Abstract:
:The influence of dietary supplementation with thiamine on lead (Pb) contents in blood and tissues, blood δ-aminolevulinic acid dehydratase (δ-ALAD) activity, and urinary excretion of δ-aminolevulinic acid (δ-ALA) was evaluated in male Sprague-Dawley rats. Groups of randomly selected animals were given a thiamine-deficient diet, a diet containing normal thiamine (20 mg/kg), or a thiamine-supplemented diet (50 mg/kg), along with control drinking water or water containing 100 ppm Pb, for 4 mo. Animals fed the thiamine-supplemented diet (50 mg/kg) and Pb showed decreased urinary excretion of δ-ALA and a decreased inhibition of δ-ALAD activity in blood compared to those given Pb with normal thiamine diet. The liver, kidney, and blood of rats receiving supplemental thiamine also contained significantly less Pb than the other two treatment groups given Pb-containing water. The protective effect of thiamine against Pb toxicity may be attributed to its interference with retention of the metal in body tissue, possibly resulting from the formation of excretable thiamine-lead complexes.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Flora SJ,Sharma RPdoi
10.1007/BF02795566subject
Has Abstractpub_date
1986-08-01 00:00:00pages
137-44issue
2eissn
0163-4984issn
1559-0720journal_volume
10pub_type
杂志文章abstract::Gaucher disease (GD) is most frequent disorder of glycolipid storage. The glucosylceramide accumulation might lead to oxidative stress and changes in lipid profile. Regarding the main role of trace elements in hematopoiesis and oxidative stress, this study was aimed to evaluate the zinc and copper levels, three oxidat...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01709-3
更新日期:2020-01-01 00:00:00
abstract::Changes in the macro and trace element composition of saliva might be indicative for pathological changes in periodontal tissues. However, there is a lack of evidence in the literature showing associations between mineral elements and periodontal status. The aim of this study was to determine whether such associations...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01977-z
更新日期:2020-09-01 00:00:00
abstract:UNLABELLED:There is conflicting evidence regarding the relationship between magnesium deficiency and metabolic syndrome, and a systematic assessment of the literature has not been performed. Our objective was to clarify the association between magnesium levels and metabolic syndrome by performing a meta-analysis. Based...
journal_title:Biological trace element research
pub_type: 杂志文章,meta分析
doi:10.1007/s12011-015-0446-9
更新日期:2016-03-01 00:00:00
abstract::Selenomethionine metabolism and the biochemical basis for its cytotoxicity were analyzed in cultured human and murine lymphoid cells. The metabolic pathways were also addressed, using purified mammalian enzymes and crude tissue extracts. Selenomethionine was found to be effectively metabolized to S-adenosylmethionine ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990463
更新日期:1991-01-01 00:00:00
abstract::The aim of this study was to investigate the effect of lead (Pb) poisoning on nitric oxide (NO) content, inducible nitric oxide synthase (iNOS) activity, the messenger RNA (mRNA) levels of inflammatory factors (nuclear factor-kappa B (NF-κB), tumor necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2), prostaglandin E s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0532-z
更新日期:2016-06-01 00:00:00
abstract::Instrumental epithermal neutron activation analysis was used in determining the halide concentration of camel serum. The halides determined were sodium, chloride, bromide, and iodide. Serum was examined when the camels had free access to drinking water, following 10 d of water restriction and 2 h following rapid rehyd...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02796697
更新日期:1987-04-01 00:00:00
abstract::In the present study, the conditions of analysis by inductively coupled plasma-atomic emission spectrometry (ICP-AES) were investigated. Twenty-six elements (Mg: 25 ppm; Sc: 10 ppm; Ti: 50 ppm; others: 100 ppm) were used as the elements interfering with selected 24 wavelengths. Consequently, the background values in 1...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:87:1-3:211
更新日期:2002-07-01 00:00:00
abstract::Calcium fructoborate (CFB) has been reported as supporting healthy inflammatory response. In this study, we assess the effects of CFB on blood parameters and proinflammatory cytokines in healthy subjects. This was a randomized, double-blinded, placebo-controlled trial. Participants received placebo or CFB at a dose of...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-014-0155-9
更新日期:2015-02-01 00:00:00
abstract::The present study was designed to investigate the effect of mercuric chloride administration on copper, zinc, and iron concentrations in the liver, kidney, lung, heart, spleen, and muscle of rats. The results showed that after dose and time exposure to mercuric chloride, the concentration of mercury in the six tissues...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02910676
更新日期:1997-07-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1213-x
更新日期:2018-09-01 00:00:00
abstract::This study was performed to investigate calcium (Ca), inorganic phosphorus (P), potassium (K), magnesium (Mg), and chlorine (Cl) levels in blood serum at d 60, 100, and 150 of gestation and at d 45 after parturition and to find out the significance of differences for macromineral levels during these stages of single o...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:107:3:247
更新日期:2005-12-01 00:00:00
abstract::Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8757-3
更新日期:2011-08-01 00:00:00
abstract::To examine longitudinal and gestational effects of mineral content in human milk, we analyzed human milk from lactating mothers of premature (PRT, n = 24, < 2000 g birth weight, < 37 wk gestation) and full-term (FT, n = 19, > 2500 g, 39-41 wk gestation), living in Newfoundland, Canada. Samples were collected once a we...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784423
