Abstract：
:The forms of Se in the Se-dependent enzyme formate dehydrogenase is known to be selenocysteine, but the way this amino acid enters the polypeptide chain has not been established. Through the use of a cysteine-requiring mutant ofEscherichia coli K-12 that could also grow in the presence of glutathione, we were able to study the effect of selenite, selenide, andL-selenocysteine, each at a concentration of 0.1 μM, on the synthesis of formate dehydrogenase. The three forms of Se served equally well for inducing formate dehydrogenase activity, measured by dichlorophenol-indophenol reduction mediated by phenazine methosulfate. It is known that selenite can be reduced to selenide by the action of glutathione reductase, present inE. coli, and that selenocysteine is converted to elemental Se by the action of selenocysteine lyase, also present in the mutant. Elemental Se is then reduced nonenzymatically to hydrogen selenide. The conversion of both selenite and selenocysteine to selenide and the ability of each form of Se to induce the synthesis of equal levels of formate dehydrogenase suggest that the incorporation of Se into formate dehydrogenase is accomplished by a posttranslational mechanism.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Karle JA,Shrift Adoi
10.1007/BF02795520subject
Has Abstractpub_date
1986-12-01 00:00:00pages
27-35issue
1eissn
0163-4984issn
1559-0720journal_volume
11pub_type
杂志文章abstract：:Sugar-borates (SBs) are mono- or di-sugar-borate esters (SBEs) comprised of one or two monosaccharide molecules linked to a boron (B) atom. SBEs occur naturally in commonly consumed herbs, vegetables, fruits, seeds, and nuts and, other than greatly varying levels of B found in local drinking water, are the primary nat...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/s12011-018-1550-4
更新日期：2019-03-01 00:00:00
abstract：:This study was undertaken to evaluate a systematic analysis of mineral and trace elements of individual functionally determined parts of adult temporal bone. Marked differences were observed in basic structural elements (Ca, P, Mg, and Zn) among different bone regions. The more so, molar Ca/P ratio was significantly d...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF03032672
更新日期：1991-04-01 00:00:00
abstract：:Mannheimia haemolytica is the main bacterial pathogen isolated in bovine respiratory disease (BRD), a common disease affecting calves before weaning. Previous research has shown that experimental infection with bovine herpesvirus 1, a respiratory virus, decreases plasma zinc (Zn) levels. However, changes in plasma Zn ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02145-4
更新日期：2021-01-01 00:00:00
abstract：:Over the last decade, there has been an increased concern about the health risks from exposure to arsenic at low doses, because of their neurotoxic effects on the developing brain. The exact mechanism underlying arsenic-induced neurotoxicity during sensitive periods of brain development remains unclear, although enhan...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1286-1
更新日期：2018-11-01 00:00:00
abstract：:The objective was to evaluate metal ion accumulation in hair of patients undergoing orthodontic treatment with fixed appliances in time. The patients (N = 47) participated in a questionnaire survey. Hair sampling was performed at the beginning and in the 4th, 8th, and 12th month of the treatment. The content of metals...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/s12011-014-0152-z
更新日期：2015-02-01 00:00:00
abstract：:Selenoprotein K (SelK), a member of selenoprotein family, is identified as a single endoplasmic reticulum (ER) transmembrane protein. Although over-expression of SelK inhibits adherence and migration of human gastric cancer BGC-823 cells, the effects of SelK in human choriocarcinoma (CCA) are not well understood. In t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1155-3
更新日期：2018-07-01 00:00:00
abstract：:Because nickel may have a biological function in a pathway in which vitamin B12 is important, an experiment was performed to determine the effects of nitrous oxide exposure in rats deprived of nickel. Exposure to nitrous oxide (N2O) causes inactivation of cobalamin and a subsequent decrease in the vitamin B12-dependen...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783980
更新日期：1993-07-01 00:00:00
