Abstract:
:A review of the activity of metal compounds in mammalian cell transformation assays has been completed. Results from these assays appear to correlate well with the known carcinogenic activity displayed by specific metal compounds in vivo. Studies of cell transformation in vitro may provide information pertaining to the mechanism of the induction of carcinogenesis by certain metals.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Daniel Heck J,Costa Mdoi
10.1007/BF02783248subject
Has Abstractpub_date
1982-06-01 00:00:00pages
71-82issue
2-3eissn
0163-4984issn
1559-0720journal_volume
4pub_type
杂志文章abstract::AFB1 is a mycotoxin which exerts their cytotoxicity through increasing oxidative damage in target organ. Kidney is one of target organs vulnerable to damage caused by AFB1. In this study, Madin-Darby canine kidney (MDCK) cells were used to evaluate the AFB1-induced cell damage by the MTT assay. The results revealed th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9887-9
更新日期:2014-03-01 00:00:00
abstract::In the affiliation section, Luiz Fabricio Zara's affiliation "Pontifical Catholic University of Goiás (PUC), Goiânia, GO, Brazil" was incorrect. The correct affiliation is College of Planaltina, UnB - University of Brasília, Distrito Federal, Brazil. ...
journal_title:Biological trace element research
pub_type: 杂志文章,已发布勘误
doi:10.1007/s12011-017-1195-8
更新日期:2018-05-01 00:00:00
abstract::The control of metallothionein (MT) synthesis was investigated in freshly prepared rat hepatocytes in experiments of short-term duration. Viability and metabolic function were maintained in incubations of 6-h duration. MT synthesis was measurable in hepatocytes from fed rats at Zn concentrations down to 1 microM. Zn a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783778
更新日期:1993-01-01 00:00:00
abstract::Trace element involvement in wounds left to heal by secondary intention needs clarification. We have previously reported faster healing of wounds following acute surgery compared with elective excision of pilonidal sinus disease. The effect of topical zinc on the closure of the excisional wounds was mediocre compared ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9658-z
更新日期:2013-06-01 00:00:00
abstract::Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy, and particularly seen in China. A deficiency of selenium and iodine is implicated as the main etiological factor for KBD. This meta-analysis aimed to evaluate the differences in the selenium and iodine levels between patients with KBD and healthy ...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析
doi:10.1007/s12011-015-0463-8
更新日期:2016-03-01 00:00:00
abstract::Instrumental epithermal neutron activation analysis was used in determining the halide concentration of camel serum. The halides determined were sodium, chloride, bromide, and iodide. Serum was examined when the camels had free access to drinking water, following 10 d of water restriction and 2 h following rapid rehyd...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02796697
更新日期:1987-04-01 00:00:00
abstract::Comparison of the clastogenic effects of antimony and bismuth used as trioxides, when administered orally by gavaging to laboratory bred male mice, showed that the former was more strongly clastogenic than the latter. Three doses of each chemical (400, 666.67, and 1000 mg/kg body wt), corresponding to 1/50, 1/30, and ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783802
更新日期:1993-05-01 00:00:00
abstract::The study was conducted to evaluate the effects of chromium-loaded chitosan nanoparticles (Cr-CNP) on glucose transporter 4 (GLUT4), relevant messenger RNA (mRNA), and proteins involved in phosphatidylinositol 3-kinase (PI3K), Akt2-kinase, and AMP-activated protein kinase (AMPK) of skeletal muscles in finishing pigs. ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0890-1
更新日期:2017-07-01 00:00:00
abstract::The present study aimed to investigate the prevalence of thrombocytopenia and its association with serum magnesium in a nationally representative cohort. A total of 8478 participants aged 18 years and over were recruited in a cross-sectional survey. Thrombocytopenia was defined as platelet count less than 150 × 10(9)/...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0406-4
更新日期:2016-01-01 00:00:00
abstract::The aim of this study was to investigate the relationships between the bronchopneumonia and mean concentrations of those trace elements in bronchoalveolar lavage fluid (BALF). Twenty-nine dogs were included this study (17 healthy dogs and 12 dogs with respiratory disease). Each BALF sample had been obtained during bro...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8149-0
更新日期:2008-07-01 00:00:00
abstract::This comparative study of the intestinal absorption of four toxic metals (aluminum, manganese, nickel, and lead) carried out in rats using the in situ intestinal perfusion technique was able to measure the partition of each metal between the intestine (intestinal retention), the blood circulation, and target tissues a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:99:1-3:157
更新日期:2004-07-01 00:00:00
abstract::In the current study, 48 male rats were classified into four groups (12 rats/group): 1-control group received 1 ml distilled water, 2-origanum oil group treated daily with oral dose of origanum oil (5 mg/kg) for 30 and 60 days, 3-mercuric chloride group treated daily with oral dose of mercuric chloride (4 mg/kg) for 3...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1067-2
更新日期:2018-03-01 00:00:00
abstract::To elucidate compositional changes of the pubic symphysis (PS) by aging, elements of pubic symphysis (PSs) removed from 26 cadavers were determined by inductively coupled plasma atomic-emission spectrometry. It was found that the relative contents (RCs) of calcium and phosphorus in women's PSs were about three- and fi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783243
更新日期:1997-01-01 00:00:00
abstract::The present study was undertaken to investigate the utility of cystatin C (CysC) as an early biomarker of cadmium (Cd)-induced renal injury. The study was carried out on 50 adult male individuals divided into five groups of 10 individuals as follows: control, welders, smoker welders, diabetic welders, and smoker diabe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9939-1
