Abstract:
:The seeds of Nelumbo nucifera (Lotus) have been used in the traditional system of medicine for various ailments including diabetes. The present study was aimed at analyzing the levels of biologically important trace elements in the lotus seeds by atomic absorption spectroscopy and evaluating the hypoglycemic properties of seed ash on streptozotocin-induced diabetes in rats. Diabetic rats treated with lotus seed ash at a concentration of 200 mg/kg body weight orally for 30 days exhibited significant hypoglycemic activity. The presence of trace elements in appreciable amounts in the seeds may play a direct or indirect role on insulin secretion or its action in a synergetic manner. The hypoglycemic activity of the ash was comparable with glyclazide. The role of trace elements in disorders related to diabetes is also discussed briefly.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Mani SS,Subramanian IP,Pillai SS,Muthusamy Kdoi
10.1007/s12011-010-8614-4subject
Has Abstractpub_date
2010-12-01 00:00:00pages
226-37issue
1-3eissn
0163-4984issn
1559-0720journal_volume
138pub_type
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