Interaction between essential elements selenium and zinc with cadmium and mercury in samples from hypertensive patients.

Abstract:

:The abnormal metabolism of metal ions plays an important role in health and disease conditions; hence, the studies about them have received much interest. The objective of this study was to evaluate the association between trace and toxic elements zinc (Zn), cadmium (Cd), selenium (Se), and mercury (Hg) in biological samples (scalp hair, blood, and urine) of hypertensive patients (n = 257), residents of Hyderabad, Pakistan. For comparison purpose, the biological samples of age-matched healthy controls were selected as referents. The concentrations of trace and toxic elements were measured by atomic absorption spectrophotometer prior to microwave-assisted acid digestion. The validity and accuracy of the methodology was checked using certified reference materials and by the conventional wet acid digestion method. The recovery of all studied elements was found in the range of 96.4-99.1 % in certified reference materials. The results of this study showed that the mean values of Cd and Hg were significantly higher in scalp hair, blood, and urine samples of hypertensive patients than in referents (P < 0.001), whilst the concentrations of Zn and Se were lower in the scalp hair and blood, but higher in the urine samples of hypertensive patients. The deficiency of Zn and Se and the high exposure of toxic metals may be synergistic with risk factors associated with hypertension.

journal_name

Biol Trace Elem Res

authors

Afridi HI,Kazi TG,Talpur FN,Kazi A,Arain SS,Arain SA,Brahman KD,Panhwar AH,Naeemullah,Shezadi M,Ali J

doi

10.1007/s12011-014-0048-y

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

185-96

issue

2

eissn

0163-4984

issn

1559-0720

journal_volume

160

pub_type

杂志文章
  • Effects of zinc glycine chelate on oxidative stress, contents of trace elements, and intestinal morphology in broilers.

    abstract::Three hundred and sixty healthy Ross × Ross 1-day-old broilers were used to study the effects of zinc glycine chelate (Zn-Gly) on oxidative stress, contents of trace elements, and intestinal morphology. All broilers were randomly assigned to six treatment groups, which replicates three times. Diets were as follows: (1...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8824-9

    authors: Ma W,Niu H,Feng J,Wang Y,Feng J

    更新日期:2011-09-01 00:00:00

  • A Cross-sectional Study of Plasma Trace Elements and Vitamins Content in Androgenetic Alopecia in Men.

    abstract::Androgenetic alopecia (AGA) is the most common variant of male pattern baldness in which occurrence and development of multiple genetic, hormonal, and metabolic factors are involved. We aimed to estimate plasma element content (Mg, Ca, Zn, Cu, Se, Fe), vitamin status (B12, D, E, and folic acid) in patients with AGA us...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02468-2

    authors: Kondrakhina IN,Verbenko DA,Zatevalov AM,Gatiatulina ER,Nikonorov AA,Deryabin DG,Kubanov AA

    更新日期:2020-11-05 00:00:00

  • Trace Elements in the Large Population-Based HUNT3 Survey.

    abstract::The Nord-Trøndelag Health Study (The HUNT Study) is a large health survey population study in the county of Trøndelag, Norway. The survey has been repeated four times in about 10-year intervals. In the HUNT3 survey (2006-2008), we collected 28,000 samples for trace element analysis. Blood samples from 758 healthy pers...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02376-5

    authors: Syversen T,Evje L,Wolf S,Flaten TP,Lierhagen S,Simic A

    更新日期:2020-09-08 00:00:00

  • Effect of dietary zinc on the levels and distribution of Fatty acids and vitamin A in blood plasma chylomicrons.

    abstract::The aim of this work was to explore the effects of a low- and high-zinc diet and vitamin Aon the distribution of fatty acids in chylomicrons. Mongolian Gerbils were fed a basal diet (for 3 wk) containing 8 or 38 mg zinc/kg of feed (low-zinc group [termed LZ group] and saturated zinc group [termed SZ group], respective...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:112:2:145

    authors: Cerovic A,Miletic I,Sobajic S,Blagojevic D,Jones DR,Poznanic M,Radusinovic M

    更新日期:2006-08-01 00:00:00

  • Dietary Selenium Promotes Somatic Growth of Rainbow Trout (Oncorhynchus mykiss) by Accelerating the Hypertrophic Growth of White Muscle.

    abstract::As a nutritionally essential trace element, selenium (Se) is crucial for fish growth. However, the underlying mechanisms remain unclear. Fish somatic growth relies on the white muscle growth. This study aimed to explore the effects and underlying mechanisms of Se on fish white muscle growth using a juvenile rainbow tr...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02282-w

    authors: Wang L,Zhang D,Li S,Wang L,Yin J,Xu Z,Zhang X

    更新日期:2020-07-14 00:00:00

  • Serum zinc and copper in myocardial infarction with particular reference to prognosis.

