Abstract:
:Because nickel may have a biological function in a pathway in which vitamin B12 is important, an experiment was performed to determine the effects of nitrous oxide exposure in rats deprived of nickel. Exposure to nitrous oxide (N2O) causes inactivation of cobalamin and a subsequent decrease in the vitamin B12-dependent enzymes methionine synthase and methylmalonyl CoA mutase. Rats were assigned to dietary groups of 12 in a factorially arranged experiment with dietary variables of nickel (0 or 1 microgram/g) and vitamin B12 (0 or 50 ng/g). After 6 wk, one-half of the rats from each dietary group were exposed to 50% N2O/50% O2 for 90 min/d for the last 28 d of the experiment. Vitamin B12, N2O, or their interaction had numerous effects; classical findings included N2O-induced reduction in plasma vitamin B12 and decreases in the vitamin B12-dependent enzymes. Inactivation of vitamin B12 by N2O, however, did not exacerbate signs of nickel deprivation, possibly because the rats were able to metabolically compensate to N2O exposure.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Uthus EO,Poellot RAdoi
10.1007/BF02783980subject
Has Abstractpub_date
1993-07-01 00:00:00pages
35-46issue
1eissn
0163-4984issn
1559-0720journal_volume
38pub_type
杂志文章abstract::The influence of injection periods of 3-(1H-pyrrol-2-yl)-1H-indazole regarding vitamins A, E, C, selenium (Se), malondialdehyde (MDA) levels, and glutathione peroxidase (GSH-Px) activity in rats has been investigated. The substance was given by subcutaneous injection at 20 mg/kg every other day for a total of 15 injec...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8517-4
更新日期:2010-07-01 00:00:00
abstract::Concentrations of major nutritional and trace elements (Ca, P, Mg, Na, K, Fe, Zn, Cu, Mn, Se, Co, Cr, Ni, Sr, and Ba), as well as toxic heavy metals (Cd and Pb), were analyzed in the longissimus muscle of Charolais, Hereford, and Simmental bulls. The elements were determined using inductively coupled plasma optical em...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9913-y
更新日期:2014-04-01 00:00:00
abstract::In order to understand the normal and pathological physiologies of the epidermal cells, the simultaneous determination of several elements in the different cellular strata is of crucial importance. In recent years the electron microprobe (EMP) has become an established technique in this field. Its high spatial resolut...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02796687
更新日期:1987-04-01 00:00:00
abstract::The effects of lanthanum on heat production of mitochondria isolated from Wistar rat liver were investigated with microcalorimetry; simultaneously, the effects on mitochondrial swelling and membrane potential (Δψ) were determined by spectroscopic methods. La(3+) showed only inhibitory action on mitochondrial energy tu...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0269-8
更新日期:2015-09-01 00:00:00
abstract::Parenteral administration of mercuric chloride (HgCl2) to rats enhanced lipid peroxidation in liver, kidney, lung, testis, and serum (but not in heart, spleen, or muscle), as measured by the thiobarbituric acid reaction for malondialdehyde (MDA) in fresh tissue homogenates and body fluids. After sc injection of HgCl2 ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789461
更新日期:1996-05-01 00:00:00
abstract::The objective of this study was to determine the effect of systemic MgSO4 infusion on subendocardial and subepicardial perfusion. Seventeen spontaneously breathing piglets were examined. Myocardial perfusion was measured using radiolabeled microspheres at baseline, 30 and 60 min after either MgSO4 (80 mg/kg) or saline...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784442
更新日期:1997-12-01 00:00:00
abstract::Fruit juices are widely consumed in tropical countries as part of habitual diet. The concentrations of several minerals in these beverages were evaluated. Four commercially available brands of juices were analyzed for cadmium, lead, copper, zinc, aluminum, iron, chromium, manganese, and molybdenum. The levels ranged f...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9247-y
更新日期:2012-05-01 00:00:00
abstract::The serum copper and zinc levels were determined by atomic absorption spectrometry in 135 Hodgkin's disease (HD) patients and in 100 healthy controls. These values were used to explore the application value of the serum copper/zinc ratio in the histologic classification and prognosis in this illness. The resuls show t...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1385/bter:83:2:133
