Abstract:
:Comparison of the clastogenic effects of antimony and bismuth used as trioxides, when administered orally by gavaging to laboratory bred male mice, showed that the former was more strongly clastogenic than the latter. Three doses of each chemical (400, 666.67, and 1000 mg/kg body wt), corresponding to 1/50, 1/30, and 1/20 of oral LD50 of antimony trioxide, were fed daily to sets of mice up to 21 d. Animals were sacrificed on day 7, 14, and 21 of the experiment. Chromosomal aberrations and mitotic index were studied from bone marrow cells following a colchicine-air drying Giemsa schedule. The frequencies of chromosomal aberrations induced by both chemicals were directly proportional to the dose used and the duration of exposure, indicating their cumulative effects on the organism. The highest dose of antimony, given for the longest period was, however, lethal. Effects on germ cells, as shown by screening for sperm head abnormalities, were not significant.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Gurnani N,Sharma A,Talukder Gdoi
10.1007/BF02783802subject
Has Abstractpub_date
1993-05-01 00:00:00pages
281-92issue
2-3eissn
0163-4984issn
1559-0720journal_volume
37pub_type
杂志文章abstract::Organotin compounds are highly versatile group of organometallic chemicals used in industrial and agricultural applications. Their endocrine-disrupting effects are well known and their extensive uses as biocide materials, e.g., in antifouling paints, for many years have led to serious environmental problems. So far, a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0144-z
更新日期:2014-12-01 00:00:00
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journal_title:Biological trace element research
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doi:10.1007/s12011-016-0861-6
更新日期:2017-05-01 00:00:00
abstract::Addition of zinc lowers the toxicity level of cadmium in cultured CHO cells. Cell survival and protein synthesis were used to measure the cellular toxicity of cadmium.(109)Cd was used to measure cadmium uptake by the cells. The results suggest that these class IIB transition metals, zinc and cadmium, share a common tr...
journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:1980-09-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02685933
更新日期:2007-05-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916542
更新日期:1985-02-01 00:00:00
abstract::Copper (Cu) and zinc (Zn) are involved in inflammatory process. This study was to investigate the clinical significance of Cu and Zn homeostasis alterations in acute appendicitis (AA). One hundred twenty-two AA patients and 102 healthy controls were enrolled in this study. Of which, 85 patients' appendixes were collec...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01661-2
更新日期:2019-12-01 00:00:00
abstract::This study was undertaken to evaluate a systematic analysis of mineral and trace elements of individual functionally determined parts of adult temporal bone. Marked differences were observed in basic structural elements (Ca, P, Mg, and Zn) among different bone regions. The more so, molar Ca/P ratio was significantly d...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF03032672
更新日期:1991-04-01 00:00:00
abstract::Modifications in the enzyme activity of lysozyme, a protein implied in the defence barrier of the organism, can be a good biomarker of alterations in the immune system as a result of exposure to toxic metal, such as lead. The aim of this work was to evaluate the effect of a 200 ppm dose of lead on lysozyme activity in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9446-1
更新日期:2012-12-01 00:00:00
abstract::In the mouse embryo cell line BALB/3T3 Clone A31-1-1, dose-dependent morphologic neoplastic transformation was obtained with NaAsO2, Na2HAsO4, CdCl2, and K2CrO4. Cellular uptake was four fold higher for As3+ than for As5+, and As5- was metabolized to As3+ in cytosol. Cytotoxicity and transformation rates were four fol...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917291
更新日期:1989-07-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02076-0
更新日期:2020-12-01 00:00:00
abstract::Responses of photosystem I and II activities of Microcystis aeruginosa to various concentrations of Cu(2+) were simultaneously examined using a Dual-PAM-100 fluorometer. Cell growth and contents of chlorophyll a were significantly inhibited by Cu(2+). Photosystem II activity [Y(II)] and electron transport [rETRmax(II)...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0039-z
更新日期:2014-08-01 00:00:00
abstract::Although fish consumption has positive health effects, metals accumulated in fish can cause human health risks. In this study, the levels of ten metals in rainbow trout (Oncorhynchus mykiss) farmed in the Keban Dam Reservoir, which has the biggest rainbow trout production capacity in Turkey, were determined and compar...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1156-2
更新日期:2018-07-01 00:00:00
abstract::Microcalorimetry was employed to investigate the action of Li(I) to aquatic ecosystem from the point view of bioenergetics. Tetrahymena thermophila BF5 was chosen as the model organism. The power-time curves of T. thermophila BF5 growth metabolism in the absence and presence of Li(I) were obtained. The corresponding t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-0040-x
更新日期:2007-10-01 00:00:00
abstract::As a nutritionally essential trace element, selenium (Se) is crucial for fish growth. However, the underlying mechanisms remain unclear. Fish somatic growth relies on the white muscle growth. This study aimed to explore the effects and underlying mechanisms of Se on fish white muscle growth using a juvenile rainbow tr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02282-w
更新日期:2020-07-14 00:00:00
abstract::The aim of this study was to analyze the effect of high dietary Fe on liver antioxidant status in mice fed a corn-oil-enriched diet. Male Balb/c mice were fed for 3 wk with a standard diet enriched with 5% by weight of corn oil with adequate Fe (FCO diet) or supplemented with 1% carbonyl Fe (FCOFe diet). The control g...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:113:2:177
