healt...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1227-4
更新日期：2018-09-01 00:00:00
abstract：:The aim of the study was to determine the role of alcoholic drinks as a potential source of dietary fluoride by means of measuring fluoride levels in selected alcoholic drinks available on the Polish market that are also diverse in terms of the percentage content of ethanol. The study was conducted on 48 types of drin...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0519-9
更新日期：2016-06-01 00:00:00
abstract：:The objective of this study was to investigate the iron source absorption in the small intestine of broiler. In situ ligated intestinal loops of 70 birds were poured into one of seven solutions, including inorganic iron (FeSO4, Fe2(SO4)3), organic Fe glycine chelate (Fe-Gly(II), Fe-Gly(III)), the mixtures (FeSO4 with ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0179-1
更新日期：2015-02-01 00:00:00
abstract：:The study was conducted to determine the effects of iron glycine chelate (Fe-Gly) on growth, tissue mineral concentrations, fecal mineral excretion, and liver antioxidant enzyme activities in broilers. A total of 360 1-day-old commercial broilers (Ross × Ross) were randomly allotted to six dietary treatments with six ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9418-5
更新日期：2012-11-01 00:00:00
abstract：:The aim of this study was to investigate the influence of Se deficiency on the transcription of inflammatory factors and selenoprotein genes in the kidneys of broiler chicks. One hundred fifty 1-day-old broiler chicks were randomly assigned to two groups fed with either a low-Se diet (L group, 0.033 mg/kg Se) or an ad...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0512-3
更新日期：2016-05-01 00:00:00
abstract：:The effects of zinc chloride (ZnCl2), disodium zinc ethylenediamine tetraacetate (Zn-EDTA), and zinc gluconate (Zn-GLU) on the antioxidant enzyme activities and levels of interleukins (ILs) in psoriasis-induced mice were studied. One hundred twenty female mice were randomly divided into six groups with 20 mice in each...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9799-0
更新日期：2013-12-01 00:00:00
abstract：:Daily ingestion of lead (Pb), even through piped drinking water, has long time been an important issue of concern, attracting for decades research in environmental science and toxicology, and again comes to prominence because of recent high-profile cases of exposure of populations in several countries to Pb-contaminat...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/s12011-018-1336-8
更新日期：2018-12-01 00:00:00
abstract：:The present study was undertaken to evaluate methylmercury-induced alterations in hepatic enzymes and oxidative stress markers in liver tissue of rainbow trout (Oncorhynchus mykiss) by using a perfusion method, and to explore possible protective effect of vitamin C against these alterations. Forty-eight fish were divi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0241-7
更新日期：2015-05-01 00:00:00
abstract：:The toxic effect of Pb2+ has been studied in eukaryotic cells by using Tetrahymena as a target. The maximum power (P(m)) and the growth rate constant (k) were determined, which showed that values of P(m) and k were linked to the concentration (C) of Pb2+. The addition of Pb2+ caused a decrease of the maximum heat prod...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-0055-3
更新日期：2007-11-01 00:00:00
abstract：:A dose-response experiment was conducted to find the sensitive and consistent biomarker for the estimation of dietary manganese (Mn) requirement and establish the optimal Mn level for broilers fed a practical corn-soybean meal diet from 1 to 21 days of age post-hatching. A total of 480 1-day-old Arbor Acres male chick...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8931-7
更新日期：2011-11-01 00:00:00
abstract：:The metabolic thermograms and heat output of mitochondria isolated from carp liver have been determined by using an LKB bioactivity monitor. The thermogram can be divided into four parts: the lag phase, active recovery phase, stationary phase, and decline phase. The thermokinetic equation was established for the activ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783314
更新日期：1997-10-01 00:00:00
abstract：:The present study investigated whether boron would enhance the action of 17beta-estradiol (E2) or parathyroid hormone (PTH) on bone mineral balance in ovariectomized (OVX) rats. Forty-three days after OVX, the rats were treated for 5 wk with vehicle, boron (5 ppm as boric acid), E2 (30 microg/kg/d, sc), PTH (60 microg...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:81:1:29
更新日期：2001-07-01 00:00:00
abstract：:The contribution of gamma-ray scattering to the total efficiency for point-source geometries in a gamma spectrometer was measured. Scattering of gamma-rays on the shield and in the sample was considered. For a 25% efficiency detector in a small shield, about a 1% contribution to the total efficiency was measured, wher...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917374
更新日期：1994-10-01 00:00:00
abstract：:This experiment was conducted to evaluate the effects of zinc (ZnSO4.H2O) and vitamin A (retinol) supplementation on performance, carcass characteristics, and serum concentrations of glucose, cholesterol, total protein, and malondialdehyde (MDA) as an indicator of lipid peroxidation in broiler chickens (Ross) reared a...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1385/BTER:94:3:225
更新日期：2003-09-01 00:00:00
abstract：:Selenium and mercuric chloride (MC) interactions regarding cellular uptake and selenium protection on MC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with MC (35 or 50 microM). Both treatment...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:81:3:229
更新日期：2001-09-01 00:00:00
abstract：:The levels of iron, zinc, and copper in the tissues of the pregnant rat, on d 12, 19, and 21 after impregnation have been determined and compared with controls. Iron levels decreased considerably in late pregnancy as a result of increased fetal requirements, thus diminishing iron stores in rat tissues, but maintaining...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917464
更新日期：1985-09-01 00:00:00
abstract：:Cadmium (Cd) is a highly toxic heavy metal that can affect human and animal health. Selenium (Se) is an essential microelement that can protect various organs against toxic heavy metals. Although many studies have investigated the adverse effect of Cd in rats and several other animals, little is known regarding the me...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1186-9
更新日期：2018-07-01 00:00:00
abstract：:Iron bioavailability seems to be regulated by vitamin A (VA) but the molecular events involved in this mechanism are not well understood. It is also known that retinoids mediate most of their function via interaction with retinoid receptors, which act as ligand-activated transcription factors controlling the expressio...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9397-6
更新日期：2012-10-01 00:00:00
abstract：:Biotransformation of inorganic arsenic in mammals is catalyzed by three serial enzyme activities: arsenate reductase, arsenite methyltransferase, and monomethylarsonate methyltransferase. Our laboratory has purified and characterized these enzymes in order to understand the mechanisms and elucidate the variations of t...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/BF02783907
更新日期：1999-06-01 00:00:00
abstract：:The study was conducted to evaluate the effects of chromium-loaded chitosan nanoparticles (Cr-CNP) on glucose transporter 4 (GLUT4), relevant messenger RNA (mRNA), and proteins involved in phosphatidylinositol 3-kinase (PI3K), Akt2-kinase, and AMP-activated protein kinase (AMPK) of skeletal muscles in finishing pigs. ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0890-1
更新日期：2017-07-01 00:00:00
abstract：:The purpose of the study was to determine the concentration of trace elements in serum samples of women who are chronic users of skin-whitening agents as well as the hepatic and renal effects of these agents on these women. The study was conducted among 23 skin-whitening users while 25 women served as the controls. Th...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-011-8962-8
更新日期：2011-12-01 00:00:00
abstract：:This study evaluated the microbial diversity of rooftop tank-stored drinking water consumed by Japanese quail (Coturnix coturnix japonica) using silver nanoparticles (AgNPs) and acetic acid (AC) and their mixture. Japanese quails (2 weeks old) of two different plumage colors, white and brown, were divided into four gr...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02422-2
更新日期：2020-10-08 00:00:00
