Abstract:
:Selenium (Se) deficiency in the experimental models, Coturnix coturnix japonica and Corcyra cephalonica, resulted in impaired mitochondrial substrate oxidations and lowered thiol levels. Studies with respiratory inhibitors confirmed reduced mitochondrial electron transport enzyme activities, especially at cytochrome c oxidase (COX), the terminal segment. Enhanced mitochondrial lipid peroxidation in Se deficiency was more pronounced in the heart tissue of the quail compared to other tissues. Glutathione peroxidase (GSH-Px) activity toward H2O2 and cumene hydroperoxide were generally low in the insect muscle tissue and activity toward H2O2 was maximal in the quail heart mitochondria that was not very sensitive to Se status. Lowered COX activity in Se deficiency was more directly correlated with the increased level of lipid peroxidation than with the GSH-Px activity measured, suggestive of Se mediated protective mechanisms independent of GSH-Px. Electron microscopic observations revealed structural changes such as loss of cristae with proliferative and degenerative changes of the mitochondria in Se deficiency. Involvement of Se in maintaining structure and functional efficiency of mitochondria is evident from the present study.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Rani P,Lalitha Kdoi
10.1007/BF02784077subject
Has Abstractpub_date
1996-03-01 00:00:00pages
225-34issue
3eissn
0163-4984issn
1559-0720journal_volume
51pub_type
杂志文章abstract::The concentrations of elements in urine obtained from cats with urolithiasis were compared with those of healthy cats. The concentration of several elements, such as sodium (Na), phosphorus (P), sulfur (S), and potassium (K), in urine obtained from cats with urolithiasis was significantly higher than that of healthy c...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8893-9
更新日期:2011-11-01 00:00:00
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journal_title:Biological trace element research
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
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doi:10.1007/BF02990487
更新日期:1994-07-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-015-0570-6
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journal_title:Biological trace element research
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doi:10.1007/s12011-012-9397-6
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1077-0
更新日期:2018-03-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0665-8
更新日期:2016-10-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF03032684
更新日期:1991-06-01 00:00:00
abstract::Renal functions were damaged at the reabsorptive site by the injection of cadmium-metallothionein (Cd-MT) and its effect on discrimination of chemically similar elements was examined for the two alkaline-earth elements, calcium (Ca) and strontium (Sr). Tubular damage was induced in female Wistar rats, 7 wk old, body w...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917418
更新日期:1989-10-01 00:00:00
abstract::Lithium is an integral drug used in the management of acute mania, unipolar and bipolar depression, and prophylaxis of bipolar disorders. Thyroid abnormalities have been associated with treatment with lithium. Zinc is an essential trace element that plays a role in several biological activities. Therefore, the present...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02356-9
更新日期:2020-08-26 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784090
更新日期:1996-04-01 00:00:00
abstract::Numerous experiments in vitro and in vivo have shown that an appropriate increase intake of silicon can facilitate the synthesis of collagen and its stabilization and promote the differentiation and mineralization of osteoblasts. In this study, we examined whether ortho-silicic acid restrains the differentiation of os...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02286-6
更新日期:2020-07-16 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02228-2
更新日期:2021-03-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:74:2:171
更新日期:2000-05-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8517-4
更新日期:2010-07-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0356-x
更新日期:2015-11-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1186-9
更新日期:2018-07-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:2003-08-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789141
更新日期:1990-01-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0512-3
更新日期:2016-05-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02479-z
更新日期:2021-01-07 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8726-x
更新日期:2011-06-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784001
更新日期:1992-04-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02788959
更新日期:1995-08-01 00:00:00
abstract::We investigated the effect of exercise on iron metabolism in horses. Four horses were walked on a mechanical walker for 1 wk (pre-exercise). They then performed moderate exercise on a high-speed treadmill in the first week of the exercise and relative high in the second week and high in the third week. Serum iron was ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:107:1:033
更新日期:2005-10-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02276-8
更新日期:2020-07-06 00:00:00
abstract::To examine whether the calcium accumulation in the arteries is related to the way of walk or not, the calcium contents were determined in various arteries of Japanese monkeys of quadrupedal walk by inductively coupled plasma-atomic emission spectrometry. Japanese monkeys consisted of five males and four females, rangi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:82:1-3:077
更新日期:2001-07-01 00:00:00