Abstract:
:The purpose of this study was to evaluate the effects of cadmium-induced peroxidative damage to rat liver, heart, and spleen. Sprague-Dawley rats were injected subcutaneously with a single dose of 25, 125, 500, or 1250 microg Cd/kg and evaluated 6, 12, 24, or 72 h later. Liver, heart, and spleen were analyzed for lipid peroxidation and Fe, Cu, Zn, Se, and Cd concentrations. Data showed that Cd produced enhanced lipid peroxidation in the liver, heart, and spleen. These Cd-induced changes were accompanied by a significant rise in liver, heart, and spleen Fe and Cu, and a fall in spleen Zn and liver, heart, and spleen Se. Concurrent treatment with Se and Cd reduced the Cd-induced alterations in liver, heart, and spleen peroxidation and essential metal levels. Data suggest that lipid peroxidation is associated with cadmium toxicity and that Se was found effective in preventing lipid peroxidation.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Yiin SJ,Chern CL,Sheu JY,Lin THdoi
10.1385/BTER:78:1-3:219subject
Has Abstractpub_date
2000-01-01 00:00:00pages
219-30issue
1-3eissn
0163-4984issn
1559-0720pii
BTER:78:1-3:219journal_volume
78pub_type
杂志文章abstract::The interaction of the vanadyl (IV) cation with N-acetyl-D-galactosamine, D-galactosamine, and D-glucuronic acid has been investigated by electron absorption spectroscopy at different metal to ligand ratios and pH values. In the case of D-glucuronic acid, a more detailed study was undertaken, using differential IR spe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785436
更新日期:1996-02-01 00:00:00
abstract::Divalent metal ions (Fe2+, Cu2+, Zn2+, Ni2+, and Mn2+) induced lipid oxidation in cooked, but not in raw fish. The extent of lipid oxidation, measured by the production of thiobarbituric acid reactive substances (TBRS), was increased with higher concentrations of iron, zinc, and nickel, but was decreased with increasi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783896
更新日期:1992-07-01 00:00:00
abstract::Molybdenum (Mo) is an essential element for human beings and animals; however, high dietary intake of Mo can lead to adverse reactions. Cadmium (Cd) is harmful to health. To investigate the toxicity of Mo combined with Cd in duck kidneys, 240 ducks were randomly divided into six groups and treated with a commercial di...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0348-x
更新日期:2015-11-01 00:00:00
abstract::Zinc is a nutritionally essential trace element required for many biological functions to be successfully carried out. The aim of the present work was to study the influence of zinc on the intestinal absorption of L-threonine and on the aminopeptidase N activity in rabbit jejunum, after in vitro addition and/or oral a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784557
更新日期:1996-07-01 00:00:00
abstract::The aim of this work was to explore the effects of a low- and high-zinc diet and vitamin Aon the distribution of fatty acids in chylomicrons. Mongolian Gerbils were fed a basal diet (for 3 wk) containing 8 or 38 mg zinc/kg of feed (low-zinc group [termed LZ group] and saturated zinc group [termed SZ group], respective...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:112:2:145
更新日期:2006-08-01 00:00:00
abstract::Numerous experiments in vitro and in vivo have shown that an appropriate increase intake of silicon can facilitate the synthesis of collagen and its stabilization and promote the differentiation and mineralization of osteoblasts. In this study, we examined whether ortho-silicic acid restrains the differentiation of os...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02286-6
更新日期:2020-07-16 00:00:00
abstract::Instrumental epithermal neutron activation analysis was used in determining the halide concentration of camel serum. The halides determined were sodium, chloride, bromide, and iodide. Serum was examined when the camels had free access to drinking water, following 10 d of water restriction and 2 h following rapid rehyd...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02796697
更新日期:1987-04-01 00:00:00
abstract::Quin2, a fluorescent calcium probe, has a low affinity for calcium in comparison to its affinities for transition metal ions. Chelation of ferric ion with quin2 strongly enhanced the formation of oxidizing species in the presence of bolus H2O2 as detected with four assays, electron spin resonance with the spin-trap DM...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790098
更新日期:1995-01-01 00:00:00
abstract::This review discusses the development of studies that evaluated the essentiality and requirements of iron from the ancient to the present. The therapeutic effects of iron compounds were recognized by the ancient Greeks and Romans. The earliest recognition of the essentiality of iron was stated by Paracelsus, a disting...