更新日期:1999-03-01 00:00:00
abstract::The present work aimed at assessing passive, innate, and acquired immunity in piglets from sows supplemented with either organic or inorganic selenium (Se). A total of 12 multiparous pregnant sows were randomly allocated to three groups: selenium-deficient, corn and soy-based diet base diet (BD), 0.3 mg Se/kg as hydro...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01754-y
更新日期:2020-03-01 00:00:00
abstract::Plasma concentrations of a zinc carrier peptide, namely thymulin, were measured according to a bioassay in young donors, healthy elderly, and patients with senile dementia of Alzheimer's type (SDAT). Thymulin is a hormone released by thymic epithelial cells and its biological activity on cells of immune system is depe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790147
更新日期:1996-01-01 00:00:00
abstract::The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0477-2
更新日期:2016-04-01 00:00:00
abstract::Selenium (Se) mainly performs its function through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, plays important roles in the normal function of the heart. To investigate the possible relationship between Se and SelW for the regulation of oxidative damage in chicken embryo myo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0529-7
更新日期:2016-06-01 00:00:00
abstract::The concentrations of various trace elements in amniotic fluid (AF) change over the course of pregnancy, with gestational age and fetus growth. The aim of the present study was to evaluate the concentrations of selected essential and toxic elements in AF and their relations to maternal and fetal parameters. The study ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0557-3
更新日期:2016-07-01 00:00:00
abstract::Although recent studies have shown that chromium (as the trivalent ion) is not an essential trace element, it has been demonstrated to generate beneficial effects at pharmacologically relevant doses on insulin sensitivity and cholesterol levels of rodent models of insulin insensitivity, including models of type 2 diab...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/s12011-015-0231-9
更新日期:2015-07-01 00:00:00
abstract::In this study, paraoxonase 1 (PON1; EC 3.1.8.1) was purified from bull semen, and some characteristics of the enzyme were investigated. In vitro inhibition effect of some heavy metals, including Cu(2+), Mn(2+), Cd(2+), Zn(2+), Ni(2+), and Pb(2+), on the activity of the purified enzyme was also investigated. The purifi...
journal_title:Biological trace element research
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journal_title:Biological trace element research
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8625-1
更新日期:2010-12-01 00:00:00
abstract::In the present study, 15 different commercial tea brands sold in Khyber Pakhtunkhwa were collected from the markets. The samples were analyzed for the concentrations of ten selected heavy metals. The metal concentration showed a random distribution in all samples. The mean concentration of Cd, Cu, Mn, Pb, Zn, and Fe w...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02059-1
更新日期:2020-11-01 00:00:00
abstract::Manganese (Mn) is essential for several species and daily requirements are commonly met by an adequate diet. Mn overload may cause motor and psychiatric disturbances and may arise from an impaired or not fully developed excretion system, transporter malfunction and/or exposure to excessive levels of Mn. Therefore, dec...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1531-7
更新日期:2019-03-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8874-z
更新日期:2011-10-01 00:00:00
abstract::In this study, a method of positive matrix factorization (PMF) combined support vector machines (SVMs) was adopted to identify possible sources and apportion contributions for trace element pollution in surface sediments from the Jinjiang River, Southeastern China. Utilizing diagnostics tools, four significant factors...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9576-5
更新日期:2013-03-01 00:00:00
abstract::Mitochondrial membrane potential is reduced in copper-deficient rat hearts, but it is uncertain if this will lead to the onset of apoptosis. To determine if copper deficiency per se leads to apoptosis, C2C12 cells were made copper deficient by treatment with the copper chelator tetraethylenepentamine (TEPA). In TEPA-t...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:106:1:051
更新日期:2005-07-01 00:00:00
abstract::As Cr(III) compounds have been shown to increase insulin sensitivity and decrease plasma cholesterol and triglycerides in rodent models of diabetes and insulin resistance and as colorectal cancer risk has been associated with insulin resistance and diabetes, the effects of the Cr(III) compound Cr3 ([Cr3O(O2CCH2CH3)6(H...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0346-z
更新日期:2015-11-01 00:00:00
abstract::This study was performed with the aim of investigating the concentration of zinc and copper in the blood of healthy alpacas (Vicugna pacos) kept in central Europe and to compare the concentration of Zn and Cu in plasma and in whole blood. A further objective was to evaluate blood Zn and Cu in relation to different mic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1043-x
更新日期:2018-02-01 00:00:00
abstract::This study was conducted to investigate the immune adherence function of erythrocytes and erythrocyte induced by dietary nickel chloride (NiCl2) in broilers fed on a control diet and three experimental diets supplemented with 300, 600, and 900 mg/kg NiCl2 for 42 days. Blood samples were collected from five broilers in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0096-3
更新日期:2014-11-01 00:00:00