Viral RNAs: lessons from the enemy.

Abstract:

:Viruses are adept at evolving or co-opting genomic elements that allow them to maximize their replication potential in the infected host. This evolutionary plasticity makes viruses an invaluable system to identify new mechanisms used not only by viruses but also by vertebrate cells to modulate gene expression. Here, I discuss the identification and characterization of viral mRNA structures and noncoding RNAs that have led to important insights into the molecular mechanisms of eukaryotic cells.

journal_name

Cell

journal_title

Cell

authors

Cullen BR

doi

10.1016/j.cell.2009.01.048

subject

Has Abstract

pub_date

2009-02-20 00:00:00

pages

592-7

issue

4

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(09)00132-9

journal_volume

136

pub_type

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