    abstract::Serum copper and zinc estimations in humans were made to find their diagnostic and prognostic value in cases of myocardial infarction. Following infarction, there was an increase in serum copper levels from the first 24 h up to the 7th day, with gradual decline that did not reach the normal value up to the 14th day. T...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02990200

    authors: Jain VK,Mohan G

    更新日期:1991-12-01 00:00:00

  • Selenium and Iodine Levels in Subjects with Kashin-Beck Disease: a Meta-analysis.

    abstract::Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy, and particularly seen in China. A deficiency of selenium and iodine is implicated as the main etiological factor for KBD. This meta-analysis aimed to evaluate the differences in the selenium and iodine levels between patients with KBD and healthy ...

    journal_title:Biological trace element research

    pub_type: 杂志文章,meta分析

    doi:10.1007/s12011-015-0463-8

    authors: Yang L,Zhao GH,Yu FF,Zhang RQ,Guo X

    更新日期:2016-03-01 00:00:00

  • Presence of Toxic Heavy Metals in Platelet-Rich Fibrin: a Pilot Study.

    abstract::Platelet-rich fibrin (PRF) is widely used blood-derived biomaterial which is directly applied to the surgical wounds. Depending on its autologous origin, PRF is thought as a safe material. However, it is not known to what extent the blood-derived toxins can be found in the PRF by considering the systemic exposure rate...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01695-6

    authors: Yaprak E,Yolcubal İ

    更新日期:2019-10-01 00:00:00

  • Some improvements in the quality of NAA procedures and the reliability of the results.

    abstract::After considering the need for quality control in NAA, the concept of quality in NAA procedures themselves is discussed, and some important factors identified. Two approaches to improve quality are then described in more detail. The first concerns the unique ability of NAA using different isotopic reactions and differ...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审

    doi:10.1007/BF02917356

    authors: Byrne AR

    更新日期:1994-10-01 00:00:00

  • Effect of peroxovanadate compound on phenylalanine hydroxylase gene expression.

    abstract::Vanadium, a trace element in human cells and regarded as an essential nutrient, plays an active role in all tissues. It is known that peroxovanadate-nicotinic acid (POV), a complex compound of vanadium, can decrease hyperglycemia; however, its biochemical mechanism remains unclear. The object of the present study is t...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:74:3:237

    authors: Wang YL,Yu B

    更新日期:2000-06-01 00:00:00

  • Serum Trace Elements and Electrolytes Are Associated with Fasting Plasma Glucose and HbA1c in Postmenopausal Women with Type 2 Diabetes Mellitus.

    abstract::The primary aim of the research was to assess the level of trace elements and electrolytes in serum of postmenopausal diabetic women. Sixty-four postmenopausal women with type 2 diabetes mellitus (DM2) and 64 age- and body mass index-matched controls were examined. Serum trace elements were assessed using inductively ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-016-0868-z

    authors: Skalnaya MG,Skalny AV,Yurasov VV,Demidov VA,Grabeklis AR,Radysh IV,Tinkov AA

    更新日期:2017-05-01 00:00:00

  • Effects of taurine on oxidative stress parameters and chromium levels altered by acute hexavalent chromium exposure in mice kidney tissue.

    abstract::The kidney has been regarded as a critical organ of toxicity induced by acute exposure to hexavalent chromium [Cr(VI)] compounds. Reactive intermediates and free radicals generated during reduction process might be responsible for Cr(VI) toxicity. In this study, the effects of pretreatment or posttreatment of taurine ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:102:1-3:209

    authors: Boşgelmez II,Güvendik G

    更新日期:2004-01-01 00:00:00

  • Selenium reduces mobile phone (900 MHz)-induced oxidative stress, mitochondrial function, and apoptosis in breast cancer cells.

    abstract::Exposure to mobile phone-induced electromagnetic radiation (EMR) may affect biological systems by increasing free oxygen radicals, apoptosis, and mitochondrial depolarization levels although selenium may modulate the values in cancer. The present study was designed to investigate the effects of 900 MHz radiation on th...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-0032-6

    authors: Kahya MC,Nazıroğlu M,Çiğ B

    更新日期:2014-08-01 00:00:00

  • Serum levels of Cu, Se, and Zn in adult rural/urban residents in Ghana: paradigm shift?

    abstract::Deficiencies in Cu, Se, and Zn impair one or more biochemical functions, and excess are associated with toxicity. Baseline studies on the Ghanaian population are scanty. The study was undertaken to determine whether significant rural/urban differences in the serum levels of Cu, Se, and Zn did exist. Forty males/60 fem...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-009-8571-y

    authors: Asare GA,Nani A

    更新日期:2010-11-01 00:00:00

  • Lipid peroxidation in rats administrated with mercuric chloride.

