Abstract：
:In 47 children with malignancy, zinc status, growth, and performance during standard treatment were compared with those in controls. At diagnosis, growth was retarded and hair zinc values were high, 2.4 +/- 0.7 mumol/g, as in chronic deficiency. During induction therapy, serum declined to 10.4 +/- 2.3 mumol/L and urinary excretion increased to 5.3 +/- 2.8 mumol/mol creatinine, as in acute exacerbation of deficiency. Control CSF values in children in remission, 0.04 +/- 0.01 mumol/L, were lower than reference values in adults. No difference in mean CSF zinc was observed during therapy, or in those with acute lymphoblastic leukemia (1) at high risk, (2) with central nervous system involvement, (3) with low performance, or (4) resistant to therapy. In six children unexplained values, up to 0.28 mumol/L during induction, were measured. No correlations between the various zinc parameters were found.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Van Wouwe JP,van Zuylen Ldoi
10.1007/BF02991414subject
Has Abstractpub_date
1991-09-01 00:00:00pages
197-204issue
3eissn
0163-4984issn
1559-0720journal_volume
30pub_type
杂志文章abstract：UNLABELLED:Limited data are available indicating the effects of chromium administration on endocrine profiles, biomarkers of inflammation, and oxidative stress among women with polycystic ovary syndrome (PCOS). This study was done to assess the effects of chromium administration on endocrine profiles, biomarkers of inf...
journal_title：Biological trace element research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12011-015-0570-6
更新日期：2016-07-01 00:00:00
abstract：:Selenium selenate was administered to streptozotocin-induced diabetic rats to assess its effects on the detrusor muscle. Thirty-two rats were divided into four groups of eight subjects each. The study animals were made diabetic by means of a single intravenous injection of streptozotocin (STZ). The responsiveness of t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:93:1-3:171
更新日期：2003-07-01 00:00:00
abstract：:Inducing the differentiation of stem cells from human exfoliated deciduous teeth (SHEDs) proceeds with low efficiency, which greatly limits clinical applications. Divalent metal elements play an important role in osteoinductivity for bone remodeling because they can simulate bone formation and decrease bone resorption...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1256-7
更新日期：2018-10-01 00:00:00
abstract：:In order to study the metabolism of mercury (Hg), its affinity to metallothionein (MT), and its influence on levels of the essential metals copper and zinc in the brain tissue of rats exposed to elemental mercury (HgO) vapor was investigated. The major findings were: 1. After long-term exposure, about 40% of mercury w...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02789402
更新日期：1993-04-01 00:00:00
abstract：:Magnesium (Mg) concentrations in diets have been associated with performance and eggshell quality of laying hens, but the results have been inconclusive. In this experiment, the effects of increasing concentrations of dietary Mg on productive performance and eggshell quality of aged laying hens were evaluated. A total...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9537-z
更新日期：2013-01-01 00:00:00
abstract：:The objective of the study was analysis of hair trace elements content in children with goiter living in Aktubinsk region. Children with goiter and age- and sex-adjusted controls were involved in the current study. Hair trace elements content was assessed using inductively coupled plasma mass spectrometry. Thyroid vol...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/s12011-016-0711-6
更新日期：2016-12-01 00:00:00
abstract：:Osteoporosis is a bone disease that leads to an increased risk of fracture. Oxidative stress may play a major role in the development of osteoporosis in part by inhibiting osteoblastic differentiation of bone marrow stromal cells (MSCs). Some evidence suggested that antioxidant selenium could prevent osteoporosis, but...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9488-4
更新日期：2012-12-01 00:00:00
abstract：:The seeds of Nelumbo nucifera (Lotus) have been used in the traditional system of medicine for various ailments including diabetes. The present study was aimed at analyzing the levels of biologically important trace elements in the lotus seeds by atomic absorption spectroscopy and evaluating the hypoglycemic propertie...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8614-4
更新日期：2010-12-01 00:00:00
