Abstract:
:The solubility of both free and low molecular weight ligand complexed calcium, magnesium, and zinc in skimmed human and bovine milks over intestinal luminal pH ranges (approximately 3-7) was measured using ultrafiltration techniques. Some of the experimental difficulties associated with the separation of labile metal ion ligand components from milks by ultrafiltration techniques are discussed. Experimental methods designed to minimize interferences in mineral ultrafiltrations from milks are outlined. Mineral solubilities in skimmed human and bovine milks are compared to data obtained in a previous study using milk models. The solubility of zinc in both skimmed bovine and bovine model milks is less than in human and human model milks at the higher pHs, characteristic of the luminal region where zinc absorption is thought to occur. The decrease in zinc solubility is caused by the coprecipitation of zinc with calcium phosphate, particularly in bovine milk samples. If solubility at the higher pHs is a requisite for zinc absorption then the enhanced bioavailability of zinc from human milk may be related to the detrimental element-compound interaction discussed in this study.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Brushmiller JG,Ames RW,Jacobs FA,Nelson LSdoi
10.1007/BF02925450subject
Has Abstractpub_date
1989-01-01 00:00:00pages
71-92issue
1-2eissn
0163-4984issn
1559-0720journal_volume
19pub_type
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