Functionalized Core-Shell Yttrium Oxide Nanoparticles as Antioxidants Agents in Heat Stressed Rats.

Abstract:

:Herein, we assess the antioxidant potential of core-shell yttrium oxide nanoparticles functionalized with ethylene glycol methacrylate phosphate (EGMP). The antioxidant properties of these nanoparticles were investigated in heat stressed models of 21 rats (heat stressed group, group B). Different samples of blood, serum, and tissue homogenate were collected at different time intervals in order to measure oxidative biomarkers such as enzymatic antioxidants (SODs, GPX, GST, GR, and TAC) and oxidative byproducts (MDA, PC, and 8-OHdG). Liver specimens of prophylactic group and heat stressed ones were also histopathologically examined 2 h post NPs injection. The measurements of oxidative biomarkers were complementary with histopathological findings and confirmed the antioxidant properties of poly EGMP yttrium oxide NPs.

journal_name

Biol Trace Elem Res

authors

Kassem S,Mohamed M,Sayour H,Canfarotta F,Piletsky S,Soliman MAM

doi

10.1007/s12011-020-02036-8

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

189-197

issue

1

eissn

0163-4984

issn

1559-0720

pii

10.1007/s12011-020-02036-8

journal_volume

198

pub_type

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