更新日期:2001-11-01 00:00:00
abstract::The objective of this study was to examine relations between basal metabolic rate (BMR) and cadmium (Cd) accumulation in the liver, kidneys, and duodenum in mice. The 5-month-old mice selected for high (H) and low (L) BMR were exposed for 8 weeks to 0, 10, and 100 μg Cd/mL of drinking water. The H-BMR mice showed sign...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9061-6
更新日期:2011-12-01 00:00:00
abstract::Aluminum promotes osteoblast (OB) apoptosis. Apoptosis is induced by the disordered calcium homeostasis. Therefore, to investigate the relationship between Al-induced OB apoptosis and calcium homeostasis, calvarium OBs from neonatal rats (3-4 days) were cultured and exposed to 0.048-mg/mL Al(3+) or 0.048-mg/mL Al(3+) ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0417-1
更新日期:2016-02-01 00:00:00
abstract::Vanadium compounds maintain euglycemic effects in diabetic rats long after drug withdrawal and bis(α-furancarboxylato)oxovanadium(IV) (BFOV) possesses potent antidiabetic effects in diabetic rats. Here, we investigated the treatment and posttreatment effects of BFOV in diabetic Kuo Kondo [1, 2] with Ay gene (KKAy) mic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9689-5
更新日期:2013-06-01 00:00:00
abstract::Serum copper and zinc estimations in humans were made to find their diagnostic and prognostic value in cases of myocardial infarction. Following infarction, there was an increase in serum copper levels from the first 24 h up to the 7th day, with gradual decline that did not reach the normal value up to the 14th day. T...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990200
更新日期:1991-12-01 00:00:00
abstract::Dietary Reference Intakes are not yet established for boron (B), a naturally occurring trace element in the human diet. Estimated dietary B intakes provide useful information for planning and assessing diets in healthy populations. The countries selected for this study represent a wide variety of dietary patterns and ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783128
更新日期:1998-01-01 00:00:00
abstract::Microbeam X-ray spectrometry, energy-dispersive X-ray fluorescence analysis, and neutron activation analysis were evaluated for the detection of selenium contained in the selenoprotein glutathione peroxidase. The glutathione peroxidase had been previously separated using polyacrylamide gel electrophoresis. The use of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917328
更新日期:1994-10-01 00:00:00
abstract:UNLABELLED:There is conflicting evidence regarding the relationship between magnesium deficiency and metabolic syndrome, and a systematic assessment of the literature has not been performed. Our objective was to clarify the association between magnesium levels and metabolic syndrome by performing a meta-analysis. Based...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析
doi:10.1007/s12011-015-0446-9
更新日期:2016-03-01 00:00:00
abstract::Trace element contamination in Chinese herbal medicines has been recognized as a potential health concern for consumers. To assess the health risk to the herb-consuming population, nine trace elements (Cu, Cd, Cr, Mo, Ni, Pb, Sr, Zn, and As) were investigated based on their concentrations in three common medicinal pla...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02539-4
更新日期:2021-01-03 00:00:00
abstract::The risk of premature ovarian failure (POF) increases in association with alteration in immunological parameters and oxidative stress (OS). Adequate intake of trace elements is required for antioxidant property and immune defense mechanism. The aim of this study was to explore the involvement of trace elements, OS, an...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1197-6
更新日期:2018-08-01 00:00:00
abstract::Heavy metals toxicity is a prevalent health problem particularly in developing countries. Mercury and cadmium are toxic elements that have no physiologic functions in human body. They should not be present in the human body by any concentration. Copper, on the other hand, is one of the elements that are essential for ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0525-y
更新日期:2016-06-01 00:00:00
abstract::Trace minerals and vitamins are known modulators of bone metabolism, and dietary optimization of these components may improve skeletal development and reduce the occurrence of skeleton deformities in farmed fish. As for larval stages, mineral and water-soluble vitamin nutrition requirements are lacking in research eff...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01939-5