    abstract::Parenteral administration of mercuric chloride (HgCl2) to rats enhanced lipid peroxidation in liver, kidney, lung, testis, and serum (but not in heart, spleen, or muscle), as measured by the thiobarbituric acid reaction for malondialdehyde (MDA) in fresh tissue homogenates and body fluids. After sc injection of HgCl2 ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02789461

    authors: Huang YL,Cheng SL,Lin TH

    更新日期:1996-05-01 00:00:00

  • Effect of form of iron on nickel deprivation in the rat : Liver content of copper, iron, manganese, and zinc.

    abstract::In three fully crossed, factorially arranged, completely randomized experiments, female weanling rats were fed a basal diet (containing about 10 ng of nickel and 2.3 μg of iron/g) supplemented with graded levels of nickel and iron. Iron was supplemented to the diet in experiment 1 at levels of 0, 25, 50, and 100 μg/g ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02990121

    authors: Nielsen FH,Shuler TR

    更新日期:1981-09-01 00:00:00

  • The Determination of Toxic Metals in some Traditional Cosmetic Products and Health Risk Assessment.

    abstract::In present study, the levels of some toxic elements in 19 different home-made cosmetic products (spray hair dye, henna, tattoo, eyeliner, eye mascara, smear, lip moisturizer, and lipstick) were analyzed by inductively coupled plasma mass spectrometric (ICP-MS) after microwave digestion. The ICP-MS results were verifie...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02357-8

    authors: Kilic S,Kilic M,Soylak M

    更新日期:2020-09-05 00:00:00

  • Blood selenium status in normal Punjabi population of Pakistan.

    abstract::Selenium concentrations in the blood of 112 (56 females and 56 males) normal subjects, from different regions of the Punjab (Pakistan), have been determined using the technique of inductively coupled plasma-mass spectrometry. The whole blood selenium concentrations were found to be 452 ± 12 ppb (parts per billion or n...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8867-y

    authors: Alvi FM,Chaudhri MA,Watling J,Hasnain S

    更新日期:2011-10-01 00:00:00

  • Serum selenium levels in diabetic children. A followup study during selenium-enriched agricultural fertilization in Finland.

    abstract::The effect of increased selenium uptake on serum selenium in diabetic children was investigated during the first 9 yr of the Finnish nationwide selenium fertilization program, which started in 1984. Serum selenium concentrations were followed in 237 diabetic children (mean age 8.1 yr) and 214 controls from 1984 to 199...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02790138

    authors: Wang WC,Mäkelä AL,Näntö V,Mäkelä P

    更新日期:1995-01-01 00:00:00

  • Age-related changes of elements in renal arteries of Thai and Japanese and the relationships among elements.

    abstract::To examine whether there were differences between races in regard to age-related changes of elements and the relationships among elements in the arteries, the authors investigated both the renal arteries of Thai and Japanese. The Thai subjects consisted of 27 men and 11 women, ranging in age from 27 to 88 yr, whereas ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:106:3:219

    authors: Mahakkanukrauh P,Tohno S,Tohno Y,Azuma C,Ongkana N,Moriwake Y,Minami T

    更新日期:2005-09-01 00:00:00

  • Effects of High-Dose of Copper Amino Acid Complex on Laying Performance, Hematological and Biochemical Parameters, Organ Index, and Histopathology in Laying Hens.

    abstract::The objective of the study was to evaluate the maximum tolerance limit of amino acid copper complex (Cu-Lys-Glu) for laying hens by measuring their laying performance, hematological and serum biochemical parameters, organ index, and histopathology. A total of 450 18-week-old Beijing White layers were randomly allocate...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02406-2

    authors: Zhou Q,Zhu J,Liu B,Qiu J,Lu X,Curtin B,Ji F,Yu D

    更新日期:2020-10-12 00:00:00

  • Stimulation of urinary copper excretion by trientine((R)) in nickel-sensitive patients.

    abstract::Trientine((R)) is not an effective drug for the treatment of intractable hand dermatitis in nickel-sensitive patients. In a controlled, double-blind study this chelator, on oral administration, failed to stimulate nickel excretion. Early morning urine samples from two groups of nine patients were analyzed by atomic ab...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02795597

    authors: McMaster D,Burrows D,Eedy DJ,Love AH

    更新日期:1987-10-01 00:00:00

  • Influence of the coat color on the trace elemental status measured by particle-induced X-ray emission in horse hair.

