In vitro assessment of the toxicity of metal compounds : I. Mammalian Cell transformation.

Abstract:

:A review of the activity of metal compounds in mammalian cell transformation assays has been completed. Results from these assays appear to correlate well with the known carcinogenic activity displayed by specific metal compounds in vivo. Studies of cell transformation in vitro may provide information pertaining to the mechanism of the induction of carcinogenesis by certain metals.

journal_name

Biol Trace Elem Res

authors

Daniel Heck J,Costa M

doi

10.1007/BF02783248

subject

Has Abstract

pub_date

1982-06-01 00:00:00

pages

71-82

issue

2-3

eissn

0163-4984

issn

1559-0720

journal_volume

4

pub_type

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