abstract：:Experiments were conducted to determine whether the increased glutathione S-transferase (GSH-T) activity associated with selenium (Se) deficiency is necessarily related to losses in the activity of Se-dependent glutathione peroxidase (SeGSHpx) in chicks. Nutritional Se status was altered in two ways: by treatment with...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783792
更新日期：1993-05-01 00:00:00
abstract：:Woodlice are top consumers of a three-trophic system (soil, leaf litter, woodlice), and they are closely related to pollutant absorbing surfaces such as soil, leaf litter, and organic matter. We studied the effects of urbanization on trace element concentrations and fluctuating asymmetry of Armadillidium vulgare (Crus...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1454-3
更新日期：2019-05-01 00:00:00
abstract：:To elucidate whether the accumulation of elements occurred simultaneously in the various arteries with aging, the authors investigated age-related changes of elements in the eight arteries, such as the thoracic and abdominal aortas and the coronary, common carotid, pulmonary, splenic, common iliac, and uterine arterie...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02698081
更新日期：2007-07-01 00:00:00
abstract：:Daily ingestion of lead (Pb), even through piped drinking water, has long time been an important issue of concern, attracting for decades research in environmental science and toxicology, and again comes to prominence because of recent high-profile cases of exposure of populations in several countries to Pb-contaminat...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/s12011-018-1336-8
更新日期：2018-12-01 00:00:00
abstract：:Changes in the macro and trace element composition of saliva might be indicative for pathological changes in periodontal tissues. However, there is a lack of evidence in the literature showing associations between mineral elements and periodontal status. The aim of this study was to determine whether such associations...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01977-z
更新日期：2020-09-01 00:00:00
abstract：:Breast milk is considered the best source of nutrition for all infants. However, exposure of newborns to toxic metals is of special interest due to their potential harmful effects. Thus, the primary aims of this study were to determine the concentration of toxic heavy metals including lead, mercury, cadmium, and bariu...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1355-5
更新日期：2019-01-01 00:00:00
abstract：:Several studies have investigated the relationship between serum Se concentration and cervical cancer, but the results were inconsistent. Thus, we conducted a systematic review and meta-analysis to evaluate the association between serum selenium levels and cervical cancer. Twelve studies investigating the association ...
journal_title：Biological trace element research
pub_type： 杂志文章,meta分析
doi：10.1007/s12011-017-0982-6
更新日期：2017-10-01 00:00:00
abstract：:Exposure of cells to ionizing radiation leads to the formation of reactive oxygen species (ROS) that are associated with radiation-induced cytotoxicity. Because of the serious damaging potential of ROS, cells depend on the elaboration of the antioxidant defense system (AODS), both enzymatic and nonenzymatic oxidant de...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:86:1:55
更新日期：2002-04-01 00:00:00
abstract：:In vivo and in vitro studies were conducted to investigate the chemical forms by ion-exchange chromatography of selenium (Se) present in rat and ovine spermatozoa. After injection with 75Se-selenite, the form of 75Se in rat sperm was selenocysteine, but selenocysteine and selenomethionine (SeMet) were present in ovine...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/bter:76:2:161
更新日期：2000-08-01 00:00:00
abstract：:The use of phosphate fertilizers is essential in agriculture, because they supply farmland with nutrients for growing plants. However, heavy metals might be included as impurities in natural materials and minerals, so heavy metals can also be present in phosphate fertilizers or other chemical fertilizers. The aim of t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-011-9161-3
更新日期：2012-01-01 00:00:00
abstract：:Responses of photosystem I and II activities of Microcystis aeruginosa to various concentrations of Cu(2+) were simultaneously examined using a Dual-PAM-100 fluorometer. Cell growth and contents of chlorophyll a were significantly inhibited by Cu(2+). Photosystem II activity [Y(II)] and electron transport [rETRmax(II)...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0039-z
更新日期：2014-08-01 00:00:00
