Abstract:
:The aim of this study was to investigate the effect of lead (Pb) poisoning on nitric oxide (NO) content, inducible nitric oxide synthase (iNOS) activity, the messenger RNA (mRNA) levels of inflammatory factors (nuclear factor-kappa B (NF-κB), tumor necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2), prostaglandin E synthases (PTGEs), and iNOS), heat shock proteins (HSPs) (HSP27, HSP40, HSP60, HSP70, and HSP90), and the antagonistic effect of selenium (Se) on Pb in chicken livers. One hundred eighty 7-day-old male chickens were randomly divided into four groups and were fed commercial diet and drinking water, Na2SeO3-added commercial diet and drinking water, commercial diet and (CH3OO)2Pb-added drinking water, and Na2SeO3-added commercial diet and (CH3OO)2Pb-added drinking water, respectively, for 30, 60, and 90 days. Then, NO content, iNOS activity, and the mRNA levels of NF-κB, TNF-α, COX-2, PTGEs, iNOS, HSP27, HSP40, HSP60, HSP70, and HSP90 were examined in chicken livers. The results showed that Pb poisoning induced NO content, iNOS activity, and mRNA expression of inflammation factors and HSPs in chicken livers. In addition, Se alleviated Pb-induced increase of inflammation factor and HSP expression in chicken livers.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Wang H,Li S,Teng Xdoi
10.1007/s12011-015-0532-zsubject
Has Abstractpub_date
2016-06-01 00:00:00pages
437-444issue
2eissn
0163-4984issn
1559-0720pii
10.1007/s12011-015-0532-zjournal_volume
171pub_type
杂志文章abstract::In this study, the amount of reduced glutathione (GSH), oxidized glutathione (GSSG), and malondialdehyde (MDA) were determined by high performance liquid chromatography (HPLC), and selenium was determined by using the fluorescence spectrophotometer in eight different species of edible mushrooms. Brittlegill mushroom (...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0715-2
更新日期:2016-12-01 00:00:00
abstract::In this report, we have investigated the role of copper (Cu) and zinc (Zn) in oxidative stress induced by cadmium (Cd) in C6 cells. Cells were exposed to 20 μM Cd, 500 μM Cu, and 450 μM Zn for 24 h. Then, toxic effects, cellular metals levels, oxidative stress parameters, cell death, as well as DNA damage were evaluat...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-011-9265-9
更新日期:2012-06-01 00:00:00
abstract::Copper oxide nanoparticles (CuONPs) are widely used in several products and their release into the environment can cause toxicity to major food crops. In this study, toxic responses as a result of CuONPs exposure were studied in soybean (Glycine max L.) seedlings. The plants were grown in 1/2 strength Murashige and Sk...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0106-5
更新日期:2014-12-01 00:00:00
abstract::In this study, experimental hyperthyroidism was established and used to investigate possible alterations in the calcium (Ca), magnesium (Mg), and zinc (Zn) homeostasis by assessing their concentrations in plasma and erythrocytes. In the L-thyroxine-induced hyperthyroidism condition, the experimental animals show a sig...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02778196
更新日期:1997-05-01 00:00:00
abstract::The phosphorus NMR profile of normal and vanadium-treated chick muscle was obtained in vivo. The data show that the differentiation of breast and thigh muscles in terms of pH, lipid related metabolites, and bioenergetic parameters can be readily followed. Although the vanadium-treated chicks showed substantial retarda...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990427
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abstract::Lead poisoning is a worldwide health problem, and its treatment is under investigation. The aim of this study was to access the efficacy of Coriandrum sativum (coriander) in reducing lead-induced changes in mice testis. Animal exposed to lead nitrate showed significant decrease in testicular SOD, CAT, GSH, total prote...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8553-0
更新日期:2010-09-01 00:00:00
abstract::Synaptosomes are used as an ex vivo model in the investigation of neuronal transmission and neurodegenerative processes. In this study, we aimed to determine the protective effects of boric acid (BA) and curcumin, which have antioxidant and anti-inflammatory properties, on Aβ1-42 induced neurodegenerative damage. Syna...