    abstract::The influence of hair color on the trace elemental status in horse's hair has been studied. A current analytical technique such as particle-induced X-ray emission (PIXE) used in this study has provided reliable, rapid, easy, and relatively inexpensive diagnostic methods. Twenty-eight elements (Al, Br, Ca, Cl, Co, Cu, ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:103:2:169

    authors: Asano K,Suzuki K,Chiba M,Sera K,Matsumoto T,Asano R,Sakai T

    更新日期:2005-02-01 00:00:00

  • Autophagy May Be Involved in Fluoride-Induced Learning Impairment in Rats.

    abstract::Fluoride can induce neurotoxicity, but the mechanism is not clear. In this study, we explored the role of autophagy in F--induced neurotoxicity of Wistar rats. Eighty Wistar rats were randomly divided into four groups: the control group (distilled water containing less than 0.1 mg/L F-) and three NaF-treated groups (F...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-019-01735-1

    authors: Zhang C,Huo S,Fan Y,Gao Y,Yang Y,Sun D

    更新日期:2020-02-01 00:00:00

  • The effect of a moderate zinc deficiency and dietary fat source on the activity and expression of the Δ(3)Δ (2)-enoyl-CoA isomerase in the liver of growing rats.

    abstract::Auxiliary enzymes participate in β-oxidation of unsaturated fatty acids. The objective of the study was to investigate the impact of a moderate zinc deficiency and a high intake of polyunsaturated fat on Δ(3)Δ(2)-enoyl-CoA isomerase (ECI) in the liver and other tissues. Five groups of eight weanling rats each were fed...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-014-9940-8

    authors: Justus J,Weigand E

    更新日期:2014-06-01 00:00:00

  • Enrichment, Distribution of Vanadium-Containing Protein in Vanadium-Enriched Sea Cucumber Apostichopus japonicus and the Ameliorative Effect on Insulin Resistance.

    abstract::Sea cucumbers are a potential source of natural organic vanadium that may improve insulin resistance. In this work, vanadium was accumulated rapidly in blood, body wall, and intestine by sea cucumber Apostichopus japonicus. Furthermore, water-soluble vanadium-containing proteins, the main form of the organic vanadium,...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0517-y

    authors: Liu Y,Zhou Q,Zhao Y,Wang Y,Wang Y,Wang J,Xu J,Xue C

    更新日期:2016-05-01 00:00:00

  • Oxidative stress during selenium deficiency in seedlings of Trigonella foenum-graecum and mitigation by mimosine Part II. Glutathione metabolism.

    abstract::Adaptive alterations in glutathione (GSH) metabolism were studied during oxidative stress induced by selenium (Se) deficiency in germinating seedlings of Trigonella foenum-graecum grown for 72 h and the response to supplementation individually of Se or mimosine was explored. Growth enhancement with improved mitochondr...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783830

    authors: Santosh TR,Sreekala M,Lalitha K

    更新日期:1999-12-01 00:00:00

  • Smoking does not influence cadmium concentrations in blood and urine in relatively high levels of environmental cadmium areas in Japan.

    abstract::We examined how the influence of smoking on blood and urinary cadmium (Cd) concentrations was modified by the level of environmental Cd. We measured blood and urinary Cd concentrations of 1134 men over 50 yr of age in three areas in Japan that were exposed to different levels of environmental Cd. Analysis of variance ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:110:2:107

    authors: Uetani M,Kobayashi E,Suwazono Y,Nishijo M,Nakagawa H,Kido T,Nogawa K

    更新日期:2006-05-01 00:00:00

  • Effects of selenium-chitosan on blood selenium concentration, antioxidation status, and cellular and humoral immunity in mice.

    abstract::One hundred and eighty Kunming mice were allotted to three groups in a randomized complete block design, including two treatments and one control. Mice in group 1 were fed a basal diet as control, while mice in groups 2 and 3 were fed the basal diet supplemented with 0.2 mg/kg selenium as sodium selenite (SS) or selen...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0243-5

    authors: Qin S,Huang B,Ma J,Wang X,Zhang J,Li L,Chen F

    更新日期:2015-06-01 00:00:00

  • Microcalorimetric study on the toxic effect of Pb2+ to Tetrahymena.

    abstract::The toxic effect of Pb2+ has been studied in eukaryotic cells by using Tetrahymena as a target. The maximum power (P(m)) and the growth rate constant (k) were determined, which showed that values of P(m) and k were linked to the concentration (C) of Pb2+. The addition of Pb2+ caused a decrease of the maximum heat prod...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-007-0055-3

    authors: Peng L,Weiying Z,Xi L,Xiaojuan C,Chaocan Z

    更新日期:2007-11-01 00:00:00