更新日期:2014-06-01 00:00:00
abstract::The glutathione transferase (GST) activity of rat liver cytosolic preparations with ethacrynic acid (EA) and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydro-benzo(a)pyrene (BPDE) as substrates, increased by 125 and 350%, respectively, in animals that had been treated with a single intraveno...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917265
更新日期:1989-07-01 00:00:00
abstract::Lead poisoning is a worldwide health problem, and its treatment is under investigation. The aim of this study was to access the efficacy of Coriandrum sativum (coriander) in reducing lead-induced changes in mice testis. Animal exposed to lead nitrate showed significant decrease in testicular SOD, CAT, GSH, total prote...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8553-0
更新日期:2010-09-01 00:00:00
abstract::Deficiency of intracellular magnesium (icMg) may coexist with normal serum Mg levels. Little is known about clinical and pharmacological factors affecting icMg in normomagnesemic patients with diabetes mellitus (DM). Moreover, no information exists regarding the icMg state in diabetic patients after acute illness and ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-8024-4
更新日期:2007-01-01 00:00:00
abstract::Interaction between toxic and essential elements is of particular interest, because the deficiency of essential element can dramatically increase the absorption rate of toxic metals inside the body. This study was conducted to evaluate the possible correlation of lead (Pb) with calcium (Ca), iron (Fe), and zinc (Zn) i...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1141-9
更新日期:2018-06-01 00:00:00
abstract::The effect of increased selenium uptake on serum selenium in diabetic children was investigated during the first 9 yr of the Finnish nationwide selenium fertilization program, which started in 1984. Serum selenium concentrations were followed in 237 diabetic children (mean age 8.1 yr) and 214 controls from 1984 to 199...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790138
更新日期:1995-01-01 00:00:00
abstract::Pituitary dwarfism (hGHD) is known to be associated with trace element deficiency, which causes improper functioning of the involved endocrine system. Previously, we reported on the head hair concentrations of zinc, copper, manganese, and iron from a total of 418 normal subjects (154 male and 264 female). In this repo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:85:2:127
更新日期:2002-02-01 00:00:00
abstract::The trace elements antimony, bromine, cesium, cobalt, iron, rubidium, scandium, strontium and zinc were determined by instrumental neutron activation analysis in breast tissue samples with fibrocystic disease and in samples with fibroadenoma tumors. The histological lesions of each breast sample with fibrocystic disea...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917337
更新日期:1994-10-01 00:00:00
abstract::The aim of this study was to assess the effect of sibutramine on mineral status and selected biochemical parameters in obese women. The study was conducted on 24 patients who received 15 mg daily doses of sibutramine for 12 weeks, and on 20 patients who received placebo. At the baseline, after the sixth and twelfth we...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9425-6
更新日期:2012-11-01 00:00:00
abstract::Descriptions of the effects of paraquat (P2+) on the peroxidation of liver microsomes are very divergent. Therefore, the presence of ferric iron in the medium and the activity of microsomal mixed-function oxidase system are two factors that we have taken into consideration to explain the discrepancies. The results sho...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790096
更新日期:1995-01-01 00:00:00
abstract::The aim of the present study was to investigate the effect of adding selenium (Se) in cereal production by fertilization on Se concentration in laying hen eggs. Tritordeum (×Tritordeum Ascherson et Graebner), a new cereal from the cross between durum wheat and a wild barley species having accreditation as natural crop...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0652-0
更新日期:2016-09-01 00:00:00
abstract::Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. A cross-sect...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1154-4
更新日期:2018-06-01 00:00:00
abstract::The objective was to evaluate metal ion accumulation in hair of patients undergoing orthodontic treatment with fixed appliances in time. The patients (N = 47) participated in a questionnaire survey. Hair sampling was performed at the beginning and in the 4th, 8th, and 12th month of the treatment. The content of metals...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-014-0152-z
更新日期:2015-02-01 00:00:00
abstract::Quin2, a fluorescent calcium probe, has a low affinity for calcium in comparison to its affinities for transition metal ions. Chelation of ferric ion with quin2 strongly enhanced the formation of oxidizing species in the presence of bolus H2O2 as detected with four assays, electron spin resonance with the spin-trap DM...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790098
更新日期:1995-01-01 00:00:00
abstract::The present study was designed to investigate the effect of mercuric chloride administration on copper, zinc, and iron concentrations in the liver, kidney, lung, heart, spleen, and muscle of rats. The results showed that after dose and time exposure to mercuric chloride, the concentration of mercury in the six tissues...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02910676
更新日期:1997-07-01 00:00:00
abstract::Selenium and methylmercuric chloride (MMC) interactions regarding cellular uptake and selenium protection on MMC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with (3.5 or 5 microM) MMC. Cells...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:3:251
更新日期:2001-06-01 00:00:00
abstract::Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is the most common human enzymopathy in the world. Trace elements are important for normal hematopoiesis and can play a role in acute hemolytic anemia induced by G-6-PD deficiency. For this purpose, we studied two groups consisting of 10 male children who are G-6-P...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:99:1-3:041
更新日期:2004-07-01 00:00:00