Effect of zinc on cadmium influx and toxicity in cultured CHO cells.

Abstract:

:Addition of zinc lowers the toxicity level of cadmium in cultured CHO cells. Cell survival and protein synthesis were used to measure the cellular toxicity of cadmium.(109)Cd was used to measure cadmium uptake by the cells. The results suggest that these class IIB transition metals, zinc and cadmium, share a common transport mechanism. Thus, the antagonism appears to involve a reduction in the influx of cadmium due to the presence of zinc.

journal_name

Biol Trace Elem Res

authors

Huang PC,Smith B,Bohdan P,Corrigan A

doi

10.1007/BF02785356

subject

Has Abstract

pub_date

1980-09-01 00:00:00

pages

211-20

issue

3

eissn

0163-4984

issn

1559-0720

journal_volume

2

pub_type

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