journal_title:Biological trace element research
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abstract::Cantharellus cibarius Fr. (chanterelle) and Boletus badius Pers. (bay bolete) harvested from natural sites in Poland were used to derive in vitro cultures. The optimal medium composition for cultures was developed. Concentrations of the chosen elements (Zn, Cu, Fe, Mg, Ni, and Cd) in mycelium samples were measured by ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9670-3
更新日期:2013-06-01 00:00:00
abstract::There have been few investigations of trace elements in the urine and hair of populations exposed to high levels of arsenic (As) in drinking water. Therefore, concentrations of selected metals in urine and hair samples from a population in a study area where arsenism was endemic and a control area were determined. It ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1108-x
更新日期:2018-04-01 00:00:00
abstract::Aflatoxin B1 (AFB1) is a mycotoxin that causes cytotoxicity through oxidative damage to its target organs. The liver is the first target of AFB1 damage. The aim of this study was to evaluate the protective effect of selenium on AFB1-induced hepatic mitochondrial damage in ducklings using molecular biological and histo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0189-z
更新日期:2015-02-01 00:00:00
abstract::Previous studies on the endodontic broken stainless steel instruments have mainly focused on retrieval of specimens. However, the systemic consequences of the retained separated instruments need an investigation. The current study aimed to evaluate the correlation between broken stainless steel instruments inside the ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9959-x
更新日期:2014-06-01 00:00:00
abstract::This study evaluated the effects of supplemental dietary chromium (Cr) on the performance, carcass traits, and some serum parameters of broilers under a heat stress (23.9 to 37 °C cycling) condition. A total of 150 1-day-old broiler chicks (Cobb 500) according to a completely randomized design were assigned into five ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9663-2
更新日期:2013-06-01 00:00:00
abstract::Hyperlipidemia is one of the major risk factors for atherosclerosis and ischemic heart disease. Chromium (Cr) mineral is playing a crucial role in glucose and lipid homeostasis. The aim of this study was to evaluate the protective effects of combined chromium picolinate (CrPic) and atorvastatin treatment against hyper...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1010-6
更新日期:2017-12-01 00:00:00
abstract::Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is the most common human enzymopathy in the world. Trace elements are important for normal hematopoiesis and can play a role in acute hemolytic anemia induced by G-6-PD deficiency. For this purpose, we studied two groups consisting of 10 male children who are G-6-P...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:99:1-3:041
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abstract::Extracellular Ca2+-influx induced by trivalent metal ions (Fe3+, Al3+, Cr3+, In3+, Ga3+, and La3+) in Ehrlich carcinoma cells is enhanced by ATP. This action seems to be related to the high coordination capacity of the ATP ligand that inhibits the polymerization of the solvated cations taking place at physiological pH...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02820027
更新日期:1998-04-01 00:00:00
abstract::Responses of photosystem I and II activities of Microcystis aeruginosa to various concentrations of Cu(2+) were simultaneously examined using a Dual-PAM-100 fluorometer. Cell growth and contents of chlorophyll a were significantly inhibited by Cu(2+). Photosystem II activity [Y(II)] and electron transport [rETRmax(II)...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0039-z
更新日期:2014-08-01 00:00:00
abstract::Age-related changes in the concentrations of constituent elements in the brains of rats and mice 1 wk to 24 mo old were determined with inductively coupled plasma-mass spectrometry (ICP-MS) and inductively coupled plasma-atomic emission spectrometry (ICP-AES). Seventeen elements could be determined with reasonable acc...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:2:145
更新日期:2001-05-01 00:00:00
abstract::The current information about the effect of physical exercise on the body concentrations of several minerals is still limited, both in the acute (short-term) and adaptive (long-term) responses. So, this manuscript aims, on the one hand, to assess the possible differences on basal levels of cobalt (Co), copper (Cu), an...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
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journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