更新日期:2006-11-01 00:00:00
abstract::To examine whether an accumulation of Ca in the tissues was accompanied by an increase of Mg, the authors investigated the relationships between Ca and Mg contents in the common iliac arteries, aortic valves, xiphoid processes, costal cartilages, posterior longitudinal ligaments, trigeminal nerves, and ribs by inducti...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:102:1-3:083
更新日期:2004-01-01 00:00:00
abstract::To elucidate compositional changes of the cardiac walls with development and aging, the authors investigated changes of elements in the atrial and ventricular walls of monkeys. The left and right atrial walls, left and right ventricular walls, and interatrial and interventricular septa were resected from the subjects....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:110:3:233
更新日期:2006-06-01 00:00:00
abstract::No specific treatment for COVID-19 infection is available up till now, and there is a great urge for effective treatment to reduce morbidity and mortality during this pandemic. We aimed to evaluate the effect of combining chloroquine/hydroxychloroquine (CQ/HCQ) and zinc in the treatment of COVID-19 patients. This was ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02512-1
更新日期:2020-11-27 00:00:00
abstract::Dietary Reference Intakes are not yet established for boron (B), a naturally occurring trace element in the human diet. Estimated dietary B intakes provide useful information for planning and assessing diets in healthy populations. The countries selected for this study represent a wide variety of dietary patterns and ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783128
更新日期:1998-01-01 00:00:00
abstract::Copper oxide nanoparticles (CuONPs) are widely used in several products and their release into the environment can cause toxicity to major food crops. In this study, toxic responses as a result of CuONPs exposure were studied in soybean (Glycine max L.) seedlings. The plants were grown in 1/2 strength Murashige and Sk...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0106-5
更新日期:2014-12-01 00:00:00
abstract::The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0477-2
更新日期:2016-04-01 00:00:00
abstract::Exposure of people and animals to arsenic (As) is a global public health concern because As is widely distributed and associated with numerous adverse effects. As is a poisonous metalloid and arsenic trioxide (As2O3) is a form of As. Thus far, there have been very few reports on the inflammatory factor alterations of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0305-8
更新日期:2015-10-01 00:00:00
abstract::Aluminum promotes osteoblast (OB) apoptosis. Apoptosis is induced by the disordered calcium homeostasis. Therefore, to investigate the relationship between Al-induced OB apoptosis and calcium homeostasis, calvarium OBs from neonatal rats (3-4 days) were cultured and exposed to 0.048-mg/mL Al(3+) or 0.048-mg/mL Al(3+) ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0417-1
更新日期:2016-02-01 00:00:00
abstract::Samples of Evernia prunastri, collected in a mountainous zone, were exposed in urban and highly industrialized areas in order to monitor the atmospheric pollution. Amounts of Cr, Mn, Fe, Ni, Cu, Zn, and Pb were determined by EDXRF spectrometry in secondary target excitation mode and in the thin film approach. An incre...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917318
更新日期:1994-10-01 00:00:00
abstract::Diabetic osteoporosis (DOP) is a complication of diabetes, with the characteristics of bone mineral density (BMD) reduction and bone structure destruction. Zinc was reported has a benefit effect on postmenopausal osteoporosise, it was also has hypoglycemic effect, whether zinc was beneficial on diabetes-induced osteop...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01810-7
更新日期:2020-04-01 00:00:00
abstract::Oxidative stress is a main factor in the pathogenesis of severe acute pancreatitis (SAP). The ability of zinc (Zn) to retard oxidative processes has been recognized for many years. This study aims to examine the levels of free oxygen radicals and antioxidant enzyme in SAP rats and know the effect of Zn supplementation...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9971-1
更新日期:2014-06-01 00:00:00
abstract::Selenium (Se) deficiency in the experimental models, Coturnix coturnix japonica and Corcyra cephalonica, resulted in impaired mitochondrial substrate oxidations and lowered thiol levels. Studies with respiratory inhibitors confirmed reduced mitochondrial electron transport enzyme activities, especially at cytochrome c...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784077
更新日期:1996-03-01 00:00:00
abstract::Concentrations of major nutritional and trace elements (Ca, P, Mg, Na, K, Fe, Zn, Cu, Mn, Se, Co, Cr, Ni, Sr, and Ba), as well as toxic heavy metals (Cd and Pb), were analyzed in the longissimus muscle of Charolais, Hereford, and Simmental bulls. The elements were determined using inductively coupled plasma optical em...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9913-y
更新日期:2014-04-01 00:00:00
abstract::The aim of this study was to investigate the effects of the Toxoplasma gondii infection on the total content of the essential elements Zn and Mg levels. Plasma zinc and magnesium concentrations were measured in 158 patients whose anti-T gondii IgG antibodies were positive. Scores were obtained for the patients and the...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/BTER:92:1:11
更新日期:2003-04-01 00:00:00
abstract::This in vitro study was designed to assess the impact of divalent (Fe(2+)) or trivalent (Fe(3+)) iron on the activity and oxidative balance of bovine spermatozoa at specific time intervals (0, 2, 8, 16, and 24 h) during an in vitro culture. Forty-five semen samples were collected from adult breeding bulls and diluted ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0288-5
更新日期:2015-09-01 00:00:00