journal_title:Biological trace element research
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s12011-018-1584-7
更新日期:2019-03-01 00:00:00
abstract::A working analytical procedure for selenium determinations by INAA, using gamma spectrometry with a germanium well-type detector, is presented. The spectral line at 400.7 keV is employed, enhanced with the effect of energy summing in true coincidence of cascade photons. The main advantage of the method is high efficie...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917304
更新日期:1994-10-01 00:00:00
abstract::Lung cancer is seriously threatening human health and exposure to trace metals is the most important aetiology for lung cancer. Selected essential/toxic metals (Ca, Mg, Na, K, Fe, Zn, Cu, Sr, Li, Co, Mn, Ni, Cr, Cd and Pb) are measured in the scalp hair and nails of lung cancer patients and controls by atomic absorpti...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9942-6
更新日期:2014-06-01 00:00:00
abstract::Metal nanoparticles synthesized by green methods with the use of microorganisms are currently one of the most closely studied types of nanomaterials. It has accurately been shown that the characteristics of metal nanoparticles generated in the presence of different bacteria vary. For the two isogenic strains of obliga...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01740-4
更新日期:2020-02-01 00:00:00
abstract::Forty-six elements have been detected in fresh banana pulp purchased weekly in Pittsburgh, PA for the past twelve years (1968-1980). Samples were prepared by lyophilization or low temperature ashing. Analyses were performed using X-ray fluorescence spectrometry, optical emission spectrometry, atomic absorption spectro...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789122
更新日期:1981-03-01 00:00:00
abstract::This study aims to examine the effect of zinc supplementation on free-radical formation and antioxidant system in individuals who are actively engaged in wrestling as a sport. The study registered a total of 40 male subjects, of whom 20 were wrestlers and 20 were sedentary individuals. The subjects were equally alloca...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8457-z
更新日期:2010-04-01 00:00:00
abstract::Chromium (Cr), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe) concentrations were quantified in serum (n = 112), milk (n = 112), liver (n = 70), and kidney samples (n = 67) of dairy cows from an iron-steel processing region (Payas-Iskenderun) and from an area free of industrial pollution (Antakya) in Hatay, loc...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:98:1:51
更新日期:2004-04-01 00:00:00
abstract::The influence of dietary supplementation with thiamine on lead (Pb) contents in blood and tissues, blood δ-aminolevulinic acid dehydratase (δ-ALAD) activity, and urinary excretion of δ-aminolevulinic acid (δ-ALA) was evaluated in male Sprague-Dawley rats. Groups of randomly selected animals were given a thiamine-defic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02795566
更新日期:1986-08-01 00:00:00
abstract::Mitochondrial membrane potential is reduced in copper-deficient rat hearts, but it is uncertain if this will lead to the onset of apoptosis. To determine if copper deficiency per se leads to apoptosis, C2C12 cells were made copper deficient by treatment with the copper chelator tetraethylenepentamine (TEPA). In TEPA-t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:106:1:051
更新日期:2005-07-01 00:00:00
abstract::Plasma concentrations of a zinc carrier peptide, namely thymulin, were measured according to a bioassay in young donors, healthy elderly, and patients with senile dementia of Alzheimer's type (SDAT). Thymulin is a hormone released by thymic epithelial cells and its biological activity on cells of immune system is depe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790147
更新日期:1996-01-01 00:00:00
abstract::Lead poisoning is a worldwide health problem, and its treatment is under investigation. The aim of this study was to access the efficacy of Coriandrum sativum (coriander) in reducing lead-induced changes in mice testis. Animal exposed to lead nitrate showed significant decrease in testicular SOD, CAT, GSH, total prote...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8553-0
更新日期:2010-09-01 00:00:00
abstract::This study aimed to determine the effect of excessive fluoride (F) on the morphological characteristics of the small intestine and the contents of serum cytokines in rats. A total of 48 3-week-old healthy female Sprague-Dawley rats were randomly divided into four groups (n = 12). The control group was given deionized ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1503-y
更新日期:2019-06-01 00:00:00
abstract::The interaction of VO2+ with the muchopolysaccharide chondroitin sulfate A (CSA) has been investigated by electron absorption spectroscopy and infrared measurements in aqueous solutions at different pH-values and ligand to metal ratios up to 6:1. The generation of a VO(CSA)2 species could be demonstrated. Coordination...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990487
更新日期:1994-07-01 00:00:00
abstract::Various studies indicate the role of manganese (Mn) in the virulence of pathogens. Salmonella is an intracellular pathogen which is able to multiply within the macrophages. The present study was therefore, designed to assess the effect of Mn supplementation on Salmonella-macrophage interactions particularly in referen...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8406-x
更新日期:2010-01-01 00:00:00
abstract::The metabolic significance of Se in plants is not well documented, though the presence of many selenoenzymes in bacteria and the essentiality of Se in higher animals is established. Since germination is an active process in plant growth and metabolism, the effect of Se was investigated in germinating Vigna radiata L, ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789188
更新日期:1995-05-01 00:00:00
abstract::Evidence linking copper and zinc to hypertension are limited and conflicting. Data from the National Health and Nutrition Examination Survey (NHANES) 2007-2014 were used. Zinc and copper intake from diet and supplements was assessed with 24-h dietary recall. Hypertension was defined as systolic blood pressure (SBP) ≥ ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1320-3
更新日期:2018-12-01 00:00:00
abstract::In this article, we report the results of a case control study carried out on 290 Turkish pregnant women at 5-24 wk of gestation to determine their zinc, folic acid, and vitamin B12 levels in relation to their nutritional and socioeconomic status. The women were divided into two groups (n=145 each), depending on the s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:109:2:105
更新日期:2006-02-01 00:00:00
abstract::Exposure to mobile phone-induced electromagnetic radiation (EMR) may affect biological systems by increasing free oxygen radicals, apoptosis, and mitochondrial depolarization levels although selenium may modulate the values in cancer. The present study was designed to investigate the effects of 900 MHz radiation on th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0032-6
更新日期:2014-08-01 00:00:00
abstract::Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbe...
journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:2011-08-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9716-6
更新日期:2013-07-01 00:00:00
abstract::Concentration of heavy metals (lead (Pb), cadmium (Cd), chromium (Cr), and copper (Cu)) was determined in the liver, gills, kidneys, and muscles of eight edible fish species (Channa punctata, Cirrhinus reba, Labeo rohita, Heteropneustes fossilis, Mystus cavasius, Oreochromis niloticus, Puntius sophore, and Wallago att...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9011-3
更新日期:2011-12-01 00:00:00
abstract::Aspirin is widely used as an antiinflammatory drug especially in children with rheumatic fever arthritis. The diminishing effects of aspirin on antioxidant enzymes and hepato-renal systems at high doses are well-known. It is now evident that the damage at antioxidant system worsens the clinical picture of the disease ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8115-x
更新日期:2008-07-01 00:00:00