Abstract：
:Exposure of cells to ionizing radiation leads to the formation of reactive oxygen species (ROS) that are associated with radiation-induced cytotoxicity. Because of the serious damaging potential of ROS, cells depend on the elaboration of the antioxidant defense system (AODS), both enzymatic and nonenzymatic oxidant defense mechanisms. The deficiency in important components of the endogenous AODS leads to the accumulation of oxidative stress inducing oxidative damage. The antioxidant enzymes superoxide dismutase and glutathione peroxidase are key intracellular antioxidants in the metabolism of ROS. In the current study, we investigated the potential role of these antioxidant enzymes in radioresistance during the evaluation of the compensatory role of some exogenous micronutrients against oxidative stress Animals were categorized into eight groups, receiving vitamin E (alpha-tocopherol) and/or selenium (Se) with or without whole-body gamma-irradiation (6.5 Gy). The results indicate that antioxidant pretreatments before irradiation may have some beneficial effects against irradiation-induced injury. The results also indicate that selenium and vitamin E act alone and in an additive fashion as radioprotecting agents. The results further suggest that selenium confers protection in part by inducing or activating cellular free-radical scavenging systems and by enhancing peroxide breakdown, whereas vitamin E appears to confer its protection by an alternate complementary mechanism.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Noaman E,Zahran AM,Kamal AM,Omran MFdoi
10.1385/BTER:86:1:55subject
Has Abstractpub_date
2002-04-01 00:00:00pages
55-64issue
1eissn
0163-4984issn
1559-0720journal_volume
86pub_type
杂志文章abstract：:Lead poisoning is a worldwide health problem, and its treatment is under investigation. The aim of this study was to access the efficacy of Coriandrum sativum (coriander) in reducing lead-induced changes in mice testis. Animal exposed to lead nitrate showed significant decrease in testicular SOD, CAT, GSH, total prote...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8553-0
更新日期：2010-09-01 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1141-9
更新日期：2018-06-01 00:00:00
abstract：:The objective of this study was to investigate the iron source absorption in the small intestine of broiler. In situ ligated intestinal loops of 70 birds were poured into one of seven solutions, including inorganic iron (FeSO4, Fe2(SO4)3), organic Fe glycine chelate (Fe-Gly(II), Fe-Gly(III)), the mixtures (FeSO4 with ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0179-1
更新日期：2015-02-01 00:00:00
abstract：:Zinc concentrations in the dorsal horn of spinal cord are important for wound healing, neurological function, and reproduction. However, the response of the spinal cord to alterations in dietary zinc is unknown in rats after spinal cord injury (SCI). The current study explored cellular zinc levels and zinc transporter...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9414-9
更新日期：2012-11-01 00:00:00
abstract：:In a controlled animal experiment the effects of dietary subacute Zn deficiency on growth, Zn concentration, and tissue 42-K distribution were studied. Growth retardation caused lower body weight because both skeletal and heart muscle showed a reduction in cell mass. Zn concentrations were reduced in most tissues, how...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02789301
更新日期：1994-12-01 00:00:00
abstract：:This study investigated the effects of ethanol (EtOH) on manganese (Mn)-induced striatal toxicity in rat by evaluating the neurobehavioral changes, biochemical and molecular events in rats exposed to Mn alone at 30 mg/kg, or their combination with EtOH at 1.25- and 5-g/kg body weight for 35 consecutive days. Locomotiv...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1587-4
更新日期：2019-09-01 00:00:00
abstract：:Women with gestational diabetes mellitus (GDM) may have lower serum selenium levels than healthy controls, which may be associated with preterm birth. We explored the association of serum selenium levels in early pregnancy with the risk of GDM and preterm birth among Chinese women. We included 398 women with a singlet...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02191-y
更新日期：2021-02-01 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02785277
更新日期：1998-07-01 00:00:00
abstract：:This study was performed with the aim of investigating the concentration of zinc and copper in the blood of healthy alpacas (Vicugna pacos) kept in central Europe and to compare the concentration of Zn and Cu in plasma and in whole blood. A further objective was to evaluate blood Zn and Cu in relation to different mic...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1043-x
更新日期：2018-02-01 00:00:00
abstract：:The control of metallothionein (MT) synthesis was investigated in freshly prepared rat hepatocytes in experiments of short-term duration. Viability and metabolic function were maintained in incubations of 6-h duration. MT synthesis was measurable in hepatocytes from fed rats at Zn concentrations down to 1 microM. Zn a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783778
更新日期：1993-01-01 00:00:00
abstract：:The consumption of vegetables grown on soils polluted by trace elements can cause a serious threat for animal and human health and disturb the functioning of the ecosystem. The aim of this work is to determine the concentrations of As, Cd, Co, Cr, Cu, Ni, Pb, Mn, and Zn in soils and different vegetables from market ga...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01849-6
更新日期：2020-05-01 00:00:00
abstract：:Guizhou black goats are essential to the production system in the Wumeng prairie in the Western China. This study aimed to determine the influence of nano-copper on antioxidant system in copper-deprived Guizhou black goats. We analyzed mineral contents in soil, forage, and goats' tissues. Blood parameters were also de...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02342-1
更新日期：2020-08-18 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/bter:84:1-3:197
更新日期：2001-01-01 00:00:00
