Abstract：
:In the current study, 48 male rats were classified into four groups (12 rats/group): 1-control group received 1 ml distilled water, 2-origanum oil group treated daily with oral dose of origanum oil (5 mg/kg) for 30 and 60 days, 3-mercuric chloride group treated daily with oral dose of mercuric chloride (4 mg/kg) for 30 and 60 days, and 4-origanum oil + mercuric chloride group treated with both origanum oil and mercuric chloride (5 and 4 mg/kg, respectively) for 30 and 60 days. All treatments were carried out by stomach tube. The results showed that administration of mercuric chloride induced significant increase in thiobarbituric acid reactive substance (TBARS) and decrease in glutathione (GSH), catalase (CAT), and super oxide dismutase (SOD) in testis and spleen tissues. The data also showed significant increase in tumor necrossis factor-α (TNF-α), 8-hydroxy deoxyguanosine (8-OHDG), acid phosphatase (ACP), urea, and creatinine. Furthermore, significant decreases in serum zinc (Zn), copper (Cu), magnesium (Mg), iron (Fe), and testosterone in mercuric chloride group were recorded. The histological examination of testis and spleen tissues showed some degenerative changes while significant improvement in the antioxidant levels, biochemical, trace elements, and histological changes were observed in mercuric chloride group treated with origanum oil. It could be concluded that origanum oil through its antioxidant potential may possess health promoting properties and could protect cells from oxidative damage induced by mercuric chloride.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Mohamed NEdoi
10.1007/s12011-017-1067-2subject
Has Abstractpub_date
2018-03-01 00:00:00pages
49-56issue
1eissn
0163-4984issn
1559-0720pii
10.1007/s12011-017-1067-2journal_volume
182pub_type
杂志文章abstract：:Intraperitoneal administration of zinc chloride (ZnCl2) to Swiss albino mice in vivo induced a significant (p less than or equal to 0.05) increase in the frequencies of chromosomal aberrations of the bone-marrow cells at all concentrations used following acute (7.5, 10, 15 mg/kg body weight) and chronic (2.0, 3.0 mg/k...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02990346
更新日期：1991-08-01 00:00:00
abstract：:The k0 standardization method was adapted for NAA with stable low-flux reactors where flux monitors are not needed. The modified k0 method offers the convenience of the use of libraries of sensitivity constants. It was compared to the relative method for 52 elements using a SLOWPOKE reactor and 6 counting geometries. ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784232
更新日期：1999-01-01 00:00:00
abstract：:The influence of injection periods of 3-(1H-pyrrol-2-yl)-1H-indazole regarding vitamins A, E, C, selenium (Se), malondialdehyde (MDA) levels, and glutathione peroxidase (GSH-Px) activity in rats has been investigated. The substance was given by subcutaneous injection at 20 mg/kg every other day for a total of 15 injec...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8517-4
更新日期：2010-07-01 00:00:00
abstract：:This comparative study of the intestinal absorption of four toxic metals (aluminum, manganese, nickel, and lead) carried out in rats using the in situ intestinal perfusion technique was able to measure the partition of each metal between the intestine (intestinal retention), the blood circulation, and target tissues a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:99:1-3:157
更新日期：2004-07-01 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0669-4
更新日期：2016-11-01 00:00:00
abstract：:Recently, considerable attention has been paid to the negative effects caused by the presence and constant increase in concentration of heavy metals in the environment, as well as to the determination of their content in human biological samples. In this paper, the concentration of chromium in samples of blood and int...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1328-8
更新日期：2018-12-01 00:00:00
abstract：:Calsyntenin-2 (Clstn2) and calsyntenin-3 (Clstn3) are the members of the cadherin superfamily and function to regulate the postsynaptic activity. Both proteins are known to play an important role in memory and learning. This study was designed to test the hypothesis that exposure of mothers to Pb in drinking water may...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02241-5
更新日期：2020-06-16 00:00:00
