Intraluminal chemistry of zinc in milks.

Abstract:

:The solubility of both free and low molecular weight ligand complexed calcium, magnesium, and zinc in skimmed human and bovine milks over intestinal luminal pH ranges (approximately 3-7) was measured using ultrafiltration techniques. Some of the experimental difficulties associated with the separation of labile metal ion ligand components from milks by ultrafiltration techniques are discussed. Experimental methods designed to minimize interferences in mineral ultrafiltrations from milks are outlined. Mineral solubilities in skimmed human and bovine milks are compared to data obtained in a previous study using milk models. The solubility of zinc in both skimmed bovine and bovine model milks is less than in human and human model milks at the higher pHs, characteristic of the luminal region where zinc absorption is thought to occur. The decrease in zinc solubility is caused by the coprecipitation of zinc with calcium phosphate, particularly in bovine milk samples. If solubility at the higher pHs is a requisite for zinc absorption then the enhanced bioavailability of zinc from human milk may be related to the detrimental element-compound interaction discussed in this study.

journal_name

Biol Trace Elem Res

authors

Brushmiller JG,Ames RW,Jacobs FA,Nelson LS

doi

10.1007/BF02925450

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

71-92

issue

1-2

eissn

0163-4984

issn

1559-0720

journal_volume

19

pub_type

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