abstract：:Mannheimia haemolytica is the main bacterial pathogen isolated in bovine respiratory disease (BRD), a common disease affecting calves before weaning. Previous research has shown that experimental infection with bovine herpesvirus 1, a respiratory virus, decreases plasma zinc (Zn) levels. However, changes in plasma Zn ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02145-4
更新日期：2021-01-01 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:80:1:53
更新日期：2001-04-01 00:00:00
abstract：:The concentrations of elements in urine obtained from cats with urolithiasis were compared with those of healthy cats. The concentration of several elements, such as sodium (Na), phosphorus (P), sulfur (S), and potassium (K), in urine obtained from cats with urolithiasis was significantly higher than that of healthy c...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8893-9
更新日期：2011-11-01 00:00:00
abstract：:A multitude of methods exists at present for the solubilization of biological tissues for atomic absorption analysis. We have examined several common methods of wet ashing using NBS bovine liver in order to determine which acids, acid combinations, or bases should be used as digesting agents for accurate and precise m...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02990451
更新日期：1981-06-01 00:00:00
abstract：:The present work aimed at assessing passive, innate, and acquired immunity in piglets from sows supplemented with either organic or inorganic selenium (Se). A total of 12 multiparous pregnant sows were randomly allocated to three groups: selenium-deficient, corn and soy-based diet base diet (BD), 0.3 mg Se/kg as hydro...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01754-y
更新日期：2020-03-01 00:00:00
abstract：:The humoral immune response was evaluated in male CD-1 mice fed the iron deficient (7 ppm Fe), iron sufficient (120 ppm Fe), and high-iron diets (3000 or 5000 ppm Fe) for 54 d. The IgM and IgG antibody responses against sheep erythrocytes (SRBC) determined by hemolytic plaque assay were suppressed by 65.4 and 51.2%, r...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02790075
更新日期：1994-10-01 00:00:00
abstract：:Copper (Cu) and zinc (Zn) are involved in inflammatory process. This study was to investigate the clinical significance of Cu and Zn homeostasis alterations in acute appendicitis (AA). One hundred twenty-two AA patients and 102 healthy controls were enrolled in this study. Of which, 85 patients' appendixes were collec...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01661-2
更新日期：2019-12-01 00:00:00
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journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/bter:89:3:277
更新日期：2002-12-01 00:00:00
abstract：:To elucidate compositional changes of the pubic symphysis (PS) by aging, elements of pubic symphysis (PSs) removed from 26 cadavers were determined by inductively coupled plasma atomic-emission spectrometry. It was found that the relative contents (RCs) of calcium and phosphorus in women's PSs were about three- and fi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783243
更新日期：1997-01-01 00:00:00
abstract：:Urine is a clinical specimen often used in medical diagnostics for monitoring of elements concentrations and kidneys function. We determined the contents of magnesium (Mg), calcium (Ca), zinc (Zn), copper (Cu), iron (Fe), lead (Pb), and cadmium (Cd) in 74 samples of 24-h urine (from 46 women and 28 men). The measureme...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8745-7
更新日期：2011-07-01 00:00:00
abstract：:Selenium (Se) is an essential trace element in animals and human, however, excess Se intake can result in adverse health effects. Se supplementation increased glutathione peroxidase (GSH-Px) and thioredoxin reductase (TR) expressions in Se-deficient rats. However, little information is available on the relationship be...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:89:2:165
更新日期：2002-11-01 00:00:00
abstract：:Nowadays, 70 % of global monogastric feeds contains an exogenous phytase. Phytase supplementation has enabled a more efficient utilisation of phytate phosphorous (P) and reduction of P pollution. Trace minerals, such as iron (Fe), zinc (Zn), copper (Cu) and manganese (Mn) are essential for maintaining health and immun...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0161-y
更新日期：2015-02-01 00:00:00
abstract：:A simple, quick procedure has been developed for preparation of human lenses for total chromium (Cr) analysis by electrothermal atomic absorption spectrometry (EAAS). This procedure involves wet ashing in a mini-autoclave with HNO3 and H2SO4. Recovery was 101.6%. This procedure is simple to carry out, does not generat...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784598
更新日期：1992-01-01 00:00:00
abstract：:The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However, no properly confirmed tumor regression was reported so...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/s12011-009-8486-7
更新日期：2010-06-01 00:00:00
abstract：:Concentrations of selected metals (Cu, Mn, Zn, Cd) in tea leaves were investigated. Samples included black, green, and other (red, white, yellow, and oolong) teas. They were purchased on a local market but they covered different countries of origin. Beverages like yerba mate, rooibos, and fruit teas were also included...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1140-x
更新日期：2018-06-01 00:00:00
abstract：:The contribution of gamma-ray scattering to the total efficiency for point-source geometries in a gamma spectrometer was measured. Scattering of gamma-rays on the shield and in the sample was considered. For a 25% efficiency detector in a small shield, about a 1% contribution to the total efficiency was measured, wher...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917374
更新日期：1994-10-01 00:00:00
abstract：:Selenium selenate was administered to streptozotocin-induced diabetic rats to assess its effects on the detrusor muscle. Thirty-two rats were divided into four groups of eight subjects each. The study animals were made diabetic by means of a single intravenous injection of streptozotocin (STZ). The responsiveness of t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:93:1-3:171
更新日期：2003-07-01 00:00:00