更新日期:2020-08-01 00:00:00
abstract::Although lead is known to induce arterial hypertension and vascular damage, it is not clear if after cessation of lead treatment, the increase of blood pressure is sustained and the vascular function is different from untreated rats. Therefore, we aimed to evaluate the systolic blood pressure during and following lead...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0497-y
更新日期:2016-04-01 00:00:00
abstract::The hypothesis was tested that marginal copper deficiency affects iron status. Copper restriction (1 vs 5 mg Cu/kg diet) significantly lowered iron concentrations and transferrin saturation in plasma and reduced blood hemoglobin, hematocrit, and iron concentrations in tibia and femur, but raised iron concentrations in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02786240
更新日期:1992-10-01 00:00:00
abstract::The present study was designed to investigate the effects of montmorillonite (MMT) on dietary Cd-induced oxidative damage in liver and kidney of carp (Carassius auratus). One hundred eighty carp were randomly divided into four groups and fed with a basal diet, a basal diet supplemented with 0.5% MMT, Cd-comtaminated b...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8735-9
更新日期:2011-06-01 00:00:00
abstract::The effect of increased selenium uptake on serum selenium in diabetic children was investigated during the first 9 yr of the Finnish nationwide selenium fertilization program, which started in 1984. Serum selenium concentrations were followed in 237 diabetic children (mean age 8.1 yr) and 214 controls from 1984 to 199...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790138
更新日期:1995-01-01 00:00:00
abstract::This study evaluated the effects of supplemental dietary chromium (Cr) on the performance, carcass traits, and some serum parameters of broilers under a heat stress (23.9 to 37 °C cycling) condition. A total of 150 1-day-old broiler chicks (Cobb 500) according to a completely randomized design were assigned into five ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9663-2
更新日期:2013-06-01 00:00:00
abstract:CONTEXT:Complementary alternative medicine therapies based on the use of cesium chloride preparations for the treatment of cancer and radiation poisoning, have generated therapeutic interest; but oral or intravenous administration of cesium chloride (CsCl) to cancer patients as an alternative mode of cancer therapy hav...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:94:2:97
更新日期:2003-08-01 00:00:00
abstract::In 47 children with malignancy, zinc status, growth, and performance during standard treatment were compared with those in controls. At diagnosis, growth was retarded and hair zinc values were high, 2.4 +/- 0.7 mumol/g, as in chronic deficiency. During induction therapy, serum declined to 10.4 +/- 2.3 mumol/L and urin...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02991414
更新日期:1991-09-01 00:00:00
abstract::In this study, lead acetate solution and porcine cerebral hydrolysate peptides (PCHPs) were administered to developing mice. Porcine cerebral protein pretreated by ultrasound was hydrolyzed with alcalase, and 11 peptide fragments were obtained by Matrix-assisted laser desorption ionization-time of flight mass spectrom...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0329-0
更新日期:2015-12-01 00:00:00
abstract::The purpose of current study was to determine the step at which dietary selenium (Se) regulates the transcriptional expression of the gene for Se-glutathione peroxidase (Se-GPx) in rat brain and transplanted glioma tissue. Wistar rats were fed a Se-free diet or the same diet supplemented with 0.5, 2.0, and 4.0 mg Se/k...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:73:1:67
更新日期:2000-01-01 00:00:00
abstract::The study was conducted to determine the effects of iron glycine chelate (Fe-Gly) on growth, tissue mineral concentrations, fecal mineral excretion, and liver antioxidant enzyme activities in broilers. A total of 360 1-day-old commercial broilers (Ross × Ross) were randomly allotted to six dietary treatments with six ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9418-5
更新日期:2012-11-01 00:00:00
abstract::The inhibition of thymidine incorporation by inadequate availability of zinc induced by adding a chelator to the culture medium was significantly less in human cell lines than in rodent cell lines. In contrast, zinc uptake into the human cells was inhibited by the chelator to a greater extent than with rodent cells. T...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02788961
更新日期:1995-08-01 00:00:00