abstract：:Hyperlipidemia is one of the major risk factors for atherosclerosis and ischemic heart disease. Chromium (Cr) mineral is playing a crucial role in glucose and lipid homeostasis. The aim of this study was to evaluate the protective effects of combined chromium picolinate (CrPic) and atorvastatin treatment against hyper...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1010-6
更新日期：2017-12-01 00:00:00
abstract：:Selenium is a trace element that has antioxidant and neuroprotective effects. The aim of this study is to investigate the effects of selenium in reducing ischemia-reperfusion injury of the gastrocnemius muscle. In this experimental study, 80 adult male Wistar rats weighing 250-300 g were divided into ten groups (N = 8...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0218-y
更新日期：2015-04-01 00:00:00
abstract：:The aim of this research was to assess plasma magnesium (Mg) concentration, the frequencies of activated T CD4+ and T CD8+ lymphocytes and B lymphocytes in adolescents with hyperthyroidism due to Graves' disease (GD), and to assess changes in the above-mentioned parameters during methimazole (MMI) treatment. The frequ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9690-z
更新日期：2013-06-01 00:00:00
abstract：:The variance of testing was compared between the College of American Pathologists clinical survey and that of a recent review about hair mineral testing. The review suggested that the accuracy of hair mineral testing was unreliable. In general, there was a greater range of variance in the College of American Pathologi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:87:1-3:001
更新日期：2002-07-01 00:00:00
abstract：:The influence of dietary supplementation with thiamine on lead (Pb) contents in blood and tissues, blood δ-aminolevulinic acid dehydratase (δ-ALAD) activity, and urinary excretion of δ-aminolevulinic acid (δ-ALA) was evaluated in male Sprague-Dawley rats. Groups of randomly selected animals were given a thiamine-defic...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02795566
更新日期：1986-08-01 00:00:00
abstract：:The aim of this study was to investigate the protective effects of erdosteine and vitamins C and E (VCE) on the lungs after performing hind limb ischemia-reperfusion (I/R) by assessing oxidative stress, plasma copper (Cu), and zinc (Zn) analysis. The animals were divided randomly into four groups as nine rats each as ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-0010-3
更新日期：2007-07-01 00:00:00
abstract：:The intervention effect of fucoxanthin, which is reportedly a powerful antioxidant, on cadmium-induced thyroid damage in mice was evaluated. Animals (N = 120) were divided into control group (given pure water, N = 20) and CdCl2-exposed group (given CdCl2 orally at a dose of 30 mg/kg body weight (bw)/day for 30 days, N...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02291-9
更新日期：2020-07-21 00:00:00
abstract：:This comparative study of the intestinal absorption of four toxic metals (aluminum, manganese, nickel, and lead) carried out in rats using the in situ intestinal perfusion technique was able to measure the partition of each metal between the intestine (intestinal retention), the blood circulation, and target tissues a...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:99:1-3:157
更新日期：2004-07-01 00:00:00
abstract：:Synaptosomes are used as an ex vivo model in the investigation of neuronal transmission and neurodegenerative processes. In this study, we aimed to determine the protective effects of boric acid (BA) and curcumin, which have antioxidant and anti-inflammatory properties, on Aβ1-42 induced neurodegenerative damage. Syna...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02511-2
更新日期：2020-11-25 00:00:00
abstract：:Zinc is an essential micronutrient for the organism and is critical for the functional and structural integrity of cells. Determination of the amount of trace element concentrations in tissues such as hair samples have been used for the evaluation of the metabolic status especially in children. Unlike serum zinc, conc...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02115-w
更新日期：2020-08-01 00:00:00
abstract：:The objective of the present study was to investigate the relationship between hair essential trace element and mineral content and ADHD in preschool (4-6 years old) and primary school children (6-10 years old) in relation to age and gender. Hair essential trace element and mineral content in 90 Russian children with ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01947-5
更新日期：2020-08-01 00:00:00