abstract：:It has been defined that deficiency of trace elements plays an important role in the progression of asthma. However, the relationship between blood zinc (Zn), selenium (Se), and magnesium (Mg) and pulmonary functions in children remains to be clarified. A cross-sectional study was conducted in Wuxi, China, and a total...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-02019-4
更新日期：2020-10-01 00:00:00
abstract：:Despite the name, rare earth elements are relatively abundant in soil. Therefore, these elements might interact with biosphere during the history of life. In this study, we have examined the effect of rare earth ions on the growth of bacteria, fungi and soil nematode. All rare earth ions, except radioactive promethium...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0727-y
更新日期：2016-12-01 00:00:00
abstract：:An external-sample liquid scintillation (LS) counting for the gamma emitter 75Se has been developed. An expressly designed well-type LS vial and a 2,5-diphenyoxazole-1,4-bis(5-phenyl-2-oxazoyl)-benzene-xylene solution containing 35% tertrabutylzinn allow 75Se to be counted in a standard LS counter with counting effici...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:77:3:287
更新日期：2000-12-01 00:00:00
abstract：:Iron and copper are essential microminerals that are intimately related. The present study was performed to determine the effect of iron-deficiency anemia (IDA) and treatment with iron on laboratory indicators of copper status. Hemoglobin, mean corpuscular volume erythrocyte Zn protoporphyrin, serum ferritin, serum co...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:112:3:213
更新日期：2006-09-01 00:00:00
abstract：:In the mouse embryo cell line BALB/3T3 Clone A31-1-1, dose-dependent morphologic neoplastic transformation was obtained with NaAsO2, Na2HAsO4, CdCl2, and K2CrO4. Cellular uptake was four fold higher for As3+ than for As5+, and As5- was metabolized to As3+ in cytosol. Cytotoxicity and transformation rates were four fol...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917291
更新日期：1989-07-01 00:00:00
abstract：:The effects of cobaltous chloride in inducing chromosomal aberrations were observed on laboratory bred mice in vivo after single oral administration of different fractions (1/10, 1/20, 1/40) of the lethal toxic dose of the salt. Bone marrow cells were flushed out and processed for chromosome studies following colchici...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF03032691
更新日期：1991-05-01 00:00:00
abstract：:Selenium (Se) deficiency in the experimental models, Coturnix coturnix japonica and Corcyra cephalonica, resulted in impaired mitochondrial substrate oxidations and lowered thiol levels. Studies with respiratory inhibitors confirmed reduced mitochondrial electron transport enzyme activities, especially at cytochrome c...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784077
更新日期：1996-03-01 00:00:00
abstract：:To elucidate compositional changes of the mitral valve with aging, the authors investigated the relationships among element contents in the mitral valves. The subjects consisted of 10 men and 15 women, ranging in age from 65 to 102 yr. After the ordinary dissection, mitral valves, lower parts of the interventricular s...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:88:3:203
更新日期：2002-09-01 00:00:00
abstract：:Various studies indicate the role of manganese (Mn) in the virulence of pathogens. Salmonella is an intracellular pathogen which is able to multiply within the macrophages. The present study was therefore, designed to assess the effect of Mn supplementation on Salmonella-macrophage interactions particularly in referen...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8406-x
更新日期：2010-01-01 00:00:00
abstract：:The aim of the study was to determine the role of alcoholic drinks as a potential source of dietary fluoride by means of measuring fluoride levels in selected alcoholic drinks available on the Polish market that are also diverse in terms of the percentage content of ethanol. The study was conducted on 48 types of drin...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0519-9
更新日期：2016-06-01 00:00:00
abstract：:Differences in mineral nutrient composition of soils have been considered to affect health and population characteristics of free-ranging animals, particularly herbivores. Contents of Ca, Mg, and K in hair of female fawn white-tailed deer (Odocoileus virginianus) were measured for eight consecutive years to determine ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783968
更新日期：1998-06-01 00:00:00
