Abstract：
:In a recent paper in Nature, show that the immunoreceptor PD-1 is upregulated by "exhausted" T cells during the chronic phase of viral infection in mice. Remarkably, blocking the interaction between PD-1 and its ligand, PD-L1, reactivates these T cells and reduces viral load.
journal_name
Celljournal_title
Cellauthors
Okazaki T,Honjo Tdoi
10.1016/j.cell.2006.01.022subject
Has Abstractpub_date
2006-02-10 00:00:00pages
459-61issue
3eissn
0092-8674issn
1097-4172pii
S0092-8674(06)00115-2journal_volume
124pub_type
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