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更新日期:2016-08-01 00:00:00
abstract::Calsyntenin-2 (Clstn2) and calsyntenin-3 (Clstn3) are the members of the cadherin superfamily and function to regulate the postsynaptic activity. Both proteins are known to play an important role in memory and learning. This study was designed to test the hypothesis that exposure of mothers to Pb in drinking water may...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02241-5
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abstract::Serum selenium levels were determined cross-sectionally in 57 HIV-infected patients who were classified according to the Centers for Disease Control (CDC) 1993 classification system. Mean serum selenium levels were lower in CDC stage II (58.7 +/- 12.2 micrograms/L; p < 0.01; n = 18) and stage III (47.6 +/- 11.3 microg...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02778982
更新日期:1997-01-01 00:00:00
abstract::Zinc concentrations in the dorsal horn of spinal cord are important for wound healing, neurological function, and reproduction. However, the response of the spinal cord to alterations in dietary zinc is unknown in rats after spinal cord injury (SCI). The current study explored cellular zinc levels and zinc transporter...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9414-9
更新日期:2012-11-01 00:00:00
abstract::Parenteral administration of mercuric chloride (HgCl2) to rats enhanced lipid peroxidation in liver, kidney, lung, testis, and serum (but not in heart, spleen, or muscle), as measured by the thiobarbituric acid reaction for malondialdehyde (MDA) in fresh tissue homogenates and body fluids. After sc injection of HgCl2 ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789461
更新日期:1996-05-01 00:00:00
abstract::A series of microcalorimetric experiments were performed to investigate the effect of La(3+) on the formation of the competent state of Escherichia coli HB101 by using a LKB-2277 BioActivity Monitor at 37 C. The thermogenic curves in the absence and in the presence of La(3+) were obtained. Based on these curves, we ca...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:91:3:267
更新日期:2003-03-01 00:00:00
abstract::In three fully crossed, factorially arranged, completely randomized experiments, female weanling rats were fed a basal diet (containing about 10 ng of nickel and 2.3 μg of iron/g) supplemented with graded levels of nickel and iron. Iron was supplemented to the diet in experiment 1 at levels of 0, 25, 50, and 100 μg/g ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990121
更新日期:1981-09-01 00:00:00
abstract::Vanadium compounds maintain euglycemic effects in diabetic rats long after drug withdrawal and bis(α-furancarboxylato)oxovanadium(IV) (BFOV) possesses potent antidiabetic effects in diabetic rats. Here, we investigated the treatment and posttreatment effects of BFOV in diabetic Kuo Kondo [1, 2] with Ay gene (KKAy) mic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9689-5
更新日期:2013-06-01 00:00:00
abstract::The aim of this study was to establish the possible effects of the sampling protocol (between-breast, within-feed, and diurnal differences) and the mother's personal factors (age, parity, iron supplementation, smoking habits, and lactation period) on the copper, iron, and zinc contents in human milk. One hundred thirt...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
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更新日期:2000-09-01 00:00:00
abstract::The relaxation rates (1/T(1) and 1/T(2)) in cysts have already been analyzed in terms of materials such as albumin, cholesterol, manganese, iron, and copper. However, the relaxivities of these materials have not been determined yet. In this work, five sets containing the ions, albumin, and cholesterol were prepared by...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8170-3
更新日期:2008-12-01 00:00:00
abstract::Quantitative analysis of follicular fluid and granulosa cells from small, medium and large antral atretic follicles of goat (Capra hircus) ovaries was conducted to study the alterations in trace elements viz zinc (Zn), copper (Cu), manganese (Mn), and iron (Fe). The zinc content was lower in the follicular fluid (0.99...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8700-7
更新日期:2011-06-01 00:00:00
abstract::Suppression subtractive hybridization analysis in our laboratory recently revealed that transferrin mRNA may be elevated in Sedeficient rat liver. In this work, we compared expression in rat liver of genes for transferrin, transferrin receptor, ferritin light and heavy chains, and iron-regulatory proteins 1 and 2 in S...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:74:1:55
更新日期:2000-04-01 00:00:00