abstract：:The effect of parenteral zinc on tissue metallothionein (MT) was studied in normal and streptozotocin-induced diabetic rats. The accumulation of Zn-MT in liver and pancreas of normal and diabetic rats following the administration (ip) of various amounts of zinc was not different. Renal Zn-MT was higher in the diabetic...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02795531
更新日期：1986-12-01 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02990451
更新日期：1981-06-01 00:00:00
abstract：:Cadmium (Cd) exposure has been recognized to result in a wide variety of cellular responses, including oxidative stress and body weight loss. The aim of the present study was to examine the effect of lycopene supplementation on the antioxidant defense system, lipid peroxidation (LPO) level, nitric oxide (NO), tumor ne...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-0027-7
更新日期：2007-08-01 00:00:00
abstract：:In present study, the levels of some toxic elements in 19 different home-made cosmetic products (spray hair dye, henna, tattoo, eyeliner, eye mascara, smear, lip moisturizer, and lipstick) were analyzed by inductively coupled plasma mass spectrometric (ICP-MS) after microwave digestion. The ICP-MS results were verifie...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02357-8
更新日期：2020-09-05 00:00:00
abstract：:Two experiments were conducted to study the performance, antioxidant activity, and bone mineral variables in broilers fed organic trace minerals (OTM) at lowered concentrations in the diet. In experiment 1, a total of 1500 day-old broiler male chicks were randomly distributed into six groups with 10 replicates of 25 c...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02481-5
更新日期：2020-11-20 00:00:00
abstract：:To examine whether there were differences between races in regard to age-related changes of elements and the relationships among elements in the arteries, the authors investigated both the renal arteries of Thai and Japanese. The Thai subjects consisted of 27 men and 11 women, ranging in age from 27 to 88 yr, whereas ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:106:3:219
更新日期：2005-09-01 00:00:00
abstract：:Significant disorders of liver metabolic pathways enzymes after high-cholesterol diet could give information on liver steatosis development. This process could probably also be inhibited by some compounds, as examined in rabbits. Forty-two male rabbits were served a high-cholesterol diet (2 g%) (0.67 g/kg b.m./24 h) w...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-0070-4
更新日期：2007-01-01 00:00:00
abstract：:A survey of mercury (Hg) and selenium (Se) contents was performed in fish collected from lakes located in two National Parks of the northern patagonian Andean range. Two native species, catfish (Diplomystes viedmensis) and creole perch (Percichthys trucha), and three introduced species, brown trout (Salmo trutta), rai...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-8059-6
更新日期：2008-04-01 00:00:00
abstract：:Naphthalene-1-acetic acid (HNAA), dichlorophenoxy acetic acid (HDAA), and indole-3-acetic acid (HIAA) are auxinhormones that can affect the growth of plants. The lanthanide complexes of the above auxinhormone LnA3 x 3H2O (Ln = La3+, Ce3+, Sm3+, Er3+, Yb3+; HA = HNAA, HDAA, HIAA; A = NAA-, DAA-, IAA-) were synthesized ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783322
更新日期：1998-07-01 00:00:00
abstract：:This study aimed to determine the effect of excessive fluoride (F) on the morphological characteristics of the small intestine and the contents of serum cytokines in rats. A total of 48 3-week-old healthy female Sprague-Dawley rats were randomly divided into four groups (n = 12). The control group was given deionized ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1503-y
更新日期：2019-06-01 00:00:00
abstract：:Among the trace elements, zinc is one of the most used elements in biological systems. Zinc is found in the structure of more than 2700 enzymes, including hydrolases, transferases, oxyreductases, ligases, isomerases, and lyases. Not surprisingly, it is present in almost all body cells. Preserving the stability and int...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/s12011-017-1119-7
更新日期：2018-05-01 00:00:00
abstract：:It has become evident over the last two decades that there is an intimate relationship between the trace elements and cancer. Some trace elements have been shown to be carcinogens, others appear to provide protection against cancer. Profound changes in trace element concentrations and distribution occur in patients wi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783817
更新日期：1979-08-01 00:00:00