abstract：:The degree of accumulation and distribution of Cd and Pb in the organs of young animals compared to the amount taken in with water or feed have not been thoroughly investigated yet. The experiment aimed to verify whether the source of toxic metals (feed, drinking water) administered to growing rats orally has an influ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0414-4
更新日期：2016-02-01 00:00:00
abstract：:The effect ofin utero zinc deficiency on fetal development in rats is reviewed. Attention is paid to the primary biochemical lesion associated with zinc-related teratogenesis and special consideration is given to the central nervous system. Evidence is presented that the thymidine kinase salvage pathway, used for the ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02916569
更新日期：1985-03-01 00:00:00
abstract：:Serum iron levels have been shown to decline both with fever and with strenuous exercise, leading to the supposition that the decrease might be the result of a rise in core body temperature. To evaluate this hypothesis, the serum iron response to an exercise-induced 1.5 degrees C rise in core body temperature was meas...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:108:1-3:061
更新日期：2005-01-01 00:00:00
abstract：:The tissue distribution of 14 elements was simultaneously determined in rats 28 d after hypophysectomy (HPY), thyroparathyroidectomy (TPTY), adrenalectomy (ADY), and castration (CTN). The elements Na, K, Ca, Mg, Fe, S, P, Rb, Sr, Mn, Cu, and Zn were investigated in whole blood, plasma, brain, liver, kidney, heart, ske...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02797096
更新日期：1988-07-01 00:00:00
abstract：:This study aimed to investigate the effects of vitamin D and magnesium co-supplementation on muscle strength and function, body composition, and inflammation in vitamin D-deficient middle-aged women. In this study, 83 healthy middle-aged women (40-55 years) with vitamin D deficiency were randomly assigned into two gro...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02387-2
更新日期：2020-09-21 00:00:00
abstract：:Deficiency of intracellular magnesium (icMg) may coexist with normal serum Mg levels. Little is known about clinical and pharmacological factors affecting icMg in normomagnesemic patients with diabetes mellitus (DM). Moreover, no information exists regarding the icMg state in diabetic patients after acute illness and ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-007-8024-4
更新日期：2007-01-01 00:00:00
abstract：:The risk of premature ovarian failure (POF) increases in association with alteration in immunological parameters and oxidative stress (OS). Adequate intake of trace elements is required for antioxidant property and immune defense mechanism. The aim of this study was to explore the involvement of trace elements, OS, an...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1197-6
更新日期：2018-08-01 00:00:00
abstract：:Nonenzymatic glycation of long-lived proteins has been implicated in several complications related to age and diabetes. Dicarbonyl compounds such as methylglyoxal (MGO) have been identified as the predominant source for the formation of advanced glycation end-products (AGEs) in various tissues. We investigated the eff...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8915-7
更新日期：2011-11-01 00:00:00
abstract：:Copper is an essential trace element with various biological functions. Excess copper, however, is extremely toxic, leading to many pathological conditions that are consistent with oxidative damage to membranes and molecules. Exposure to high levels of copper results in various changes in the tissues. In liver, hypert...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:96:1-3:209
更新日期：2003-01-01 00:00:00
abstract：:Obesity, a chronic inflammatory state, is associated with altered zinc metabolism. ZnT and Zip transporters are involved in the regulation of zinc metabolism. This study examined the relationships among obesity, zinc transporter gene expression, and inflammatory markers in young Korean women. The messenger RNA (mRNA) ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-9902-1
更新日期：2014-04-01 00:00:00
abstract：:Studies were designed to characterize the plasma membrane polypeptide composition of normal rat kidney (NRK) and virus-transformed NRK cells as a function of time following iron deprivation. Using this approach we found that rapid depletion of iron from the cells increases the amounts of two membrane-associated glycop...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02821711
更新日期：1979-06-01 00:00:00