abstract：:To elucidate age-related changes of mineral contents in human veins, the relative contents (RCs) of elements in the human internal jugular veins, superior and inferior venae cavae, and femoral veins from 27 subjects ranging from 40 to 98 yr old were analyzed by inductively coupled plasma atomic emission spectrometry. ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02820017
更新日期：1998-04-01 00:00:00
abstract：:Vanadium, a trace element in human cells and regarded as an essential nutrient, plays an active role in all tissues. It is known that peroxovanadate-nicotinic acid (POV), a complex compound of vanadium, can decrease hyperglycemia; however, its biochemical mechanism remains unclear. The object of the present study is t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:74:3:237
更新日期：2000-06-01 00:00:00
abstract：:Urine is a clinical specimen often used in medical diagnostics for monitoring of elements concentrations and kidneys function. We determined the contents of magnesium (Mg), calcium (Ca), zinc (Zn), copper (Cu), iron (Fe), lead (Pb), and cadmium (Cd) in 74 samples of 24-h urine (from 46 women and 28 men). The measureme...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8745-7
更新日期：2011-07-01 00:00:00
abstract：:In vitro tests simulating the elements release from inhaled urban particulate matter (PM) with artificial lung fluids (Gamble's and Hatch's solutions) and simulated gastric and pancreatic solutions were applied for an estimation of hazardous element (As, Cd, Cr, Hg, Mn, Ni, Pb and Zn) bio-accessibility in this materia...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0101-x
更新日期：2014-11-01 00:00:00
abstract：:Interaction of elements in the course of element uptake by carrot (Daucas carota cv. U.S. harumakigosun) exerted by the addition of elements, such as Rb, Zn, and Al, was investigated. For the purpose of precise evaluation of uptake behavior, the simultaneous determination of absorption of Na, Be, Sr, Mn, Co, Zn, Ce, P...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/bter:84:1-3:197
更新日期：2001-01-01 00:00:00
abstract：:Arsenic (As) is widely distributed in our living environment and is useful for industry, agriculture, medical treatment, and other fields. Arsenic trioxide (As2O3) is an existing form of As. Exposure to As2O3 has a toxic effect on humans and animals. It not only leads to skin cancer, peripheral vascular disease, hyper...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0462-9
更新日期：2016-03-01 00:00:00
abstract：:Zinc (Zn) is an essential nutrient that is required in humans and animals for many physiological functions, including immune and antioxidant function, growth, and reproduction. The present study was performed to investigate the effects of three Zn levels, including Zn adequate (35.94 mg/kg, as a control), Zn deficienc...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:107:2:153
更新日期：2005-11-01 00:00:00
abstract：:Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbe...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8757-3
更新日期：2011-08-01 00:00:00
abstract：:In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic) and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed that the formaldehyde inhalation caused gradual decline of body...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8686-1
更新日期：2011-05-01 00:00:00
abstract：:The objective of this study was to investigate correlations between oxidative stress, metabolism of mineral elements, and lameness in dairy cows. Forty multiparous Chinese Holstein dairy cows were selected and divided into two groups (healthy vs lame, n = 20) by gait score. The experiment lasted for 60 days and sample...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0207-1
更新日期：2015-03-01 00:00:00
abstract：:The nuclear microscope is now gaining popularity in the field of life sciences. In particular, the combination of proton-induced X-ray emission to measure the elemental concentrations of inorganic elements, Rutherford backscattering spectrometry to characterize the organic matrix, and scanning transmission ion microsc...
journal_title：Biological trace element research
pub_type： 杂志文章,评审
doi：10.1007/BF02784192
更新日期：1999-01-01 00:00:00
abstract：:Both manganese and copper may affect bone synthesis. Bone content of both metals can be altered in alcoholics, although controversy exists regarding this matter. To analyse the relative and combined effects of ethanol and a low protein diet on bone copper and manganese, and their relationships with bone structure and ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-011-9296-2
更新日期：2012-06-01 00:00:00
